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Histological study of the structural layers around the esophagus in the lower mediastinum

World Journal of Gastrointestinal Surgery 2023年第7期15卷 1331-1339页

作者： Toshifumi saito Satoru Muro Hisashi Fujiwara Yuya Umebayashi Yuya Sato Masanori Tokunaga Keiichi Akita Yusuke Kinugasa Department of Gastrointestinal Surgery Tokyo Medical and Dental UniversityBunkyo-ku 113-8519TokyoJapan Department of Clinical Anatomy Tokyo Medical and Dental UniversityBunkyo-ku 113-8519TokyoJapan

BACKGROUND In Japan,the transhiatal approach,including lower mediastinal lymph node dissection,is widely performed for Siewert type II esophagogastric junction *** procedure is generally performed in a magnified view using laparoscopy or a robotic system,therefore,the microanatomy of the lower mediastinum is ***,mediastinal microanatomy is still unclear and classification of lower mediastinal lymph nodes is not currently based on fascia or other microanatomical *** To clarify the fascia and layer structures of the lower mediastinum and classify the lower mediastinal *** We dissected the esophagus and surrounding organs en-bloc from seven cadavers fixed in 10%*** and tissues were then cut at the level of the lower thoracic esophagus,embedded in paraffin,and serially *** sections were stained with Hematoxylin-Eosin(all cadavers)and immunostained for the lymphatic endothelial marker D2-40(three cadavers).We observed the periesophageal fasciae and layers,and defined lymph node boundaries based on the *** vessels around the esophagus were observed on immunostained tissue *** We identified two fasciae,A and *** then classified lower mediastinal tissue into three areas,paraesophageal,paraaortic,and intermediate,using these fasciae as *** nodes were found to be present and were counted in each *** dorsal part of the intermediate area was thicker on the caudal side than on the cranial side in all *** the dorsal side,no blood vessels penetrated the fasciae in six of the seven cadavers,whereas the proper esophageal artery penetrated fascia B in one cadaver.D2-40 immunostaining showed lymphatic vessel connections between the paraesophageal and intermediate areas on the lateral and ventral sides of the esophagus,but no lymphatic connection between areas on the dorsal side of the *** Histological studies identified two fasciae surroun

关键词： Esophagogastric junction Histology Mediastinum Adenocarcinoma Esophageal cancer Gastric cancer

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Distribution of splenic artery lymph nodes and splenic hilar lymph nodes

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World Journal of Gastrointestinal Surgery 2023年第5期15卷 812-824页

作者： Yuya Umebayashi Satoru Muro Masanori Tokunaga Toshifumi saito Yuya Sato Toshiro Tanioka Yusuke Kinugasa Keiichi Akita Department of Gastrointestinal Surgery Tokyo Medical and Dental UniversityTokyo 113-8519Japan Department of Clinical Anatomy Tokyo Medical and Dental UniversityTokyo 113-8519Japan

BACKGROUND Total gastrectomy with splenectomy is the standard treatment for advanced proximal gastric cancer with greater-curvature *** an alternative to splenectomy,laparoscopic spleen-preserving splenic hilar lymph node(LN)dissection(SPSHLD)has been *** SPSHLD,the posterior splenic hilar LNs are left *** To clarify the distribution of splenic hilar(No.10)and splenic artery(No.11p and 11d)LNs and to verify the possibility of omitting posterior LN dissection in laparoscopic SPSHLD from an anatomical *** Hematoxylin&eosin-stained specimens were prepared from six cadavers,and the distribution of LN No.10,11p,and 11d was *** addition,heatmaps were constructed and three-dimensional reconstructions were created to visualize the LN distribution for qualitative *** There was little difference in the number of No.10 LNs between the anterior and posterior *** LN No.11p and 11d,the anterior LNs were more numerous than the posterior LNs in all *** number of posterior LNs increased toward the hilar *** and three-dimensional reconstructions showed that LN No.11p was more abundant in the superficial area,while LN No.11d and 10 were more abundant in the deep intervascular *** The number of posterior LNs increased toward the hilum and was not ***,surgeons should consider that some posterior No.10 and No.11d LNs may remain after SPSHLD.

