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现代食品 2024年第4期30卷 104-109页

作者：赵品瑶陈巧灵王海浪王稼辰周岭宜宾学院质量管理与检验检测学部四川宜宾644000 宜宾学院农食产品标准化与检验检测四川省高等学校工程研究中心四川宜宾644000 宜宾学院固态发酵资源利用四川省重点实验室四川宜宾644000

近年,随着微生物发酵工艺的成熟,利用发酵技术生产白酒糟蛋白,成为饲料资源开发领域的研究重点。因此,本文分析了酒糟的营养价值及资源利用现状,探讨了不同菌种组合对发酵白酒糟的影响,以供参考。

关键词：微生物发酵白酒糟饲料

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Enriched photosensitizer for deep-seated-tumor photodynamic therapy

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Photonics Research 2024年第5期12卷 1024-1035页

作者： HONGRUI SHAN XUEQIAN wang QIHENG WEI hailang DAI XIANFENG CHEN State Key Laboratory on Fiber Optic Local Area Communication Networks and Advanced Optical Communication Systems Department of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Metal Matrix Composites Shanghai Key Laboratory for Molecular Engineering of Chiral DrugsSchool of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China Collaborative Innovation Center of Light Manipulations and Applications Shandong Normal UniversityJinan 250358China

Photodynamic therapy(PDT)is an innovative approach that utilizes photochemical reactions for non-invasive disease *** PDT is limited by the low penetration depth of visible light required for ***,we employed upconversion nanoparticles(UCNPs)to extend the activation wavelength of photosensitizers into the infrared range,enabling a treatment depth of over 10 ***,we also used the abundant amino groups of branched polyethyleneimine(PEI)with spatial structure to enhance the loading capacity of protoporphyrin(PPIX),and we ultimately improved skin tumor clearance ***,we achieved tumor-specific treatment by utilizing folic acid(FA)targeting and active enrichment of *** to cellular experimental results,we demonstrated the remarkable reactive oxygen species generation capability of the material and ultra-low dark ***,we investigated the apoptosis mechanism and demonstrated that the synthesized nanoparticle stimulates the up-regulation of apoptosis-associated proteins Bax/Bcl-2 and Cyto *** in vivo experiments involving intravenous injection in mouse tails,we investigated the anticancer efficacy of the nanoparticle,confirming its excellent PDT *** research provides a promising avenue for future non-invasive treatment of deep-seated tumors,offering a method for the treatment and management of specific cancers.

关键词： treatment utilize utilizing

Effect of fatigue load on the bending tribo-corrosion-fatigue behaviors between the main cable wires

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Friction 2024年第7期12卷 1512-1531页

作者： Bo wang Dagang wang Jihong YE Liang TANG hailang CHONG Wei XU Xinxin ZHANG Jianhao CHEN Haiyan DENG Jie ZHANG Guowen YAO Magd Abdel WAHAB School of Mechatronic Engineering China University of Mining and TechnologyXuzhou 221116China Xuzhou Key Laboratory for Fire Safety of Engineering Structures China University of Mining and TechnologyXuzhou 221116China National Wire Rope Quality Inspection Center Nantong Product Quality Supervision and Inspection InstituteNantong 226011China Jiangsu Langshan Wire Rope Co. Ltd.Nantong 226003China School of Mechatronic Engineering Southwest Petroleum UniversityChengdu 610500China School of Civil Engineering Chongqing Jiaotong UniversityChongqing 400074China Soete Laboratory Faculty of Engineering and ArchitectureGhent UniversityZwijnaarde B-9052Belgium

The main cable bent around the saddle of the suspension bridge is subjected to the wind,the vehicle,the bridge’s own weight and the corrosive *** coupling of the three loads and the environments causes the friction,the corrosion,and the fatigue(tribo-corrosion-fatigue)among the wires inside the main *** this paper,a wire bending tribo-corrosion-fatigue test rig was designed and *** effect of fatigue load on the bending friction behaviors between the cable wires in ultrapure water and 3.5%NaCl solution was *** tribological properties and electrochemical corrosion behaviors under different fatigue loading ranges were *** tribo-corrosion-fatigue interaction between the cable wires was quantitatively characterized,and the mechanism of the interaction was *** results demonstrate that the increasing fatigue load exacerbates the coupling damage of the cable wires attributed to the enhanced *** findings carry theoretical importance when assessing the main cable’s deterioration and the load-bearing safety of a suspension bridge.

