Laparoscopic colonic anastomosis using a degradable stent in a porcine model
Laparoscopic colonic anastomosis using a degradable stent in a porcine model作者机构：Department of Gastroenterology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Department of General Surgery Sir Run Run Shaw Hospital and The Institute of Minimally Invasive Surgery Zhejiang University School of Medicine Department of Anesthesia Sir Run Run Shaw Hospital Zhejiang University School of Medicine
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2016年第22卷第19期
页 面：4707-4715页
核心收录：
主 题：Laparoscope Colon Anastomosis Stent Porcine model
摘 要：AIM: To explore the feasibility and safety of laparoscopic colonic anastomosis using a degradable stent in a porcine model.METHODS: Twenty Bama mini-pigs were randomly assigned to a stent group(n = 10) and control group(hand-sewn anastomosis, n = 10). The anastomotic completion and operation times were recorded, along with histological examination, postoperative general condition, complications, mortality, bursting pressure, and the average anastomotic circumference(AC).RESULTS: All pigs survived postoperatively except for one in the stent group that died from ileus at 11 wk postoperatively. The operation and anastomotic completion times of the stent group were significantly shorter than those of the control group(P = 0.004 and P = 0.001, respectively). There were no significant differences in bursting pressure between the groups(P = 0.751). No obvious difference was found between the AC and normal circumference in the stent group, but AC was significantly less than normal circumferencein the control group(P = 0.047, P 0.05). No intestinal leakage and luminal stenosis occurred in the stent group. Histological examination revealed that the stent group presented with lower general inflammation and better healing.CONCLUSION: Laparoscopic colonic anastomosis with a degradable stent is a simple, rapid, and safe procedure in this porcine model.
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