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Health 2022年第8期14卷 910-920页

作者： haiyan lin Chenyun Xu The Fourth People’s Hospital of Haikou Haikou China Hainan General Hospital Haikou China

Objective: To investigate the correlation between recurrent spontaneous abortion patients and brain derived neurotrophic factor BDNF gene polymorphism and the mechanism of BDNF and recurrent spontaneous abortion under stress state in order to provide theoretical basis for nursing psychological intervention of patients with recurrent abortion. Methods: Medical coping Questionnaire (MCMO) and post-traumatic stress Diagnostic Scale (POST-traumatic stress Scale) were adopted Dissorder (PTSD) (PCL-c) scale was used to diagnose the psychological stress of recurrent spontaneous abortion in our hospital, and the BDNF gene polymorphism and the correlation factors of METHYLation in BDNF promoter region were studied in 30 cases (control group) and normal control group. Results: The MCMQ score of the case group and the control group was significantly lower than that of the conventional group (P Conclusion: There are significant differences in PTSD between the case group and the control group, which are related to methylation in the PROMOTER region of BDNF and SNP g-712A of BDNF gene. AG patients in the case group are more susceptible to anxiety and depression, and GG PTSD is more severe in the case group. BDNF promoter methylation and G-712A were independent risk factors for PTSD in the case group.

关键词： Recurrent Spontaneous Abortion BDNF Psychological Care to Do

Review: Psychological Problems of Pregnant Women and Progress of Psychological Guidance in Recurrent Miscarriage

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Health 2021年第7期13卷 729-735页

作者： haiyan lin Chenyun Xu The Fourth People’s Hospital of Haikou Haikou China Hainan General Hospital Haikou China

In order to understand the psychological problems of pregnant women, this article explores the psychological problems and the sources of psychological stress of pregnant women who have a history of recurrent miscarriage after pregnancy. The analysis shows that the psychological stress of pregnant women may be one of the reasons for recurrent miscarriage. Strengthening mental health education during pregnancy can avoid the stimulation of bad emotions and environment, prevent the spontaneous abortion caused by psychological reasons, and improve the quality of pregnancy. It is particularly important to grasp the mental state of pregnant women with recurrent abortion timely and carry out corresponding psychological counseling and psychological nursing.

关键词： Pregnant Women Recurrent Abortion Psychological Factors Psychological Guidance

基于GA优化卷积神经网络的含分布式光伏低压台区电能质量扰动特征识别研究

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电子设计工程 2024年第3期32卷 120-124页

作者：张智轶段文方韦家义赵彬林海燕中冶建工集团有限公司重庆400084

针对扰动特征识别效果较差的问题,采用基于GA优化卷积神经网络的含分布式光伏低压台区电能质量扰动特征识别方法。获取各尺度扰动信号的分解系数,求解电扰动信号各尺度的能量值与能量熵,将能量值与能量熵当成扰动特征提取的依据,完成扰... 详细信息

针对扰动特征识别效果较差的问题,采用基于GA优化卷积神经网络的含分布式光伏低压台区电能质量扰动特征识别方法。获取各尺度扰动信号的分解系数,求解电扰动信号各尺度的能量值与能量熵,将能量值与能量熵当成扰动特征提取的依据,完成扰动特征提取;利用GA算法优化卷积神经网络结构参数,在优化后的卷积神经网络内输入提取的扰动特征,输出扰动特征识别结果。通过仿真实验得出,该方法能有效提取扰动特征,提取到的特征类型数量与实际类型数量一致;在噪声环境下,该方法依旧能够有效识别扰动特征,最低识别精度高达98.7%。

关键词： GA算法卷积神经网络分布式光伏低压台区电能质量扰动特征识别

Benefits and limitations of biochar for climate-smart agriculture:a review and case study from China

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Biochar 2023年第1期5卷 1319-1342页

