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Nonconforming H^1-Galerkin Mixed FEM for Sobolev Equations on Anisotropic Meshes

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Acta Mathematicae Applicatae Sinica 2009年第2期25卷 335-344页

作者： Dong-yang Shi hai-hong wang Department of Mathematics Zhengzhou University Zhengzhou 450052 China

A nonconforming H^1-Calerkin mixed finite element method is analyzed for Sobolev equations on anisotropic meshes. The error estimates are obtained without using Ritz-Volterra projection.

关键词： Nonconforming H^1-Galerkin mixed finite element method Sobolev equations anisotropic meshes,error estimates

On the Station-Keeping and Control of the World Space Observatory/Ultraviolet

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Chinese Journal of Astronomy and Astrophysics 2006年第3期6卷 372-378页

作者： Xi-Yun Hou hai-hong wang Lin Liu Department of Astronomy Nanjing University Nanjing 210093 Institute of Space Enviromnent and Astronautics Nanjing University Nanjing 210093

Collinear libration points play an important role in deep space exploration because of their special positions and dynamical characteristics. Since motion around them is unstable, we need to control the spacecraft if we wish to keep them around such a libration point for a long time. Here we propose a continuous low-thrust control strategy, illustrated with numerical simulations combined with the orbit design and control of the World Space Observatory/UltraViolet （WSO/UV）.

关键词： celestial mechanics - WSO/UV - low thrust

Synthesis and Herbicidal Activity of Novel Sulfonylureas Containing Thiadiazol Moiety

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Chemical Research in Chinese Universities 2008年第1期24卷 32-35页

作者： GUO Wan-cheng LIU Xing-hai LI Yong-hong wang Su-hua LI Zheng-ming Institute of Elemento-Organic Chemistry State Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin 300071 P. R. China

Thirteen novel sulfonylureas containing thiadiazole moiety were synthesized in a two-step reaction. Their structures were determined using IR, ^1H NMR, HRFTMS, and elemental analysis. Herbicidal activities of these compounds were determined in the green house bio-assay. The results show that four compounds among them exhibit some activity toward four tested herbs.

关键词： Sulfonylurea Synthesis Herbicidal activity

Strategies and challenges in treatment of varicose veins and venous insufficiency

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World Journal of Clinical Cases 2022年第18期10卷 5946-5956页

作者： Rong-Ding Gao Song-Yi Qian hai-hong wang Yong-Sheng Liu Shi-Yan Ren Department of Laser and Vascular Surgery Aviation General HospitalChina Medical UniversityBeijing 100012China Department of Cardiac Surgery Zhongshan Hospital(Xiamen Brach)Fudan UniversityXiamen 361015Fujian ProvinceChina Department of Peripheral Vascular Disease The Affiliated Hospital of Shanxi University of Chinese MedicineTaiyuan 030024Shanxi ProvinceChina Department of Dermatology Aviation General HospitalChina Medical UniversityBeijing 100012China

Patients with varicose veins can be treated with conservative or surgical approaches based on the clinical conditions and patient *** the recent decade,the recommendations for managing symptomatic varicose veins have changed dramatically due to the rise of minimally invasive endovascular *** literature was systematically searched on Medline without language *** papers on the treatment of varicose veins and venous insufficiency with different procedures were included and *** laser ablation(EVLA)and radiofrequency ablation(RFA)both are same safe and effective in terms of occlusion rate,and time to return to normal *** comparison with RFA or EVLT,Cure conservatrice et Hemodynamique de l’Insufficience Veineuse en Ambulatoire(CHIVA)may cause more bruising and make little or no difference to rates of limb infection,superficial vein thrombosis,nerve injury,or *** terms of recurrence of varicose veins,there is little or no difference between CHIVA and stripping,RFA,or *** saphenous vein recanalization is highest in the ultrasound-guided foam sclerotherapy(FS)group(51%)during 1 year of *** 2013 National Institute for Health and Care Excellence clinical guidelines recommend surgery as a third-line therapeutic option after EVLA or RFA and *** the mechanochemical endovenous ablation(MOCA)is a non-thermal,non-tumescent option and appears to be of similar efficacy to stab avulsion with no potential risk of nerve damage,the overall success rate of MOCA is lower than those of other procedures such as EVLA,RFA,or high ligation and *** is the most cost-effective therapeutic option,with RFA being a close second for the treatment of patients with varicose *** thermal ablation(EVLA or RFA)is recommended as a first-line treatment for varicose veins and has substituted the high ligation of saphenofemoral junctional reflux and stripping of varicose ***

关键词： Varicose veins Venous insufficiency High ligation and stripping Endovenous laser ablation Radiofrequency ablation Cure conservatrice et Hemodynamique de l’Insufficience Veineuse en Ambulatoire