关键词： bending tribo-corrosion-fatigue interaction parallel steel wires fatigue load

Multi-omics analyses of 398 foxtail millet accessions reveal genomic regions associated with domestication,metabolite traits,and antiinflammatory effects

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Molecular Plant 2022年第8期15卷 1367-1383页

作者： Xukai Li Jianhua Gao Jingyi Song Kai Guo Siyu Hou Xingchun wang Qiang He Yanyan Zhang Yakun Zhang Yulu Yang Jiaoyan Tang hailang wang Staffan Persson Mingquan Huang Lishuai Xu Linlin Zhong Dongqin Li Yongming Liu Hua Wu Xianmin Diao Peng Chen Xiaowen wang Yuanhuai Han Shanxi Key Laboratory of Minor Crop Germplasm Innovation and Molecular Breeding College of Life SciencesShanxi Agricultural UniversityTaiguChina Key Laboratory of Brewing Molecular Engineering of China Light Industry Beijing Technology and Business UniversityBeijingChina Department of Neurology University of MichiganAnn ArborMIUSA Shanxi Key Laboratory of Minor Crop Germplasm Innovation and Molecular Breeding College of AgricultureShanxi Agricultural UniversityTaiguChina Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijingChina Colllege of Plant Science and Technology Huazhong Agricultural UniversityWuhanChina Copenhagen Plant Science Centre Department of Plant&Environmental SciencesUniversity of CopenhagenFrederiksberg CDenmark Joint International Research Laboratory of Metabolic and Developmental Sciences School of Life Sciences and BiotechnologyShanghai Jiao Tong UniversityMinhangShanghai 200240China College of Resources and Environment Shanxi Agricultural UniversityTaiguChina College of Horticulture and Forestry Sciences Huazhong Agricultural UniversityWuhanChina National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhanChina Grandomics Biosciences Company Limited BeijingChina College of Food Science and Engineering Shanxi Agricultural UniversityTaiguChina

Foxtail millet(Setaria italica),which was domesticatedfromthewild speciesgreenfoxtail(Setaria viridis),isa richsource of phytonutrientsfor *** evaluate how breeding changed themetabolome offoxtail millet grains,we generated and analyzed the datasets encompassing the genomes,transcriptomes,metabolomes,and anti-inflammatory indices from 398 foxtail millet *** identified hundreds of common variants that influence numerous secondary *** observed tremendous differences in natural variations of the metabolites and their underlying genetic architectures between distinct sub-groups of foxtail ***,we found that the selection of the gene alleles associated with yellow grains led to altered profiles of metabolites such as carotenoids and endogenous *** CRiSPR-mediated genome editing wevalidated the function of PHYTOENE SYNTHASE1(PSY1)gene in affecting milletgrain colorand ***,our in vitro cell inflammation assays showed that 83 metabolites in millet grains have anti-inflammatory *** together,ourmulti-omics study illustrates how the breeding history of foxtail millet has shaped its metabolite *** datasets we generated in this study also provide important resources for further understanding how millet grain quality is affected by different metabolites,laying the foundations for future millet genetic research and metabolome-assisted improvement.

关键词： foxtail millet multi-omics,genetic association metabolome transcriptome anti-inflammatory effects

不同剂量右美托咪定对妇科手术麻醉患者血流动力学的影响及麻醉镇静效果

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首都食品与医药 2022年第22期29卷 67-69页

作者：王海浪江南大学附属医院江苏无锡214000

目的探讨不同剂量右美托咪定对妇科手术麻醉患者血流动力学的影响及麻醉镇静效果.方法选取江南大学附属医院妇科手术患者共计120例,研究时间为2021年2月-2022年4月,采用随机数字表法分组,对照组60例术中给予等容量生理盐水,研究组60... 详细信息

目的探讨不同剂量右美托咪定对妇科手术麻醉患者血流动力学的影响及麻醉镇静效果.方法选取江南大学附属医院妇科手术患者共计120例,研究时间为2021年2月-2022年4月,采用随机数字表法分组,对照组60例术中给予等容量生理盐水,研究组60例术中则给予右美托咪定,对两组麻醉效果、血流动力学变化等探讨与分析.结果研究组术中不同时间点丙泊酚血浆靶浓度低于对照组(P0.05);T2-T4研究组血流动力学指标明显低于对照组(P0.05);研究组T3时应激反应低于对照组(P0.05).结论妇科手术麻醉中,麻醉诱导前右美托咪定静脉输注1.0μg/kg,随后持续输注0.5μg/kg.可稳定术中患者血流动力学,减少应激反应,控制丙泊酚使用量,不良反应少,临床价值明确.

