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Corrigendum to“Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review”[***.14(2024)100919]

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Journal of Pharmaceutical Analysis 2024年第6期14卷 934-936页

作者： Hemanth P.R.Vikram Tegginamath Pramod Kumar Gunjan Kumar Narasimha M.Beeraka Rajashree Deka sheik mohammed suhail sandeep Jat Namitha Bannimath Gayatiri Padmanabhan Ravandur s.Chandan Pramod Kumar Bannimath Gurupadayya Department of Pharmaceutical Chemistry JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Xenone Healthcare Pvt.Ltd. New Delhi110076India Department of Pharmaceutics JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Department of Human Anatomy I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow119991Russian Federation Department of Pharmacology Raghavendra Institute of Pharmaceutical Education and Research(RIPER)Ananthapuramu515721India Herman B.Wells Center for Pediatric Research Department of PediatricsIndiana University School of MedicineIndianapolisIN46202USA Animal Physiology and Biochemistry Laboratory Department of ZoologyGauhati UniversityGuwahati781014India Department of Pharmacology JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Department of Pharmaceutical Analysis National Institute of Pharmaceutical Education and Research(NIPER)-GuwahatiChangsari781101India Department of Pharmacology University of GalwayGalwayH91 TK33Ireland

Original statement in the section 2:*** search Our primary screening of 180 articles yielded the relevant data for this *** selection A total of 180 articles spanning from 1960 to the present day,including original research,reviews,case reports and studies reporting nitrosamine impurities above the no-observed-adverse-effect levels(NOAEL)established by regulatory agencies,were initially *** the primary screening,we considered factors such as relevance,publication date,access to the full article text,and content.

关键词： statement initially spanning

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Microbial,immune and antioxidant responses of Nile tilapia with dietary nano-curcumin supplements under chronic low temperatures

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Aquaculture and Fisheries 2024年第1期9卷 57-65页

作者： mohammed F.El Basuini Mohamed A.A.Zaki Abdelaziz M.El-Hais Mohamed G.Elhanafy Emad H.El-Bilawy Amr I.Zaineldin Mohamed F.A.Abdel-Aziz Ibrahim A.Abouelsaad Ibrahim TEl-Ratel Kumbukani Mzengereza Ronick s.shadrack Islam I.Teiba Faculty of Agriculture Tanta UniversityTanta31527Egypt King salman International University South Sinai46618Egypt Faculty of Agriculture Alexandria UniversityAlexandria21526Egypt Animal Health Research Institute(AHRI-DOKI) Agriculture Research CenterGiza12619Egypt Fish Rearing Lab. Aquaculture DivisionNational Institute of Oceanography and FisheriesAlexandria21556Egypt Horticulture Department Faculty of AgricultureDamanhour UniversityDamanhur22511Egypt Department of Poultry Production Faculty of AgricultureDamietta UniversityDamietta34517Egypt Laboratory of Aquatic Animal Nutrition Faculty of FisheriesKagoshima UniversityKagoshima890-0065Japan Department of Aquatic and Fisheries science Mzuzu UniversityMzuzuPrivate Bag 201Malawi Faculty of Aquaculture and Marine Fisheries Arish UniversityArish45516Egypt

A 56-day feeding period was performed to investigate the possible impacts of dietary nano curcumin(0,50,100,150,and 200 ppm)on the growth,nutrient utilization,non-specific immune parameters,antioxidants in Nile tilapia under chronic low temperature(21.02±0.11◦C).Fishes(n=225;Initial weight=4.39±0.08 g/fish)were randomly stocked at 15 fish/tank for five experimental groups in *** low-temperature circumstances,dietary curcumin in nano form showed no notable alteration in growth variable,nutrient efficiency,digestive enzymes efficiency,biometric indices,survival rates,and hematological ***,the serum of fishes with nano curcumin diets under low-temperature stress displayed higher total protein as well as lower glucose,cortisol,and total cholesterol compared with the control ***,fish fed nano curcumin diets displayed higher lysozyme and bactericidal activities compared to the control group and the best performance was found at dietary nano curcumin level of≥100 ***,groups fed the basal diet demonstrated the poorest antioxidant capacity,and the best superoxide dismutase(sOD)and glutathione peroxidase(GPx)existed in fish with nano curcumin diets while the best catalase(CAT)efficiency occurred at higher nano curcumin levels≥100 *** addition,higher counts of intestinal microbiota in terms of total bacterial count(TBC),total yeast and molds count(TYMC),and coliform were noticed in fish consumed the basal diet compared to groups fed on nano curcumin *** conclusion,incorporating nano curcumin at a level of≥100 mg/kg diet(particularly at 150 mg/kg)improved a non-specific immune response,antioxidant,and healthier gastrointestinal microbiota in Nile tilapia under chronic low-temperature stress.