Laparoscopic colonic anastomosis using a degradable stent in a porcine model

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World Journal of Gastroenterology 2016年第19期22卷 4707-4715页

作者： Liang Ma Xiu-Jun Cai hai-hong wang Yan-Lan Yu Di-Yu Huang Guang-Ju Ge hai-Yi Hu Shi-Cheng Yu Department of Gastroenterology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Department of General Surgery Sir Run Run Shaw Hospital and The Institute of Minimally Invasive Surgery Zhejiang University School of Medicine Department of Anesthesia Sir Run Run Shaw Hospital Zhejiang University School of Medicine

AIM: To explore the feasibility and safety of laparoscopic colonic anastomosis using a degradable stent in a porcine ***: Twenty Bama mini-pigs were randomly assigned to a stent group(n = 10) and control group(hand-sewn anastomosis, n = 10). The anastomotic completion and operation times were recorded, along with histological examination, postoperative general condition, complications, mortality, bursting pressure, and the average anastomotic circumference(AC).RESULTS: All pigs survived postoperatively except for one in the stent group that died from ileus at 11 wk postoperatively. The operation and anastomotic completion times of the stent group were significantly shorter than those of the control group(P = 0.004 and P = 0.001, respectively). There were no significant differences in bursting pressure between the groups(P = 0.751). No obvious difference was found between the AC and normal circumference in the stent group, but AC was significantly less than normal circumferencein the control group(P = 0.047, P < 0.05). No intestinal leakage and luminal stenosis occurred in the stent group. Histological examination revealed that the stent group presented with lower general inflammation and better ***: Laparoscopic colonic anastomosis with a degradable stent is a simple, rapid, and safe procedure in this porcine model.

关键词： Laparoscope Colon Anastomosis Stent Porcine model

Overexpression of dishevelled-1 attenuates wortmannin-induced hyperphosphorylation of cytoskeletal proteins in N2a cell

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Acta Pharmacologica Sinica 2005年第6期26卷 679-684页

作者： hai-hong wang, Ai-hong ZHANG, Ling-qiang ZHU, Qun wang, Jian-zhi wang~2 Department of Pathophysiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China DepartmentofPathophysiology TongjiMedicalCollegeHuazhongUniversityofScienceandTechnologyWuhan430030China

Aim: To investigate the effect of dishevelled-1 (DVL-1) on wortmannin-induced Alzheimer-like hyperphosphorylation of cytoskeletal proteins in mouse neuroblastoma 2a (N2a) cells. Methods: Cultured N2a cells were transitorily transfected with DVL-1 expression plasmid using Lipofectamine鈩?2000. Western blot and immunofluorescence microscopy were used to measure the phosphorylation of neurofilament and tau. Results: Level of phosphorylated neurofilament at SMI31 epitope and phosphorylated tau determined by PHF-1 was increased at 1 h and 3 h and back to normal at 6 h after wortmannin 1 |imol/L treatment. The highest level of phosphorylated neurofilament and phosphorylated tau was seen at 1 h and 3 h after wortmannin treatment, respectively. When DVL-1 protein was overexpressed, the hyperphosphorylation of neurofilament at SMI31 and SMI32 epitopes and tau atPHF-l(Ser-396/404),M4(Thr-231/Ser-235),andTau-l(Ser-198/199/202)epitopes was attenuated. Conclusion: Overexpression of mouse DVL-1 protein inhibits wortmannin-induced hyperphosphorylation of neurofilament and tau in N2a cells.

关键词： Alzheimer disease tau proteins neurofilament wortmannin dishevelled-1

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基于遗传算法的最优参差码搜索

系统工程与电子技术 2004年第6期26卷 711-713页

作者：陶海红王伶廖桂生西安电子科技大学雷达信号处理重点实验室陕西西安710071

提出了一种基于二进制编码遗传算法的参差时变滤波器设计,该方法采用遗传算法选择最优参差比使滤波器第一零点尽可能的浅,可在有效抑制杂波的同时避免目标丢失。遗传算法相对于传统最优参差码的选择,是一种全局随机搜索方法,收敛速度快... 详细信息

提出了一种基于二进制编码遗传算法的参差时变滤波器设计,该方法采用遗传算法选择最优参差比使滤波器第一零点尽可能的浅,可在有效抑制杂波的同时避免目标丢失。遗传算法相对于传统最优参差码的选择,是一种全局随机搜索方法,收敛速度快,有利于信息的实时处理。对于米波雷达所做的仿真结果和性能分析验证了该算法的可行性和有效性。

关键词：参差码遗传算法染色体第一零点

Efficacy evaluation for the treatment of unstable lumbar disc herniation by traditional and modified lamina osteotomy replantation

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Chinese Medical Journal 2013年第15期126卷 2840-2845页

