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Hepatobiliary Surgery and Nutrition 2021年第6期10卷 902-905页

作者： Jan P.Jonas henrik Petrowsky Swiss HPB and Transplantation Center Department of SurgeryUniversity Hospital ZurichZurichSwitzerland HPB Center Department of SurgeryClinic FavoritenViennaAustria

Life expectancy of patients with colorectal liver metastasis(CRLM)significantly improved over the last decades due to the induction of multimodal effective treatment strategies including perioperative chemotherapy and advanced surgical *** conversion chemotherapy,previously unresectable CRLMs can be converted to a resectable situation and amenable to procedures such as associating liver partition and portal vein ligation(ALPPS)(1).A recent publication in HBSN has extensively reviewed ALPPS as a concept in the treatment of *** review article by Glinka et al.(2)focuses on the evolvement of this novel procedure and describes in detail the gradual changes accompanying this procedure’s evolvement since ***,the authors highlight several aspects crucial for the best possible outcome after this procedure including patient selection,future liver remnant,technical aspects,safety,morbidity,mortality and oncological results.

关键词： chemotherapy colorectal treatment

An arctic low-energy house as experimental setup for studies of heat dynamics of buildings

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Frontiers of Architectural Research 2013年第4期2卷 488-499页

作者： Philip Delft Andersen Carsten Rode henrik Madsen DTU Compute Richard Pedersens Plads Technical University of Denmark Building 322 Kongens Lyngyb DK-2800 Denmark DTU Civil Engineering Brovej Bygning 118 Technical University of Denmark Kongens Lyngyb DK-2800 Denmark

This paper addresses the difficulties in pinpointing reasons for unexpectedly high energy consumption in construction, and in low-energy houses especially. Statistical methods are applied to improve the insight into the energy performance and heat dynamics of a building based on consumption records and weather data. Dynamical methods separate influences from outdoor temperature, solar radiation, and wind on the energy consumption in the building. The studied building is a low-energy house in Sisimiut, GreenLand. Weather conditions like large temperature differences between indoors and outdoors throughout tong winters, strong winds, and very different circumstances regarding solar radiation compared to areas where Low-energy houses are usually built, make the Location very interesting for modeling and testing purposes. In 2011 new measurement equipment was installed in the house, which will be used to develop more detailed models of the heat dynamics and energy performance in relation to different meteoroLogicaL variables, heating systems, and user behavior. This type of models is known as a graybox model and is been introduced in this paper.

关键词： Low-energy houses Heat dynamics Arctic climate Statistical modeling Graybox modeling

Finite-time consensus protocols for multi-dimensional multi-agent systems

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Control Theory and Technology 2020年第4期18卷 419-430页

作者： Jieqiang Wei Bart Besselink Junfeng Wu henrik Sandberg Karl H.Johansson Ericsson Global AI Accelerator Torshamnsgatan 21StockholmSweden Bernoulli Institute for Mathematics Computer Science and Artificial IntelligenceUniversity of GroningenP.O.Box 4079700 GroningenAKThe Netherlands College of Control Science and Engineering Zhejiang University310027 HangzhouChina Division of Decision and Control Systems KTH Royal Institute of Technology10044 StockholmSweden

A fnite.-time consensus protocol is proposed for multi -dimensional multi- agent systems, using direction peserving signumcontrols. Flipp solutions and nonsmooh analysis tehniques are adopted to handle discontinuities. Suficient and ncessaryconditions are provided to guarantee infinte time convergence and boundedness of the solutions. It turns out that the numberof agents which have cotinuous contol law plays an ssenan role in fnite-tine conerence In adidio it is shown thatthe unit bals itoduced bylp, norms. where p ∈[1,∞] , are inariat for the closed lop.

