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Prophet_TD Routing Algorithm Based on Historical Throughput and Encounter Duration

Computers, materials & Continua 2020年第9期64卷 1845-1858页

作者： Jingjian Chen Gang Xu Fengqi Wei Liqiang he College of Computer Science Inner Mongolia UniversityHuhehot010000China Geomechanica Inc. TorontoM5H 2Y2Canada

Opportunistic networks are self-organizing networks that do not require a complete path between the source node and the destination node as it uses encounter opportunities brought by nodes movement to achieve network *** networks routing algorithms are numerous and can be roughly divided into four categories based on different forwarding *** Prophet routing algorithm is an important routing algorithm in opportunistic *** forwards messages based on the encounter probability between nodes,and has good innovation significance and optimization ***,the Prophet routing algorithm does not consider the impact of the historical throughput of the node on message transmission,nor does it consider the impact of the encounter duration between nodes on message ***,to improve the transmission efficiency of opportunistic networks,this paper based on the Prophet routing algorithm,fuses the impact of the historical throughput of the node and the encounter duration between nodes on message transmission at the same time,and proposes the Prophet_TD routing algorithm based on the historical throughput and the encounter *** paper uses the Opportunistic Networks Environment v1.6.0(the ONE v1.6.0)as the simulation platform,controls the change of running time and the number of nodes respectively,conducts simulation experiments on the Prophet_TD routing *** simulation results show that compared to the traditional Prophet routing algorithm,on the whole,the Prophet_TD routing algorithm has a higher message delivery rate and a lower network overhead rate,and its average latency is also lower when node density is large.

关键词： Opportunistic networks encounter probability historical throughput encounter duration

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A Novel DT40 antibody Library for the Generation of monoclonal antibodies

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Virologica Sinica 2019年第6期34卷 641-647页

作者： Bei Wang Fei Wang he Huang Zhendong Zhao NHC Key Laboratory of Systems Biology of Pathogens Institute of Pathogen BiologyChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Clinical Immunology Center Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China CAmS-Oxford University International Center for Translational Immunology Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Early etiological diagnosis is very important for the control of sudden viral infections,and requires antibodies with both high sensitivity and high *** antibody preparation methods have limitations,such as a long and arduous cycle,complicated operation,and high expenses.A chicken lymphoma cell line,DT40,is known to produce Igm-type antibodies and undergo gene conversion and somatic mutation in the variable region of the immunoglobulin gene during ***,the DT40 cell line was developed to produce antibody libraries and prepare antibody rapidly in *** hypermutation in DT40 cells was regulated by the activation-induced cytidine deaminase(AID)gene,AID expression needs to be controlled to either fix the Ig sequence by stopping mutation or improve affinity by resuming mutation after the.antibodies have been *** this study,we generated a novel AID-inducible DT40 cell line(DT40-H7),in which the endogenous AID gene was knocked out using the CRISPR/Cas9 genome editing system,and an inducible AID gene,based on the Tet-Off expression system,was stably *** expression was controlled in DT40-H7 cells in a simple and efficient manner;gene conversion and point mutations were observed only when AID was *** the.antibody library generated from this cell line,we successfully obtained monoclonal antibodies against the NS1 protein of Zika *** DT40-H7 cell line represents a useful tool for the selection and evolution of antibodies and may also be a powerful tool for the rapid selection and generation of diagnostic antibodies for emerging infectious diseases.

关键词： antibody library DT40 cell line Activation-induced cytidine deaminase(AID) Zika virus(ZIKV)

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An Appraisal on Carmen m. Reinhart and Kenneth S. Rogoff (2011) From Financial Crash to Debt Crisis

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环球市场信息导报 2018年第6期 172-174页

作者： Jinyi he Yeting Zhu 安徽财经大学金融学院

This article is an appraisal on Reinhart and Rogoff (2011) from the perspectives of the topics addressed, the tools used and the contributions to the literature that is being claimed etc. in different topics discussed...

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A semiempirical algorithm for SAR wave height retrieval and its validation using Envisat ASAR wave mode data

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Acta Oceanologica Sinica 2012年第3期31卷 59-66页

作者： WANG he ZHU Jianhua YANG Jingsong SHI Chaoying National Ocean Technology Center State Oceanic AdministrationTianjin 300112China State Key Laboratory of Satellite Ocean Environment Dynamics Second Institute of OceanographyState Oceanic AdministrationHangzhou 310012China National Center of Ocean Standard and metrology State Oceanic AdministrationTianjin 300112China

many synthetic aperture radar (SAR) wave height retrieval algorithms have been ***,the wave height retrievals from most existing methods either depend on other input as the first guess or are restricted to the long wave regime.A semiempirical algorithm is presented,which has the objective to estimate the wave height from SAR imagery without any prior *** proposed novel algorithm was developed based on the theoretical SAR ocean wave imaging mechanism and the empirical relation between two types of wave *** dependency of the proposed model on radar incident and wave direction was *** Envisat advanced synthetic aperture radar (ASAR) wave mode data,the model can be reduced to the simple form with two input parameters,i.e.,the cutoff wavelength and peak wavelength of ocean wave,which can be retrieved from SAR imagery without any prior knowledge of wind or *** Envisat ASAR wave mode data and the collocated buoy measurements from NDBC,the scmicmpirical algorithm is validated and compared with the Envisat ASAR level 2 *** root-mean-square-error (RmSE) and scatter index (SI) in respect to the in situ measurements are 0.52 m and 19％ *** results indicate that,for Envisat ASAR wave mode data,the proposed method works well.