作者： Xiaomeng Bo Zhiwei Zhang Jinyang Wang Shumin Guo Zhutao Li haiyan lin Yawen Huang Zhaoqiang Han Yakov Kuzyakov Jianwen Zou Key Laboratory of Green and Low-Carbon Agriculture in Southeastern China Ministry of Agriculture and Rural AffairsCollege of Resources and Environmental SciencesNanjing Agricultural UniversityNanjing 210095China Jiangsu Key Laboratory of Low Carbon Agriculture and GHGs Mitigation Jiangsu Collaborative Innovation Center for Solid Organic Waste Resource UtilizationNanjing 210095China Department of Soil Science of Temperate Ecosystems Department of Agricultural Soil ScienceUniversity of Gottingen37077 GottingenGermany Peoples Friendship University of Russia(RUDN University) 117198 MoscowRussia Institute of Environmental Sciences Kazan Federal University420049 KazanRussia

Biochar has gained significant attention in agricultural and environmental research over the last two *** comprehensive review evaluates the effects of biochar on soil organic carbon(SOC),emission of non-CO_(2) greenhouse gases,and crop yield,including related mechanisms and major influencing *** impacts of biochar on SOC,methane and nitrous oxide emissions,and crop yield are controlled by biochar and soil properties and management ***-temperature biochar produced from lignin-rich feedstocks may decrease methane and nitrous oxide emissions in acidic soils and strengthen long-term carbon sequestration due to its stable aromatic *** contrast,low-temperature biochar from manure may increase crop yield in low-fertility *** biochar to farmlands in China can increase SOC content by 1.9 Pg C and reduce methane and nitrous oxide emissions by 25 and 20 Mt CO_(2)-eq year^(−1),respectively,while increasing crop yields by 19%.Despite the increasing evidence of the positive effects of biochar,future research needs to explore the potential factors that could weaken or hinder its capacity to address climate change and secure crop *** conclude that biochar is not a universal solution for global cropland;however,targeted applications in fields,landscapes,or regional scales,especially in low fertility and sandy soils,could realize the benefits of biochar as a climate-smart measure.

关键词： Biochar Carbon sequestration Greenhouse gas Food security Mitigation potential

FRUCTOKINASE-LIKE PROTEIN 1 interacts with TRXz to regulate chloroplast development in rice

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Journal of Integrative Plant Biology 2018年第2期60卷 94-111页

作者： Lei He Sen Zhang Zhennan Qiu Juan Zhao Wendan Nie haiyan lin Zhengge Zhu Dali Zeng Qian Qian Li Zhu State Key Laboratory of Rice Biology China National Rice Research Institute Hebei Key Laboratory of Molecular and Cellular Biology Hebei Normal University

Chloroplast genes are transcribed by the plastidencoded RNA polymerase（PEP） or nucleus-encoded RNA polymerase. FRUCTOKINASE-LIKE PROTEINS（FLNs） are phosphofructokinase-B（Pfk B）-type carbohydrate kinases that act as part of the PEP complex; however, the molecular mechanisms underlying FLN activity in rice remain ***, we identified and characterized a heat-stress sensitive albino（hsa_1） mutant in rice. Map-based cloning revealed that HSA_1 encodes a putative OsFLN_2. Here, we further demonstrated that knockdown or knockout of the OsFLN_1, a close homolog of HSA_1/OsFLN_2, considerably inhibits chloroplast biogenesis and the fln_1 knockout mutants, created by clustered regularly interspaced short palindromic repeats（CRISPR） and CRISPR-associate protein_9, exhibit severe albino phenotype and seedling lethality. Moreover, OsFLN_1 localizes to the *** two-hybrid, pull-down and bimolecular fluorescencecomplementation experiments revealed that OsFLN_1 and HSA_1/OsFLN_2 interact with THIOREDOXINZ（OsTRXz） to regulate chloroplast development. In agreement with this,knockout of OsTRXz resulted in a similar albino and seedling lethality phenotype to that of the fln_1 mutants. Quantitative reverse transcription polymerase chain reaction and immunoblot analysis revealed that the transcription and translation of PEP-dependent genes were strongly inhibited in fln_1 and trxz mutants, indicating that loss of OsFLN_1, HSA_1/OsFLN_2, or OsTRXz function perturbs the stability of the transcriptionally active chromosome complex and PEP activity. These results show that OsFLN_1 and HSA_1/OsFLN_2 contribute to chloroplast biogenesis and plant growth.

