检索结果-南通市图书馆

Effects of temperature and hydric environment on survival of the Panamanian Golden frog infected with a pathogenic chytrid fungus

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Integrative Zoology 2010年第2期5卷 143-153页

作者： heidi M.BUSTAMANTE Lauren J.LIVO Cynthia CAREY Department of Integrative Physiology University of ColoradoBoulderColoradoUSA

Considerable controversy exists concerning whether or not climate changes(particularly global warming)are causing outbreaks of a lethal amphibian pathogen,the chytrid fungus Batrachochytrium dendrobatidis(Longcore,Pessier&*** 1999).In the present study,groups of Panamanian golden frogs(Atelopus zeteki Dunn,1993),a critically endangered amphibian thought to be nearly extinct in Panama,were exposed to varying dosages of zoospores of Batrachochytrium dendrobatidis,temperatures and hydric environments in order to learn whether this species is susceptible to this pathogen and,if so,how environmental factors affect *** pathogen proved to be highly lethal for *** exposed to a dosage of 100 Bd zoospores survived significantly(Pfrogs housed at 23℃survived significantly(Pfrogs held in dry conditions survived significantly longer than those in wet conditions(Pf these frogs in the field,but they inform the discussion about how environmental conditions can have an impact on the interaction between a susceptible amphibian and this *** data do not support the contention that rising global temperatures are necessary to cause the death of amphibians infected with this pathogen because the pathogen was equally lethal at 17 as at 23℃,and frogs at the warmer temperature lived significantly longer than those at the cooler one.

关键词： amphibian declines Atelopus zeteki Batrachochytrium dendrobatidis chytridiomycosis climatelinked-epidemic hypothesis

Applied and Environmental Chemistry of Animal Manure:A Review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pedosphere 2016年第6期26卷 779-816页

作者： Zhongqi HE Paulo H.PAGLIARI heidi M.WALDRIP USDA-ARS Southern Regional Research Center Department of Soil Waterand ClimateUniversity of MinnesotaSouthwest Research and Outreach Center USDA-ARS Conservation and Production Research Laboratory

Animal manure consists of predominantly urine and feces,but also may contain bedding materials,dropped feed,scurf,and other farming *** is typically applied to soils as fertilizer for agricultural *** estimated amount of manure produced in 12 major livestock-producing countries is 9 × 109 Mg of manure *** is rich in plant ***,manure is also considered as an environmental pollutant when it is over-applied to cropland or following runoff into surface *** can also in?uence global climate change via emissions of methane（CH4） and nitrous oxide（N2O）.Thus,increased and updated knowledge of applied and environmental chemistry of animal manure is needed to shed light on the research and development of animal manure utilization and minimization of its adverse environmental *** advances in basic and applied studies of manure major components,organic matter,phosphorus,and nitrogen,primarily related to US livestock production are summarized in this *** focus was placed on three notable challenges for future manure research:1) soil application of animal manure,2)manure phytate phosphorus,and 3) manure nitrogen *** review may contribute to the global effort in sustainable and environmentally sound agriculture by stimulating new ideas and directions in animal manure research,and promoting application of knowledge and insight derived from manure research into improved manure management strategies.

关键词：畜禽粪便应用程序环境化学综述植物营养成分全球气候变化动物粪便农业废物

Preface for the article collection “Ecohydrological Processes and Ecosystem Services”

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ecological Processes 2018年第1期7卷 78-80页

作者： Ge Sun Dennis W.Hallema heidi Asbjornsen Eastern forest Environmental Threat Assessment Center Southern Research StationU.S.Department of Agriculture Forest Service920 Main Campus Dr.Suite 300RaleighNC 27606USA Oak Ridge Institute for Science and Education U.S.Department of EnergyOak RidgeTNUSA Institute for the Study of Earth Oceansand SpaceUniversity of New HampshireDurhamNHUSA

Water is essential to life on ***,the study of interactions between ecological and hydrological processes,is fundamental to our understanding and quantification of services provided by *** knowledge of ecohydrology is incomplete due to the complex nature of ecosystems,which are constantly changing under multiple stresses from air pollution to climate change,from deforestation to urbanization,and from soil erosion to soil *** services,the goods and services that ecosystems provide for human wellbeing,are increasingly adopted as a framework worldwide for ecological restoration and conservation,watershed management,and sustainable development policy making.