关键词： significant wave height SAR retrieval validation

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Carbonation Behavior Assessment of RH Slag Batch after Aqueous Extraction at Environmental Pressure

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Journal of Iron and Steel Research(International) 2014年第S1期21卷 74-81页

作者： An-jun XU Hui-ning ZHANG Dong-feng he State Key Laboratory of Advanced metallurgy University of Science and Technology Beijing School of metallurgical and Ecological Engineering University of Science and Technology Beijing School of metallurgy and Chemical Engineering Jiangxi University of Science and Technology

In order to assess CO2 sequestration amount and carbonation degree for RH slag at surrounding pressure, carbonation process of RH slag batch in lab is investigated, and the parameters of carbonation degree and CO2 sequestration amount are the targets, and the relationship between both and relevant factors, such as CO2 flow, gas bubble size etc. is originally discussed. The carbonation degree increases when temperature increases before 60 oC, then decreases. Particle size has a positive effect on carbonation degree, and carbonation degree for 0.5 L/min is bigger than those for 0.1 L/min and 1.0 L/min. When small gas bubble generator is adopted, carbonation degree and CO2 sequestration amount is improved. The maximum carbonation degree and CO2 sequestration amount is 34% and 178.65 g/kgslag, respectively when 38 μm RH slag batch is carbonated for 90 min at 60 oC under the conditions that CO2 flow is 0.5 L/min and bubble size equals 5 mm. CaCO3 and mgCO3 phases exists through XRD analysis, showing that carbonation process is effective. Carbonation degree model is established assuming carbonation reaction occurs on the active surface of RH slag batch. This model fits very well by comparison between experimental results and model results.

关键词： RH slag carbonation degree CO2 bubble size CO2 sequestration amount

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Evaluation of vehicle-track-bridge interacted system for the continuous CRTS-II non-ballast track slab

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Science China(Technological Sciences) 2014年第10期57卷 1895-1901页

作者： ZHANG Nan ZHOU Shuang XIA he SUN Lu School of Civil Engineering Beijing Jiaotong University School of Transportation Southeast University

Considering the CRTS-II track slab,which is commonly used in the Chinese high-speed railway system,a vehicle-track-bridge dynamic analysis method is proposed in which the vehicle subsystem equations are established by the rigid body dynamics method,the track subsystem and the bridge subsystem equations are established by the FEm,the wheel-rail contact relation is defined by the corresponding assumption in vertical direction and the Kalker linear creep theory in lateral *** in-span spring element is derived to model the track-bridge interaction;the equal-band-width storage is adopted to fit the track structure with multilayer uniform section beam;and the dynamic equilibrium equations are solved by the inter-history iteration *** a case study,the response of a CRH2 high-speed train transverses a simply-supported bridge with successive 31.5m double bound pre-stress beams is *** result shows that using the vehicle-track-bridge interaction model instead of the vehicle-bridge interaction model helps predict the rotation angle at beam ends and choose an economic beam vertical stiffness.

关键词：轨道板车辆道桥评价动体轮轨接触关系平衡方程相互作用模型

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Seismic Deformation and Seismic Resistance Analysis of Shapai Roller Compacted Concrete Arch Dam Based on Field monitoring and Dynamic Finite Element method

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山地科学学报（英文） 2013年第1期10卷 137-148页

作者： ZHUO Li he Jiang-da XIE Hong-qiang College of Water Resources and Hydroelectricity Sichuan University State Key Laboratory of Hydraulics and mountain River Engineering Sichuan University

Shapai Roller Compacted Concrete(RCC) Arch Dam is the highest RCC arch dam of the 20th century in the world with a maximum height of 132m,and it is the only concrete arch dam near the epicentre of Wenchuan earthquake on may 12th,*** seismic damage to the dam and the resistance of the dam has drawn great *** paper analyzed the response and resistance of the dam to the seismic wave using numerical simulations with comparison to the monitored *** field investigation after the earthquake and analysis of insitu data record showed that there was only little variation in the opening size at the dam and foundation interface,transverse joints and inducing joints before and after the *** overall stability of the dam abutment resistance body was quite good except a little relaxation was *** results of the dynamic finite element method(FEm) showed that the sizes of the openings obtained from the numerical modeling are comparable with the monitored values,and the change of the opening size is in millimeter *** study revealed that Shapai arch dam exhibited high seismic resistance and overload capacity in the Wenchuan earthquake *** comparison of the monitored and simulated results showed that the numerical method applied in this paper well simulated the seismic response of the *** method could be useful in the future application on the safety evaluation of RCC dams.

