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Research on sensorless control system of permanent magnet synchronous motor for CNC machine tool

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Research on sensorless control system of permanent magnet sy...

肺非终末呼吸单元型腺癌中PD-L1表达和CD8^(+)TILs的临床意义

第40届中国控制会议

作者： jiaxin Huo hanjie ji Peihao Yang College of Chemical Engineering Harbin Institute of Petroleum College of information science and engineering Ocean University of China Xi'an Thermal Power Research Institute Co. Ltd.

CNC machine tool is the foundation of modern machinery industry,and plays an important role in the development of national economy and the promotion of national comprehensive national *** development of servo drive control technology of CNC machine tool is the key to improve and improve the performance of machine tool in all *** magnet synchronous motor（PMSM） has become the mainstream of modern machine tool AC servo drive control system because of its simple structure,small size,light weight,high efficiency,high power factor,low moment of *** torque control（DTC） is a new high-performance variable frequency speed regulation technology after vector *** PMSM DTC system,the rotor position information is usually needed to realize the commutation operation of the motor,which is difficult to be used in some specific PMSM sensorless *** this paper,a sensorless direct torque control method for permanent magnet synchronous motor based on low speed pulse high frequency stator flux injection is proposed,and the stator flux estimator is improved to improve the accuracy of traditional stator flux estimator based on current *** are carried out to verify the effectiveness and feasibility of the proposed strategy.

关键词： CNC machine tool permanent magnet synchronous motor direct torque control sensorless stator flux

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现代肿瘤医学 2024年第7期32卷 1272-1277页

作者：季月霞杨阳张晗婕陶静霞郭天威刘倩刘标南京中医药大学常熟附属医院病理科江苏常熟215516 南京医科大学附属苏州医院病理科江苏苏州215006

目的:探讨肺非终末呼吸单元型(non-TRU)腺癌中PD-L1表达和CD8^(+)肿瘤浸润淋巴细胞(CD8^(+)TILs)的临床意义。方法:回顾性研究85例手术切除的临床分期为I-IV期的肺non-TRU型腺癌患者的临床病理资料,应用免疫组化方法检测PD-L1、p53和4... 详细信息

目的:探讨肺非终末呼吸单元型(non-TRU)腺癌中PD-L1表达和CD8^(+)肿瘤浸润淋巴细胞(CD8^(+)TILs)的临床意义。方法:回顾性研究85例手术切除的临床分期为I-IV期的肺non-TRU型腺癌患者的临床病理资料,应用免疫组化方法检测PD-L1、p53和4项错配修复蛋白(MLH1、MSH2、MSH6和PMS2)的表达以及CD8^(+)TILs,应用扩增阻滞突变系统(ARMS)和荧光原位杂交技术(FISH)检测EGFR、KRAS突变和ALK融合基因,并结合随访资料进行生存分析。结果:85例non-TRU腺癌中PD-L1阴性34例(40.0%)、低表达36例(42.4%)、高表达15例(17.6%),PD-L1表达更常见于有吸烟史(P0.05)。高密度CD8^(+)TILs患者的OS显著高于低-中密度患者(P0.05)。结论:肺non-TRU型腺癌常表达PD-L1并具有较高密度的CD8^(+)TILs,提示患者可能从ICIs治疗中获益,高密度CD8^(+)TILs可以作为一项辅助判断肺non-TRU型腺癌预后的指标。

关键词：肺腺癌非终末呼吸单元 PD-L1 CD8 TILs

Evidence for charge and spin density waves in single crystals of La_(3)Ni_(2)O_(7) and La_(3)Ni_(2)O_(6)

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Science China(Physics,Mechanics & Astronomy) 2023年第1期66卷 164-170页