关键词： Multi-agent systems Network consensus Finite time convergence Nonsmooth analysis

Effects of a novel bacterial phytase expressed in Aspergillus Oryzae on digestibility of calcium and phosphorus in diets fed to weanling or growing pigs

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Journal of Animal Science and Biotechnology 2013年第2期4卷 102-111页

作者： Ferdinando Nielsen Almeida Rommel Casilda Sulabo Hans henrik Stein Department of Animal Sciences University of Illinois

In 2 experiments, 48 weanling （initial BW： 13.5 ± 2.4 kg, Exp. 1） were used to determine effects of a novel bacterial 6-phytase and 24 growing pigs （initial BW： 36.2 ± 4.0 kg, Exp. 2） expressed in Aspergillus oryzae on the apparent total tract digestibility （ATTD） of phosphorus and calcium in corn-soybean meal diets fed to weanling and growing pigs. In Exp. 1 and 2, pigs were randomly allotted to 6 dietary treatments using a randomized complete block design and a balanced 2 period changeover design, respectively. In both experiments, 6 diets were formulated. The positive control diet was a corn-soybean meal diet with added inorganic phosphorus （Exp. 1：0.42 and 0.86% standardized total tract digestible phosphorus and total calcium, respectively; Exp. 2：0.32 and 0.79% standardized total tract digestible phosphorus and total calcium, respectively）. A negative control diet and 4 diets with the novel phytase （Ronozyme HiPhos, DSM Nutritional Products Inc., Parsippany, N J） added to the negative control diet at levels of 500, 1,000, 2,000, and 4,000 phytase units （FYT）/kg were also formulated. In Exp. 1, the ATTD of phosphorus was greater （P 〈 0.01） for the positive control diet （60.5%） than for the negative control diet （40.5%）, but increased （linear and quadratic, P 〈 0.01） as phytase was added to the negative control diet （40.5% vs. 61.6%, 65.1%, 68.7%, and 68.0%）. The breakpoint for the ATTD of phosphorus （68.4%） was reached at a phytase inclusion level of 1,016 FYT/kg. In Exp. 2, the ATTD of phosphorus was greater （P〈 0.01） for the positive control diet （59.4%） than for the negative control diet （39.8%） and increased （linear and quadratic, P〈 0.01） as phytase was added to the negative control diet （39.8% vs. 58.1%, 65.4%, 69.1%, and 72.8%）. The breakpoint for the ATTD of phosphorus （69.1%） was reached at a phytase inclusion level of 801 FYT/kg. in conclusion, the novel bacterial 6-phytase improved the ATTD of phosphorus and calcium in both weanling and growing pigs.

关键词： Calcium Digestibility Phosphorus Phytase Pigs

Swedish rape offenders——a latent class analysis

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Forensic Sciences Research 2021年第2期6卷 124-132页

作者： Ardavan Khoshnood henrik Ohlsson Jan Sundquist Kristina Sundquist Department of Clinical Sciences Center for Primary Health Care ResearchLund UniversityMalmoSweden

Sweden has witnessed an increase in the rates of sexual crimes including *** of who the offenders of these crimes are is therefore of importance for *** aimed to study characteristics of individuals convicted of rape,aggravated rape,attempted rape or attempted aggravated rape(abbreviated rape+),against a woman≥18years of age,in *** using information from the Swedish Crime Register,offenders between 15 and 60years old convicted of rapeþbetween 2000 and 2015 were *** on substance use disorders,previous criminality and psychiatric disorders were retrieved from Swedish population-based registers,and Latent Class Analysis(LCA)was used to identify classes of rapeþoffenders.A total of 3039 offenders were included in the analysis.A major-ity of them were immigrants(n=1800;59.2%)of which a majority(n=1451;47.7%)were born outside of *** LCA identified two classes:Class A-low offending class(LOC),and Class B—high offending class(HOC).While offenders in the LOC had low rates of previous criminality,psychiatric disorders and substance use disorders,those included in the HOC had high rates of previous criminality,psychiatric disorders and substance use *** HOC may be composed by more“traditional”criminals probably known by the police,the LOC may represent individuals not previously known by the *** two separated classes,as well as our finding in regard to a majority of the offenders being immi-grants,warrants further studies that take into account the contextual characteristics among these offenders.

