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Modifiable risk factors for esophageal cancer in endoscopic screening population:A modeling study

Chinese Medical Journal 2024年第3期137卷 350-352页

作者： Qian Zhang Fan Wang hao Feng Jie Xing Shengtao zhu hao Zhang Yang Li Wenqiang Wei Shutian Zhang Department of Gastroenterology Beijing Friendship HospitalCapital Medical UniversityNational Clinical Research Center for Digestive DiseaseBeijing Digestive Disease CenterBeijing Key Laboratory for Precancerous Lesion of Digestive DiseaseBeijing 100050China Center for Applied Statistics and School of Statistics Renmin University of ChinaBeijing 100872China Statistical Consulting Center Renmin University of ChinaBeijing 100872China National Cancer Center National Clinical Research Center for CancerCancer InstituteChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Department of Gastroenterology Jizhong Energy Fengfeng Group HospitalHandanHebei 056000China RSS and China-Re Life Joint Lab on Public Health and Risk Management Renmin University of ChinaBeijing 100872China

To the Editor:Esophageal cancer,one of the most common cancer types in China,with an estimated 346,633 new cases and 323,600 deaths in 2022,is becoming an increasingly serious clinical and public health problem.^([1])The successful promotion of the self-management strategy has indicated that lifestyle modifications can be valuable in the primary prevention of cancer *** a healthy lifestyle has become a novel strategy for primary prevention and risk reduction in high-risk *** epidemiological studies have identified several lifestyle-related risk factors for esophageal cancer,including smoking and diet.^([2])Each factor can typically explain a modest proportion of cancer ***,when combined,these known risk factors may substantially affect the risk of esophageal ***,some risk factors for esophageal cancer are non-modifiable,including age,low socioeconomic status,and family *** and how these non-modifiable risk factors affect primary cancer prevention by intervening with modifiable risk factors remain unclear.

关键词： esophageal prevention promotion

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Direct ink writing of multifunctional gratings with gel-like MXene/norepinephrine ink for dynamic electromagnetic interference shielding and patterned Joule heating

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Nano Research 2024年第3期17卷 1585-1594页

作者： Pei-zhu Jiang Zhiming Deng Peng Min Lvxuan Ye Cheng-Zhang Qi hao-Yu Zhao Ji Liu hao-Bin Zhang Zhong-Zhen Yu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029China State Key Laboratory of Organic-Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China School of Chemistry CRANN and AMBERTrinity College DublinDublin D02PN40Ireland

Intelligent electromagnetic interference(EMI)shielding modulators with a wide tuning range and cyclic stability are urgently needed but their fabrication remains challenging.A gel-like MXene/norepinephrine ink is developed and multifunctional MXene gratings with wide EMI shielding effectiveness(SE)tuning range,superior reversibility,and high mechanical flexibility are constructed by direct ink writing approach for dynamic EMI shielding and patterned Joule heating *** modulable MXene/norepinephrine grating with a high conductivity of 3510 S·cm-1 can conveniently realize the seamless modulation of the EMI SE by adjusting the angle between the MXene grating filaments and the electric field of the incident electromagnetic waves,offering highly reversible switching between shielding“On”(28.0 dB)and“Off”(0.5 dB)***,due to the optimized integration of the MXene ink and the rationally designed pattern,a superior specific EMI SE of 95,688.2 dB·cm^(2)·g^(-1) is achieved in the“On”***,the MXene/norepinephrine ink can be used to fabricate many complex patterned gratings with superior stability,instant responsibility,and superb mechanical flexibility,exhibiting a unique patterned Joule heating *** writing of multifunctional gratings paves a means for developing intelligent EMI shielding materials,wearable electronic devices,and advanced thermal management materials.