关键词： Nano curcumin Gastrointestinal microbiota Antioxidants Non-specific immune responses Temperature stress

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Numerical Modeling and Technico-Economic Analysis of a Hybrid Energy Production system for self-Consumption: Case of Rural Area in the Comoros

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Journal of Power and Energy Engineering 2024年第5期12卷 24-59页

作者： Fahad Maoulida Mohamed Aboudou Kassim Rabah Djedjig Ahmed Ihlal mohammed El Ganaoui LERMAB Laboratory of Studies and Research on Wood Material IUT of Longwy University of Lorraine Cosnes-et-Romain Longwy France LEMA Energy and Applied Mechanics Laboratory Faculty of Sciences and Techniques University of Comoros Moroni Comoros IREMIs Institute University of Mayotte Mayotte France LMER Laboratory of Materials and Renewable Faculty of Sciences University Ibn Zohr BP Agadir Morocco

This study aims to provide electricity to a remote village in the Union of Comoros that has been affected by energy problems for over 40 years. The study uses a 50 kW diesel generator, a 10 kW wind turbine, 1500 kW photovoltaic solar panels, a converter, and storage batteries as the proposed sources. The main objective of this study is to conduct a detailed analysis and optimization of a hybrid diesel and renewable energy system to meet the electricity demand of a remote area village of 800 to 1500 inhabitants located in the north of Ngazidja Island in Comoros. The study uses the Hybrid Optimization Model for Electric Renewable (HOMER) Pro to conduct simulations and optimize the analysis using meteorological data from Comoros. The results show that hybrid combination is more profitable in terms of margin on economic cost with a less expensive investment. With a diesel cost of $1/L, an average wind speed of 5.09 m/s and a solar irradiation value of 6.14 kWh/msup>2sup>/day, the system works well with a proportion of renewable energy production of 99.44% with an emission quantity of 1311.407 kg/year. 99.2% of the production comes from renewable sources with an estimated energy surplus of 2,125,344 kWh/year with the cost of electricity (COE) estimated at $0.18/kWh, presenting a cost-effective alternative compared to current market rates. These results present better optimization of the used hybrid energy system, satisfying energy demand and reducing the environmental impact.

关键词： Hybrid system Rural Area Electrification Comoros Techno-Economic Analysis PV-Wind-Diesel-Battery Meteorological Data HOMER Energy Pro

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Brain metabolic profile assessed by magnetic resonance spectroscopy in children with Down syndrome:Relation to intelligence quotient

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World Journal of Clinical Pediatrics 2023年第5期12卷 310-318页

作者： Nesreen safwat El Feil heba s Elmahdy Rasha Ahmed Elmahdy Ahmed Abd-Elbasset Aboelezz heba s Dawoud mohammed Al-Beltagi Department of Pediatrics Faculty of MedicineTanta UniversityTanta 31527Al GharbiaEgypt Department of Radiology University Medical CenterDr.Sulaiman Al-Habib Medical GroupManama 26671ManamaBahrain Department of Pediatrics University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain Department of Pediatrics University Medical CenterDr.Sulaiman Al-Habib Medical GroupManama 26671ManamaBahrain

BACKGROUND Down syndrome(Ds)is one of the most common causes of intellectual *** with Ds have varying intelligence quotient(IQ)that can predict their learning *** To assess the brain metabolic profiles of children with Ds and compare them to standard controls,using magnetic resonance spectroscopy(MRs)and correlating the results with *** This case-control study included 40 children with Ds aged 6-15 years and 40 age and sex-matched healthy children as *** was used to evaluate ratios of choline/creatine(Cho/Cr),N-acetyl aspartic acid/creatine(NAA/Cr),and myoinositol/creatine(MI/Cr(in the frontal,temporal,and occipital lobes and basal ganglia and compared to controls and correlated with *** Children with Ds showed significant reductions in NAA/Cr and MI/Cr and a non-significant reduction in Cho/Cr in frontal lobes compared to ***,we observed significant decreases in NAA/Cr,MI/Cr,and Cho/Cr in the temporal and occipital lobes and basal ganglia in children with Ds compared to ***,there was a significant correlation between IQ and metabolic ratios in the brains of children with *** Brain metabolic profile could be a good predictor of IQ in children with Ds.