关键词： services soil Services

Resistance to cis- and carboplatin initiated by epigenetic changes in ovarian cancer patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Drug Resistance 2019年第2期2卷 271-296页

作者： heidi Schwarzenbach Peter B.Gahan Department of Tumor Biology University Medical Center Hamburg-EppendorfHamburg 20246Germany fondazione“Enrico Puccinelli”Onlus Perugia 06126Italy

Initially,most ovarian tumors respond to the treatment with platinum components,but frequently recurrence occurs within the following two years in advanced ovarian cancer *** this regard,previous studies have shown changes in the epigenetic patterns in ovarian cancer that are linked with resistance to cis-and carboplatin ***,epigenetic changes mediated by a treatment with cis-or carboplatin could identify such patients who do or do not respond to this ***,an understanding of the impact of platinum on epigenetics in ovarian cancer is important in overcoming platinum *** this review,we delineate epigenetic abnormalities in cis-and carboplatin-resistant ovarian tumors,such as changes in DNA methylation,histone modifications and deregulation of microRNAs,and discuss the potential of epigenetic therapies in combination with platinum.

关键词： Ovarian cancer carboplatin cisplatin resistance DNA methylation histone modifications microRNAs

Circulating non-coding RNAs in recurrent and metastatic ovarian cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Drug Resistance 2019年第3期2卷 399-418页

作者： heidi Schwarzenbach Peter B.Gahan Department of Tumor Biology University Medical Center Hamburg-EppendorfHamburg 20246Germany fondazione“Enrico Puccinelli”Onlus Perugia 06123Italy

Ovarian cancer has a poor outcome because it is usually detected at advanced tumor stages,and the majority of the patients develop disease relapse as a result of chemotherapy *** most lethal gynecological malignancy metastasizes within the peritoneal fluid or ascites to pelvic and distal *** ovarian cancer progression and metastasis,small non-coding RNAs(ncRNAs),including long noncoding RNAs and microRNAs have been recognized as important *** dysregulation modulates gene expression and cellular signal pathways and can be detected in liquid *** this review,we provide an overview on circulating plasma and serum ncRNAs participating in tumor cell migration and invasion,and contributing to recurrence and metastasis of ovarian *** will also discuss the development of potential,novel therapies using ncRNAs as target molecules or tumor markers for ovarian cancer.

关键词： Ovarian cancer recurrence metastasis epithelial-mesemchmal transition non-coding RNAs chemotherapy tumor markers

Predictive value of exosomes and their cargo in drug response/resistance of breast cancer patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cancer Drug Resistance 2020年第1期3卷 63-82页

作者： heidi Schwarzenbach Peter B.Gahan Department of Tumor Biology University Medical Center Hamburg-EppendorfHamburg 20246Germany fondazione“Enrico Puccinelli”Onlus Perugia 06123Italy

Exosomes are small extracellular vesicles engaged in intercellular communication in both healthy and tumor *** released by the primary tumor,they transfer their cargo including nucleic acids,proteins,and lipids to target cells,thus modulating the character and fate of the recipient *** propagating their oncogenic content,exosomes are able to promote tumor progression,angiogenesis,metastases,and drug *** functions as delivery vehicles of biological material make exosomes promising biomarkers for the early prediction of disease progression and drug resistance in breast cancer,as well as for therapeutic targeting of molecules to treat this deadly *** the present review,we accentuate the relevance of exosomes as vehicles of prognostic and predictive markers and target molecules,and describe their potential therapeutic applications as drug cargo *** made an extensive literature research to clarify the association of their cargo,including exosomal DNA and RNA molecules,with the propagation of drug resistance.

关键词： Breast cancer exosomes exosomal DNA mRNA non-coding RNAs microRNAs lncRNAs

Evidence for the polyphyly of Encoelia and Encoelioideae with reconsideration of respective families in Leotiomycetes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

fungal Diversity 2017年第1期82卷 183-219页

作者： Kadri Pärtel Hans-Otto Baral heidi Tamm Kadri Põldmaa Institute of Ecology and Earth Sciences University of TartuLai 40EE-51005 TartuEstonia Mycological Collections Institute of Agricultural and Environmental SciencesEstonian University of Life SciencesTartuEstonia Blaihofstraße 42 72074 TübingenGermany