关键词：妇科手术右美托咪定血流动力学应激反应不良反应

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柴油发动机废气再循环控制策略优化研究

中国工程机械学报 2024年第2期22卷 196-201页

作者：王禹潘明章桑海浪广西大学机械工程学院广西南宁530004 广西玉柴机器股份有限公司广西南宁530007

针对柴油发动机在瞬态工况下废气再循环(EGR)控制响应慢和稳定性差问题,在对进气量控制的基础上,提出一种基于最小二乘向量机(LSSVM)的EGR目标开度预测模型。通过改进的平衡优化器算法(EO)来调整LSSVM的正则化参数和带宽,提高了模型预... 详细信息

针对柴油发动机在瞬态工况下废气再循环(EGR)控制响应慢和稳定性差问题,在对进气量控制的基础上,提出一种基于最小二乘向量机(LSSVM)的EGR目标开度预测模型。通过改进的平衡优化器算法(EO)来调整LSSVM的正则化参数和带宽,提高了模型预测性能,并分别建立了基于PLEO-LSSVM的EGR目标开度控制模型和基于PLEO-LSSVM的EGR双闭环控制模型。为验证提出的模型在瞬态工况下的性能,通过Simulink对提出的模型在定转速变扭矩和定扭矩变转速2种瞬态工况下进行模拟仿真与实验分析。仿真结果表明:提出的EGR目标开度控制模型和双闭环控制模型在瞬态工况下响应速度和稳定性上有更好的表现。其中,在定转速变扭矩和定扭矩变转速工况下,与传统的组合控制相比,提出的EGR目标开度控制模型响应速度分别快0.85%和3.64%,振幅分别小34.9%和12.1%。与现有的EGR双闭环控制相比,PLEO-LSSVM双闭环控制在定转速变扭矩工况下1.6~2.3 s时间内,响应速度快5.26%,振幅小31.7%,在4.5~5.5 s时间内,响应速度快5.5%,振幅小40.81%。在定扭矩变转速工况下6.7~7.3 s时间内,PLEO-LSSVM双闭环控制响应速度快2.17%,振幅小57.9%,在11.85~12.2 s时间内,响应速度快7.14%,振幅小60.9%。

关键词：柴油发动机 NO_x 废气再循环最小二乘向量机预测

tRNA核苷修饰基因在水稻生长发育和逆境调控方面的作用研究（英文）

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tRNA核苷修饰基因在水稻生长发育和逆境调控方面的作用研究（英文...

基于PEGASIS的无线传感器网络路由协议改进

第十九届中国作物学会学术年会

作者： Xiaoqi Zhou Xue Liu hailang wang Xiaoqing Yao Zhengyi Lv Peng Chen Colleage of Plant Science and Technology Huazhong Agricultural University

Modified nucleosides are prevelant in tRNAs from all kingdoms of life. So far more than 160 types of modified nucleosides are found in RNA molecules, tRNAs are the most heavily modified with more than 100 modifications present on different locations. One of the major modification is methylation, which requires methyl-transferase acting on different substrates with unique sequence-specificity. Compare to other kingdoms, tRNA modification and modification genes in plants, especially in crop species, have not been well documented. The present studies suggest that, 1) plant contains similar amounts of modified nucleosides on tRNA molecules both in cytoplasm and in mitochondria or chloroplast;2) defects in tRNA modification capacity can impair plant vegetative and/or reproductive growth;3) stress conditions can lead to changes on tRNA modification profiles, and vice versa. Based on these findings, we have used CRISPR technology to study the function of rice candidate genes potentially involved in tRNA modifications such as m1 G, m7 G and m2 G. Rice materials with up-or down-regulation on unique nucleoside methylations were affected for agronomic traits and stress tolerance. We will use proteomics and metabolomics data, together with the modomics profiles, to understand how certain tRNA nucleoside modifications led to changes on rice stress tolerance.

