整形外科支架中烷基硫脲的HPLC分析及纯已基丁基硫脲斑贴试验
HPLC analysis of alkyl thioureas in an orthopaedic brace and patch testing with pure ethylbutylthiourea作者机构:Department of Dermat ology University Hospital SE-221 85 Lund Sweden
出 版 物:《世界核心医学期刊文摘(皮肤病学分册)》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期:2005年第1卷第5期
页 面:24-24页
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题:整形外科 HPLC分析 斑贴试验 氯丁二烯橡胶 二硫代氨基甲酸 二丁基
摘 要:Ethylbutylthiourea (EBTU) is an accelerator used in the production of chloropr ene (neoprene) rubber. EBTU occurs in a mixture with diethylthiourea (DETU) and dibutylthiourea (DBTU) in the accelerator. An analytical method originally devel oped for analysis of zinc dithiocarbamates in rubber has been used to analyse EB TU, DETU and DBTU in a knee brace responsible for an allergic contact dermatitis in a gardener suffering from arthrosis. EBTU was isolated and gave positive rea ctions when tested as a pure compound. The test reaction was accompanied by posi tive reactions to DETU and DBTU.