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Nano Research 2019年第9期12卷 2318-2323页

作者： haixia Zhong Fanlu Meng Qi Zhang Kaihua Liu Xinbo Zhang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute cf Applied ChemistryChinese Academy of SciencesChangchun 130022China Key Laboratory of Automobile Materials Ministry of Education and College of Materials Science and EngineeringJilin UniversityChangchun 130012China

Carbon dioxide reduction(CO2RR)has become a promising way to address the energy and environmental crisis,of which the fundamental development of the optimal electrocatalysts is the crucial ***,we develop Fe and N doping porous carb on n ematosphere(FeNPCN)as an excellent CO2RR electrocatalyst in aqueous *** with the high conductivity,pore structure and abundant Fe and N doping,FeNPCN exhibits high catalytic activity with a high faradaic selectivity of CO(94%)and long-term ***,the ratio of CO and H2 can be changed by the applied potential for the different syngas related *** functional theory(DFT)calculation results also reveal that the excellent catalytic activity is likely attributed to C and N hybrid coordination with atomic Fe.

关键词： carbon dioxide reducti on electrocatalysis porous carbon carb on mon oxide metal/nitrogen dopi ng

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基于NDIR的甲烷气体传感器设计与测试

微处理机 2024年第3期45卷 39-42页

作者：王琛邢海霞李晓干大连理工大学集成电路学院大连116620

针对目前非分光红外CH4气体传感器灵敏度较低且响应时间较长等问题,设计一款基于光电导原理的CH4气体传感器。该传感器主要由PbSe光导型红外探测器、信号处理部分电路、光源驱动部分电路及光路气室组成,通过分析气体浓度与探测器输出信... 详细信息

针对目前非分光红外CH4气体传感器灵敏度较低且响应时间较长等问题,设计一款基于光电导原理的CH4气体传感器。该传感器主要由PbSe光导型红外探测器、信号处理部分电路、光源驱动部分电路及光路气室组成,通过分析气体浓度与探测器输出信号之间的关系,拟合浓度输出关系方程,以实现检测功能。通过实验,在室温下对不同浓度气体进行检测,结果表明该传感器的输出误差、最低检测限、最低响应时间等参数表现良好,可在1000 cm^(3)/m^(3)范围内对气体实现有效测量。

关键词：光导型探测器浓度标定非分光红外技术

Three-dimensional interconnected Ni（Fe）OxHy nanosheets on stainless steel mesh as a robust integrated oxygen evolution electrode

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Nano Research 2018年第3期11卷 1294-1300页

作者： Qi Zhang haixia Zhong Fanlu Meng Di Bao Xinbo Zhang Xiaolin wei Hunan Key Laboratory for Micro-Nano Energy Materials and Device Department of Physics Xiangtan University Xiangtan 411105 China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China

The development of an electrocatalyst based on abundant elements for the oxygen evolution reaction （OER） is important for water splitting associated with renewable energy sources. In this study, we develop an interconnected Ni（Fe）OxHy nanosheet array on a stainless steel mesh （SSNNi） as an integrated OER electrode, without using any polymer binder. Benefiting from the well- defined three-dimensional （3D） architecture with highly exposed surface area, intimate contact between the active species and conductive substrate improved electron and mass transport capacity, facilitated electrolyte penetration, and improved mechanical stability. The SSNNi electrode also has excellent OER performance, including low overpotential, a small Tafel slope, and long-term durability in the alkaline electrolyte, making it one of the most promising OER electrodes developed.

关键词： oxygen evolution reaction three-dimensional (3D)architecture stainless steel mesh (SSNNi) integrated oxygenevolution electrode

间充质干细胞对实验性自身免疫性脑脊髓炎小鼠铁死亡的影响

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山东大学学报（医学版） 2024年第6期62卷 1-8页

作者：刘海霞皇甫莎莎桑晓玉崔东清毕建忠王萍山东大学第二医院神经内科山东济南250033

目的探讨间充质干细胞(mesenchymal stem cells,MSCs)治疗对实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,EAE)小鼠铁死亡状况及关键调控蛋白表达的影响。方法记录每日小鼠体质量和行为表现,切片染色观察小鼠... 详细信息