关键词： FLN FRUCTOKINASE-LIKE PROTEIN 1 interacts with TRXz to regulate chloroplast development in rice HSA PEP

Autofocus by Lissajous scanning in time reversal optical scanning holography

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Chinese Optics Letters 2024年第8期22卷 13-20页

作者： Jie Liu haiyan Ou Hua Wang lin Peng Wei Shao Shenzhen Institute for Advanced Study University of Electronic Science and Technology of ChinaShenzhen 518000China School of Physics University of Electronic Science and Technology of ChinaChengdu 611731China Key Laboratory of Cognitive Radio and Information Processing Guilin University of Electronic TechnologyGuilin 541004China

In this Letter, an autofocusing method in optical scanning holography(OSH) system is proposed. By introducing Lissajous scanning into multiple signal classification(MUSIC) method in time-reversal(TR) OSH, the axial locations of the targets can be retrieved with better resolution and the peak prominence increases from 0.21 to 0.34. The feasibility of this method is confirmed by simulation as well as experiment.

关键词： digital holography Lissajous scanning image reconstruction axial localization

疏肝理气解郁方联合西药治疗卒中后抑郁临床研究

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新中医 2024年第18期56卷 50-54页

作者：徐晏雯徐勇明温晗陈芬芬王传刘林海燕杨铭张麟衢州市人民医院神经内科浙江衢州324000

目的:观察疏肝理气解郁方联合西药治疗卒中后抑郁的临床疗效及对T淋巴细胞亚群的影响。方法:选择2023年1—12月收治的卒中后抑郁患者104例,按随机数字表法分为治疗组、对照组各52例。对照组给予常规西药治疗,治疗组在对照组基础上加用... 详细信息

目的:观察疏肝理气解郁方联合西药治疗卒中后抑郁的临床疗效及对T淋巴细胞亚群的影响。方法:选择2023年1—12月收治的卒中后抑郁患者104例,按随机数字表法分为治疗组、对照组各52例。对照组给予常规西药治疗,治疗组在对照组基础上加用疏肝理气解郁方治疗,2组均治疗8周。比较2组治疗前后中医证候积分、抑郁症状评分[汉密尔顿抑郁量表(HAMD)评分、抑郁自评量表(SDS)评分]及T淋巴细胞亚群水平,并评估2组临床疗效及不良反应发生情况。结果:治疗组总有效率92.31%,高于对照组76.92%(P0.05)。结论:疏肝理气解郁方联合西药治疗卒中后抑郁效果良好,能够减轻患者抑郁症状,调节T淋巴细胞亚群水平,安全性较高。

关键词：卒中后抑郁疏肝理气解郁方汉密尔顿抑郁量表评分抑郁自评量表评分 T淋巴细胞亚群

Neuro-regenerative imidazole-functionalized GelMA hydrogel loaded with hAMSC and SDF-1α promote stem cell differentiation and repair focal brain injury

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Bioactive Materials 2021年第3期6卷 627-637页

作者： Yantao Zheng Gang Wu Limei Chen Ying Zhang Yuwei Luo Yong Zheng Fengjun Hu Tymor Forouzanfar haiyan lin Bin Liu Emergency Department Zhujiang HospitalSouthern Medical UniversityGuangzhouChina Department of Oral Implantology and Prosthetic Dentistry Academic Centre for Dentistry Amsterdam(ACTA)University of Amsterdam(UvA)and Vrije Universiteit Amsterdam(VU)AmsterdamNetherlands Department of Emergency Guangzhou Red Cross HospitalMedical CollegeJinan UniversityGuangzhou City510220China Rheumatology Department The Third Affiliated Hospital of Southern Medical UniversityGuangzhouChina Emergency Medicine Department Qingxin Section of Qingyuan People's HospitalQingyuanChina Institute of Information Technology Zhejiang Shuren UniversityHangzhouChina Department of Oral and Maxillofacial Surgery/Pathology Amsterdam UMC and Academic Center for Dentistry Amsterdam(ACTA)Vrije Universiteit AmsterdamAmsterdam Movement Sciencede Boelelaan1117AmsterdamNetherlands Savaid Stomatology School Hangzhou Medical CollegeHangzhouChina