关键词： Gastric cancer Laparoscopic gastrectomy Anatomy Splenic hilar lymph node Laparoscopic spleen-preserving splenic hilar lymph node dissection

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On-line Free-viewpoint Video:From Single to Multiple View Rendering

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International Journal of Automation and computing 2008年第3期5卷 257-267页

作者： Vincent Nozick Hideo saito Graduate School of Science and Technology Keio University

In recent years, many image-based rendering techniques have advanced from static to dynamic scenes and thus become video-based rendering （VBR） methods. But actually, only a few of them can render new views on-line. We present a new VBR system that creates new views of a live dynamic scene. This system provides high quality images and does not require any background subtraction. Our method follows a plane-sweep approach and reaches real-time rendering using consumer graphic hardware, graphics processing unit （GPU）. Only one computer is used for both acquisition and rendering. The video stream acquisition is performed by at least 3 webcams. We propose an additional video stream management that extends the number of webcams to 10 or more. These considerations make our system low-cost and hence accessible for everyone. We also present an adaptation of our plane-sweep method to create simultaneously multiple views of the scene in real-time. Our system is especially designed for stereovision using autostereoscopic displays. The new views are computed from 4 webcams connected to a computer and are compressed in order to be transfered to a mobile phone. Using GPU programming, our method provides up to 16 images of the scene in real-time. The use of both GPU and CPU makes this method work on only one consumer grade computer.

关键词： Video-based rendering (VBR) free-viewpoint video view interpolation graphics processing unit (GPU) webcam stereovision autostereoscopic.

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Measurement of modulation induced by interaction between bubble motion and liquid-phase motion in the decaying turbulence formed by an oscillating-grid

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Particuology 2013年第2期11卷 158-169页

作者： Yasuyuki Nagami Takayuki saito Graduate School of Engineering Shizuoka University Graduate School of Science and Technology Shizuoka University

In multiphase flows, dynamical gas-liquid interactions are essential for in-depth understanding of their multi-scale phenomena and complicated structures. The purpose of the present study is to clearly extract the modulation in bubble motion and liquid motion induced by bubble-liquid interaction and to discuss the relations between bubble motion and liquid-phase motion. For this particular purpose, the decaying turbulence formed in a cylindrical acrylic pipe （diameter 149 mm, height 600 mm） by using an oscillating- grid was employed. Uniform single bubbles were launched from an in-house bubble launching device into the decaying turbulence. By comparing the bubble motion in the stagnant water with that in the oscillating-grid decaying turbulence, the transition of the 2D bubble motion （i.e., zigzagging motion） to 3D motion was enhanced in the latter. In addition, the initial conditions of the bubble motion that was not influenced by the ambient turbulence were carefully confirmed. In the area where the bubble motion started to translate from 2D motion into 3D motion, the modulation of ambient liquid-phase motion was obtained by PIV/LIF measurement. By combining these results, we quantitatively discussed the modulation of the bubble motion and ambient liquid-phase motion and considered the dominant factor for the enhancement to be the bubble-liquid interaction.

关键词： Multiphase flow Gas-liquid interaction Oscillating-grid decaying turbulence Bubble PIV/LIF LIF/HPTS

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Synthesis of a stroboscopic image from a hand-held camera sequence for a sports analysis

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Computational Visual Media 2016年第3期2卷 277-289页

