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Open Journal of Anesthesiology 2020年第1期10卷 1-12页

作者： Assem Adel Moharram hany hasan elsayed Faculty of Medicine Ain Shams University Cairo Egypt

Objective The benefits and risks of using double lumen tube (DLT) in open thoracotomy are not well studied and the relative contraindication for using it in cases of endobronchial tumours is not proven. In this study, we compared our experience with using DLT versus single lumen tube (SLT) for anesthesia in patients requiring an open thoracotomy for resection of endobronchial tumours. Methods A prospective observational study was performed in a single tertiary care university hospital in patients with endobronchial tumours anesthetized with single and double lumen tubes for open thoracotomy procedures over a period from 2010 till 2018. Results One hundred and six patients with endobronchial tumours were studied. There were 76 males. Median age was 32 years (14 - 62). In 96 cases, endobronchial pathology was a typical carcinoid. 58 patients were anesthetized using a DLT and 48 using a SLT. Four cases of near miss from potentially fatal intraoperative tumour migration occurred in the SLT group (p = 0.025). There was only one case of mild tumour bleeding from the DLT group and time of insertion was longer (16.2 vs. 4.5 min p Conclusions We conclude that it is safe to place a double lumen endo tracheal tube for patients with endobronchial tumours requiring open lobectomies or bronchoplastic procedures. An additional benefit of DLT use is increasing surgical satisfaction by reducing spillage and tidal volume loss during surgical anastomosis of the open airway.

关键词： Double Lumen Tube Endobronchial Tumor Thoracotomy

DNA damage in hemocytes of Schistocerca gregaria (Orthoptera: Acrididae) exposed to contaminated food with cadmium and lead

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Natural Science 2010年第4期2卷 292-297页

作者： Hesham A. Yousef Amira Afify hany M. hasan Afaf Abdel Meguid 不详

We measured in a comet assay the damage of DNA in the hemocytes of various stages of the grasshopper Schistocerca gregaria after ex-posing them to various doses of Cd and Pb in the food. The mechanisms of Cd and Pb toxicity for grasshopper are discussed. The accumula-tion of heavy metals and stage of the insect may play important roles in causing the DNA damage. S. gregaria may be considered a valuable bio-indicator for evaluation the genotoxicity of en-vironmental pollutants.

关键词： Comet Assay Heavy Metals (Cd Pb) DNA Damage Schistocerca gregaria

Biliary complications in recipients of living donor liver transplantation:A single-centre study

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World Journal of Hepatology 2021年第12期13卷 2081-2103页

作者： Reginia Nabil Guirguis Ehab hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh Mohamed Bahaa Mahmoud El-Meteini Mohamed Fathy hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman Mohamed Gastroenterology and Hepatology Unit Department of Internal MedicineFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of General Surgery Faculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Tropical Medicine Faculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Biliary complications(BCs)after liver transplantation(LT)remain a considerable cause of morbidity,mortality,increased cost,and graft *** To investigate the impact of BCs on chronic graft rejection,graft failure and *** From 2011 to 2016,215 adult recipients underwent right-lobe living-donor liver transplantation(RT-LDLT)at our *** excluded 46 recipients who met the exclusion criteria,and 169 recipients were included in the final ***’and recipients’demographic data,clinical data,operative details and postoperative course information were *** also reviewed the management and outcomes of *** were followed for at least 12 mo post-LT until December 2017 or graft or patient *** The overall incidence rate of BCs including biliary leakage,biliary infection and biliary stricture was 57.4%.Twenty-seven(16%)patients experienced chronic graft *** failure developed in 20(11.8%)patients.A total of 28(16.6%)deaths occurred during *** were a risk factor for the occurrence of chronic graft rejection and failure;however,mortality was determined by recurrent hepatitis C virus *** Biliary complications after RT-LDLT represent an independent risk factor for chronic graft rejection and graft failure;nonetheless,effective management of these complications can improve patient and graft survival.

关键词： Biliary complications Living donor liver transplantation Retrospective analysis Bile leak Biliary stricture Risk factors Mortality Graft rejection

Outcomes of complete surgical repair versus palliative intervention in neonates with Tetralogy of Fallot

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Pediatric Investigation 2022年第4期6卷 260-263页

作者： Mohammed Hamzah hasan FOthman Krystel Chedid Mohammed Alsabri Ibrahim Qattea hany Aly Department of Pediatric Critical Care Cleveland Clinic Children’sClevelandOhioUSA Department of Pediatrics Michigan State University/Sparrow Health SystemLansingMichiganUSA Department of Pediatrics Cleveland Clinic Children’sClevelandOhioUSA Department of Pediatrics Brookdale HospitalNew York CityNew YorkUSA Department of Neonatology Cleveland Clinic Children’sClevelandOhioUSA

