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极早产儿慢性肺病的产前预测因子

世界核心医学期刊文摘（儿科学分册） 2006年第5期2卷 16-16页

作者： henderson-smart d.j. Hutchinson j.L. donoghue d.A. 郭战宏 Centre for Perinatal Health Services Research University of Sydney Sydney NSW 2006 AustraliaProf

Objective: To identify prenatal risk factors for chronic lung disease (CLd) at 36 weeks postmenstrual age in very preterm infants. Population: data were colle cted prospectively as part of the ongoing audit of the Australian and New Zealan d Neonatal Network (ANZNN) of all infants born at less than 32 weeks gestation a dmitted to all tertiary neonatal intensive care units in Australia and New Zeala nd. Methods: Prenatal factors up to 1 minute of age were examined in the subset of infants born at gestational ages 22-31 weeks during 1998-2001, and who surv ived to 36 weeks postmenstrual age (n=11 453). Factors that were significantly associated with CLd at 36 weeks were entered into a multivariate logistic regress ion model. Results: After adjustment, low gestational age was the dominant risk factor, with an approximate doubling of the odds with each week of decreasing ge stational age from 31 to less than 25 weeks (trend P d a dose-response effect: the lower the birth weight for gestational age, the greater the risk, with infants below the third centile having 5.67 times greater odds of CLd than those between the 25th and 75th centile (trend P d risk for male infa nts (odds ratio 1.51 (95%confidence interval 1.36 to 1.68), P d data show that the prenatal factors low gestational age, low birth weight for gestational age, and male sex significantly predict the development of chronic respiratory insufficiency in very preterm infants and may assist clinical decision about delivery.

关键词：产前因素慢性肺病早产儿预测因子新生儿重症监护病房澳大利亚危险因素停经后新西兰出生时

Selection of digital fabrication technique in the construction industry--A multi-criteria decision-making approach

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 977-997页

作者： M.P.SALAIMANIMAGUdAM j.jAYAPRAKASH department of Structural and Geotechnical Engineering School of Civil EngineeringVellore Institute of TechnologyVellore 632014India

digital fabrication techniques,in recent decades,have provided the basis of a sustainable revolution in the construction ***,selecting the digital fabrication method in terms of manufacturability and functionality requirements is a complex *** paper presents alternatives and criteria for selection of digital fabrication techniques by adopting the multi-criteria decision-making *** alternatives considered in the study are concrete three-dimensional(3d)printing,shotcrete,smart dynamic casting,material intrusion,mesh molding,injection concrete 3d printing,and thin forming *** criteria include formwork utilization,reinforcement incorporation,geometrical complexity,material enhancement,assembly complexity,surface finish,and build *** demonstrates different multi-criteria decision-making techniques,with both subjective and objective weighting *** given ranking is based on the current condition of digital fabrication in the construction *** study reveals that in the selection of digital fabrication techniques,the criteria including reinforcement incorporation,build area,and geometrical complexity play a pivotal role,collectively accounting for nearly 70% of the overall *** the evaluated techniques,concrete 3d printing emerged as the best performer,however the shotcrete and mesh molding techniques in the second and third positions.

关键词： digital fabrication multicriteria decision-making concrete 3d printing

Abalone shell-derived Mg-doped mesoporous hydroxyapatite microsphere drug delivery system loaded with icariin for inducing apoptosis of osteosarcoma cells

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Biomaterials Translational 2024年第2期5卷 185-196页

作者： Liu K. Cheng M. Huang H. Yu H. Zhao S. Zhou j. Tie d. Wang j. Pan P. Chen j. Marine College Shandong University Shandong Province Weihai China State Key Laboratory of Mineral Processing Beijing China College of Biological Science and Technology Fuzhou University Fujian Province Fuzhou China