作者： Kunihiro Hasegawa Hideo saito Keio University

This paper presents a method for synthesizing a stroboscopic image of a moving sports player from a hand-held camera sequence. This method has three steps: synthesis of background image,synthesis of stroboscopic image, and removal of player's shadow. In synthesis of background image step, all input frames masked a bounding box of the player are stitched together to generate a background image. The player is extracted by an HOG-based people *** synthesis of stroboscopic image step, the background image, the input frame, and a mask of the player synthesize a stroboscopic image. In removal of shadow step, we remove the player's shadow which negatively affects an analysis by using mean-shift. In our previous work, synthesis of background image has been timeconsuming. In this paper, by using the bounding box of the player detected by HOG and by subtracting the images for synthesizing a mask, computational speed and accuracy can be improved. These have contributed greatly to the improvement from the previous *** are main improvements and novelty points from our previous method. In experiments, we confirmed the effectiveness of the proposed method, measured the player's speed and stride length, and made a footprint image. The image sequence was captured under a simple condition that no other people were in the background and the person controlling the video camera was standing still, such like a motion parallax was not occurred. In addition, we applied the synthesis method to various scenes to confirm its versatility.

关键词： sports vision stroboscopic image stitching mask synthesis

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Gastric cancer incidence based on endoscopic Kyoto classification of gastritis

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世界胃肠病学杂志:英文版 2023年第31期29卷 4763-4773页

作者： Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Tatsuya Matsuno Gota Fujisawa Akira Toyoshima Hirotoshi Ebinuma Mitsuhiro Fujishiro Yutaka saito Hidekazu Suzuki Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalNarita 286-8520Japan Department of Colorectal Surgery Japanese Red Cross Medical CenterTokyo 150-8935Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Division of Endoscopy National Cancer Center HospitalTokyo 104-0045Japan Division of Gastroenterology and Hepatology Department of Internal MedicineTokai University School of MedicineIsehara 259-1193Japan

BACKGROUND Gastric cancer(GC)incidence based on the endoscopic Kyoto classification of gastritis has not been systematically investigated using time-to-event *** To examine GC incidence in an endoscopic surveillance *** This study was retrospectively conducted at the Toyoshima Endoscopy *** who underwent two or more esophagogastroduodenoscopies were *** incidence was based on Kyoto classification scores,such as atrophy,intestinal metaplasia(IM),enlarged folds(EFs),nodularity,diffuse redness(DR),and total Kyoto *** ratios(HRs)adjusted for age and sex were calculated using a Cox hazard *** A total of 6718 patients were enrolled(median age 54.0 years;men 44.2%).During the follow-up period(max 5.02 years;median 2.56 years),GC developed in 34 *** average frequency of GCs per year was 0.19%.Kyoto atrophy scores 1[HR with score 0 as reference:3.66,95%confidence interval(CI):1.06 to 12.61],2(11.60,3.82-35.27),IM score 2(9.92,4.37-22.54),EF score 1(4.03,1.63-9.96),DR scores 1(6.22,2.65-14.56),and 2(10.01,3.73-26.86)were associated with GC incidence,whereas nodularity scores were *** total Kyoto scores of 4(HR with total Kyoto scores 0-1 as reference:6.23,95%CI:1.93 to 20.13,P=0.002)and 5-8(16.45,6.29-43.03,P<0.001)were more likely to develop GC,whereas the total Kyoto scores 2-3 were *** HR of the total Kyoto score for developing GC per 1 rank was 1.75(95%CI:1.46 to 2.09,P<0.001).CONCLUSION A high total Kyoto score(≥4)was associated with GC *** endoscopy-based diagnosis of gastritis can stratify GC risk.

关键词： Gastric cancer Gastritis Endoscopy Atrophy Intestinal metaplasia Kyoto classification

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Miniaturization of Separation Systems and Its Applications

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色谱 2003年第6期21卷 638-648页

作者： Yoshihiro saito School of Materials Science

Development of miniaturized separation system consisted of microscale extraction and liquid phase separation processes has been reviewed. Various types of novel bonded stationary phases have been developed on the basis of the systematic analysis for the retention behavior of polycyclic aromatic hydrocarbons on experimentally synthesized *** this review,the miniaturization of microscale sample preparation technique and the effective on-line coupling to microcolumn liquid phase separations are also described especially focusing on the approach by the author’s *** novel use of synthetic polymer filaments as the stationary phase and extraction media in those microscale separation systems will be introduced along with the applications in gas chromatographic separation.

