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Journal of Earth Science 2020年第2期31卷 223-236页

作者： Yang Huang hao deng State Key Laboratory of Geological Processes and Mineral Resources Center for Global TectonicsSchool of Earth SciencesChina University of GeosciencesWuhan 430074China

The chrome spinel(chromite)in mantle peridotites from ophiolites can shed light on the formation and evolution process of *** chromites were found in the Late Proterozoic Miaowan ophiolitic complex(MOC),Yangtze *** to the metamorphism and intense deformation,most chromite grains in the MOC peridotites show typical chemical zoning(core-rim texture).The values of major and trace elements largely vary from core to rim within chromite grains,indicating that the chromites have undergone strong alteration and element *** and trace elements in the core parts of chromites are used to infer the tectonic origins and evolution of mantle peridotites in the *** chromites from the MOC peridotites have higher Cr#values and lower Ni and Ga contents with respect to those from Phanero-zoic mantle peridotites,indicating a higher degree of ***-situ major and trace elements(e.g.,Ga)characteristics of podiform chromites in the MOC show that chromites from both harzburgites and dunites have strong subduction-related signatures,indicating that the MOC has formed in a supra-subduction setting which is consistent with the geological and geochemical data presented in previous studies.

关键词： podiform chromite Miaowan ophiolitic complex trace elements Precambrian Yangtze Craton

淫羊藿苷预处理增强人牙周膜干细胞对M1型巨噬细胞的影响

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中国组织工程研究 2025年第7期29卷 1328-1335页

作者：喻婷吕冬梅邓浩孙涛程钎西南医科大学口颌面修复重建和再生泸州市重点实验室四川省泸州市646000 西南医科大学口腔医学研究所四川省泸州市646000 西南医科大学附属口腔医院正畸科四川省泸州市646000 西南医科大学口腔医学院四川省泸州市646000

背景:人牙周膜干细胞对M1型巨噬细胞促炎功能有一定抑制作用,具有抗炎等药理活性的淫羊藿苷是否能增强人牙周膜干细胞对M1型巨噬细胞的抑制作用尚不明确。目的:探究淫羊藿苷预处理人牙周膜干细胞后对M1型巨噬细胞的影响。方法:分离培养... 详细信息

背景:人牙周膜干细胞对M1型巨噬细胞促炎功能有一定抑制作用,具有抗炎等药理活性的淫羊藿苷是否能增强人牙周膜干细胞对M1型巨噬细胞的抑制作用尚不明确。目的:探究淫羊藿苷预处理人牙周膜干细胞后对M1型巨噬细胞的影响。方法:分离培养原代人牙周膜干细胞,并进行鉴定。对THP-1细胞进行诱导,采用免疫荧光染色及PCR进行M1型巨噬细胞鉴定。用含浓度10^(-7),10^(-6),10^(-5),10^(-4)mol/L淫羊藿苷的α-MEM完全培养基培养人牙周膜干细胞1,3,5,7 d,采用CCK-8法筛选合适的淫羊藿苷浓度进行实验。将α-MEM完全培养基、未处理的人牙周膜干细胞α-MEM条件培养基及淫羊藿苷预处理24 h的人牙周膜干细胞α-MEM条件培养基与RPMI-1640完全培养基以1∶1的比例对M1型巨噬细胞进行条件培养,分别为对照组、未处理组及预处理组,24 h后RT-PCR法检测M1型巨噬细胞炎症因子的mRNA表达情况;ELISA法检测M1型巨噬细胞炎症因子的蛋白表达情况;Western blot检测M1/M2型巨噬细胞表面标记物及核转录因子κB通路相关蛋白的表达。结果与结论:(1)CCK-8检测结果显示,10^(-7),10^(-6),10^(-5),10^(-4)mol/L淫羊藿苷对人牙周膜干细胞均无细胞毒性,且从第5天起,各浓度都提高了细胞活力,促进细胞增殖,选择10^(-4)mol/L淫羊藿苷进行后续实验。(2)RT-PCR法及ELISA检测结果显示,与对照组相比,未处理组及预处理组均降低了M1型巨噬细胞白细胞介素1β、白细胞介素6及肿瘤坏死因子α的表达与分泌(P<0.05),且预处理组低于未处理组(P<0.05)。(3)Western blot检测结果显示,与未处理组相比,预处理组CD86的表达明显降低(P<0.05);与对照组相比,未处理组和预处理组M2型巨噬细胞表面标志物CD206的表达均升高(P<0.01),且预处理组明显高于未处理组(P<0.01);M1型巨噬细胞经24 h条件培养后,与对照组相比,核转录因子κB/P65的表达在未处理组和预处理组均有降低(P<0.01),p-IκBα的表达仅在预处理组降低(P<0.01);与未处理组相比,预处理组核转录因子κB/P65和p-IκBα的表达均显著降低(P<0.05),而IκBα在3组中的表达差异无显著性意义。(4)上述结果证实,淫羊藿苷增强了人牙周膜干细胞对M1型巨噬细胞的抑制作用,此作用可能与抑制了巨噬细胞的核转录因子κB信号通路相关。