关键词： MXene ink direct ink writing electromagnetic interference shielding multifunctional gratings Joule heating

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A thermodynamic view on the in-situ carbon dioxide reduction by biomass-derived hydrogen during calcium carbonate decomposition

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Chinese Journal of Chemical Engineering 2024年第4期68卷 231-240页

作者： Peng Jiang hao Zhang Guanhan Zhao Lin Li Tuo Ji Liwen Mu Xiaohua Lu Jiahua zhu State Key Laboratory of Materials-oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China

In the carbonate industry,deep decarbonization strategies are necessary to effectively remediate CO_(2).These strategies mainly include both sustainable energy supplies and the conversion of CO_(2)in downstream *** study developed a coupled process of biomass chemical looping H2 production and reductive calcination of CaCO_(3).Firstly,a mass and energy balance of the coupled process was established in Aspen *** this,process optimization and energy integration were implemented to provide optimized operation ***,a life cycle assessment was carried out to assess the carbon footprint of the coupled *** reveal that the decomposition temperature of CaCO_(3)in an H_(2)atmosphere can be reduced to 780℃(generally around 900℃),and the conversion of CO_(2)from CaCO_(3)decomposition reached 81.33%with an H2:CO ratio of 2.49 in gaseous *** optimizing systemic energy through heat integration,an energy efficiency of 86.30%was ***,the carbon footprint analysis revealed that the process with energy integration had a low global warming potential(GWP)of-2.624 kg·kg^(-1)(CO_(2)/CaO).Conclusively,this work performed a systematic analysis of introducing biomass-derived H_(2)into CaCO_(3)calcination and demonstrated the positive role of reductive calcination using green H_(2)in mitigating CO_(2)emissions within the carbonate industry.

关键词： Biomass CaCO_(3)reductive calcination Chemical looping Hydrogen production Carbon footprint Thermodynamics process

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A reduced combustion mechanism of ammonia/diesel optimized with multi-objective genetic algorithm

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Defence Technology（防务技术） 2024年第4期34卷 187-200页

作者： Wanchen Sun Shaodian Lin hao Zhang Liang Guo Wenpeng Zeng Genan zhu Mengqi Jiang State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130025China

For the deep understanding on combustion of ammonia/diesel,this study develops a reduced mechanism of ammonia/diesel with 227 species and 937 *** sub-mechanism on ammonia/interactions of N-based and C-based species(N—C)/NOx is optimized using the Non-dominated Sorting Genetic Algorithm II(NSGA-II)with 200 *** optimized mechanism(named as 937b)is validated against combustion characteristics of ammonia/methane(which is used to examine the accuracy of N—C interactions)and ammonia/diesel *** ignition delay times(IDTs),the laminar flame speeds and most of key intermediate species during the combustion of ammonia/methane blends can be accurately simulated by 937b under a wide range of *** for ammonia/diesel blends with various diesel energy fractions,reasonable predictions on the IDTs under pressures from 1.0 MPa to5.0 MPa as well as the laminar flame speeds are also achieved by *** particular,with regard to the IDT simulations of ammonia/diesel blends,937b makes progress in both aspects of overall accuracy and computational efficiency,compared to a detailed ammonia/diesel *** kinetic analysis reveals that the reaction pathway of ammonia during the combustion of ammonia/diesel blend mainly differs in the tendencies of oxygen additions to NH_2 and NH with different equivalence ratios.

关键词： Ammonia Diesel Combustion Kinetic mechanism Multi-objective optimization

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Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer’s Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice

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Neuroscience Bulletin 2024年第2期40卷 182-200页

作者： Yang zhu hao Huang Zhi Chen Yong Tao Ling-Yi Liao Shi-hao Gao Yan-Jiang Wang Chang-Yue Gao Department of Rehabilitation Medicine Daping HospitalArmy Medical UniversityChongqing 400042China Department of Neurology and Center for Clinical Neuroscience Daping HospitalArmy Medical UniversityChongqing 400042China Department of Special Medicine Daping HospitalArmy Medical UniversityChongqing 400042China

Intermittent theta burst stimulation(iTBS),a time-saving and cost-effective repetitive transcranial magnetic stimulation regime,has been shown to improve cognition in patients with Alzheimer’s disease(AD).However,the specific mechanism underlying iTBS-induced cognitive enhancement remains *** studies suggested that mitochondrial functions are modulated by magnetic ***,we showed that iTBS upregulates the expression of iron-sulfur cluster assembly 1(ISCA1,an essential regulatory factor for mitochondrial respiration)in the brain of APP/PS1 *** vivo and in vitro studies revealed that iTBS modulates mitochondrial iron-sulfur cluster assembly to facilitate mitochondrial respiration and function,which is required for ***,iTBS rescues cognitive decline and attenuates AD-type pathologies in APP/PS1 *** present study uncovers a novel mechanism by which iTBS modulates mitochondrial respiration and function via ISCA1-mediated iron-sulfur cluster assembly to alleviate cognitive impairments and pathologies in *** provide the mechanistic target of iTBS that warrants its therapeutic potential for AD patients.