关键词： Forensic sciences Sweden crime sex crimes rape offender characteristics crime prevention latent class analysis

First attempt to produce experimental Campylobacter concisus infection in mice

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World Journal of Gastroenterology 2008年第45期14卷 6954-6959页

作者： Rune Aabenhus Unne Stenram Leif Percival Andersen henrik Permin sa Ljungh Department of Clinical Microbiology National University Hospital (Rigshospitalet) Department of Pathology University of Lund Department of Infectious Control and Prevention National University Hospital (Rigshospitalet) Department of Internal Medicine Bispebjerg Hospital Department of Medical Microbiology Dermatology and Infection Lund University

AIM： TO infect mice with atypical Campylobacter concisus （C. concisus） for the first time. METHODS： Three separate experiments were conducted in order to screen the ability of five clinical C. concisus isolates of intestinal origin and the ATCC 33237 type strain of oral origin to colonize and produce infection in immunocompetent BALB/cA mice. The majority of the BALB/cA mice were treated with cyclophosphamide prior to C. concisus inoculation to suppress immune functions. Inoculation of C. conc/sus was performed by the gastric route. RESULTS： C. concisus was isolated from the liver, ileum and jejunum of cyclophosphamide-treated mice in the first experiment. No C. concisus strains were isolated in the two subsequent experiments. Mice infected with C. concisus showed a significant loss of body weight from day two through to day five of infection but this decreased at the end of the first week. Histopathological examination did not consistently find signs of inflammation in the gut, but occasionally microabscesses were found in the liver of infected animals. CONCLUSION： Transient colonization with C. concisus was observed in mice with loss of body weight. Future studies should concentrate on the first few days after inoculation and in other strains of mice.

关键词： Animal model BALB/cA mice Campylobacter concisus Colonization Infection

Diversity patterns, environmental drivers and changes in vegetation composition in dry inter-Andean valleys

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Journal of Plant Ecology 2017年第3期10卷 461-475页

作者： Catalina Quintana Marco Girardello Anders S.Barfod henrik Balslev Department of Bioscience Ecoinformatics and Biodiversity GroupAarhus UniversityNy Munkegade 114DK-8000 Aarhus CDenmark Departamento de Ciencias Biológicas Pontificia Universidad Católica del EcuadorAv.12 de Octubre 1076Apartado postal 17012184QuitoEcuador

Aims We studied diversity,patterns of endemism and turnover of veg-etation composition in dry inter-Andean valleys(DIAVs)where lit-tle is known about the influence of the abiotic drivers controlling plant species composition and occurrences,and the life forms that contribute most toα-andβ-diversity,*** study was focused on DIAVs located in the highlands(800-2800 m)around the Equator(1°N-5°S).The following questions were addressed:(i)what differences exist between endemic and non-endemic species in terms of species number,frequency and abundance?(ii)are pat-terns ofα-andβ-diversity correlated with latitude?(iii)what are the major environmental drivers controlling spatial patterns in species composition and occurrence?Methods We established 63 transects of 5×100 m in areas with DIAV vegetation,impacted as little as possible by human *** each transect,all mature trees and shrubs were identified and counted to determine their *** coverage of terrestrial herbs was *** additive models were used to quantify the relationship betweenα-andβ-diversity with *** recordα-diversity,we used the exponential Shannon *** Sørensen index was used to measureβ-diversity or species *** used canonical correspondence analysis to deter-mine species composition and generalized linear mixed models to quantify simultaneously the determinants of species occur-rence across species and *** models were evaluated using the Akaike information *** analyses were run separately for trees,herbs and *** Findings Overall,we found that shrubs was the most diverse life form,constituting 43%(12%endemic)of the 313 species,followed by herbs(36%;11.5%endemic)and trees(20%;5%endemic).Trees comprise mostly species with low abundance(e.g.30 individuals ha^(−1)),includ-ing four endemic *** of the e

关键词： endemics α-diversity β-diversity life forms Ecuador

Transactive control:a framework for operating power systems characterized by high penetration of distributed energy resources

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Journal of Modern Power Systems and Clean Energy 2017年第3期5卷 451-464页

作者： Junjie HU Guangya YANG Koen KOK Yusheng XUE henrik W.BINDNER Center for Electric Power and Energy Technical University of DenmarkCopenhagenDenmark Netherlands Organization for Applied Research TNOThe HagueThe Netherlands State Grid Electric Power Research Institute NanjingChina

The increasing number of distributed energy resources connected to power systems raises operational challenges for the network operator, such as introducing grid congestion and voltage deviations in the distribution network level, as well as increasing balancing needs at the whole system level. Control and coordination of a large number of distributed energy assets requires innovative approaches. Transactive control has received much attention due to its decentralized decision-making and transparent characteristics. This paper introduces the concept and main features of transactive control, followed by a literature review and demonstration projects that apply to transactive control. Cases are then presented to illustrate the transactive control framework. At the end, discussions and research directions are presented, for applying transactive control to operating power systems, characterized by a high penetration of distributed energy resources.

