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肠易激综合征和胶原性结肠炎患者粪便中炎性标志物的检测

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世界核心医学期刊文摘（胃肠病学分册） 2006年第6期2卷 55-56页

作者： LettesjH. hansson T. Peterson c. M. Simrén 徐瑞 Sec.ion of Gastroenterology and Hepatology Department of Internal Medicine Sahlgrenska University Hospital SE-413 45 Gteborg Sweden Dr.

Objec.ive. Irritable bowel syndrome (IBS) and c.llagenous c.litis (c.) share c.ronic.lly rec.rring symptoms of altered bowel habits assoc.ated with abdominal pain or disc.mfort. The aims of the present study were to investigate whether inflammatory markers c.uld be detec.ed in faec.s from patients with IBS and c., and to eluc.date whether suc. analyses c.uld be used as non-invasive tools to distinguish between these disorders. Material and methods. Stool samples were obtained from 18 patients with c., 46 patients with IBS and 20 healthy c.ntrols (Hc.. Eosinophil protein X (EPX), myeloperoxidase (MPO), tryptase, interleukin-1 beta (IL-1β) and tumour nec.osis fac.or alpha (TNFα) were measured in supernatants from proc.ssed faec.s using immunoassays. Results. EPX levels were enhanc.d in faec.s from c. patients (median 3.8 μg/g (0.47-16.2)) c.mpared to patients with IBS (0.44 μg/g (0.25-1.8)), p c.(0.46 μg/g (0.21-1.3)), p c.eased in c. patients (11.7 μg/g (2.0-124)) c.mpared to IBS patients (1.7 μg/g (0.81-5.2)), p c.(2.5 μg/g (1.1-6.3)), p c., 6/46 with IBS and 1/19 Hc. IL-1βwas only enhanc.d in 2/11 c. patients and TNFαwas not detec.ed in any sample. c.nc.usions. Inc.eased levels of EPX, MPO and tryptase were observed in stools from c.llagenous c.litis patients, whereas the levels in IBS patients did not differ from healthy c.ntrols. Our data suggest that faec.l markers c.uld be used as part of the c.inic.l work-up to determine whic. patients should be biopsied and evaluated for c.llagenous c.litis.

关键词：肠易激综合征(IBS) 胶原性结肠炎炎性标志物患者粪便肿瘤坏死因子-α(TNF-α) 检测素-1β(IL-1β) 功能紊乱性疾病 IBS患者髓过氧化物酶

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心房颤动——当今面临的挑战

中华心律失常学杂志 1997年第1期1卷 58-62页

作者： Olsson SB hansson A Hedin E Holm M Ingemansson M Johansson R Meurling c.Pehrson S Roijer A Yuan S 方丕华瑞典Lund大学医院心内科

在过去数年里，临床和科撞方面对心房颤动(房颤)的关注明显增加，有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常，包括其不良后果和症状，房颤... 详细信息

在过去数年里，临床和科撞方面对心房颤动(房颤)的关注明显增加，有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常，包括其不良后果和症状，房颤无疑是虽迫切需要有更好治疗方法的一种心律失常。为了达到这一目的，就需要更深刻地认识房颤的机制．以便开发直接影响这一基础病理生理机制的治疗措施。

关键词：心房颤动心律失常治疗措施病理生理机制基础病不良后果患者临床治疗方法挑战

Antibodies to hepatitis c.virus and hepatitis c.virus RNA in c.inese blood donors determined by ELISA, rec.mbinant immunoblot assay and polymerase c.ain reac.ion

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中华医学杂志(英文版) 1993年第3期106卷 174-174页

作者： Y Y Zhang L S Guo L J Hao B G hansson A Widell E Nordenfelt c.inic.l Immunology Researc. Unit Tongji Hospital Tongji Medical University Wuhan.

Antibodies to hepatitis c.virus (anti-Hc.) were determined in c.inese blood donors from the c.ty of Wuhan by ELISA sc.eening tests and c.nfirmatory rec.mbinant immunoblot assay (RIBA). 281 and 222 sera were sampled under similar c.nditions in 1989 and 1990, respec.ively. The first c.llec.ion of sera was sent to Sweden in lyophilized form, the sec.nd direc.ly as fresh, unfrozen sera. A high proportion (22%) of the lyophilized sera were positive in the sc.eening assay but only 6 (2.10%) were positive by RIBA with antibodies against both the c.00-3 and 5-1-1 peptides. Hc. RNA c.uld be detec.ed by polymerase c.ain reac.ion (Pc.) analysis in 3 of the 6 sera and in one reac.ing with c.00-3 only. In the sec.nd material of fresh sera only 3 were positive in the sc.eening anti-Hc. ELISA, but none was RIBA or Pc. positive. Thus, the overall prevalenc. of anti-Hc. among the 503 c.inese blood donors as identified by RIBA was 1.2%, and that of Hc. RNA by Pc. was 0.8%. The c.nfirmed antibody prevalenc. is higher than that reported in the western literature.

关键词： NON-B-HEPATITIS NON-A VIRAL SEQUENc.S INFEc.IVITY EXPERIENc.

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一般男性人群脑卒中的决定因素:1913年出生男性的48年随访研究

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中华高血压杂志 2019年第1期27卷 24-24页

作者：刘青叶鹏 Persson c. Sv?rdsudd K Rusek L Blomstrand c.Blomstrand A Welin L Wilhelmsen L hansson PO

为了进一步完善预防脑卒中的策略,有必要进行流行病学的长期研究。该研究旨在对普通男性人群中脑卒中的决定因素进行前瞻性研究。方法:在年龄50~98岁的48年期间,通过反复体检,生活方式问卷调查,医院记录数据和全国死因登记等数据,对854... 详细信息

为了进一步完善预防脑卒中的策略,有必要进行流行病学的长期研究。该研究旨在对普通男性人群中脑卒中的决定因素进行前瞻性研究。方法:在年龄50~98岁的48年期间,通过反复体检,生活方式问卷调查,医院记录数据和全国死因登记等数据,对854名男性进行了人口抽样调查。

关键词：脑卒中心房颤动 HR 男性人群决定因素

治疗PauwelsⅡ型股骨颈骨折,股骨颈系统(FNS)比hansson钉稳定性更好、固定更可靠

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临床骨科杂志 2021年第5期24卷 634-634页

作者： Sc.OPPER c.ZDERIc.I MENZE J 胡孔足(摘译) 不详

股骨颈系统(FNS)是近年来开发的新型固定系统,作者为了研究其生物力学特性,制作了PauwelsⅡ型股骨颈骨折模型,分别使用FNS和hansson钉固定,比较两组生物力学特性。采用14组新鲜冰冻股骨,制作40°PauwelsⅡ型股骨颈骨折以及后方15°楔形... 详细信息

股骨颈系统(FNS)是近年来开发的新型固定系统,作者为了研究其生物力学特性,制作了PauwelsⅡ型股骨颈骨折模型,分别使用FNS和hansson钉固定,比较两组生物力学特性。采用14组新鲜冰冻股骨,制作40°PauwelsⅡ型股骨颈骨折以及后方15°楔形骨折块模型,以两种方法固定后施加循环加载,直至结构失效。结果发现,加载至10°内翻次数FNS组为(23007±5496)次,显著高于hansson钉组的(17289±4686)次;加载至10°股骨头背侧倾斜以及10°旋转次数两组无显著性差异。

关键词：股骨颈骨折生物力学特性内翻骨折,股骨颈背侧 Ⅱ型循环加载结构失效