Hydroxyapatite (HAP) porous microspheres with very high specific surface area and drug loading capacity, as well as excellent biocompatibility, have been widely used in tumour therapy. Mg2+ is considered to be a key factor in bone regeneration, acting as an active agent to stimulate bone and cartilage formation, and is effective in accelerating cell migration and promoting angiogenesis, which is essential for bone tissue repair, anti-cancer, and anti-infection. In this study, abalone shells from a variety of sources were used as raw materials, and Mg2+-doped abalone shell-derived mesoporous HAP microspheres (Mg-HAP) were prepared by hydrothermal synthesis as Mg2+/icariin smart dual delivery system (ICA-Mg-HAP, IMHA). With increasing of Mg2+ doping, the surface morphology of HAP microspheres varied from collapsed macroporous to mesoporous to smooth and non-porous, which may be due to Mg2+ substitution or coordination in the HAP lattice. At 30% Mg2+ doping, the Mg-HAP microspheres showed a more homogeneous mesoporous morphology with a high specific surface area (186.06 m2/g). The IMHA microspheres showed high drug loading (7.69%) and encapsulation rate (83.29%), sustained Mg2+ release for more than 27 days, sustained and stable release of icariin for 60 hours, and good responsiveness to pH (pH 6.4 > pH 5.6). In addition, the IMHA delivery system stimulated the rapid proliferation of bone marrow mesenchymal stem cells and induced apoptosis in MG63 cells by blocking the G2 phase cycle of osteosarcoma cells and stimulating the high expression of apoptotic genes (Bcl-2, caspase-3,-8,-9). This suggests that the abalone shell-based IMHA may have potential applications in drug delivery and tumour therapy. © 2024, Chinese Medical Multimedia Press Co Ltd. All rights reserved.

关键词： abalone shell drug delivery hydroxyapatite microspheres magnesium doping osteosarcoma

Transformation Efficiency of Sulfur for a Mulberry Leaf-Silkworm Cocoon System in the Lower-Middle Reaches of the Yangtze River, China

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Pedosphere 2005年第3期15卷 281-285页

作者： ZHAOYan-Wen HUZheng-Yi CAOZhi-Hong j.d.BEATON A.M.henderson M.X.FAN XUCheng-Kai InstituteofSoilScience ChineseAcademyofSciencesNanjing210008（China） FernzSulFerWorksInc. P.O.Box9IrricanaAB.TOM1BO（Canada） TheSulphurInstitute WashingtonDC20036（USA） CollegeofAgriculture NanjingAgri.Univ.KeyLab.ofCropGrowthRegulationMinistryofAgri.Nanjing210095（China）／／InstituteofSoilScienceChineseAcademyofSciencesNanjing210008（China）

Cocoon samples were collected from fifty-two mulberry gardens with high, intermediate, and low silkworm cocoon productivities in the lower-middle reaches of the Yangtze River in the six China’s provinces of jiangsu, jiangxi, Anhui, Fujian, Hunan, and Hubei to determine the transformation efficiency of S from mulberry leaves to silkworm cocoons, and to evaluate the sulfur cycle (uptake and output) in the mulberry leaf-silkworm cocoon system with typical mulberry gardens in the lower-middle reaches of the Yangtze River in China. The transformation efficiency of sulfur (TES) from mulberry leaves into silkworm cocoons in the high-productivity mulberry gardens was significantly lower (P ductivity gardens. For the high-productivity mulberry gardens the TES from mulberry leaves into the cocoon shells was significantly higher (P d mulberry gardens. Producing 1 kg dry cocoon in mulberry gardens required uptake of about 20 g S, however 1 kg of dry cocoon only removed about 4 g S. Therefore, recycling of these organic wastes with silkworm cultivation was important for sulfur balances.

关键词： mulberry leaves silkworm cocoon sulfur transformation efficiency

Lessons learned from the Youngstown, Ohio induced earthquake sequence from january 2011 to january 2012

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journal of Rock Mechanics and Geotechnical Engineering 2017年第5期9卷 783-796页

作者： A.P.Morris d.A.Ferrill G.R.Walter A.M.Price K.j.smart R.j.Skoumal M.R.Brudzinski B.S.Currie Southwest Research Institute Culebra Road 6220 San Antonio TX 78238-5166 USA United States Geological Survey Earthquake Science Center 345 Middlefield Rd Building 3A RM 113 Menlo Park CA 94025 USA department of Geology and Environmental Earth Science Miami University Oxford OH 45056 USA