关键词： Intermittent theta burst stimulation Alzheimer’s disease Iron-sulfur cluster assembly 1 Mitochondrial dysfunction Neurodegeneration

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Differential expression of miRNAs and mRNAs in the livers of largemouth bass Micropterus salmoides under heat stress

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Journal of Oceanology and Limnology 2024年第2期42卷 594-608页

作者： Xuqian Zhao Zijie LIN Caijuan LI hao zhu Lingling LI Wenjia MAO Qufei LING School of Biology and Basic Medical Sciences Suzhou Medical College of Soochow UniversitySuzhou 215000China

Global warming threatens freshwater ecosystems and compromises fish *** elucidate the role of miRNAs in the livers of heat stressed largemouth bass,juvenile fish was subject to heat stress under 37°*** mRNA-seq and miRNA-seq were conducted on the liver tissues under control and heat stress *** gene expression analysis and enrichment analysis were performed on mRNA and miRNA expression profiles.A total of 406 differentially expressed genes(DEGs)were discovered,of which 212 were up-regulated and 194 were *** of the DEGs were significantly implicated in the regulation of“protein processing in endoplasmic reticulum”,“proteasome”,“steroid biosynthesis”,and“ornithine decarboxylase inhibitor activity”*** addition,47 differentially expressed miRNAs(DEMs)were identified in largemouth bass livers under heat stress,including 21 up-regulated and 25 down-regulated miRNAs.A negatively regulated miRNA-mRNA network including 12 miRNAs and 19 mRNAs was constructed with DEMs involved in“protein degradation”,“calcium ion regulation”,“cell apoptosis”,and“lipid metabolism”.Moreover,this study indicated novel-miR-144 activated the IRE1 signaling pathway by targeting txndc5 to induce liver apoptosis in largemouth bass under heat *** study revealed the involvement of miRNA regulation in largemouth bass in response to heat stress.

关键词： heat stress largemouth bass miRNA-mRNA interaction

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Synergetic optimization operation method for distribution network based on SOP and PV

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Global Energy Interconnection 2024年第2期7卷 130-141页

作者： Lei Chen Ning Zhang Xingfang Yang Wei Pei Zhenxing Zhao Yinan zhu hao Xiao State Grid Shijiazhuang Electric Power Company Shijiazhuang 130100P.R.China Institute of Electrical Engineering Chinese Academy of SciencesBeijing 100190P.R.China IEEE Power and Energy Society New YorkUSA

The integration of distributed generation brings in new challenges for the operation of distribution networks,including out-of-limit voltage and power flow *** open points(SOP)are new power electronic devices that can flexibly control active and reactive power *** the exception of active power output,photovoltaic(PV)devices can provide reactive power compensation through an ***,a synergetic optimization operation method for SOP and PV in a distribution network is proposed.A synergetic optimization model was *** voltage deviation,network loss,and ratio of photovoltaic abandonment were selected as the objective *** PV model was improved by considering the three reactive power output modes of the PV *** the load fluctuation and loss of the SOP were *** multi-objective optimization algorithms were used,and a compromise optimal solution was *** studies were conducted using an IEEE 33-node *** simulation results indicated that the SOP and PVs complemented each other in terms of active power transmission and reactive power *** optimization improves power control capability and flexibility,providing better power quality and PV consumption rate.

关键词： Synergetic optimization Soft open point(SOP) Photovoltaic(PV) Distribution network

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Towards carbon neutrality of calcium carbide-based acetylene production with sustainable biomass resources

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Green Energy & Environment 2024年第6期9卷 1068-1078页

作者： Peng Jiang Guanhan Zhao hao Zhang Tuo Ji Liwen Mu Xiaohua Lu Jiahua zhu State Key Laboratory of Materials-oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing211816China