This study focuses on the genus Encoelia and the subfamily Encoelioideae in the morphologically and ecologically diverse *** 28S and 18S rDNA as well as tef1,rpb1 and rpb2 were sequenced for 70 *** analyses revealed Encoelia and Encoelioideae to be highly polyphyletic,with species distributed among eight major *** fascicularis and *** belonged to Sclerotiniaceae and were combined in a new genus,*** comprised *** and Dencoeliopsis johnstonii,both accepted in *** type of Encoelia,***,was closely related to species of Velutarina,Cenangiopsis and *** species together with members of Hemiphacidiaceae formed a clade conforming to the emended concept of Cenangiaceae,introduced *** resurrected family,Cordieritidaceae,comprised ***,*** and species of Ameghiniella,Cordierites,Diplocarpa and Ionomidotis,characterised by inamyloid asci and a positive ionomidotic *** glauca showed closest affinities with Chlorociboria species in Chlorociboriaceae.A new genus,Xeropilidium,with sporodochial and pycnidial synanamorphs,was described for the distinct encoelioid member of the Chaetomellaceae,previously known as *** and ecological synapomorphies were distinguished from convergent characters to delimit monophyletic taxa including encoelioid *** of public sequences from various biological samples in ITS rDNA analyses allowed identification of sequenced organisms at species,genus,or family level and added information on the ecology of seversal *** of Cenangiaceae appeared to be widespread as *** of encoelioid genera in Chaetomellaceae and Sclerotiniaceae added xylicolous saprotrophs to these families.

关键词： Environmental sequencing fungicolous ascomycetes Helotiaceae Lichenicolous fungi forest pathogens Taxonomy

Treatment of refractory diabetic macular edema with a fluocinolone acetonide implant in vitrectomized and non-vitrectomized eyes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2018年第12期11卷 1951-1956页

作者： Alberto La Mantia Alan Hawrami heidi Laviers Sudeshna Patra Hadi Zambarakji Eye Treatment Centre Whipps Cross University Hospital Barts Health National Health System Foundation Trust

AIM: To report real-life data on the use of an intravitreal fluocinolone acetonide implant in the treatment of refractory diabetic macular edema(DME) in pars plana vitrectomized(PPV) and non-PPV ***: This was a comparative retrospective observational study of 23 eyes with chronic DME. Bestcorrected visual acuity(BCVA) and central macular thickness(CMT) were recorded at baseline, 1, 4 and 12 mo. Descriptive statistics and non-parametric tests were performed to analyze and compare PPV and non-PPV eyes. RESULTS: Seven PPV and 16 non-PPV eyes were included in the study. Median BCVA in the non-PPV group varied from 0.65 logMAR [Interquartile range(IQR): 0.40] at baseline to 0.42 logMAR(IQR: 0.40) at 12 mo. Median CMT varied from 430 μm(IQR: 131.3) at baseline to 317 μm(IQR: 107.5) at 12 mo. Median BCVA in the PPV group varied from 0.60 logMAR(IQR: 0.62) at baseline to 0.74 logMAR(IQR: 0.34) at 12 mo. Median CMT varied from 483 μm(IQR: 146) at baseline to 397 μm(IQR: 132) at 12 mo. Of 0/7 eyes and 1/16 eyes in the PPV and non-PPV eyes respectively had a baseline visual acuity of 6/12 or better(0.3 logMAR). At last follow up, 1/7 and 5/16 eyes in the PPV and non-PPV group respectively achieved a visual acuity of 6/12 or ***: Visual outcomes are modest following the use of the fluocinolone acetonide implant for chronic DME. The steroid implant is a useful treatment option in the management of refractory DME in vitrectomized and non-vitrectmized eyes.

关键词： diabetic macular edema fluocinolone acetonide intravitreal implant steroid vitrectomy

Population differentiation at a regional scale in spadefoot toads： contributions of distance and divergent selective environments

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Current Zoology 2016年第2期62卷 193-206页

作者： Amber M. RICE Michael A. MCQUILLAN heidi A. SEEARS Joanna A. WARREN Department of Biological Sciences Lehigh University BethLehem PA 18015 USA

The causes of population differentiation can provide insight into the origins of early barriers to gene flow. Two key drivers of population differentiation are geographic distance and local adaptation to divergent selective environments. When reproductive isolation arises because some populations of a species are under selection to avoid hybridization while others are not, population differentiation and even speciation can result. Spadefoot toad populations that are sympatric with a congener have undergone reinforcement. This reinforcement has resulted not only in increased reproductive isolation from the congener, but also in the evolution of reproductive isolation from nearby and distant conspecific allopatric populations. We used multiple approaches to evaluate the contributions of geographic distance and divergent selective environments to population structure across this regional scale in , based on genotypes from six nuclear microsatellite markers. We compared groups of populations varying in both geographic location and in the presence of a congener. Hierarchical f-statistics and results from cluster analyses and discriminant analyses of principal components all indicate that geographic distance is the stronger contributor to genetic differentiation among populations at a regional scale. However, we found evidence that adaptation to divergent selective environments also contributes to population structure. Our findings highlight how variation in the balance of evolutionary forces acting across a species' range can lead to variation in the relative contributions of geographic distance and local adaptation to population differentiation across different spatial scales.

关键词：种群分化距离和环境蟾蜍人口结构地理位置生殖隔离标记基因型