The Youngstown earthquake sequence of 2011 is one of the clearest examples of inadvertently induced seismicity for which detailed documentation is *** this paper,we investigate(i) likely stress states in the vicinity of the injection well,(ii) a range of likely permeability scenarios,and(iii) relatively simple methods by which induced seismicity can be evaluated and *** use relocated hypocenters from the seismic sequence to construct a basement fault structure,which is then used to serve as a reference surface within the basement,and on which we calculate the effects of pore pressure changes induced by the injection activities of the Northstar #1 injection *** also deduce an in situ(preinjection) strike-slip stress regime,where ρ2≈ρ3,and it is consistent with both recent earthquake data and published stress estimates for the *** the reactivation characteristics of the basement are known or assumed,a critical or threshold slip tendency can be determined and the basement faults can be analyzed for the likelihood of reactivation in a perturbed pore pressure *** of well injection pressures and simulated pore pressure perturbations within the basement below the injection well indicates that permeability anisotropy is necessary to generate sufficient pore pressure perturbation to induce fault *** of the well’s injection history show that our estimate of in situ stress state,coupled with a highly anisotropic permeability structure,can generate sufficient pore pressure perturbation on the inferred basement structure to cause reactivation,potentially slipping an area of approximately 4×10~5 m~2.

关键词： Induced seismicity Wastewater injection Slip tendency

Highly Efficient Back‑End‑of‑Line Compatible Flexible Si‑Based Optical Memristive Crossbar Array for Edge Neuromorphic Physiological Signal Processing and Bionic Machine Vision

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Nano-Micro Letters 2024年第11期16卷 323-339页

作者： dayanand Kumar Hanrui Li dhananjay d.Kumbhar Manoj Kumar Rajbhar Uttam Kumar das Abdul Momin Syed Georgian Melinte Nazek El‑Atab smart Advanced Memory Devices and Applications(SAMA)LaboratoryElectrical and Computer EngineeringComputer Electrical Mathematical Science and EngineeringKing Abdullah University of Science and Technology(KAUST)23955‑6900 ThuwalSaudi Arabia

The emergence of the Internet-of-Things is anticipated to create a vast market for what are known as smart edge devices,opening numerous opportunities across countless domains,including personalized healthcare and advanced *** 3d integration,edge devices can achieve unprecedented miniaturization while simultaneously boosting processing power and minimizing energy ***,we demonstrate a back-end-of-line compatible optoelectronic synapse with a transfer learning method on health care applications,including electroencephalogram(EEG)-based seizure prediction,electromyography(EMG)-based gesture recognition,and electrocardiogram(ECG)-based arrhythmia *** experiments on three biomedical datasets,we observe the classification accuracy improvement for the pretrained model with 2.93%on EEG,4.90%on ECG,and 7.92%on EMG,*** optical programming property of the device enables an ultralow power(2.8×10^(-13) j)fine-tuning process and offers solutions for patient-specific issues in edge computing ***,the device exhibits impressive light-sensitive characteristics that enable a range of light-triggered synaptic functions,making it promising for neuromorphic vision *** display the benefits of these intricate synaptic properties,a 5×5 optoelectronic synapse array is developed,effectively simulating human visual perception and memory *** proposed flexible optoelectronic synapse holds immense potential for advancing the fields of neuromorphic physiological signal processing and artificial visual systems in wearable applications.

关键词： Neuromorphic computing Electrophysiological signal Artificial vision system Image recognition Memristor

Timing of Crop Removal Has Limited Effect on Merlot Grape and Wine Composition

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Agricultural Sciences 2015年第4期6卷 456-465页

作者： Petra d. King Richard E. smart daniel j. McClellan School of Viticulture and Wine Science Eastern Institute of Technology Hawke’s Bay New Zealand smart Viticulture 31 North Corner Newlyn near Penzance TR185JG Cornwall UK

