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Two-photon polymerization lithography for imaging optics

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International Journal of Extreme Manufacturing 2024年第4期6卷 21-60页

作者： hao Wang Cheng-Feng Pan Chi Li Kishan S Menghrajani Markus A Schmidt Aoling Li fu Fan Yu Zhou Wang zhang Hongtao Wang Parvathi Nair Suseela Nair John You En Chan Tomohiro Mori Yueqiang Hu Guangwei Hu Stefan A Maier haoran Ren Huigao Duan Joel K W Yang College of Mechanical and Vehicle Engineering Hunan UniversityChangsha 410082People's Republic of China Engineering Product Development Singapore University of Technology and DesignSingapore 487372Singapore Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300People's Republic of China Department of Electrical and Computer Engineering National University of Singapore4 Engineering Drive 3Singapore 117576Singapore School of Physics and Astronomy Faculty of ScienceMonash UniversityMelbourneVictoria 3800Australia Leibniz Institute of Photonic Technology 07745 JenaGermany Abbe Center of Photonics and Faculty of Physics FSU Jena07745 JenaGermany Otto Schott Institute of Material Research FSU Jena07745 JenaGermany Institute of Materials Research and Engineering A*STAR(Agency for Science Technology and Research)Singapore 138634Singapore Industrial Technology Center of Wakayama Prefecture Wakayama 6496261Japan School of Electrical and Electronic Engineering Nanyang Technological UniversitySingapore639798Singapore Department of Physics Imperial College LondonLondon SW72AZUnited Kingdom

Optical imaging systems have greatly extended human visual capabilities,enabling the observation and understanding of diverse *** technologies span a broad spectrum of wavelengths from x-ray to radio frequencies and impact research activities and our daily *** glass lenses are fabricated through a series of complex processes,while polymers offer versatility and ease of ***,modern applications often require complex lens assemblies,driving the need for miniaturization and advanced designs with micro-and nanoscale features to surpass the capabilities of traditional fabrication ***-dimensional(3D)printing,or additive manufacturing,presents a solution to these challenges with benefits of rapid prototyping,customized geometries,and efficient production,particularly suited for miniaturized optical imaging *** 3D printing methods have demonstrated advantages over traditional counterparts,yet challenges remain in achieving nanoscale ***-photon polymerization lithography(TPL),a nanoscale 3D printing technique,enables the fabrication of intricate structures beyond the optical diffraction limit via the nonlinear process of two-photon absorption within liquid *** offers unprecedented abilities,***-free fabrication,micro-and nanoscale capabilities,and rapid prototyping of almost arbitrary complex 3D *** this review,we emphasize the importance of the criteria for optical performance evaluation of imaging devices,discuss material properties relevant to TPL,fabrication techniques,and highlight the application of TPL in optical *** the first panoramic review on this topic,it will equip researchers with foundational knowledge and recent advancements of TPL for imaging optics,promoting a deeper understanding of the *** leveraging on its high-resolution capability,extensive material range,and true 3D processing,alongside advances in materials,fabrication,and design,we en

关键词： two-photon polymerization lithography 3D printing additive manufacturing imaging optics and nanophotonics

Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang Yong-hao Chen Jing-Yu Tang Rui-Rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-Xiang Chen Yi-Wei Yang Rong Liu Han Yi Yang Li Zhen Yang Qi An hao-Fan Bai Jiang-Bo Bai Jie Bao Ping Cao Qi-Ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-hao Gu Chang-Cai Han zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Wei-Hua Jia hao-yu Jiang Wei Jiang Zhi-jie Jiang Ling Kang Bo Li Chao Li Jia-Wen Li Xiao Li Jie Liu Shu-Bin Liu Guang-Yuan Luan Chang-Jun Ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song Kang Sun Zhi-Xin Tan Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Li-Kun Xie Yong-Ji Yu Guo-Hui zhang Lin-hao zhang Mo-Han zhang Qi-Wei zhang Xian-Peng zhang Yu-Liang zhang Yue zhang Zhi-Yong zhang Mao-Yuan Zhao Lu-Ping Zhou Zhi-hao Zhou Ke-Jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

Gamma/Hadron Separation Method for the HADAR Experiment

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Research in Astronomy and Astrophysics 2024年第3期24卷 70-74页