关键词：微型化分离系统应用微型柱在线耦合液相色谱法气相色谱

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日语流行语“壁ドン”的词汇化、语法化界面探析

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外语学刊 2022年第5期 52-58页

作者：王忻齐藤顺子浙江越秀外国语学院东语学院绍兴312000

“壁ドン”是影响力较大的日语流行语之一,其使用群体迅猛扩大,并出现跨语言现象,故对其分析极具意义。本文认为:该词由短语“手を壁にドンとつく”通过略写省略、重新分析等程序完成词汇化,在成词后的词内又发生词内成分的语法化,其后... 详细信息

“壁ドン”是影响力较大的日语流行语之一,其使用群体迅猛扩大,并出现跨语言现象,故对其分析极具意义。本文认为:该词由短语“手を壁にドンとつく”通过略写省略、重新分析等程序完成词汇化,在成词后的词内又发生词内成分的语法化,其后果是能产性爆发性增长,产生出聚合关系词群;其语法化发生在词汇化完成后的成词的“壁ドン”内部,表现为词内语素“~ドン”附着形式化即后缀化,主要证据为能产性爆发性增大;其词汇化与语法化的界面位于成词内部的“壁”与“ドン”之间。

关键词：日语流行语 “壁ドン” 词汇化语法化界面重新分析

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Application of DEM modified with enlarged particle model to simulation of bead motion in a bead mill

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Particuology 2014年第3期12卷 103-108页

作者： Yasuhiro Yamamoto Rikio Soda Junya Kano Fumio saito Mikuni Color Ltd. 101 KokubunjiMikunino-choHimejiHyogo 671-0234Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku University2-1-1 KatahiraAoba-kuSendai 980-8577Japan

We applied the discrete element method （DEM） of simulation modified by an enlarged particle model to simulate bead motion in a large bead mill. The stainless-steel bead mill has inner diameter of 102 mm and mill length of 198 mm. The bead diameter and filling ratio were fixed respectively at 0.5 mm and 85%. The agitator rotational speed was changed from 1863 to 3261 rpm. The bead motion was monitored experimentally using a high-speed video camera through a transparent mill body. For the simulation, enlarged particle sizes were set as 3-6 mm in diameter. With the DEM modified by the enlarged particle model, the motion of enlarged particles in a mill was *** velocity data of the simulated enlarged particles were compared with those obtained in the experiment. The simulated velocity of the enlarged particles depends on the virtual frictional coefficient in the DEM model. The optimized value of the virtual frictional coefficient can be determined by considering the accumulated mean value. Results show that the velocity of the enlarged particles simulated increases with an increase in the optimum virtual frictional coefficient, but the simulated velocity agrees well with that determined experimentally by optimizing the virtual frictional coefficient in the simulation. The computing time in the simulation decreases with increased particle size.

关键词： Discrete element simulation Bead mill Bead motion Enlarged particle model

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Dynamic pressure change in a rotating, laterally oscillating cylindrical container

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Journal of Ocean Engineering and Science 2018年第2期3卷 91-95页

作者： Yusuke saito Tatsuo Sawada Department of Mechanical Engineering Keio University3-14-1 HiyoshiKohoku-kuYokohama 223-8522Japan

We examined wave phenomena pertinent to water in a rotating,laterally oscillating cylindrical *** particular,we measured the time-dependent dynamic water pressure and pressure change by fast Fourier transform *** swirling of water in the container had three frequency components;the frequency responses of each frequency component are reported *** swirling occurs in a rotating cylindrical container,it was found that the wave rotating in the same direction as the rotation of the cylindrical container and the wave rotating in the opposite direction to the cylindrical container exist at the same *** swirling direction was determined by the relationship of these magnitude.

关键词： Sloshing Dynamic pressure Cylindrical container Rotation Oscillation Swirling

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