作者： XU hong-hai wang Xiao-qing ZHANG Yue-lin GUO Xiong LIU Zong-zhi LUO Zhen-qun MA Qiang ZOU Qing- yang LIU Cong FANG hai-bo Xi An Jiao Tong Univ Coll Med Shaanxi Prov Pepoples Hosp Affiliated Hosp 3Dept Orthopaed Xian 710061 Shaanxi Peoples R China Xi An Jiao Tong Univ Coll Med Shaanxi Prov Pepoples Hosp Affiliated Hosp 3Dept Neurosurg Xian 710061 Shaanxi Peoples R China Xi An Jiao Tong Univ Coll Med Dept Fac Publ Hlth Xian 710061 Shaanxi Peoples R China

Background The traditional lamina osteotomy replantation method is prone to nerve root injury and low back pain recurrence. Our team has proposed a modified approach that improves the osteotomy site and its fixation procedure. The aim of this study was to evaluate the clinical efficacy of traditional and modified lamina replantation methods in treating unstable lumbar disc herniation. Methods From March 2008 to August 2011, 124 patients with unstable lumbar disc herniation were enrolled and randomly divided into the following two groups according to random digital table： group A （traditional group） consisting of 61 patients who underwent traditional laminectomy replantation, and group B （modified group） consisting of 63 patients who underwent modified lamina replantation. Both surgeries were performed by the same surgeons. The two groups had no significant difference in gender, age, symptoms, time of onset and the prominent segment. Visual analogue scale （VAS）, Oswertry disability index （ODI）, and Japanese Orthopaedic Association （JOA） scores, operative time, blood loss, complication rate, radiographic healing rates, and low back pain recurrence rates were compared between the two groups. Results There were 121 patients followed up for more than one year, and the follow-up rate was 97.6%. Nerve injury occurred in two patients （3.3%） in the modified group and 12 patients （20.0%） in the traditional group. Dural injury occurred in one patient （1.6%） in the modified group and seven patients （11.7%） in the traditional group. Pseudarthrosis occurred in two patients in the modified group and in 18 patients in the traditional group with 1-year fusion rates of 96.7% and 70.0%, respectively. Recurrence of lower back pain after one year was noted in three patients （4.9%） in the modified group, and in 15 （25.0%） in the traditional group. Leg pain recurrence was noted in one patient （1.6%） in the modified group and in three cases （5.0%） in the traditional group. The one-year hea

关键词： lumbar disc herniation lamina replantation spine clinical outcome

Oxytocin decreases colonic motility of cold water stressed rats via oxytocin receptors

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World Journal of Gastroenterology 2014年第31期20卷 10886-10894页

作者： Xiao Yang Tao-Fang Xi Yu-Xian Li hai-hong wang Ying Qin Jie-Ping Zhang Wen-Ting Cai Meng-Ting Huang Ji-Qiao Shen Xi-Min Fan Xuan-Zheng Shi Dong-Ping Xie Department of Physiology Shanghai Tenth People’s Hospital Tongji University School of Medicine Division of Gastroenterology Department of Internal Medicine University of Texas Medical Branch 301 University Boulevard

AIM: To investigate whether cold water intake into the stomach affects colonic motility and the involvement of the oxytocin-oxytocin receptor pathway in rats. METHODS: Female Sprague Dawley rats were used and some of them were ovariectomized. The rats were subjected to gastric instillation with cold (0-4 degrees C, cold group) or room temperature (20-25 degrees C, control group) saline for 14 consecutive days. Colon transit was determined with a bead inserted into the colon. Colonic longitudinal muscle strips were prepared to investigate the response to oxytocin in vitro. Plasma concentration of oxytocin was detected by ELISA. Oxytocin receptor expression was investigated by Western blot analysis. Immunohistochemistry was used to locate oxytocin receptors. RESULTS: Colon transit was slower in the cold group than in the control group (P < 0.05). Colonic smooth muscle contractile response to oxytocin decreased, and the inhibitory effect of oxytocin on muscle contractility was enhanced by cold water intake (0.69 +/- 0.08 vs 0.88 +/- 0.16, P < 0.05). Atosiban and tetrodotoxin inhibited the effect of oxytocin on colonic motility. Oxytocin receptors were located in the myenteric plexus, and their expression was up-regulated in the cold group (P < 0.05). Cold water intake increased blood concentration of oxytocin, but this effect was attenuated in ovariectomized rats (286.99 +/- 83.72 pg/mL vs 100.56 +/- 92.71 pg/mL, P < 0.05). However, in ovariectomized rats, estradiol treatment increased blood oxytocin, and the response of colonic muscle strips to oxytocin was attenuated. CONCLUSION: Cold water intake inhibits colonic motility partially through oxytocin-oxytocin receptor signaling in the myenteric nervous system pathway, which is estrogen dependent. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.

关键词： Intragastric cold water stress Colonic motility Estradiol Oxytocin Oxytocin receptor Irritable bowel syndrome