目的探讨间充质干细胞(mesenchymal stem cells,MSCs)治疗对实验性自身免疫性脑脊髓炎(experimental autoimmune encephalomyelitis,EAE)小鼠铁死亡状况及关键调控蛋白表达的影响。方法记录每日小鼠体质量和行为表现,切片染色观察小鼠脊髓中炎症及脱髓鞘情况。通过检测还原型谷胱甘肽还原酶(reduced glutathione,GSH)、丙二醛(malondialdehyde,MDA)及总超氧化物歧化酶(total superoxide dismutase,T-SOD)观察小鼠组织中铁死亡状况,并检测转铁蛋白受体-1(transferrin receptor 1,TFR1)、酰基辅酶A合酶-4(acyl-CoA synthetase long-chain family 4,ACSL4)、谷胱甘肽过氧化酶-4(glutathione peroxidase 4,GPX4)及铁死亡抑制蛋白1(ferroptosis suppressor protein,FSP1)等调控蛋白的表达。结果MSCs可以有效改善EAE小鼠体质量下降和症状表现。病理水平上,MSCs注射可以改善小鼠脊髓中炎细胞浸润及脱髓鞘。MSCs注射后,EAE小鼠脊髓和脑GSH含量升高(P<0.01,P<0.05)、脊髓T-SOD活力升高(P<0.01),脑中MDA含量下降(P<0.05)。MSCs治疗可以降低EAE小鼠脊髓和脑中TFR1(P<0.05,P<0.01)、ACSL4蛋白表达(P<0.05,P<0.001),提高脊髓和脑中FSP1蛋白表达(P均<0.05)和脑中GPX4蛋白表达(P<0.05)。结论MSCs通过调节铁代谢、脂代谢和促进活性氧清除来抑制EAE小鼠中铁死亡,发挥治疗作用。

关键词：多发性硬化实验性自身免疫性脑脊髓炎间充质干细胞铁死亡铁代谢

Fluid Inclusions and Isotope Geochemistry of the Emba Derho and the Debarwa VMS Deposits, Asmara District, Eritrea

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Acta Geologica Sinica(English Edition) 2016年第4期90卷 1547-1548页

作者： XU Jiuhua CHENG Xihui CHU haixia XIAO Xing ZHANG Hui University of Science and Technology Beijing Beijing 100083 China

Objective Recent exploration indicates several localities with significant gold, copper, and zinc resource potential in the Asmara district, Eritrea, including the Emba Derho and Debarwa volcanic-associated massive sulfide deposits. These deposits are hosted by the Neoproterozoic metamorphic volcanic rocks of Asmara green stone belt, which strike NNW-SSE and are 200 km long and 5-20 km wide, and the mineralization is often associated with the altered and deformed rocks. The Emba Derho deposit, located 12 km northwest of Asmara （Fig. la）, the capital of Eritrea, is the largest Cu-Zn-Au VMS deposit in the Asmara metallogeny belt. It is estimated that the Emba Derho deposit of the Asmara project contains total reserves of 49.8~106 tons of copper ores and 16.8~106 tons of zinc ores. The gold grade of this deposit is about 0.3 lg/t. The Debarwa deposit, situated 26 km southwest of Asmara, has similar ore features with the Emba Derho deposit.

关键词： Fluid Inclusions and Isotope Geochemistry of the Emba Derho and the Debarwa VMS Deposits,Asmara District,Eritrea SRK VMS

Anomaly Detection of Industrial Control Systems Based on Transfer Learning

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Tsinghua Science and Technology 2021年第6期26卷 821-832页

作者： Weiping Wang Zhaorong Wang Zhanfan Zhou haixia Deng Weiliang Zhao Chunyang Wang Yongzhen Guo School of Computer and Communication Engineering the Beijing Key Laboratory of Knowledge Engineering for Materials Scienceand the Institute of Artificial IntelligenceUniversity of Science and Technology BeijingBeijing 100083China Shunde Graduate School University of Science and Technology BeijingGuangzhou 528399China School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing 100083China School of Mechanical Engineering University of Science and Technology BeijingBeijing 100083China Donlinks School of Economics and Management University of Science and Technology Beijing Beijing 100083China School of Automation Beijing Institute of TechnologyBeijing 100081 China Software Testing Center Beijing 100048China.

Industrial Control Systems(ICSs)are the lifeline of a ***,the anomaly detection of ICS traffic is an important *** paper proposes a model based on a deep residual Convolution Neural Network(CNN)to prevent gradient explosion or gradient disappearance and guarantee *** developed methodology addresses two limitations:most traditional machine learning methods can only detect known network attacks and deep learning algorithms require a long time to *** utilization of transfer learning under the modification of the existing residual CNN structure guarantees the detection of unknown ***-dimensional ICS flow data are converted into two-dimensional grayscale images to take full advantage of the features of *** show that the proposed method achieves a high score and solves the time problem associated with deep learning model *** model can give reliable predictions for unknown or differently distributed abnormal data through short-term ***,the proposed model ensures the safety of ICSs and verifies the feasibility of transfer learning for ICS anomaly detection.

