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TLR3 Ligand-Induced Accumulation of Activated Splenic Natural Killer Cells into Liver

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Cellular & Molecular Immunology 2005年第6期2卷 449-453页

作者： Jing Wang~1 Jiawei Xu~1 Weici Zhang~1 Haiming Wei~1 Zhigang Tian~(1,2) ~1Institute of Immunology,School of Life Sciences,University of Science and Technology of China,hefei,anhui,China ~2Institute of Immunology,School of Life Sciences,University of Science and Technology of China,443 Huangshan Road,hefei 230027,anhui,China. Institute of Immunology School of Life Sciences University of Science and Technology of China Hefei Anhui China.

It has been revealed that poly I：C is a potent stimulator for NK cells, which can induce NK cell rapid activation and preferential accumulation into liver. However, the process mediating the influx of NK cells remains obscure. In this study, we found that poly I：C administration increased the portion and absolute number of NK cells in liver, but largely decreased those in spleen. There were no obvious changes of these lymphocytes in other immune organs. The results from splenic adoptive transfer and splenectomy showed that the recruited spleen NK cells contributed to the accumulation of NK cells in liver, and this process was regulated by the production of chemokines and the presence of T cells. This investigation will help to understand the enhanced immune cell recruitment in liver upon viral infection. Cellular ＆ Molecular Immunology. 2005;2（6）：449-453.

关键词： liver spleen NK poly I:C recruitment

ELECTRON IMPACT IONIZATION OF A HYDROGENIC ION AT INTERMEDIATE AND LOW ENERGIES

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原子与分子物理学报 1999年第2期 3-5页

作者： CHEN Zhangjin a,b ,XU Kezun b( a Department of Physics, anhui University hefei 230039) ( b Laboratory on the Electron Collision Spectroscopy, University of Science and Technology of China, hefei 230027)

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关键词： Electron impact ionization Triple differential cross section He +

Synthesis, Crystal Structure and Electrochemical Properties of 2-Chlorobenzaldehyde Thiosemicarbazone

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Chinese Chemical Letters 1997年第5期8卷 459-460页

作者： Sheng Yi ZHANG Yu Peng TIAN(Department of chemistry, anhui University, hefei, 230039)(Coordination Chemistry Institute State Key Laboratory of Naning University. Nanjing. 210093) anhui UNIV DEPT CHEM HEFEI 230039 PEOPLES R CHINA INST COORDINAT CHEM STATE KEY LAB NANJING 210093 PEOPLES R CHINA

The title compound crystallized in space goups P2(1)/c with Z=4, in a unit cell of dimensions, a=12.964(4), b=5.131(5), c=14.970(1)Angstrom; V=9331(1) Angstrom(3) Dc=1.429gcm(-3), mu=0.541mm(-1), R=0.045, Rw=0.059. The equilibrium constant of the ligand with CdBr2 was obtained by polarographic method. Crystal structure determination revealed that the molecule is in transconformation and non-hydrogen atoms of the molecule are in one plane except N(3) atom.

关键词： Crystal Structure and Electrochemical Properties of 2-Chlorobenzaldehyde Thiosemicarbazone Synthesis

Formation Principles of Similar Systems

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Systems Science and Systems Engineering 1996年第3期6卷 281-286页

作者： ZHOU Meili(Department of Mechanical Engineering, anhui Institute of Technology 111 Lu An Rood, hefei 230069, anhui, People’s Republic of China)

In this paper some new concepts, i.e, Ordered Structure of Systems, Universal Information, Strength of Information Field are proposed. Based on Similarity System Theory and Similology, five principles for investigating similarity formation, i.e., Principle of Ordered Structue, Information Principle, Consanguining Principle, Coadaptation Principle and Governing Principle are introduced. The origin of similar systems, and way of similarity formation are expounded. Thus, formation principles of similar systems is presented.

关键词： similarity systems theory similology universal information information fetid principle of ordered structure information principle consanguinty principle coadaptation principle govering principle.

Bioaccumulation of hexachlorobenzene in Eisenia foetida at dierent aging stages

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Journal of Environmental Sciences 2009年第7期21卷 948-953页

作者： GAO Hongjian School of Resources and Environmental Science, anhui Agricultural University, hefei 230036, China.

The impacts of contact time on the extractability, the availability of bexachlorobenzene （HCB） in different soils （paddy soil, red soil, and fluvo-aquic soil） and bioaccumulation in earthworm Eisenia foetida were investigated under controlled conditions in laboratory. Results indicated that the aging rate of HCB displaying a biphasic character in different soils： a rapid aging in the first 60 d followed by a slow aging in the next 120 d incubation time. Moreover, most of extractable HCB （about 90%） decline occurred in the first 60 d after HCB was spiked into the soils. The aging rate of HCB in the paddy soil was higher than that in the fluvo-aquic soil or the red soil. The amount of HCB accumulated in the earthworms and its accumulative ability, expressed as a bioaccumulation factor （BAF）, declined as the aging time increased from 1 to 180 d. Although the extractable HCB decreased with increasing residence time in soil, much of HCB could still be accumulated by earthworms （457.6-984.3 ng/g） through bioaccumulation, which poses a potential risk to soil ecological safety.