关键词： Children Down syndrome Magnetic resonance spectroscopy Metabolic profile Intelligence quotient

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A Typical Case of Classic Potter’s syndrome: A Case Report

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Open Journal of Pediatrics 2024年第3期14卷 482-487页

作者： Mohamed El Kerim Mahy mohammed Ech-Chebab Anass Ayyad sahar Messaoudi Rim Amrani Pediatrics/Residency Mohammed VI University Hospital Oujda Morocco Department of Neonatology and Neonatalintensive Care Unit Mohammed VI University Hospital Medical School University Mohammed 1st Oujda Morocco The Maternal-Child & Mental Health Research Laboratory Oujda Morocco

Potter syndrome is a rare congenital malformation that primarily affects male fetuses;it is characterized by pulmonary hypoplasia, skeletal malformation, and kidney abnormalities. The pressure of the uterine wall due to oligohydramnios leads to an unusual facial appearance, abnormal limbs in abnormal positions, or contractures. The fetus generally dies soon after birth due to respiratory insufficiency. The baby was a live preterm male, born to a 30-year-old multigravida, out of a non-consanguineous marriage via cesarean section. There was no liquor at the time of delivery. The baby did not cry immediately after birth and required resuscitation, followed by mechanical ventilation. Multiple congenital anomalies suggestive of Potter’s syndrome were noted including facial features, flattened nose, low protruding ear, retrognathism, and epicanthal folds with unilateral atresia of the choana. Chest X-ray showed small volume lung fields suggestive of pulmonary hypoplasia, and we had on ultrasonography bilateral polycystic kidney disease on ultrasonography. At 42 hours of life, the baby developed tachypnea and severe chest retractions and died due to respiratory insufficiency. Our case highlights the importance of regular prenatal checks and examinations in each pregnancy, which helps to collect suspected cases and improve knowledge of this syndrome for better management.

关键词： Potter syndrome Pulmonary Hypoplasia Potter’s Facies Polycystic Kidney Oligohydramnios

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Advancing Crowd Object Detection: A Review of YOLO, CNN and ViTs Hybrid Approach*

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Journal of Intelligent Learning systems and Applications 2024年第3期16卷 175-221页

作者： Mahmoud Atta mohammed Ali Tarek Aly Atef Tayh Raslan Mervat Gheith Essam A. Amin Faculty of Graduate studies for statistical Research Software Engineering Department Cairo University Giza Egypt

One of the most basic and difficult areas of computer vision and image understanding applications is still object detection. Deep neural network models and enhanced object representation have led to significant progress in object detection. This research investigates in greater detail how object detection has changed in the recent years in the deep learning age. We provide an overview of the literature on a range of cutting-edge object identification algorithms and the theoretical underpinnings of these techniques. Deep learning technologies are contributing to substantial innovations in the field of object detection. While Convolutional Neural Networks (CNN) have laid a solid foundation, new models such as You Only Look Once (YOLO) and Vision Transformers (ViTs) have expanded the possibilities even further by providing high accuracy and fast detection in a variety of settings. Even with these developments, integrating CNN, YOLO and ViTs, into a coherent framework still poses challenges with juggling computing demand, speed, and accuracy especially in dynamic contexts. Real-time processing in applications like surveillance and autonomous driving necessitates improvements that take use of each model type’s advantages. The goal of this work is to provide an object detection system that maximizes detection speed and accuracy while decreasing processing requirements by integrating YOLO, CNN, and ViTs. Improving real-time detection performance in changing weather and light exposure circumstances, as well as detecting small or partially obscured objects in crowded cities, are among the goals. We provide a hybrid architecture which leverages CNN for robust feature extraction, YOLO for rapid detection, and ViTs for remarkable global context capture via self-attention techniques. Using an innovative training regimen that prioritizes flexible learning rates and data augmentation procedures, the model is trained on an extensive dataset of urban settings. Compared to solo YOLO,