关键词： anomaly detection transfer learning deep learning Industrial Control System(ICS)

血清lncRNA DUXAP8及miR-24-3p在子痫前期诊断及妊娠结局评估中的价值

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医学研究与战创伤救治 2024年第2期37卷 155-160页

作者：高海侠高京京张晓月司凡刘晓铮刘双双承德市中心医院妇儿院区产科承德067000

目的分析血清长非编码RNA双同源盒A伪基因8(lncRNA DUXAP8),微小RNA(miR)-24-3p在子痫前期(PE诊断及妊娠结局评估中的价值。方法选取2019年3月至2022年9月承德市中心医院妇儿院区产科124例PE患者为PE组,同期健康孕妇124例为对照组。根... 详细信息

目的分析血清长非编码RNA双同源盒A伪基因8(lncRNA DUXAP8),微小RNA(miR)-24-3p在子痫前期(PE诊断及妊娠结局评估中的价值。方法选取2019年3月至2022年9月承德市中心医院妇儿院区产科124例PE患者为PE组,同期健康孕妇124例为对照组。根据妊娠结局分为不良组27例和良好组97例。均采用qRT-PCR法测定血清lncRNA DUXAP8、miR-24-3p水平。采用多因素Logistic回归分析PE孕妇妊娠结局影响因素。采用ROC曲线分析血清lncRNA DUXAP8、miR-24-3p水平诊断PE及预后的价值。结果PE组血清lncRNA DUXAP8水平低于对照组,miR-24-3p水平高于对照组(P<0.05)。TargetScanHuman网站预测显示,lncRNA DUXAP8与miR-24-3p间可能存在靶向关系。相关性分析表明,lncRNA DUXAP8与miR-24-3p呈负相关(r=-0.471,P<0.001)。血清lncRNA DUXAP8、miR-24-3p联合诊断PE的AUC显著高于单独诊断(Z_(lncRNA DUXAP8-联合)=3.285,P=0.001;Z_(miR-24-3p-联合)=3.020,P=0.003),联合诊断的敏感性为92.74%,特异性为72.31%。良好组孕妇血清lncRNA DUXAP8水平高于不良组,miR-24-3p水平低于不良组(P<0.05)。良好组孕妇收缩压、舒张压、产前血糖、血红蛋白、24 h尿蛋白、白细胞计数、LDH低于不良组,血小板计数、血清白蛋白高于不良组(P<0.05)。lncRNA DUXAP8是PE孕妇妊娠结局不良保护因素,miR-24-3p是危险因素(P<0.05)。血清lncRNA DUXAP8、miR-24-3p联合诊断PE孕妇妊娠结局的AUC显著高于单独诊断(Z_(lncRNA DUXAP8-联合)=2.113,P=0.035,Z_(miR-24-3p-联合)=3.033,P=0.002),联合诊断的敏感性为88.89%,特异性为80.41%。结论PE孕妇lncRNA DUXAP8水平降低,miR-24-3p水平升高,可能与PE的发生和孕妇妊娠结局相关。

关键词：长非编码RNA双同源盒A伪基因8 微小RNA-24-3p 子痫前期妊娠结局

热浪频次及间隔时间对闽楠和木荷苗木水力结构和非结构性碳水化合物的影响

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生态学报 2024年第3期44卷 1251-1263页

作者：张子雷余海霞曲鲁平汤行昊王浩王朝昭刘南王艺璇邵长亮董刚福建农林大学林学院福州350002 福建省林业科学研究院福州350002 中国农业科学院农业资源与农业区划研究所北京100081 山西大学生命科学学院太原030006

近年来亚热带地区极端气候事件热浪发生频率增加,热浪频次及间隔时间的变化使热浪发生的模式及其对植物的胁迫方式更加多样化。高频热浪不仅通过热胁迫影响植物的碳固持速率,还会间接形成水分胁迫造成植物水力结构发生障碍,影响碳水化... 详细信息