作者： Yang-Zhao Ren Tian-Lu Chen You-Liang Feng Dan-Zeng Luo-Bu Yi-Qing Guo Cheng Liu Qi Gao Mao-Yuan Liu Xiang-Li Qian Ya-Ping Wang zi-hao zhang Xin-Long Li Qing-Yuan Hou Heng-Jiao Liu Qing-Qian Zhou Shan-Jie Shu The Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences University of Chinese Academy of Sciences School of Intelligent Engineering Shandong Management University

Ground-based arrays of imaging atmospheric Cherenkov telescopes(IACTs)are the most sensitiveγ-ray detectors for energies of approximately 100 Ge V and *** such IACT is the High Altitude Detection of Astronomical Radiation(HADAR)experiment,which uses a large aperture refractive water lens system to capture atmospheric Cherenkov photons(i.e.,the imaging atmospheric Cherenkov technique).The telescope array has a low threshold energy and large field of view,and can continuously scan the area of the sky being observed,which is conducive to monitoring and promptly responding to transient *** process ofγ-hadron separation is essential in very-high-energy(>30 Ge V)γ-ray astronomy and is a key factor for the successful utilization of *** this study,Monte Carlo simulations were carried out to model the response of cosmic rays within the HADAR *** analyzing the Hillas parameters and the distance between the event core and the telescope,the distinction between air showers initiated byγ-rays and those initiated by cosmic rays was ***,a Quality Factor was introduced to assess the telescope’s ability to suppress the background and to provide a more effective characterization of its performance.

关键词： astroparticle physics-telescopes-methods data analysis

Ilizarov technique for treating elbow stiffness caused by myositis ossificans:A case report

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World Journal of Clinical Cases 2024年第17期12卷 3144-3150页

作者： Ming-Wang Zhou Peng-Wei zhang An-Le zhang Chang-hao Wei Yu-De Xu Wei Chen Zhi-Bin fu Department of Orthopedics Medicine Gansu Province Hospital of Chinese MedicineLanzhou 730050Gansu ProvinceChina Gansu University of Chinese Medicine Clinical College of Traditional Chinese MedicineLanzhou 730000Gansu ProvinceChina

BACKGROUND Myositis ossificans(MO)is a rare disease involving the formation of bone outside the musculoskeletal *** surgical intervention is the main treatment approach,preventing recurrence and standardized rehabilitation are also ***,we present a surgical strategy to prevent the recurrence of *** SUMMARY A 28-year-old female patient was admitted for the first time for a comminuted fracture of the left ***,incorrect postoperative rehabilitation resulted in the development of elbow joint stiffness with ectopic ossification,causing a loss of normal range of *** patient was diagnosed with MO based on physical examination,X-ray findings,and clinical *** devised a surgical strategy to remove MO,followed by fixation with an Ilizarov frame,and implemented a scientifically reasonable rehabilitation *** surgery lasted for 3 h with an estimated blood loss of 45 mL.A drainage tube was placed after surgery,and fluid was aspirated through ultrasound-guided *** patient experienced a significant reduction in joint stiffness after *** the final follow-up at 9 mouths,there was evident improvement in the range of motion of the elbow joint,and no other symptoms were *** The Ilizarov frame is an advantageous surgical technique for facilitating rehabilitation after MO *** offers benefits such as passive recovery,individualized treatment,and prompt recovery.

关键词： Myositis ossificans Ilizarov frame Rehabilitation strategy Stiffness Case report

Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1665-1674页

作者： Jie Xiong Shu Cheng Xiao Gao Shan-He Yu Yu-Ting Dai Xin-Yun Huang Hui-Juan Zhong Chao-fu Wang Hong-Mei Yi hao zhang Wei-Guo Cao Rong Li Wei Tang Yan Zhao Peng-Peng Xu Li Wang Wei-Li Zhao Shanghai Institute of Hematology State Key Laboratory of Medical GenomicsNational Research Center for Translational Medicine at ShanghaiRuijin Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghaiChina Department of Nuclear Medicine Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Pathology Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Otolaryngology Shanghai Rujin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Radiation Shanghai Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina Department of Hematology Navy Medical Center of PLAShanghaiChina Pole de Recherches Sino-Francais en Science du Vivant et Genomique Laboratory of Molecular PathologyShanghaiChina

