检索结果-南通市图书馆

Dynamical analysis of a diffusive malaria model with fixed latent period in the human and vector populations

在线全文

学校读者我要写书评

暂无评论

International Journal of Biomathematics 2023年第1期16卷 209-234页

作者： hao qu Tianli Jiang Jinliang Wang Jiantao Zhao School of Mathematical Science Heilongjiang University Harbin 150080P.R.China

To investigate the impact of the fixed latent periods in the human and vector populations on the disease transmission in heterogenous environment,we formulate a nonlocal and time-delayed reaction-diffusion(NLTD-RD)*** appealing to the next generation operator(NGO),we define the basic reproduction number(BRN)Ro,and prove it as a threshold parameter for indicating whether disease persists or ***,if oquilibrium is globally asymptotically stable,while if Ro>1,the disease is shown to be uniformly *** the homogeneous case that all parameters are assumed to be constants,the explicit expression of o is *** further achieved the global attractivity of the constant equilibria by utilizing Lyapunov *** simulations are performed to verify the theoretical results and the effects of the diffusion rate on disease transmission.

关键词： Nonlocal delays spatial heterogeneity basic reproduction number uniform persistence Lyapunov functionals

Real-time detection of Cu(Ⅱ)with PEDOT:PSS based organic electrochemical transistors

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2017年第9期60卷 1205-1211页

作者： Can Xiong hao qu Wei Chen Lijun Zhang Longzhen Qiu Lei Zheng Fan Xia School of Food Science and Engineering Hefei University of TechnologyHefei 230009China School of Biological and Medical Engineering Hefei University of TechnologyHefei 230009China Academy of Opto-Electronic Technology Hefei University of TechnologyHefei 230009China School of Chemistry and Chemical Engineering Huazhong University of Science and TechnologyWuhan 430074China

Copper is an essential element in the environment and the human body, but at the same time, exposure to high concentrations of Cu2+ions will potentially lead to acute toxicity and various neurodegenerative diseases. Thus, it is of great significance for the development of highly sensitive and selective strategies for the detection of Cu2+ions. Here, we report a highly efficient poly(3,4-ethylenedioxythiophene):poly(styrene sulfonic acid) (PEDOT:PSS) based organic electrochemical transistor (OECT) sensor, for real-time Cu2+ions detection. The detection limit of the OECT device is as low as 100 nM, far beyond the sensitivity required for practical uses. The detection mechanism may base on the chemical reactivity of Cu2+ions oxiding the PEDOT:PSS in solution both in absence and presence of the base potential. The OECT devices also exhibit excellent selective response to Cu2+ions rather than other metal ions. Finally, we also demonstrate the determination of Cu2+ions in tap water with the OECT Cu2+sensor. Considering the high sensitivity and selectivity, as well as the real-time and low cost features of our Cu2+OECT sensor, it is ideal for portable and disposable applications for environment monitoring and public health. © 2017, Science China Press and Springer-Verlag Berlin Heidelberg.

关键词： Chemical detection Conductive plastics Copper Metal ions Metals Neurodegenerative diseases Public health Signal detection Styrene

Investigation on small molecule-aptamer dissociation equilibria based on antisense displacement probe

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2023年第4期12卷 1257-1264页

作者： Lei Wang Lili Yao Qihui Ma Yu Mao hao qu Lei Zheng School of Food and Biological Engineering Hefei University of TechnologyHefei 230009China

Food safety is a major issue to public health and have attracted global ***,sensitive,and reliable detection methods for food hazardous substances is highly *** which can bind to the target molecules with high affinity and specificity represent an attractive tool for the recognition of food hazardous substances,which play an important role in the development and application of new food safety detection *** current assays for characterizing small molecule-aptamer binding are limited by either the mass sensitivity or the size differentiation ***,we proposed a comprehensive method for assessing the dissociation equilibria of small molecule-aptamer,which is immobilized-free under ambient *** design employs the Le Chatelier’s principle and could be used to effectively measure small molecule-aptamer *** binding aptamer and anti-aflatoxin B1 aptamer were used as the model system to determine their affinity,in which their dissociation equilibria measurements are in excellent close to their previous *** to the simplicity and sensitivity of this new method,we believe that it could be recommended as an effective tool for characterizing small molecule-aptamer interactions and promote the further application of small molecular aptamer in food safety.