Acetylene is produced from the reaction between calcium carbide(CaC_(2))and water,while the production of CaC_(2) generates significant amount of carbon dioxide not only because it is an energy-intensive process but also the raw material for CaC_(2) synthesis is from ***,a comprehensive biomass-to-acetylene process was constructed that integrated several units including biomass pyrolysis,oxygen-thermal CaC_(2) fabrication and calcium *** comparison,a coal-to-acetylene process was also established by using coal as *** carbon efficiency,energy efficiency and environmental impacts of the bio-based calcium carbide acetylene(BCCA)and coal-based calcium carbide acetylene(CCCA)processes were systematically ***,the environmental impacts were further evaluated by applying thermal integration at system level and energy substitution in CaC_(2) *** though the BCCA process showed lower carbon efficiency and energy efficiency than that of the CCCA process,life cycle assessment demonstrated the BCCA(1.873 kgCO_(2eq) kg-prod^(-1))a lower carbon footprint process which is 0.366 kgCO_(2eq) kg-prod^(-1) lower compared to the CCCA *** sustainable energy(biomass power)substitution in CaC_(2) furnace,an even lower GWP value of 1.377 kgCO_(2eq) kg-prod^(-1) can be achieved in BCCA *** work performed a systematic analysis on integrating biomass into industrial acetylene production,and revealed the positive role of biomass as raw material(carbon)and energy supplier.

关键词： Biomass pyrolysis CO_(2)mitigation Calcium carbide Acetylene Calcium loop

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Petroleum pitch derived hard carbon via NaCl-template as anode materials with high rate performance for sodium ion battery

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Frontiers of Chemical Science and Engineering 2024年第7期18卷 1-10页

作者： Baoyu Wu hao Sun Xiaoxue Li Yinyi Gao Tianzeng Bao Hongbin Wu Kai zhu Dianxue Cao Key Laboratory of Superlight Materials and Surface Technology of Ministry of Education College of Materials Science and Chemical EngineeringHarbin Engineering UniversityHarbin 150001China Hunan Hongshan New Energy Technology Co. LtdYiyang 413000China

Sodium-ion batteries(SIBs)have garnered significant interest in energy storage due to their similar working mechanism to lithium ion batteries and abundant reserves of sodium *** facile synthesis of a carbon-based anode materials with capable electrochemical performance is key to promoting the practical application of *** this work,a combination of petroleum pitch and recyclable sodium chloride is selected as the carbon source and template to obtain hard carbon(HC)anode for *** times and temperatures are optimized by assessing the sodium ion storage behavior of different HC *** optimized HC exhibits a remarkable capacity of over 430 mAh·g^(-1) after undergoing full activation through 500 cycles at a density of current of 0.1 A·g^(-1).Furthermore,it demonstrates an initial discharge capacity of 276 mAh·g^(-1) at a density of current of 0.5 A·g^(-1).Meanwhile,the optimized HC shows a good capacity retention(170 mAh·g^(-1) after 750 cycles)and a remarkable rate ability(166 mAh·g^(-1) at 2 A·g^(-1)).The enhanced capacity is attributed to the suitable degree of graphitization and surface area,which improve the sodium ion transport and storage.

关键词： petroleum pitch hard carbon sodium-ion batteries high rate recyclable template

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Preparation of vanadium-based electrode materials and their research progress in solid-state flexible supercapacitors

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Rare Metals 2024年第2期43卷 431-454页

作者： Rui-Jie zhu Jiang Liu Chao Hua hao-Yu Pan Yi-Jun Cao Meng Li Zhongyuan Critical Metals Laboratory Zhengzhou UniversityZhengzhou450001China School of Chemical Engineering Zhengzhou UniversityZhengzhou450001China

Solid-state flexible supercapacitors(SCs)have many advantages of high specific capacitance,excellent flexibility,fast charging and discharging,high power density,environmental friendliness,high safety,light weight,ductility,and long cycle *** are the ideal choice for the development of flexible energy storage technology in the future,and provide a good prospect for energy storage *** present,solid-state flexible SCs are widely used for portable electronic equipment and wearable energy storage equipment,the research of them has become the focus of a growing number of *** material is the key part of SCs and always determines the electrochemical performance of *** has been a hotspot and focus of ***-based compounds are considered to be a promising electrode material for SCs because of variable valence,open structure,high theoretical capacity,and low ***,this study first gives an overview of solid-state flexible SCs,then reviews the current research status of vanadium-based electrode materials in solid-state flexible SCs,and proposes some strategies to solve some problems of vanadium-based electrode materials.

关键词： Vanadium-based materials Flexible energy storage Specific capacitance Supercapacitors(SCs)

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