关键词： Object Detection Deep Learning Computer Vision YOLO Convolutional Neural Networks (CNN) Vision Transformers Neural Networks Transfer Learning Autonomous Driving self-Drive Vehicles

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Association of anxiety- depressive disorders with irritable bowel syndrome among patients attending a rural family practice center: a comparative cross- sectional study

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General Psychiatry 2021年第6期34卷 16-23页

作者： Alaa Adel mohammed heba Ahmed Moustafa hebatallah Nour-Eldein Rabab Atta saudi Family Medicine Department Suez Canal UniversityIsmailiaEgypt

Background Comorbidity of irritable bowel syndrome(IBs)and psychiatric disorders is common,and the prevalence of at least one psychiatric disorder has been reported as high as 80%among patients with *** To explore the association of anxiety-depressive disorders with IBs and its different subtypes,and to evaluate the associations of lifestyle habits,dietary habits and sleeping quality with *** A comparative cross-sectional study was conducted at the AL-Mahsama Family Practice Center,Ismailia,*** was carried out between October 2019 and October *** were categorised into 175 patients with IBs,diagnosed using the Rome IV criteria,and 175 patients without IBs.A semistructured questionnaire was used to collect data on sociodemographic characteristics,lifestyle habits,dietary habits and sleep quality from both *** Hamilton Anxiety Rating scale was used to assess anxiety symptoms,whereas the Beck Depression Inventory second Edition was used to assess depression *** There was a high statistically significant difference between both groups with regard to age,education,occupation and socioeconomic status(sEs),being a smoker,being physically inactive,having sleep disturbance and having irregular meals;being either obese or overweight was more reported in the IBs *** was a high statistically significant difference in the rate of anxiety and depression between patients with and without ***,moderate and severe anxiety were reported in 37.1%,42.9%and 20.0%of patients with IBs while most(80.0%)of the patients without IBs reported mild *** depression,mild,moderate and severe depression were reported in 60.0%,14.3%and 25.7%of the patients with IBs while most(82.9%)of the non-IBs participants reported mild *** The study shows a significant association between anxiety-depressive disorders and IBs,but no significant associations between anxiety-depressive disorders and IBs subtypes.

关键词： patients disorders sectional

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Automated Autism spectral Disorder Classification Using Optimal Machine Learning Model

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Computers, Materials & Continua 2023年第3期74卷 5251-5265页

作者： Hanan Abdullah Mengash Hamed Alqahtani mohammed Maray Mohamed K.Nour Radwa Marzouk mohammed Abdullah Al-Hagery heba Mohsen Mesfer Al Duhayyim Department of Information systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information systems College of Computer ScienceCenter of Artificial Intelligence and Unit of CybersecurityKing Khalid UniversityAbhaSaudi Arabia Department of Information systems College of Computer ScienceKing Khalid UniversityAbhaSaudi Arabia Department of Computer sciences College of Computing and Information SystemUmm Al-Qura UniversitySaudi Arabia Department of Computer science College of ComputerQassim UniversitySaudi Arabia Department of Computer science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt Department of Computer science College of Sciences and Humanities-AflajPrince Sattam bin Abdulaziz UniversitySaudi Arabia

Autism spectrum Disorder (AsD) refers to a neuro-disorder wherean individual has long-lasting effects on communication and interaction *** information technologywhich employs artificial intelligence(AI) model has assisted in early identify AsD by using pattern *** advances of AI models assist in the automated identification andclassification of AsD, which helps to reduce the severity of the *** study introduces an automated AsD classification using owl searchalgorithm with machine learning (AsDC-OsAML) model. The proposedAsDC-OsAML model majorly focuses on the identification and classificationof AsD. To attain this, the presentedAsDC-OsAML model follows minmaxnormalization approach as a pre-processing stage. Next, the owl searchalgorithm (OsA)-based feature selection (OsA-Fs) model is used to derivefeature subsets. Then, beetle swarm antenna search (BsAs) algorithm withIterative Dichotomiser 3 (ID3) classification method was implied for AsDdetection and classification. The design of BsAs algorithm helps to determinethe parameter values of the ID3 classifier. The performance analysis of theAsDC-OsAML model is performed using benchmark dataset. An extensivecomparison study highlighted the supremacy of the AsDC-OsAML modelover recent state of art approaches.