作者： Zengjia Liu Hualei Sun Mengwu Huo Xiaoyan Ma Yi ji Enkui Yi Lisi Li Hui Liu jia Yu Ziyou Zhang Zhiqiang Chen Feixiang Liang Hongliang Dong hanjie Guo Dingyong Zhong Bing Shen Shiliang Li Meng Wang Center for Neutron Science and Technology Guangdong Provincial Key Laboratory of Magnetoelectric Physics and DevicesSchool of PhysicsSun Yat-sen UniversityGuangzhou 510275China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Center for High Pressure Science and Technology Advanced Research Shanghai 201203China Songshan Lake Materials Laboratory Dongguan 523808China

Charge and spin orders are intimately related to superconductivity in copper oxide *** of the competing orders in various nickel oxide compounds is crucial,given the fact that superconductivity has been discovered in Nd_(0.8)Sr_(0.2)NiO_(2)***,we report structural,electronic transport,magnetic,and thermodynamic characterizations of single crystals of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6).La_(3)Ni_(2)O_(7)is metallic with mixed Ni^(2+)and Ni^(3+)valent *** measurements yield two transition-like kinks at~110 and 153 *** kink at 153 K is further revealed from magnetization and specific heat measurements,indicative of the formation of charge and spin density ***_(3)Ni_(2)O_(6)single crystals obtained from the topochemical reduction of La_(3)Ni_(2)O_(7)are insulating and show an anomaly at~176 K on magnetic *** transition-like behaviors of La_(3)Ni_(2)O_(7)and La_(3)Ni_(2)O_(6)are analogous to those observed in La_(4)Ni_(3)O_(10) and La_(4)Ni_(3)O_(8),suggesting that charge and spin density waves are a common feature in the ternary La-Ni-O system with mixed-valent states of nickel.

关键词： charge-density-wave systems spin-density waves mixed-valence solids superlattices crystal growth

The marriage of Xenes and hydrogels:Fundamentals,applications,and outlook

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The Innovation 2022年第6期3卷 52-66页

作者： Yong Kang hanjie Zhang Liqun Chen jinrui Dong Bin Yao Xue Yuan Duotian Qin Alexey VYaremenko Chuang Liu Chan Feng Xiaoyuan ji Wei Tao Academy of Medical Engineering and Translational Medicine Medical CollegeTianjin UniversityTianjin 300072China Center for Nanomedicine and Department of Anesthesiology Brigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA Department of Respiratory Medicine Sir Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiang 310016China Tianjin Key Laboratory of Biomedical Materials Key Laboratory of Biomaterials and Nanotechnology for Cancer ImmunotherapyInstitute of Biomedical EngineeringChinese Academy of Medical Sciences and Peking Union Medical College Tianjin 300192China

Hydrogels have blossomed as superstars in various fields,owing to their prospective applications in tissue engineering,soft electronics and sensors,flexible energy storage,and ***-dimensional(2D)nanomaterials,especially 2D mono-elemental nanosheets(Xenes)exhibit high aspect ratio morphology,good biocompatibility,metallic conductivity,and tunable electrochemical *** fascinating characteristics endow numerous tunable application-specific properties for the construction of Xene-based *** multifunctional hydrogels can be prepared according to the application requirements and can be effectively tuned by different stimulation to complete specific tasks in a spatiotemporal *** this review,the synthesis mechanism,properties,and emerging applications of Xene hydrogels are summarized,followed by a discussion on expanding the performance and application range of both hydrogels and Xenes.

关键词： properties hydrogel summarized

Gold nanorods-mediated efficient synergistic immunotherapy for detection and inhibition of postoperative tumor recurrence

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Acta Pharmaceutica Sinica B 2021年第7期11卷 1978-1992页

作者： Yingying Zhang Tiange Wang Yu Tian Chaonan Zhang Kun Ge jinchao Zhang jin Chang hanjie Wang School of Life Sciences Tianjin UniversityTianjin 300072China Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology Tianjin Key Laboratory of Function and Application of Biological Macromolecular StructuresTianjin 300072China College of Chemistry&Environmental Science Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of EducationChemical Biology Key Laboratory of Hebei ProvinceHebei UniversityBaoding 071002China