关键词：碾压混凝土拱坝动态有限元法现场监测地震变形抗震分析基础混凝土双曲拱坝三峡大坝

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Effect of Jinlong capsule on proliferation and apoptosis of human pancreatic cancer cells BxPC-3

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Journal of Traditional Chinese medicine 2013年第2期33卷 205-210页

作者： Yaoyuan Li Jieqing Hu Hui Huang Yonghe he Department of Oncology Guang'an men Hospital Affiliated to China Academy of Chinese Medical Sciences Department of Traditional Chinese medicine Fengtai District Community Health Center Jiansheng Pharmaceutical Co. Ltd.

OBJECTIVE:To study the possible roles of Jinlong capsule(JLC) on the proliferation and apoptosis of human pancreatic cancer cells ***:The human pancreatic cancer cells BxPC-3 were treated with JLC at the concentration of 0.05-1.00 mg/mL for 24-120 *** inhibition rate of JLC on human pancreatic cancer cells BxPC-3 was detected by 3-(4,5-dimethiylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(mTT) *** cytometry was employed to measure cell apoptosis using Annexin V-FITC/Propidium iodide(AV-FITC/PI) *** cycles were determined by PI *** expression of S100 Calcium binding protein A4(S100A4) in cell matrix was measured by enzyme-linked immunosorbent assay(ELISA).The expression levels of apoptosis-related protein such as BCL2/adenovirus E1B 19 kDa interacting protein 3(BNIP3),B-cell lymphoma/leukemia-2(Bcl-2) and Cys-teinylaspartate specific proteinase 3(Caspase-3) were detected byWestern ***:JLC significantly inhibited the proliferation of human pancreatic cancer cells BxPC-3 in a dose-dependent and time-dependent *** promoted cell apoptosis and maintained cell cycle in S and G 2 /m phase rather than G 1 /G 0 *** expression of S100A4 in the cell matrix was *** expression of cell apoptotic protein BNIP3 was increased while Bcl-2 was ***:JLC can inhibit the proliferation of human pancreatic cancer cells BxPC-3 by stimulating cell apoptosis,arresting the cell cycle at S and G 2 /m phase which blocks the circulation of normal cell cycle and reducing the expression of S100A4 *** pro-apoptosis protein BNIP3 and lower anti-apoptosis protein Bcl-2 levels were found,which may be related to the apoptotic effects of JLC.

关键词：细胞凋亡癌细胞胰腺增殖酶联免疫吸附试验胶囊 Western印迹钙结合蛋白

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Restoration of Eroded Thickness of the Neogene Strata in the Western Qaidam Basin and Its Significance for Oil and Gas Occurrence

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Acta Geologica Sinica(English Edition) 2017年第4期91卷 1352-1362页

作者： SUN Ping GUO Zeqing he Wenyuan LIU Weihong Advisory Center of CNPC Beijing 100724 China Langfang Branch Research Institute of Petroleum Exploration and Development CNPC Langfang 065007 Hebei China Institute of Geomechanics Chinese Academy of Geological Sciences Beijing 100081 China

During the Pleistocene, the western Qaidam Basin has largely experienced strong structural reconstruction and strong erosion. First, the eroded thickness of Neogene strata was restored approximately by the stratigraphic profile comparison method and plane trend surface restoring method; then, accurate calculation of erosion was recovered using vitrinite reflectance, and the erosion that was restored by the trend surface restoring method was corrected; finally, a distribution map of cumulative erosion was produced. This study marks an important achievement in that one of the most important parameters of basin tectonic evolution, sedimentary evolution, and oil and gas accumulation history has been obtained, and that a basic geological problem has been solved in the Qaidam Basin. The areas with high erosion and low erosion are shown in the map and a close relation between the distribution of oil and gas fields and erosion was recognized. Large and medium oil and gas fields are mainly distributed in areas with medium and low erosion. It is difficult to form large-scale oil and gas accumulation in areas in which erosion is more than 2000 m. The mechanism of the relation between oil and gas distribution and erosion is explained. This study will be of use in predicting the distribution of oil and gas.

关键词： western Qaidam Basin eroded thickness restoration method distribution characteristics,significance for oil and gas occurrence

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The change in thickness of the solidified liquid layer rather than the immobilized mass determines the frequency response of a quartz crystal microbalance

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Science China Chemistry 2012年第1期55卷 175-181页

作者： he JianAN LU YuDong FANG Jing mA HongWei Department of Biomedical Engineering College of EngineeringPeking UniversityBeijing 100871China Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of SciencesSuzhou 215123China Biomed-X Research Center Academy of Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China

The "solidified liquid layer" model has been examined using a quartz crystal microbalance(QCm) with a polymeric *** model is shown to give a reasonable explanation for the following experimental observations:(i) The opposite response of the QCm and surface plasmon resonance(SPR) for the activation process;(ii) the marked difference in the responses for IgG/anti-IgG interaction between QCm and *** analysis and experimental results indicated that QCm is sensitive to the thickness change of the "solidified liquid layer" but not the mass of captured biomolecules(i.e.,the immobilized mass),implying caution must be taken in interpreting QCm results.

关键词：石英晶体微天平分子质量厚度变化液体层频率响应凝固表面等离子体共振实验观察

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