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计算机工程 2022年第12期48卷 165-171,179页

作者：王海浪张玲华南京邮电大学通信与信息工程学院南京210023 南京邮电大学江苏省通信与网络技术工程研究中心南京210023

传感器信息系统能量高效聚集(PEGASIS)协议是无线传感器网络中经典的分簇协议,由于实现简单得以广泛应用,但该协议中头节点的轮流当选策略和网络按照贪心算法成链的方法容易导致整个网络的能量消耗不均匀、节点死亡时间较早、网络延迟... 详细信息

传感器信息系统能量高效聚集(PEGASIS)协议是无线传感器网络中经典的分簇协议,由于实现简单得以广泛应用,但该协议中头节点的轮流当选策略和网络按照贪心算法成链的方法容易导致整个网络的能量消耗不均匀、节点死亡时间较早、网络延迟较大等问题。提出一种基于PEGASIS的剩余能量距离分区(PEGASIS-REDP)协议,在网络建立连接阶段对整个网络区域进行分区优化,在节点密度不变的情况下缩短差链距离。在头节点选取阶段,将节点剩余能量、区域内平均能量、距离基站的距离等多个因素作为判断头节点当选的条件,大幅减少头节点的更换次数。借助MATLAB软件仿真出PEGASIS-REDP协议建立网络的过程、在不同轮数下节点存活情况和头节点的选取情况,并在相同的实验条件下,针对不同路由协议在网络延迟、能量损耗和生命周期方面进行对比分析。实验结果表明,PEGASIS-REDP协议的网络生命周期相比于PEGASIS协议延长了19.6%,在均衡网络能耗和降低网络延时方面表现更好。

关键词：无线传感器网络传感器信息系统能量高效聚集协议分区剩余能量距离因子

S100钙结合蛋白A12在炎症性肠病中的研究进展

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胃肠病学 2012年第1期17卷 50-52页

作者：王海浪王巧民安徽医科大学附属安徽省立医院消化内科 230001

S100钙结合蛋白A12(S100A12)是近年发现的S100蛋白家族成员,主要来源于中性粒细胞,具有促炎、调节免疫、抗微生物、参与信号转导等多种生物学功能,在多种炎症情况下表达明显增加。近年研究发现,炎症性肠病(IBD)患者的肠黏膜、血液和粪便... 详细信息

S100钙结合蛋白A12(S100A12)是近年发现的S100蛋白家族成员,主要来源于中性粒细胞,具有促炎、调节免疫、抗微生物、参与信号转导等多种生物学功能,在多种炎症情况下表达明显增加。近年研究发现,炎症性肠病(IBD)患者的肠黏膜、血液和粪便S100A12含量均明显升高,由此提示其可作为本病诊断和鉴别诊断的指标之一,且可能在预测疾病活动度和治疗效果等方面具有重要作用。本文就S100A12在IBD中的研究进展作一综述。

关键词：钙结合蛋白质类炎症性肠病肠黏膜血液粪便

基于无人机低空遥感数据的时序动态生物量计算研究

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森林工程 2024年第1期40卷 17-25页

作者：张海浪廉旭刚王镭学高宇璐石力帆李宇太原理工大学矿业工程学院山西太原030024

为解决林分自然生长和人工剪伐修枝引起的单木特征参数变化所造成的生物量变化问题,采用地基激光雷达数据(TLS)和无人机激光雷达数据(UAV-LS)为数据源,通过单木分割的方法,以地基激光雷达数据提供的高精度数字高程模型为基础,提升无人... 详细信息

为解决林分自然生长和人工剪伐修枝引起的单木特征参数变化所造成的生物量变化问题,采用地基激光雷达数据(TLS)和无人机激光雷达数据(UAV-LS)为数据源,通过单木分割的方法,以地基激光雷达数据提供的高精度数字高程模型为基础,提升无人机激光雷达数据的单木召回率;基于无人机激光雷达数据进行单木树高的提取及一致性评定,通过优化的生物量模型,利用树高参数计算2022年和2023年各树种单木生物量。结果表明,联合地面激光雷达数据可以将无人机激光雷达数据的单木召回率从60.0%提升至73.1%;对2022年、2023年树高参数提取得到近两年树木自然生长、修剪状况;对树高一致性评定得到一致性相关系数(Concordance correlation coefficient,CCC)为0.98,均方根误差(RMSE)为1.12 m;对生物量计算得到近两年各树种单木生物量、林分生物量,2022年、2023年单位面积生物量分别为77.39、81.56 t/hm^(2)。研究证实在研究区通过无人机低空遥感数据获取树高时序动态计算各树种单木生物量可行,可以掌握林分自然生长和人工修剪引起的生物量变化。

关键词： TLS UAV-LS 树高生物量无人机