Tumor recurrence after surgery is the main cause of treatment ***,the initial stage of recurrence is not easy to detect,and it is difficult to cure in the late *** order to improve the life quality of postoperative patients,an efficient synergistic immunotherapy was developed to achieve early diagnosis and treatment of post-surgical tumor recurrence,*** this paper,two kinds of theranostic agents based on gold nanorods(AuNRs)platform were *** and quantum dots(QDs)in one agent was used for the detection of carcinoembryonic antigen(CEA),using fluorescence resonance energy transfer(FRET)technology to indicate the occurrence of in situ recurrence,while AuNRs in the other agent was used for photothermal therapy(PTT),together with antiPDL1 mediated immunotherapy to alleviate the process of tumor metastasis.A series of assays indicated that this synergistic immunotherapy could induce tumor cell death and the increased generation of CD3;/CD4;T-lymphocytes and CD3+;CD8;***,more immune factors(IL-2,IL-6,and IFN-γ)produced by synergistic immunotherapy were secreted than *** cooperative immunotherapy strategy could be utilized for diagnosis and treatment of postoperative tumor recurrence at the same time,providing a new perspective for basic and clinical research.

关键词： Synergistic immunotherapy Post-surgical tumor recurrence Theranostics Gold nanorods Phototherapy Lung metastasis Fluorescence resonance energy transfer Carcinoembryonic antigen

Wafer-Scale Synthesis of WS_(2)Films with In Situ Controllable p-Type Doping by Atomic Layer Deposition

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Research 2021年第1期2021卷 1424-1432页

作者： hanjie Yang Yang Wang Xingli Zou Rongxu Bai Zecheng Wu Sheng Han Tao Chen Shen Hu Hao Zhu Lin Chen David W.Zhang Jack C.Lee Xionggang Lu Peng Zhou Qingqing Sun Edward T.Yu Deji Akinwande Li ji State Key Laboratory of ASIC and System School of MicroelectronicsFudan UniversityShanghai 200433China State Key Laboratory of Advanced Special Steel School of Materials Science and EngineeringShanghai UniversityShanghai 200444China Microelectronics Research Center Department of Electrical and Computer EngineeringThe University of Texas at AustinAustin78758 TexasUSA

Wafer-scale synthesis of p-type TMD films is critical for its commercialization in next-generation electro/*** this work,wafer-scale intrinsic n-type WS_(2)films and in situ Nb-doped p-type WS_(2)films were synthesized through atomic layer deposition(ALD)on 8-inchα-Al_(2)O_(3)/Si wafers,2-inch sapphire,and 1 cm^(2)GaN substrate *** Nb doping concentration was precisely controlled by altering cycle number of Nb precursor and activated by ***_(2)n-FETs and Nb-doped p-FETs with different Nb concentrations have been fabricated using CMOS-compatible processes.X-ray photoelectron spectroscopy,Raman spectroscopy,and Hall measurements confirmed the effective substitutional doping with *** on/off ratio and electron mobility of WS_(2)n-FET are as high as 105 and 6.85 cm^(2)V^(-1)s^(-1),*** WS_(2)p-FET with 15-cycle Nb doping,the on/off ratio and hole mobility are 10 and 0.016 cm^(2)V^(-1)s^(-1),*** p-n structure based on n-and p-type WS_(2)films was proved with a 10^(4)rectifying *** realization of controllable in situ Nb-doped WS_(2)films paved a way for fabricating wafer-scale complementary WS_(2)FETs.