关键词：人牙周膜干细胞淫羊藿苷巨噬细胞条件培养基共培养表面标志物炎症因子抗炎核转录因子κB信号通路

Human genetic basis of coronavirus disease 2019

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Signal Transduction and Targeted Therapy 2021年第10期6卷 2981-2994页

作者： hao deng Xue Yan Lamei Yuan Health Management Center the Third Xiangya HospitalCentral South UniversityChangshaChina Center for Experimental Medicine the Third Xiangya HospitalCentral South UniversityChangshaChina Disease Genome Research Center Central South UniversityChangshaChina Department of Neurology the Third Xiangya HospitalCentral South UniversityChangshaChina

Coronavirus disease 2019(COVID-19)caused by a novel coronavirus,severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has resulted in considerable morbidity and mortality ***-19 incidence,severity,and mortality rates differ greatly between populations,genders,ABO blood groups,human leukocyte antigen(HLA)genotypes,ethnic groups,and geographic *** highly heterogeneous SARS-CoV-2 infection is *** genetic factors such as variants in the angiotensin-converting enzyme gene(ACE),the angiotensin-converting enzyme 2 gene(ACE2),the transmembrane protease serine 2 gene(TMPRSS2),along with HLA genotype,and ABO blood group help to explain individual susceptibility,severity,and outcomes of *** review is focused on COVID-19 clinical and viral characteristics,pathogenesis,and genetic findings,with particular attention on genetic diversity and *** human genetic basis could provide scientific bases for disease prediction and targeted therapy to address the COVID-19 scourge.

关键词： mortality ABO acute

Preferential oxidation of CO in excess H_2 over CeO_2/CuO catalyst:Effect of calcination temperature

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Journal of Natural Gas Chemistry 2012年第5期21卷 513-518页

作者： Zhiming Gao Ming Zhou hao deng Yong Yue Key Laboratory of Cluster Science Ministry of Education of China School of Chemistry Beijing Institute of TechnologyBeijing 100081China Research Department of Environmental Technology CNPC Research Institute of Safety and Environmental TechnologyBeijing 100083China

Different from the classical configuration CuO/CeO2 catalyst,the inverse configuration CeO2 /CuO catalyst （atomic ratio of Ce/Cu=10/100） was prepared by impregnation *** calcination temperatures were selected to investigate the interaction between CeO2 and CuO *** is found that as calcination temperature increased from 500 to 900 C,sintering of CeO2 particles on the support occurred together with the diffusion of a portion of Ce 4＋ ions into CuO crystals,forming solid *** of interface complex Ce-O-Cu was suggested by TPR *** catalyst calcined at 700 C gives the highest activity for preferential oxidation of CO in excess H2 stream.