Natural killer T cell lymphoma(NKTCL)is highly aggressive,with advanced stage patients poorly responding to intensive *** explore effective and safe treatment for newly diagnosed advanced stage NKTCL,we conducted a phase ll study of anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab(NCT04096690).Twenty-two patients with a median age of 51 years(range,24-74)were enrolled and treated with induction treatment of pegaspargase 2500 IU/m2 intramuscularly on day 1 and sintilimab 200 mg intravenously on day 2 for 6 cycles of 21 days,followed by maintenance treatment of sintilimab 200 mg for 28 cycles of 21 *** complete response and overall response rate after induction treatment were 59%(95%Cl,43-79%)and 68%(95%Cl,47-84%),*** a median follow-up of 30 months,the 2 year progression-free and overall survival rates were 68%(95%Cl,45-83%)and 86%(95%Cl,63-95%),*** most frequently grade 3/4 adverse events were neutropenia(32%,n=7)and hypofibrinogenemia(18%,n=4),which were manageable and led to no discontinuation of *** proportion score of PD-L1,peripheral blood high-density lipoprotein cholesterol,and apolipoprotein A-l correlated with good response,while PD-1 on tumor infiltrating lymphocytes and peripheral Treg cells with poor response to pegaspargase plus sintilimab *** conclusion,the chemo-free regimen pegaspargase plus sintilimab was effective and safe in newly diagnosed,advanced stage *** lipid profle and immunosuppressive signature contributed to treatment resistance,providing an alternative therapeutic approach dual targeting fatty acid metabolism and CTLA-4 in NKTCL.

关键词： killer metabolism lymphoma

反滤压重及埋深对深厚覆盖层允许坡降影响研究

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岩土力学 2024年第3期45卷 769-776页

作者：张会豪邱子源金伟张丹罗玉龙河海大学水利水电学院江苏南京210024 中国电建集团成都勘测设计研究院有限公司四川成都610072

反滤压重及埋深均会影响土体允许坡降,但目前尚无法量化这些影响。量化反滤压重及埋深的影响是合理确定允许坡降,科学评价坝基渗流安全的关键。采用轴向应力模拟反滤压重及埋深的作用,针对泸定水电站下游坝基(3)-1层,开展了(3)-1层级配... 详细信息

反滤压重及埋深均会影响土体允许坡降,但目前尚无法量化这些影响。量化反滤压重及埋深的影响是合理确定允许坡降,科学评价坝基渗流安全的关键。采用轴向应力模拟反滤压重及埋深的作用,针对泸定水电站下游坝基(3)-1层,开展了(3)-1层级配包络线在不同轴向应力条件下的渗透试验,量化了反滤压重及埋深对(3)-1层临界坡降的影响。结果表明:随着轴向应力的增大,(3)-1层上包线和平均线土体的临界坡降呈线性增加趋势,而下包线土体的临界坡降受轴向应力影响很小。基于试验结果,量化了反滤压重和埋深对(3)-1层允许坡降的贡献,建立了随轴向应力变化的(3)-1层土体允许坡降公式,提出了可考虑反滤压重措施及土体埋深影响的允许坡降建议取值方法,该方法可供后续类似工程借鉴采用。

关键词：深厚覆盖层允许坡降反滤压重埋深应力状态

All-sky Guide Star Catalog for CSST

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Research in Astronomy and Astrophysics 2024年第4期24卷 35-59页

作者： Hui-Mei Feng zi-Huang Cao Man I Lam Ran Li hao Tian Da-Yi Yin Yuan-Yu Yang Xin zhang Dong-Wei Fan Yi-Qiao Dong Xin-Feng Li Wei Wang Long Li Hugh RAJones Yi-Han Tao Jia-Lu Nie Pei-Pei Wang Mao-Yuan Liu He-jun Yang Chao Liu Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China University of ChineseAcademy of Sciences Beijing 100049China Shanghai Institute of Technical Physics Chinese Academy of SciencesShanghai200083China Technology and Engineering Center for Space Utilization.Chinese Academy of Sciences Beijing 100094China Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Centre for Astrophysics University of HertfordshireHatfieldUK Beijing University of Technology Beijing 100124China

The China Space Station Telescope(CSST)is a two-meter space telescope with multiple back-end *** Fine Guidance Sensor(FGS)is an essential subsystem of the CSST Precision Image Stability System to ensure the required absolute pointing accuracy and line-of-sight *** this study,we construct the Main Guide Star Catalog for *** accomplish this,we utilize the information about the FGS and object information from the Gaia Data Release *** provide an FGS instrument magnitude and exclude variables,binaries,and high proper motion stars from the catalog to ensure uniform FGS guidance ***,we generate a HEALPix index,which provides a hierarchical tessellation of the celestial sphere,and employ the Voronoi algorithm to achieve a homogeneous distribution of stars across the *** distribution ensures adequate coverage and sampling of the *** performance of the CSST guide star catalog was assessed by simulating the field of view of the FGS according to the CSST mock survey strategy *** analysis of the results indicates that this catalog provides adequate coverage and *** catalog's performance meets the FGS requirements,ensuring the functioning of the FGS and its guidance capabilities.

