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Ameliorating effect of Semecarpus anacardium *** milk extract on altered glucose metabolism in high fat diet STZ induced type 2 diabetic rats

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Asian Pacific Journal of Tropical Medicine 2012年第12期5卷 956-961页

作者： haseena banu hedayathullah khan Kaladevi Siddhi Vinayagam Shanthi Palanivelu Sachdanandam Panchanadham Department of Medical Biochemistry DR.A.L.M.P-G.I.B.M.S.University of MadrasTaramani CampusChennai-600113India

Objective:To explore the protective effect of the drug Semecarpus anacardium(***) on altered glucose metabolism in diabetic ***:Type 2 diabetes mellitus was induced by feeding rats with high fat diet followed by single intraperitoneal injection of streptozotocin (STZ)(35 mg/kg b.w.).Seven days after STZ induction,diabetic rats received nut milk extract of *** *** milk extract orally at a dosage of 200 mg/kg daily for 4 *** effect of nut milk extract of *** on blood glucose,plasma insulin,glucose metabolising enzymes and GSK were ***:Treatment with SA extract showed a significant reduction in blood glucose levels and increase in plasma insulin levels and also increase in HOMA-βand decrease in HOMA -*** drug significantly increased the activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase activity and increased the glycogen content in liver of diabetic rats while reducing the activities of gluconeogenic *** drug also effectively ameliorated the alterations in GSK-3 mRNA ***:Overall,the present study demonstrates the possible mechanism of glucose regulation of *** suggestive of its therapeutic potential for the management of diabetes mellitus.

关键词： Semecarpus anacardium Streptozotocin Carbohydrate metabolism Insulin signalling

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Towards Cache-Assisted Hierarchical Detection for Real-Time Health Data Monitoring in IoHT

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Computers, Materials & Continua 2023年第11期77卷 2529-2544页

作者： Muhammad Tahir Mingchu Li Irfan khan Salman AAl Qahtani Rubia Fatima Javed Ali khan Muhammad Shahid Anwar School of Software Technology Dalian University of Technology(DUT)Dalian116621China School of Software Technology Key Laboratory for Ubiquitous Network and Service Software of Liaoning ProvinceDalian116650China Department of Computer Engineering King Saud UniversityRiyadh11543Saudi Arabia School of Software Tsinghua UniversityBeijing100084China Department of Software Engineering University of Science and TechnologyBanu28100Pakistan Department of AI and Software Gachon UniversitySeongnamsi13120Korea

Real-time health data monitoring is pivotal for bolstering road services’safety,intelligence,and efficiency within the Internet of Health Things(IoHT)***,delays in data retrieval can markedly hinder the efficacy of big data awareness detection *** advocate for a collaborative caching approach involving edge devices and cloud networks to combat *** strategy is devised to streamline the data retrieval path,subsequently diminishing network *** an adept cache processing scheme poses its own set of challenges,especially given the transient nature of monitoring data and the imperative for swift data transmission,intertwined with resource allocation *** paper unveils a novel mobile healthcare solution that harnesses the power of our collaborative caching approach,facilitating nuanced health monitoring via edge *** system capitalizes on cloud computing for intricate health data analytics,especially in pinpointing health *** the dynamic locational shifts and possible connection disruptions,we have architected a hierarchical detection system,particularly during *** system caches data efficiently and incorporates a detection utility to assess data freshness and potential lag in response ***,we introduce the Cache-Assisted Real-Time Detection(CARD)model,crafted to optimize *** the inherent complexity of the NP-hard CARD model,we have championed a greedy algorithm as a *** reveal that our collaborative caching technique markedly elevates the Cache Hit Ratio(CHR)and data freshness,outshining its contemporaneous benchmark *** empirical results underscore the strength and efficiency of our innovative IoHT-based health monitoring *** encapsulate,this paper tackles the nuances of real-time health data monitoring in the IoHT landscape,presenting a joint edge-cloud caching strategy paired with a hierarchical detection *** methodology yields enh

关键词： Real-time health data monitoring Cache-Assisted Real-Time Detection(CARD) edge-cloud collaborative caching scheme hierarchical detection Internet of Health Things(IoHT)

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苯巴比妥和卡马西平应用于儿童期癫痫的副作用:随机对照研究

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英国医学杂志中文版 2007年第5期10卷 272-275页

作者： Selina H banu Moshrat Jahan Umme Kulsum Koli Saadia Ferdousi Naila Z khan Brian Neville 魏研萍 clinical neurophysiologist and paediatric neurologist primary care physician trained in childhood epilepsy child psychologist professor of child development and neurology Prince of Wales's professor of childhood epilepsy

目的比较两种最常用的抗癫痫药物——苯巴比妥和卡马西平在孟加拉儿童癫痫患者中应用时的行为学副作用。设计前瞻性随机对照单中心研究。地点孟加拉 Dhaka 儿童专科医院。对象 108例2～15岁全身性强直-阵挛发作(51例)或局限性继发全身... 详细信息

目的比较两种最常用的抗癫痫药物——苯巴比妥和卡马西平在孟加拉儿童癫痫患者中应用时的行为学副作用。设计前瞻性随机对照单中心研究。地点孟加拉 Dhaka 儿童专科医院。对象 108例2～15岁全身性强直-阵挛发作(51例)或局限性继发全身性发作(57例)的患儿。主要结局评估指标癫痫控制和行为学副作用。结果 91例患儿随访12个月。6例需改用其他抗癫痫药物。比较了85例患儿的药物副作用。药物治疗和随访1年,在随访中的后1/4时间,71例患儿未再癫痫发作。随机分组后,苯巴比妥组32例102天、卡马西平组39例74天未再癫痫发作。10例患儿行为学问题增多,其中4例不能接受(苯巴比妥组1例,卡马西平组3例)。但独立 t 检验显示,两组试验药物间没有显著性差异。结论在资源缺乏的国家,苯巴比妥不引起癫痫儿童过多的行为学副作用。临床试验注册号 NCT00381537[***]。

关键词：药物副作用随机对照研究儿童期癫痫苯巴比妥卡马西平强直一阵挛发作抗癫痫药物全身性发作

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