关键词： HCB soil extractability bioavailability earthworm

EB RULES FOR SELECTING THE BEST EXPONENTIAL POPULATION

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Systems Science and Mathematical Sciences 1989年第4期2卷 317-324页

作者：高集体 Department of Mathematics Anhui UniversityHefeiChina

In this paper,we obtain empirical Bayes（EB）procedures for selecting the bestamong k different exponential populations（the form of the conditional probability *** population is f4（xi/bi）=bi exp（-bixi）,xi,bi∈（0,∞）,i=1,2,…,k）.These rulesare based on the EB estimators of bi.We show that,under the squared error loss,the Bayesrisk of the EB estimators converges to the related minimum Bayes risks with rates of conver-gence at Jeast of order O(n-q).Further,for the selection problem,the rates of convergenceof the proposed selection rules are shown to be at least of order O(n（-q）/2 where q can bearbitrarily close to 1/5 or 1 under suitable conditions.

关键词： Empirical Bayes rules exponential population asympotic optimal convergence rates

A KIND OF NONPARAMETRIC TESTS ABOUT THE CROSSING POINT BETWEEN TWO CONTINUOUSDISRIBUTION FUNCTIONS

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Systems Science and Mathematical Sciences 1998年第1期11卷 1-8页

作者： LI Ninglling CHEN Guijing(Department of Mathematus, anhui Unwersity, hefei 23OO39, China)

Based on combining rank statistics of two samples, a new kind of nonparametricdistribution-free tests about unique crossing point between two continuous distributionfunctions has been proposed. By simuiation study, we see that these test procedures possesshigher power than other test procedures under the same conditions recently proposed inthe literature.

关键词： Rank statistics criterion function Browman bridge process distributionfree test.

Crystal Structure,Electrochemical Properties and Third-order Nonlinear Optical Response of 4-Methyloxy benzaldehyde Thiosemicarbazone and Its Copper(Ⅱ)Complex

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Chinese Chemical Letters 1998年第6期9卷 599-602页

作者： Sheng Yi ZHANG Yu Peng TIAN Yin Han ZHANG Fu Xin XIE and Chun Ying DUAN(Department of Chendstry, anhui University, hefei, 230039)(Department of Applied Chemistry, University of Science and Technolgy of China, hefei,230026)(State Key Laboratory of Coor Department of Chemistry Anhui University Hefei 230039 China Department of Applied Chemistry Univ. of Sci./Technology of China Hefei 230026 China State Key Lab. of Coord. Chemistry Nanjing University Nanjing 210093 China

The crystal structUre of the title ligand and its copper (Ⅱ) complex was determined bysingle crystal X-ray diffraction. The electrochendcal properties and the third-order nonlinearoptical response of the ligand and i... 详细信息

关键词： Crystal Structure Electrochemical Property Nonlinear Optical Response Complex

cDNA cloning,sequence analysis,and recombinant expression of akitonin beta,a C-type lectin-like protein from Agkistrodon acutus

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Acta Pharmacologica Sinica 2004年第03期25卷 118-123页

作者： Xiang-dong ZHA1,2,Jing LIU1,Kang-sen XU3 1 School of Life Science,University of Science and Technology,hefei 230026 School of Life Science,anhui University,2 hefei 230039 National Institute for Control of Pharmaceuticals and Biological Products,Beijing 100050,China 3 School of Life Science University of Science and Technology School of Life Science Anhui University National Institute for Control of Pharmaceuticals and Biological Products Beijing 100050 China

AIM: To clone the cDNA of a new member of snake venom C-type lectin-like proteins, to study its structure- function relationships and to achieve its recombinant production. METHODS: PCR primers were designed based on the homology and cDNA was amplified by RT-PCR using total RNA from snake venom gland as the template. The PCR products were cloned into the plasmid pGEM-T and sequenced. The deduced protein sequence was analyzed with some bioinformatic programs. A recombinant expression plasmid was constructed using pBAD- TOPO as vector and transformed into *** TOP10 competent cells. RESULTS: A novel cDNA sequence encod- ing akitonin β was found and accepted by GenBank (accession number AF387100). Akitonin β consists of a typical carbohydrate recognition domain (CRD) of C-type lectins, and it is homologous with other snake venom C-type lectin-like proteins. It was predicted to be a platelet antagonist. Upon induction with arabinose rAkitonin β express- ing in E coli was achieved at a high level (superior to 150 mg/L). The recombinant fusion protein exhibited inhibitory activities on rat platelet aggregation in vitro. CONCLUSION: A new member of snake venom C-type lectin-like proteins was discovered and characterized, and an efficient recombinant expression system was estab- lished for its production.

关键词： snake venoms cDNA akitonin C-type lectin-like proteins recombinant proteins structure- activity relationship