关键词： preferential oxidation carbon monoxide cerium oxide cupric oxide TPR

Numerical investigation of complex chemistry performing in Ptcatalyzed oxidative dehydrogenation of ethane fixed-bed reactors

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Chinese Journal of Chemical Engineering 2020年第3期28卷 793-807页

作者： Zhongfeng Geng hao deng Yonghui Li Minhua Zhang Key Laboratory for Green Chemical Technology of Ministry of Education.R&D Center for Petrochemical Technology Tianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072China

Ethylene is one of the most important basic chemicals in the modern chemical *** or catalytic cracking of hydrocarbons is the main industrial technologies nowadays,which suffer from equilibriumlimitation and rapid coke *** oxidative dehydrogenation of ethane(ODHE)is considered to be a promising alternative process since it overcomes equilibrium-limitations,avoids catalyst deactivation by coke formation,and decreases the number of side *** this study,particle-resolved 2 D CFD simulations of fixed-beds filled with eggshell catalysts coupled with micro-kinetics of Pt-catalyzed ODHE were performed to understand the effect of operation conditions and catalyst properties on ethylene *** catalyst bed was created by discrete element method(DEM)and the central longitudinal section of the reactor tube was defined as the 2 D simulation *** of the homogeneous and catalytic heterogeneous chemical reactions were described by detailed micro-kinetics within the particle-resolved CFD *** first,the established model of monolith reactors was verified by comparing the simulated results with experimental results reported in ***,the effects of operation conditions and catalyst concentration on the ethylene selectivity in randomly packed beds were *** specific variation of certain operation conditions including inlet flow rate,inlet temperature,pressure,inlet C2 H6/O2 ratio and N2 dilution ratio can effectively increase ethylene *** the reduction of ratio of catalytic active area to geometric area Fcat/georepresenting catalyst properties from 140 to 30 increases the selectivity from 42.2%to 59.3%.This research can provide reference for the industrialization of ODHE process in the future.

关键词： Ethane Ethylene Oxidative dehydrogenation Selectivity CFD Fixed-bed

Pure and stable white organic light-emitting device with an ultra-thin layer

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Chinese Science Bulletin 2006年第19期51卷 2301-2303页

作者： hao Jingang deng Zhenbo Key Laboratory of Luminescence and Optical Information Ministry ofEducation Institute of Optoelectronic Technology Beijing JiaotongUniversity Beijing 100044 China

An ultra-thin (3 nm) hole blocking layer, 2,9-dimethyl-4,7-diphenyl-1,10-phenanthroline (BCP) was inserted between the electron-transport layer of 8-hydroxyquinoline aluminum (Alq3) and 4-(dicyan- omethylene)-2-t-butyl-6(1,1,7,7-tetramethyljulolidyl-9- enyl)-4H-pyran (DCJTB) doped poly-vinylcarbazole (PVK) layer. The device structure was ITO/PVK: DCJTB(0.25 wt%)/BCP(3 nm)/Alq3(8 nm)/Al. Because the thickness of BCP was on the scale of Forster energy transfer critical radius, incomplete energy transfer would occur from PVK to Alq3 and then from Alq3 back to DCJTB through BCP layer. Furthermore, BCP can block a hole from migrating ahead, and thus confine excitons formed in the emission layer. The optimized device gives pure and voltage-independent emission. The CIE coordinate was kept at (0.32, 0.32), and the brightness reached 270 cd/m2 at 18 V with the efficiency of 0.166 cd/A.

关键词： OLED 白色发光二极管超薄层能量转变邻二氮杂菲

The morphological evolution of Chinese urban cemeteries from the perspective of fringe belt:A case study of Nanjing

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Frontiers of Architectural Research 2023年第6期12卷 1065-1079页

作者： hao deng Meichen Li School of Architecture Southeast UniversityNanjing 210096China

The urban cemetery is the material carrier of citizens’view of life and death,and it also evolves with time as a special part of the urban *** the reform of the housing system in the 1990s,China has entered a period of rapid urbanization,and the urban cemeteries has entered a cycle of shock and accelerated *** cemeteries originally located on the urban fringe were gradually surrounded by new built-up areas as the city sprawled,and then most of them inevitably migrated outward under the pressure of urban population explosion and land *** Nanjing as an example,this paper presents the morphological evolution of Nanjing’s urban cemetery since the early 20th century,discusses the relationship between the evolution of the cemetery and the urban fringe belt,and analyzes the reasons for its *** different types of morphological evolution of Nanjing cemetery are further summarized,revealing the general law and its Chinese *** article concludes with a discussion of the value and significance of morphological research on urban cemeteries in China.