Cluster removal during the growing season is a widely utilized vineyard management practice aiming to balance crop load to the capacity of the vine to ripen the fruit. Research was undertaken over two growing seasons (2008-2009) in Hawke’s Bay, a cool climate region of New Zealand, to establish the influence of different times of crop removal on Merlot vine growth and fruit and wine composition. The test vineyard was high-yielding, to 23 t/ha, and vigorous. A commercial standard of apical cluster thinning to remove 20 clusters per vine from vines with ca 44 clusters in 2008 and ca 47 in 2009, was carried out on uniform vigour, 7yo grafted Merlot vines at nine times between prebloom and six weeks post veraison. The 2009 season was naturally higher yielding. Timing of crop removal had no significant effect on vine vegetative growth in terms of enhanced shoot growth as measured by cane weights at pruning, or canopy leaf density. Time of thinning also had no effect on overall grape yield, cluster weight, and berry weight. There were limited effects on fruit ripeness in one season (2009) at the veraison time of thinning only, with increased Brix and lower TA levels. Berry anthocyanin concentrations were enhanced by cluster thinning in 2008, and more so when undertaken at or soon after veraison. There was however no influence of removal timing on anthocyanin levels and total phenolics in the wines. Grape ripeness, must and wine composition tended to respond more from crop removal at veraison than the other times evaluated. data suggest that vine response was modified by excessive leafiness and shading.

关键词： Crop Removal Timing Merlot Grape Composition Wine

Ultrahigh frame rate digital light projector using chip-scale LEd-on-CMOS technology

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Photonics Research 2022年第10期10卷 2434-2446页

作者： NAVId BANI HASSAN FAHIMEH dEHKHOdA ENYUAN XIE jOHANNES HERRNSdORF MICHAEL j.STRAIN ROBERT henderson MARTIN d.dAWSON Institute of Photonics Department of PhysicsUniversity of StrathclydeTechnology and Innovation CentreGlasgow G11RDUK School of Engineering Institute for Integrated Micro and Nano SystemsUniversity of EdinburghEdinburgh EH93JLUK

digital light projector systems are crucial components in applications,including computational imaging,fluorescence microscopy,and highly parallel data *** technology based on digital micromirror displays are limited to absolute frame rates in the few tens of kiloframes per second and require the use of external light sources and coupling ***,to realize gray-scale pixel values using duty cycle control,frame rates are reduced proportionally to the number of gray levels *** we present a self-emissive chip-scale projector system based on micro-LEd pixels directly bonded to a smart pixel CMOS drive *** 128×128 pixel array can project binary patterns at up to 0.5 Mfps and toggle between two stored frames at megahertz *** projector has a 5-bit gray-scale resolution that can be updated at up to 83 kfps,and can be held in memory as a constant bias for the binary pattern ***,the projector can be operated in a pulsed mode,with individual pixels emitting pulses down to a few nanoseconds in ***,this mode can be used in conjunction with the high-speed spatial pattern *** a demonstration of the data throughput achievable with this system,we present an optical camera communications application,exhibiting data rates of>5 Gb/s.

关键词： frame frames light

运动性刺激在治疗早产儿呼吸暂停中的作用(摘要)

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中国实用儿科杂志 2002年第7期17卷 443-443页

作者： Osborn d A henderson-smart dj 陈大鹏中国循证医学中心四川大学华西第二医院儿科

本系统评价最近一次修订在1998年11月24日.如有必要,对Cochrane评价要定期审查和更新.目的:在有呼吸暂停的早产儿,使用运动性刺激是否可减少临床性呼吸暂停和心动过缓的发作(发作次数减少>50%),以及减少使用机械通气(IPPV)或持续性正压... 详细信息

本系统评价最近一次修订在1998年11月24日.如有必要,对Cochrane评价要定期审查和更新.目的:在有呼吸暂停的早产儿,使用运动性刺激是否可减少临床性呼吸暂停和心动过缓的发作(发作次数减少>50%),以及减少使用机械通气(IPPV)或持续性正压通气(CPAP)和降低神经系统发育不良的发生等所具有的临床意义的程度,而没有临床上重要的副作用.

关键词：运动性刺激早产儿呼吸暂停