关键词： Aptamer Small molecule Dissociation equilibria Antisense displacement probe Le Chatelier’s principle

Growth and physiological responses of Agriophyllum squarrosum to sand burial stress

在线全文

学校读者我要写书评

暂无评论

Journal of Arid Land 2015年第1期7卷 94-100页

作者： Jin LI hao qu HaLin Zhao RuiLian ZHOU JianYing YUN ChengChen PAN Cold and Arid Regions Environmental and Engineering Institute Chinese Academy of Sciences Faculty of Life Sciences Ludong University

Agriophyllum squarrosum is an annual desert plant widely distributed on mobile and semi-mobile dunes in all the sandy deserts of China. We studied the growth and physiological properties of A. squarrosum seedlings under different sand burial depths in 2010 and 2011 at Horqin Sandy Land, Inner Mongolia to understand the ability and mechanism that A. squarrosum withstands sand burial. The results showed that A. squarrosum had a strong ability to withstand sand burial. Its survival rate, plant height and biomass increased significantly at a burial depth 25% of seedling height and decreased significantly only when the burial depth exceeded the height of the seedlings; some plants still survived even if the burial depth reached 266% of a seedling height. The malondialdehyde （MDA） content and membrane permeability of the plant did not change significantly as long as the burial depth was not greater than the seedling height; lipid peroxidation increased and cell membranes were damaged if the burial depth was increased further. When subjected to sand burial stress, superoxide dismutase （SOD） and peroxidase （POD） activities and free proline content increased in the seedlings, while the catalase （CAT） activity and soluble sugar content decreased. Sand burial did not lead to water stress. Reductions in photosynthetic area and cell membrane damage caused by sand burial may be the major mechanisms increasing mortality and inhibiting growth of the seedling. But the increases in SOD and POD activities and proline content must play a certain role in reducing sand burial damage.

关键词： Agriophyllum squarrosum psammophyte sand burial stress growth inhibition physiological response

Successful diagnosis and treatment of jejunal diverticular haemorrhage by full-thickness enterotomy: A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第19期9卷 5232-5237页

作者： Hua-Chong Ma Hui Xiao hao qu Zhen-Jun Wang Department of General Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China

BACKGROUND Jejunal diverticula are the rarest of all small bowel diverticula and usually have no classic clinical *** diverticular haemorrhage(JDH)is a rare complication and can be difficult to identify and manage,hence it always resulting in a diagnostic delay and unsatisfactory clinical *** with the advances in endoscopic technology,no consensus have been reached on the diagnosis and management of JDH,the conventional surgical intervention still remains the mainstream for the management of *** report an unique case of a 63-year-old male who presented with massive haemorrhage from jejunal diverticula,which was successfully managed by initial resuscitation and definitive *** SUMMARY A 63-year-old male was admitted as an emergency with 6 h history of haematemesis and *** haematemesis appeared to be bright red,with volume exceeding 100 *** amount of melena was estimated to be 200 ***,the patient received fluid resuscitation and three unit blood ***,in order to localize the bleeding sites,colonoscopy,upper gastrointestinal endoscopy,and mesenteric angiography were utilized but failed to identify the source of *** consent form was obtained for further treatment,and he was treated with an exploratory laparotomy and the bleeding site was successfully located during the *** was diagnosed with *** postoperative period was uneventful,and he was discharged on day 18 after *** rebleeding occurred at the 1-year *** In patients with gastrointestinal bleeding,if various techniques fail to identify the cause of haemorrhage in small bowel and haemodynamic instability is sustained with continuous resuscitation,we recommend surgical intervention should be the ultimate treatment of choice.

关键词： Case report Jejunal diverticular haemorrhage Colonoscopy Gastrointestinal bleeding Surgical intervention

Variation in soil water content to rainfall under Caragana microphylla shrub in Horqin Sandy Land

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Arid Land 2010年第3期2卷 174-179页

作者： Wang, ShaoKun Zhao, XueYong qu, hao Luo, YaYong Yun, JianYing Chinese Acad Sci Naiman Desertificat Res Stn Cold & Arid Reg Environm & Engn Res Inst Lanzhou 730000 Peoples R China Chinese Acad Sci Grad Univ Beijing 100039 Peoples R China

In order to investigate the spatio-temporal variability of soil water content to rainfall under Caragana microphylla shrub in Horqin Sandy Land,a plot of 25 m × 25 m,where there were 6 shrub canopies of C. microphylla,was sited for measuring soil water content at two soil layers of 0-20 cm (top layer) and 20-40 cm (lower layer). Soil water content was measured on the 1st,5th,10th and 15th day after a 42 mm rainfall in Naiman of Inner Mongolia. The results showed that soil water contents at both layers under C. microphylla shrub were gradually decreased after the rain. Soil water content at the top layer outside the shrub canopy was higher than that inside the shrub canopy within 5 days,and became similar inside and outside the shrub canopy on the 10th day after the 42 mm rainfall,and it was lower outside than that inside the shrub canopy on the 15th day. The soil water content at lower layer in the area without shrubs was higher than that under shrub canopy all along. All the measured values of soil water content can be fitted to a variogram model. There was significant autocorrelation of the values of soil water content between top layer and lower layer,except for the fourth measured values of soil water content at top layer. The range and spatial dependence of soil water content at top layer were lower than that at lower layer.