Brain tissues that are severely damaged by traumatic brain injury(TBI)is hardly regenerated,which leads to a cavity or a repair with glial ***-cell therapy is one viable option to treat TBI-caused brain tissue damage,whose use is,whereas,limited by the low survival rate and differentiation efficiency of stem *** approach this problem,we developed an injectable hydrogel using imidazole groups-modified gelatin methacrylate(GelMA-imid).In addition,polydopamine(PDA)nanoparticles were used as carrier for stromal-cell derived factor-1(SDF-1α).GelMA-imid hydrogel loaded with PDA@SDF-1αnanoparticles and human amniotic mesenchymal stromal cells(hAMSCs)were injected into the damaged area in an in-vivo cryogenic injury model in *** hydrogel had low module and its average pore size was 204.61±41.41 nm,which were suitable for the migration,proliferation and differentiation of stem ***-vitro cell scratch and differentiation assays showed that the imidazole groups and SDF-1αcould promote the migration of hAMSCs to injury site and their differentiation into nerve *** highest amount of nissl body was detected in the group of GelMA-imid/SDF-1α/hAMSCs hydrogel in the in-vivo ***,histological analysis showed that GelMA-imid/SDF-1α/hAMSCs hydrogel could facilitate the regeneration of regenerate endogenous nerve *** summary,the GelMA-imid/SDF-1α/hAMSCs hydrogel promoted homing and differentiation of hAMSCs into nerve cells,and showed great application potential for the physiological recovery of TBI.

关键词： Injectable hydrogel Imidazole Stromal-cell derived factor-1(SDF-1α) Human amniotic mesenchymal stromal cells (hAMSCs) Brain injury

短切碳纤维分散方式及对纤维增强石膏基复合材料力学性能的影响

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新型建筑材料 2024年第6期51卷 72-77页

作者：郭炎飞刘博郅真真刘秋杰吴帆茹晓红林海燕洛阳理工学院材料科学与工程学院河南洛阳471023 河南科技大学材料科学与工程学院河南洛阳471023

采用H_(2)O_(2)和NaClO对短切碳纤维进行表面氧化处理,并采用PCE、HPMC以及超声对其进行分散处理,制备短切碳纤维增强石膏基复合材料,并对其力学性能进行研究。结果表明:经过氧化处理后,短切碳纤维表面亲水含氧官能团羟基和羰基含量增多... 详细信息

采用H_(2)O_(2)和NaClO对短切碳纤维进行表面氧化处理,并采用PCE、HPMC以及超声对其进行分散处理,制备短切碳纤维增强石膏基复合材料,并对其力学性能进行研究。结果表明:经过氧化处理后,短切碳纤维表面亲水含氧官能团羟基和羰基含量增多,表面粗糙度增大;氧化处理后的短切碳纤维在PCE溶液中分散效果最好;短切碳纤维的加入有效提高石膏硬化体的抗压强度,当掺1%采用PCE分散处理的6 mm短切碳纤维时,石膏硬化体强度最高,较未掺时提高72.4%,这是由于PCE在短切碳纤维表面的吸附性和PCE与石膏颗粒反应形成的空间位阻效应双重作用提高了短切碳纤维在石膏浆体中的分散性,进而提高了短切碳纤维增强石膏基复合材料的抗压强度。

关键词：短切碳纤维分散性表面氧化石膏基复合材料力学性能

GnRH Antagonist Protocol: Is It Optimal for All Patients of Different Ages Undergoing <i>In Vitro</i>Fertilization and Embryo Transfer?

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Advances in Sexual Medicine 2017年第4期7卷 153-160页

作者： Weijie Xing haiyan lin Qingxue Zhang Center for Reproductive Medicine The Third Affiliated Hospital of Sun Yat-sen University Guangzhou China Center for Reproductive Medicine Sun Yat-sen Memorial Hospital of Sun Yat-sen University Guangzhou China

Background: To assess the effect of these two protocols in patients of different ages. Methods: 1923 in vitro fertilization and embryo transfer (IVF-ET) cycles were divided into two groups: a GnRH-ant protocol group and GnRH-a long protocol group, and then every group were subdivided into four age ranges. The general materials and IVF outcomes were compared. Results: The incidence of OHSS fluctuated from 0% to 2.37% with GnRH-ant protocol, which was significantly lower than another (P P Conclusion: The antagonist protocol should be considered in patients with a high ovarian response (e.g., PCOS patients) to avoid OHSS. Older patients (>35 years) could be treated with the antagonist protocol.

关键词： GnRH Agonist GnRH Antagonist IVF-ET