关键词： Urban cemetery View of life and death Urban morphology Fringe belt Move Nanjing

A mathematical morphology-based multi-level filter of LiDAR data for generating DTMs

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Science China(Information Sciences) 2013年第10期56卷 144-157页

作者： CHEN Dong ZHANG LiQiang WANG Zhen deng hao State Key Laboratory of Remote Sensing Science Beijing Normal University

Light detecting and ranging(LiDAR)technology has become an efective way to generate highresolution digital terrain models(DTMs).To generate DTMs,point measurements from non-ground features,such as buildings,vegetation and vehicles,have to be identifed and removed while preserving the terrain *** paper proposes an efcient mathematical morphology-based multi-level flter to generate DTMs from airborne LiDAR *** non-ground points are frst identifed with the characteristics of the multiecho airborne LiDAR *** localized mathematical morphology opening operations are then immediately applied to the remaining *** gradually increasing the window size of the flter and using a dynamic critical gradient threshold,the non-ground points are removed,while the ground points are *** samples were chosen from eight sites provided with the ISPRS Commission III,Working Group 3,to evaluate the accuracy of our *** the qualitative and quantitative experiment analyses show that our morphologybased multi-level flter method achieves promising results,not only in flat urban areas but also in rural areas,especially in preserving complex terrain details,while non-ground spatial objects are removed.

关键词： LiDAR mathematical morphology multi-level flter DTMs

The likely counterpart to γ-ray excess from the northwest region of Arp 220

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Research in Astronomy and Astrophysics 2021年第7期21卷 171-176页

作者： Yun-Chuan Xiang Jun-hao deng Ze-Jun Jiang Department of Astronomy Yunnan Universityand Key Laboratory of Astroparticle Physics of Yunnan ProvinceKunming 650091China

The unknown γ-ray excess in the northwest region of Arp 220 was revisited by analyzing~11.8 years of the Fermi Large Area Telescope(Fermi-LAT) data in this *** found that its photon flux was approximately three times higher than that of the previous study in the 0.2-100 GeV band,and the corresponding significance level ~8.15σ was approximately four times higher than *** light curves of 15 and 45 time bins from the whole time all showed two active periods,and the variability of the second period was more significant than that of the first *** spectral indices from the two active periods were not statistically different and were close to the range of γ-ray flat-spectrum radio quasars observed by *** the position of CRATES J153246+234400 was consistent with the best-fit position of our analysis,we suggest that CRATES J153246+234400 is more likely a γ-ray counterpart for the variational *** Arp 220,there was no significant variability in the γ-ray emission.

关键词： flat spectrum radio quasar:individual(CRATES J153246+234400) quasars γ-ray emission

Improved analysis of the rare decay processes of Λ_(b)

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Communications in Theoretical Physics 2021年第10期73卷 114-124页

作者： Ren-hao deng Yong-lu Liu Ming-qiu Huang College of Art and Science National University of Defense TechnologyHunan 410073China

It is noted that in the new Particle Data Group(PDG) version the rare decays of the Λ_(b) baryon have been revised with more accuracy. The new results show that most of the existing theoretical results on the process Λ_(b)→Λ_(γ) Lgbare larger than those of experiments. With the improved higher-order light-cone distribution amplitudes of the Λ baryon, we reanalyze the process in the framework of light-cone quantum chromodynamics sum rules and the branching ratio is estimated to be Br (Λ_(b)→Λ_(γ))=(7.38-0.39+0.40)×10^(16), which is consistent with the new experimental result. Furthermore, another process Λ_(b)→Λl+l- is also analyzed in the same frame. The final branching ratio is calculated to be Br (Λ_(b)→Λl+l-)=1.20×10^(-6), which is in good accordance with the data from the PDG and other theoretical predictions.

关键词： light-cone distribution amplitude rare decay light-cone QCD sum rules