关键词： Horqin Sandy Land Caragana microphylla soil water content spatial variability

Traditional Chinese medicine in the treatment of Helicobacter pylorirelated gastritis:The mechanisms of signalling pathway regulations

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第3期31卷 11-28页

作者： Pei-Pei Zhang Liang Li hao-Yu qu Guang-Yu Chen Meng-Zhou Xie Yan-Kun Chen School of Traditional Chinese Medicine Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Hunan Engineering Technology Research Center for Medicinal and Functional Food Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina Key Laboratory of Traditional Chinese Medicine Heart and Lung Syndrome Differentiation and Medicated Diet and Dietotherapy Hunan University of Chinese MedicineChangsha 410200Hunan ProvinceChina School of Informatics Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Precision Medicine Research and Development Center Zhuhai Institute of Advanced TechnologyChinese Academy of SciencesZhuhai 519000Guangdong ProvinceChina

Helicobacter pylori-associated gastritis(HPAG)is a common condition of the gastrointestinal ***,extensive and long-term antibiotic use has resulted in numerous adverse effects,including increased resistance,gastrointestinal dysfunction,and increased recurrence *** these concerns develop,traditional Chinese medicine(TCM)may have *** is based on the concept of completeness and aims to eliminate pathogens and strengthen the *** has the potential to prevent this condition while also boosting the rate of Helicobacter pylori *** review elaborates on the mechanism of TCM treatment for HPAG based on cellular signalling pathways,which reflects the flexibility of TCM in treating diseases and the advantages of multi-level,multipathway,and multi-target treatments for HPAG.

关键词： Helicobacter pylori Helicobacter pylori-associated gastritis Traditional Chinese medicine Signalling pathway Eliminate pathogens Strengthen the body

Effects of sand burial on dune plants: a review

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Cold and Arid Regions 2014年第3期6卷 201-208页

作者： hao qu HaLin Zhao RuiLian Zhou Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences School of Life Science Ludong University

Burial of different growth stages of plants （e.g., adult plants, seedlings and seeds） is frequent in dune ecosystems. The soil micro-environment, which differs from surface conditions, influences the survival and growth of dune plants. To sum up knowledge about the survival mechanisms of plants under sand burial and to promote practical rehabilitation of dune vegetation, we reviewed relevant published literature and concluded that：（1） Focus in recent years has been on impacts of sand burial on seed germination and seedling emergence. Generally, shallow burial increased seed germination and seedling emergence, but deeper burial was negative. Buried at the same depth, large seeds showed higher germination and seedling emergence rates, attributed to larger energy reserves. （2） Survival, growth and reproduction rates of dune plants show plasticity in response to sand burial. Long-term deep burial is fatal because it creates a physical barrier which overcomes the vertical growth of plants, reduces photosynthetic leaf area, and limits oxygen availability to roots. Modest burial, on the other hand, is advantageous for growth and reproduction of many dune plants, due to protection from excessive temperature and drought. （3） There are few reports concerning effects of sand burial on plant physiology, but a limited number of studies indicate that partial burial increases water use efficiency, chlorophyll content, transpiration rate and net photosynthetic rates. The antioxidant protective enzyme system and osmolyte balance were reported to be involved in the mechanisms of dune plant resistance to burial.

关键词： sand burial dune plants survival growth and reproduction physiological response

Extraordinary tunable dynamic range of electrochemical aptasensor for accurate detection of ochratoxin A in food samples

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2017年第2期6卷 70-76页

作者： Lin Cheng hao qu Jun Teng Li Yao Feng Xue Wei Chen School of Food Science and Engineering Hefei University of TechnologyHefei230009China College of Veterinary Medicine Nanjing Agricultural UniversityNanjing210095China

We report the design of a sensitive,electrochemical aptasensor for detection of ochratoxin A(OTA)with an extraordinary tunable dynamic sensing *** electrochemical aptasensor is constructed based on the target induced aptamer-folding detection mechanism and the recognition between OTA and its aptamers results in the conformational change of the aptamer probe and thus signal changes for *** dynamic sensing range of the electrochemical aptasensor is successfully tuned by introduction of free assistant aptamer probes in the sensing *** electrochemical aptasensor shows an extraordinary dynamic sensing range of 11-order magnitude of OTA concentration from 10^−8 to 10^2 ng/*** great significance,the signal response in all OTA concentration ranges is at the same current scale,demonstrating that our sensing protocol in this research could be applied for accurate detections of OTA in a broad range without using any complicated treatment of signal ***,OTA spiked red wine and maize samples in different dynamic sensing ranges are determined with the electrochemical aptasensor under optimized sensing *** tuning strategy of dynamic sensing range may offer a promising platform for electrochemical aptasensor optimizations in practical applications.

关键词： Electrochemical aptasensor Tunable dynamic detection range OTA detection Extraordinary dynamic range