关键词： sapphire doping realization

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斐济金棕叶斑病菌鉴定及生物学特性

植物保护 2009年第2期35卷 67-71页

作者：谢昌平谭翰杰张能纪烨斌海南大学环境与植物保护学院儋州571737

斐济金棕（Pritchardia pacifica Seem．＆***．）叶斑病主要发生在叶片。初期症状为病斑呈水溃状褪绿，后期病斑中央灰白色，病斑边缘有黄色晕圈。对斐济金棕叶斑病病菌进行形态学观察和生物学特性的测定结果表明：斐济金棕叶斑病菌鉴... 详细信息

斐济金棕（Pritchardia pacifica Seem．＆***．）叶斑病主要发生在叶片。初期症状为病斑呈水溃状褪绿，后期病斑中央灰白色，病斑边缘有黄色晕圈。对斐济金棕叶斑病病菌进行形态学观察和生物学特性的测定结果表明：斐济金棕叶斑病菌鉴定为卵形弯孢[Curwularia ovoidea（Hiroe＆Watan．）Muntanola]，菌丝生长适宜温度20~35℃，适宜pH5-6；分生孢子萌发的适宜温度为25~40℃；最适碳源为麦芽糖；最适氮源为硝酸钠；分生孢子的致死温度为55℃。

关键词：斐济金棕叶斑病卵形弯孢病原鉴定生物学特性

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基于社会依赖演化网的协同过程调控框架

南京理工大学学报 2018年第3期42卷 335-344页

作者：徐萍高济张登辉吕何新金智勇顾汉杰浙江树人大学信息科技学院浙江大学计算机科学与技术学院

针对跨管理域服务协同过程所面临的不可控制障碍,该文革新社会依赖表示理论以支持协同状态的变迁和过程演化。提出开发基于社会依赖演化网(SDEN)的协同过程调控框架,由社会依赖规范构成的SDEN、协同过程自管理机制驱动的执行规范的理性A... 详细信息

针对跨管理域服务协同过程所面临的不可控制障碍,该文革新社会依赖表示理论以支持协同状态的变迁和过程演化。提出开发基于社会依赖演化网(SDEN)的协同过程调控框架,由社会依赖规范构成的SDEN、协同过程自管理机制驱动的执行规范的理性Agents和社会承诺、承诺监管、信誉管理机制构成的社区协同监管体系3项技术组成。实验结果证明,该框架技术和方法可以主动检测并应对协同执行过程中出现的节点失效、服务超时、服务中断、支付违约等服务异常情况,使跨管理域协同过程变得可预测、可控和可信。

关键词：社会依赖演化网协同过程调控框架

香兰素在大孔吸附树脂上的吸附平衡、动力学及动态吸附过程

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生物加工过程 2018年第4期16卷 16-22页

作者：季迎春吴菁岚周精卫庄伟应汉杰南京工业大学生物与制药工程学院江苏先进生物与化学制造协同创新中心江苏南京211800

研究香兰素在大孔吸附树脂LX-02上的吸附平衡、动力学以及动态吸附和解吸过程。考察p H对香兰素吸附的影响,并测定不同温度条件下香兰素的吸附等温线。结果表明:树脂LX-02吸附香兰素的最适p H为4.5;Freundlich模型可以更好地拟合香兰素... 详细信息

研究香兰素在大孔吸附树脂LX-02上的吸附平衡、动力学以及动态吸附和解吸过程。考察p H对香兰素吸附的影响,并测定不同温度条件下香兰素的吸附等温线。结果表明:树脂LX-02吸附香兰素的最适p H为4.5;Freundlich模型可以更好地拟合香兰素吸附等温线(R2=1),香兰素在LX-02树脂上的吸附为放热过程,最大吸附量为162.96 mg/g。吸附动力学结果表明,香兰素吸附动力学符合准二阶动力学模型。香兰素在树脂上的传质速率随着温度和浓度的增加而增加,且20 min内即可达到吸附平衡。动态吸附和解吸实验发现,温度升高会导致香兰素在树脂上的吸附量降低,而流量对树脂吸附香兰素的影响可忽略不计,因此,最佳上柱条件为温度298.15 K、流量2 m L/min,最适解吸剂为0.05 mol/L Na OH。

关键词：香兰素大孔吸附树脂LX-02 吸附等温线动力学动态吸附和解吸