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FAIR Guidelines and Data Regulatory Framework for Digital Health in Nigeria

Data Intelligence 2022年第4期4卷 839-851,1042-1043页

作者： Abdullahi Abubakar Kawu Joseph Elijah ibrahim Abdullahi Jamilu Yahaya Maipanuku Sakinat Folorunso Mariam Basajja Francisca Oladipo hauwa limanko ibrahim Department of Computer Science Ibrahim Badamasi Babangida University911101 LapaiNigeria Department of Mathematical Sciences Olabisi Onabanjo UniversityAgo-Iwoye120005 Ogun StateNigeria Leiden Institute of Computer Science 1011NCAmsterdamthe Netherlands Federal University 260101 LokojaNigeria Kampala International University Uganda

Adopting the FAIR Guidelines—that data should be Findable, Accessible, Interoperable and Reusable(FAIR)—in the health data system in Nigeria will help protect data against use by unauthorised parties, while also making data more accessible to legitimate users. However, little is known about the FAIR Guidelines and their compatibility with data and health laws and policies in Nigeria. This study assesses the governance framework for digital and health/e Health policies in Nigeria and explores the possibility of a policy window opening for the FAIR Guidelines to be adopted and implemented in Nigeria’s e Health sector. Ten Nigerian policy documents were examined for mention of the FAIR Guidelines(or FAIR Equivalent terminology) and the 15 sub-criteria or facets. The analysis found that although the FAIR Guidelines are not explicitly mentioned, 70% of the documents contain FAIR Equivalent terminology. The Nigeria Data Protection Regulation contained the most FAIR Equivalent principles(73%) and some of the remaining nine documents also contained some FAIR Equivalent principles(between 0–60%). Accordingly, it can be concluded that a policy window is open for the FAIR Guidelines to be adopted and implemented in Nigeria’s e Health sector.

关键词： FAIR Health data policy FAIR Equivalent terminology

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In vivo combination therapy of chloroquine and stigmasterol against Plasmodium berghei induced pathologies in mice

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Journal of Hainan Medical University 2020年第17期26卷 10-16页

作者： Auwal Adamu Muhammad A.Saliu Abdullahi A.Dantani Yaqub Nimat hauwa T.Giaze Najib Musa Buba Hussena Morik Dorathy Ahmad M.Kandi Musa Daniel Mohammed Auwal ibrahim Department of Biochemistry Ahmadu Bello UniversityZariaNigeria

Objective:To investigate the effect of combination therapy of chloroquine and stigmasterol on Plasmodium(P.)berghei malaria-induced organ ***:Totally 35 mice weighing 20-30g were placed into 7 groups of 5 mice each and distributed as uninfected administered 100 mg/kg BW stigmasterol,uninfected administered only feed and water ad libitum,infected with *** and administered 50 mg/Kg BW stigmasterol,100 mg/kg BW stigmasterol,100 mg/kg BW stigmasterol plus 5 mg/kg BW chloroquine,and 5 mg/kg BW *** last group of mice served as *** infected and not treated *** levels of parasitemia,packed cell volume,and other biochemical parameters were ***:Combination therapy of *** infection with stigmasterol and chloroquine did not significantly(P>0.05)reduce parasitemia level while stigmasterol treatment alone significantly(P0.05)altered upon treatment with both doses of stigmasterol as well as the combination ***:This study concluded that the combination of stigmasterol and chloroquine could combat anemia and some organ pathologies associated with *** infection.

关键词： Malaria Stigmasterol Chloroquine Plasmodium berghei Organ pathologies

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