The ideal surgical approach when managing neonates with Tetralogy of Fallot(TOF)is still controversial.1 In 1945,subclavian artery to pulmonary artery anastomosis was created as palliation for patients with TOF.2 A decade later,Lillehei et al.3 performed the first intracardiac repair for TOF with ventricular septal defect closure and right ventricular outflow obstruction *** surgical and perfusion techniques,as well as the postoperative care,have advanced and evolved since that *** that evolution,the two concepts of surgical interventions had remained the *** is still much debate on what is the ideal surgical approach to infants with TOF,an early primary surgical repair(EPSR)versus a two-staged surgical approach with either an initial temporary shunt for pulmonary blood flow or transcatheter cardiac *** aim of this study was to determine if one strategy had lower mortality than the other and to assess the hospital length of stay and cost of charge in the study groups.

关键词： surgical nates repair

Impact of biliary complications on quality of life in live-donor liver transplant recipients

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World Journal of Hepatology 2021年第10期13卷 1405-1416页

作者： Reginia Nabil Guirguis Ehab hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh Mohamed Bahaa Mahmoud El-Meteini Mohamed Fathy hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman Mohamed Department of Internal Medicine Gastroenterology and Hepatology UnitFaculty of MedicineAin Shams UniversityCairo 11591Egypt Department of General Surgery Faculty of MedicineAin Shams UniversityCairo 11591Egypt Department of Tropical Medicine Faculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft *** addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT ***,the success of LT should be considered in terms of both the survival and recovery of *** To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our *** Short Form 12 version 2(SF 12v2)health survey was used to assess their *** also included 25 LDLT-Rs without any post-LT complications as a control *** The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary *** The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL.

关键词： Live-donor liver transplantation Quality of life The Short Form 12 version 2 Cirrhosis Biliary complications Mental health

Development of Primary Percutaneous Coronary Intervention as a National Reperfusion Strategy for Patients with ST-Elevation Myocardial Infarction and Assessment of Its Use in Egypt

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Cardiovascular Innovations and Applications 2020年第2期4卷 269-278页

作者： Mohamed Sobhy Ahmed Elshal Noha Ghanem Hosam hasan-Ali Nabil Farag Nireen Okasha El Sayed Farag Mohamed Sadaka Hisham Abo El Enein Sameh Salama Hazem Khamis Khaled Shokry hany Ragy Amany Elshorbagy Radwa Mehanna Cardiology Department Faculty of MedicineAlexandria University HospitalAlexandriaEgypt International Center for Organization and Marketing AlexandriaEgypt Cardiology Department Faculty of Medicine Assiut University HospitalAssiut GovernorateEgypt Cardiology Department Faculty of Medicine Ain Shams University HospitalHeliopolisEgypt Cardiology Department Nasser InstituteCairoEgypt Cardiology Department Faculty of MedicineZagazig University HospitalZagazigEgypt Cardiology Department Faculty of MedicineBanha University HospitalBanhaEgypt Cardiology Department Faculty of MedicineKasr El Ainy HospitalKasr Al AinyEgypt Cardiology Department Wady El Nile HospitalZeitounEgypt Cardiology Department Military HospitalHeliopolisCairoEgypt Cardiology Department National Heart InstituteHeliopolisCairoEgypt Physiology Department Faculty of MedicineAlexandria UniversityAlexandriaEgypt

Objective:Early treatment of acute ischemia of the heart by performing immediate percutaneous coronary intervention(PCI)to restore blood fl ow in patients with the clinical presentation of an acute coronary syndrome and more specifi cally with ST-elevation myocardial infarction(STEMI)can save *** study aims to identify the mean time(door to balloon time and fi rst contact to balloon time)to primary PCI for STEMI patients and to assess the percentage of primary PCI and its success rate in ***:A registry study of patients presenting to cardiac centers in Egypt was designed,where patients’basic characteristics,the treatment strategy,and the door to balloon time and the fi rst contact to balloon time were ***:One thousand six hundred fi fty STEMI patients with a mean age of 57 years were included in the *** transfer for primary PCI was the most used treatment strategy,representing 74.6%of all treatment strategies *** door to balloon time and the fi rst contact to balloon time were 50 and 60 minutes,respectively,with a primary PCI success rate of 65.1%.Conclusion:The registry study results showed a marked improvement by implementation of the best treatment strategy with respect to the time factor to achieve a better outcome for STEMI patients in Egypt.

关键词： ST-elevation myocardial infarction primary percutaneous coronary intervention door to balloon time fi rst medical contact to balloon time