关键词： catalogs astrometry instrumentation:detectors

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小米各级蛋白组分对淀粉糊化特性的影响

中国食品学报 2024年第8期24卷 72-81页

作者：张凡付永霞曾鸣宋昊沈群北京一轻研究院有限公司北京101111 中国农业大学食品科学与营养工程学院北京100083 山西农业大学、山西功能食品研究院太原030024 北京北冰洋食品有限公司北京100162 北冰洋(北京)饮料食品有限公司北京100162

根据溶解度的不同,将4种蛋白组分从小米全粉体系中逐步去除,利用扫描电镜(SEM)、低场核磁共振(LF-NMR)、傅里叶变换红外光谱、快速黏度分析仪(RVA)探究样品结构及糊化特性的变化,并构建蛋白组分-淀粉重组体系进行反向验证。结果表明:整... 详细信息

根据溶解度的不同,将4种蛋白组分从小米全粉体系中逐步去除,利用扫描电镜(SEM)、低场核磁共振(LF-NMR)、傅里叶变换红外光谱、快速黏度分析仪(RVA)探究样品结构及糊化特性的变化,并构建蛋白组分-淀粉重组体系进行反向验证。结果表明:整体而言,醇溶蛋白对淀粉糊化特性的影响最为显著,其次为谷蛋白;清、球蛋白的影响程度较小。SEM结果显示,醇溶蛋白对复粒淀粉无连接、包裹作用,对淀粉糊化不构成物理屏障,而谷蛋白则明显包围连接了淀粉颗粒。结合蛋白组分特性及RVA、LF-NMR试验结果,可知醇溶蛋白的高疏水性引发了憎水效应,增加了体系内水分子移动性,促进淀粉颗粒吸水溶胀,提高淀粉各项糊化特性值;谷蛋白降低淀粉糊化的峰值黏度及崩解值,延长糊化峰值时间,限制糊化进程。

关键词：小米蛋白组分淀粉糊化特性

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基于贝叶斯神经网络的相位梯度计算方法

中国光学（中英文） 2024年第4期17卷 842-851页

作者：张康洋倪梓浩董博白玉磊广东工业大学自动化学院广东广州510006 智能检测与制造物联教育部重点实验室广东广州510006

应变重构是相衬光学相干层析力学性能表征中的关键步骤,其需要准确计算出差分包裹相位的梯度分布。为了能够解决强噪声干扰下的相位梯度重构信噪比低的难题,提出了一种基于贝叶斯神经网络的相位梯度计算方法。首先,通过计算机模拟不同... 详细信息

应变重构是相衬光学相干层析力学性能表征中的关键步骤,其需要准确计算出差分包裹相位的梯度分布。为了能够解决强噪声干扰下的相位梯度重构信噪比低的难题,提出了一种基于贝叶斯神经网络的相位梯度计算方法。首先,通过计算机模拟不同散斑噪声等级下的包裹相位图,并生成相应的理想相位梯度,以构建网络的训练集。其次,基于网络训练集采用贝叶斯推断理论学习强噪声环境下的包裹相位与相位梯度的“端到端”映射关系。最后,将相衬光学相干层析测量的差分包裹相位结果送入贝叶斯神经网络进行处理,实现高信噪比相位梯度预测。此外,通过借助贝叶斯神经网络的统计特性,以模型不确定度来定量评估相位梯度预测结果的可靠性。通过数值实验和三点弯曲力学加载实验对比分析了本文方法和主流矢量方法的性能。实验结果表明:在噪声较小的条件下,本文方法重构的相位梯度信噪比可提升8%;在噪声较强条件下,本文方法能成功恢复因相位条纹难以分辨而无法计算的相位梯度。此外,模型不确定度能够定量分析网络的相位梯度预测误差。可以预见,在样品形变复杂且先验信息未知的条件下,本工作为相衬光学相干层析提供了一种有效的应变重构方法,从而能实现高质量和高可靠的内部力学性能表征。

关键词：光学相干层析成像相衬技术相位梯度计算贝叶斯神经网络形变测量

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