关键词： Autism spectral disorder machine learning owl search algorithm feature selection id3 classifier

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Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease

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Asian Pacific Journal of Tropical Biomedicine 2024年第5期14卷 207-214页

作者： Duaa M.Bakhshwin Foziya W.Alhalabi Mohamad Omar Barasheed Ahmed M.Bakhshwin Maha H.Jamal mohammed A.Bazuhair Fatemah O.Kamel Rania M.Magadmi Zoheir A Damanhouri samar M.Alsaggaf Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Hera General Hospital MakkahSaudi Arabia Department of Pathology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Clinical Anatomy Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To assess the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactose(D-GAL)-induced neurotoxicity in ***:Male Wistar rats were divided into 5 groups of 5 animals each:the positive control,the negative control,the memantine-treated group,the liraglutide-treated group,and the combination group treated with memantine and ***_(3)and D-GAL were used to induce *** tests,brain beta-amyloid protein,and oxidative stress biomarkers were ***:The Morris water maze test indicated an enhanced memory in the combination ***,the combination treatment of liraglutide and memantine resulted in a remarkable reduction in the beta-amyloid protein level in the brain *** inflammation and oxidative stress biomarkers were significantly reduced,and the levels of antioxidant parameters were ***:The combination of liraglutide and memantine exerts neuroprotective effects and enhances memory and cognitive functions in rats with Alzheimer’s disease.

关键词： Alzheimer’s disease Cognitive function Glucagonlike peptide-1 Liraglutide Memantine

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Coati Optimization-Based Energy Efficient Routing Protocol for Unmanned Aerial Vehicle Communication

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Computers, Materials & Continua 2023年第6期75卷 4805-4820页

作者： Hanan Abdullah Mengash Hamed Alqahtani mohammed Maray Mohamed K.Nour Radwa Marzouk mohammed Abdullah Al-Hagery heba Mohsen Mesfer Al Duhayyim Department of Information systems College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Information systems College of Computer ScienceCenter of Artificial Intelligence and Unit of CybersecurityKing Khalid UniversityAbha62529Saudi Arabia Department of Information systems College of Computer ScienceKing Khalid UniversityAbha62529Saudi Arabia Department of Computer sciences College of Computing and Information SystemsUmm Al-Qura UniversityMecca24382Saudi Arabia Department of Computer science College of ComputerQassim UniversityBuraydah52571Saudi Arabia Department of Computer science Faculty of Computers and Information TechnologyFuture University in EgyptNew Cairo11835Egypt Department of Computer science College of Sciences and Humanities-AflajPrince Sattam bin Abdulaziz UniversityAl-Kharj16278Saudi Arabia

With the flexible deployment and high mobility of Unmanned Aerial Vehicles(UAVs)in an open environment,they have generated con-siderable attention in military and civil applications intending to enable ubiquitous connectivity and foster agile *** difficulty stems from features other than mobile ad-hoc network(MANET),namely aerial mobility in three-dimensional space and often changing *** the UAV network,a single node serves as a forwarding,transmitting,and receiving node at the same ***,the communication path is multi-hop,and routing significantly affects the network’s performance.A lot of effort should be invested in performance analysis for selecting the optimum routing *** this motivation,this study modelled a new Coati Optimization Algorithm-based Energy-Efficient Routing Process for Unmanned Aerial Vehicle Communication(COAER-UAVC)*** presented COAER-UAVC technique establishes effective routes for communication between the *** is primarily based on the coati characteristics in nature:if attacking and hunting iguanas and escaping from ***,the presented COAER-UAVC technique concentrates on the design of fitness functions to minimize energy utilization and communication delay.A varied group of simulations was performed to depict the optimum performance of the COAER-UAVC *** experimental results verified that the COAER-UAVC technique had assured improved performance over other approaches.

关键词： Artificial intelligence unmanned aerial vehicle data communication routing protocol energy efficiency

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