近年来亚热带地区极端气候事件热浪发生频率增加,热浪频次及间隔时间的变化使热浪发生的模式及其对植物的胁迫方式更加多样化。高频热浪不仅通过热胁迫影响植物的碳固持速率,还会间接形成水分胁迫造成植物水力结构发生障碍,影响碳水化合物的运输。然而,目前亚热带树木水力结构和非结构性碳水化合物(NSC)对复杂热浪的模式的响应仍不明确。以亚热带主要阔叶树种闽楠(Phoebe bournei)和木荷(Schima superba)苗木为研究对象进行了热浪模拟试验,关注不同热浪频次(单次,两次)及重复热浪间隔时间(短间隔、中间隔、长间隔)对苗木茎部水力结构特征及NSC的影响,使用冲洗法测定水力结构中的导水率(Kh)、最大导水率(K_(max))、比导率(K_(s))、木质部栓塞百分数(PLC),使用蒽酮-硫酸比色法测定茎段非结构性碳水化合物含量。结果表明,(1)闽楠和木荷的水力结构和非结构性碳水化合物在树种间存在显著差异;(2)不同热浪频次对闽楠和木荷的K_(max)和PLC影响存在显著差异;(3)重复热浪间隔时间变长,木荷茎栓塞减轻,而闽楠茎栓塞增加,且植株栓塞越严重,茎NSC含量越少。总体上,闽楠的水力传输系统对热浪抗性较弱,在热浪后栓塞严重,导水率下降且无法完全恢复,且NSC含量与栓塞程度相关性较弱;而木荷水力传输系统抗性较强,在热浪后导水能力可能恢复至未受干扰水平,且其恢复程度与NSC含量紧密相关。该研究结果表明,高频热浪的发生会显著影响闽楠和木荷苗木茎部的导水能力,且不同间隔时间的重复热浪事件对植物水力结构的影响存在差异性,并且两个亚热带阔叶树种对热浪伴随的高温和水分胁迫的耐受性和耐受机制存在差异。

关键词：热浪频次间隔时间闽楠木荷水力结构非结构性碳水化合物

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A Smart Wearable Ring Device for Sensing Hand Tremor of Parkinson’s Patients

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Computer Modeling in Engineering & Sciences 2021年第3期126卷 1217-1238页

作者： haixia Yang Yixian Shen Wei Zhuang Chunming Gao Dong Dai Weigong Zhang School of Instrument Science and Engineering Southeast UniversityNanjing210096China School of Computer and Software Nanjing University of Information Science and TechnologyNanjing210044China School of Engineering and Technology University of WashingtonTacoma98402USA School of Cyber Science and Engineering Southeast UniversityNanjing210096China

Parkinson’s disease(PD)is a very common neurodegenerative disease that occurs mostly in the *** are many main clinical manifestations of PD,such as tremor,bradykinesia,muscle rigidity,*** on the current research on PD,the accurate and convenient detection of early symptoms is the key to detect *** the development of microelectronic and sensor technology,it is much easier to measure the barely noticeable tremor in just one hand for the early detection of Parkinson’s *** this paper,we present a smart wearable device for detecting hand tremor,in which MPU6050(MIDI Processing Unit)consisting of a 3-axis gyroscope and a 3-axis accelerometer is used to collect acceleration and angular velocity of *** analyzing the time of specific finger movements,we successfully recognized the tremor signals with high ***,with Bluetooth 4.0(Bluetooth Low Energy,BLE)and networking terminal ability,tremor data can be transferred to a monitoring device in real time with extremely lowenergy *** experimental results have shown that the proposed device(smart ring)is convenient for long-term tremor detection which is vital for early detection and treatment for Parkinson’s disease.

关键词： Parkinson’s disease tremor detection IMU sensor MPU6050 BLE

Lifetime Prediction of Wind Turbine Blade Based on Full-Scale Fatigue Testing

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Journal of Shanghai Jiaotong university(Science) 2020年第6期25卷 755-761页

作者： KOU haixia AN Zongwen MA Qiang GUO Xu School of Mechanical and Electronical Engineering Lanzhou University of TechnologyLanzhou 730050China

In order to predict the lifetime of products appropriately with long lifetime and high reliability,the accelerated degradation testing(ADT)has been *** wind turbine blade is one of the most important components in wind turbine *** fatigue cycle is very long in practice.A full-scale fatigue testing is usually used to verify the design of a new *** general,the full-scale fatigue testing of blade is accelerated on the basis of the damage equivalent *** the full-scale fatigue test ing,blade is subjected to higher testing load than normal operat ing conditions;consequently,the performance degradation of the blade is hastened over *** full-scale fatigue testing of blade is regarded as a special *** to the fatigue failure criterion,we choose blade stiffness as the characteristic quantity of the blade performance,and propose an accelerated model(AM)for blade on the basis of the theories of ***,degradation path of the blade stiffness is modeled by using Gamma ***,the lifet ime prediction of full-scale megawatt(MW)blade is conducted by combining the proposed AM and blade stiffness degradation *** prediction results prove the reasonability and validity of this *** can supply a new approach to predict the lifetime of the full-scale MW blade.

关键词： composite wind turbine blade accelerated degradation testing(ADT) acelerated model(AM) full-scale fatigue testing blade stiffness lifet ime prediction