关键词： Distributed energy resources Distribution system operation Smart grids Transactive control

Morphology of living cells cultured on nanowire arrays with varying nanowire densities and diameters

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Science China(Life Sciences) 2018年第4期61卷 427-435页

作者： Zhen Li henrik Persson Karl Adolfsson Stina Oredsson Christelle N. Prinz Division of Solid State Physics Lund University Lund 22100 Sweden Nano Lund Lund University Lund 22100 Sweden Department of Biology Lund 22362 Sweden Present address: Translational & Bioengineering Program Mechanical and Industrial Engineering University of Toronto Toronto MSG 1M1 ON Canada

Vertical nanowire arrays are increasingly investigated for their applications in steering cell behavior. The geometry of the array is an important parameter, which influences the morphology and adhesion of cells. Here, we investigate the effects of array geometry on the morphology of MCF7 cancer cells and MCF10A normal-like epithelial cells. Different gallium phosphide nanowire array-geometries were produced by varying the nanowire density and diameter. Our results show that the cell size is smaller on nanowires compared to flat gallium phosphide. The cell area decreases with increasing the nanowire density on the substrate. We observed an effect of the nanowire diameter on MCF10A cells, with a decreased cell area on 40 nm diameter nanowires, compared to 60 and 80 nm diameter nanowires in high-density arrays. The focal adhesion morphology depends on the extent to which cells are contacting the substrate. For low nanowire densities and diameters, ceils are lying on the substrate and we observed large focal adhesions at the cell edges. In contrast, for high nanowire densities and diameters, cells are lying on top of the nanowires and we observed point-like focal adhesions distributed over the whole cell. Our results constitute a step towards the ability to fine-tune cell behavior on nanowire arrays.

关键词： nanowires cell morphology diameter density aspect ratio

Low-level retention forestry, certification, and biodiversity: case Finland

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Ecological Processes 2019年第1期8卷 580-592页

作者： Timo Kuuluvainen henrik Lindberg Ilkka Vanha-Majamaa Petri Keto-Tokoi Pekka Punttila Department of Forest Sciences University of HelsinkiP.O.Box 27FI-00014 HelsinkiFinland Häme University of Applied Sciences P.O Box 230FI-13100 HämeenlinnaFinland Natural Resources Institute Finland(Luke) Latokartanonkaari 9FI-00790 HelsinkiFinland Tampere University of Applied Sciences PO Box 21FI-33521 TampereFinland Finnish Environment Institute Latokartanonkaari 11FI-00790 HelsinkiFinland

In managed forests,leaving retention trees during final harvesting has globally become a common approach to reconciling the often conflicting goals of timber production and safeguarding biodiversity and delivery of several ecosystem *** Finland,the dominant certification scheme requires leaving low levels of retention that can benefit some specific ***,species responses are dependent on the level of retention and the current low amounts of retention clearly do not provide the habitat quality and continuity needed for declining and redlisted forest species which are dependent on old living trees and coarse woody *** factors contribute to this ***,the ecological benefits of the current low retention levels are further diminished by monotonous standwise use of retention,resulting in low variability of retention habitat at the landscape ***,the prevailing timber-oriented management thinking may regard retention trees as an external cost to be minimized,rather than as part of an integrated approach to managing the ecosystem for specific ***,the main obstacles of development may still be institutional and *** development of retention practices in Finland indicates that the aim has not been to use ecological understanding to attain specific ecological sustainability goals,but rather to define the lowest level of retention that still allows access to the *** conclude that prevailing retention practices in Finland currently lack ecological credibility in safeguarding biodiversity and they should urgently be developed based on current scientific knowledge to meet ecological sustainability goals.

关键词： Boreal forest Ecological sustainability Legacy structure Forest dynamics Forest certification Forest structure PEFC certification