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Security-Enhanced Directional Modulation Based on Two-Dimensional M-WFRFT

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China Communications 2024年第5期21卷 229-248页

作者： zhou zhuang Luo Junshan Wang Shilian Xia Guojiang School of Electronic Science National University of Defense TechnologyChangsha 410073China Beijing Institute of Astronautical Systems Engineering Beijing 100076China

Directional modulation(DM)is one of the most promising secure communication ***,when the eavesdropper is co-located with the legitimate receiver,the conventional DM has the disadvantages of weak anti-scanning capability,anti-deciphering capability,and low secrecy *** response to these problems,we propose a twodimensional multi-term weighted fractional Fourier transform aided DM scheme,in which the legitimate receiver and the transmitter use different transform terms and transform orders to encrypt and decrypt the confidential *** order to further lower the probability of being deciphered by an eavesdropper,we use the subblock partition method to convert the one-dimensional modulated signal vector into a twodimensional signal matrix,increasing the confusion of the useful *** results demonstrate that the proposed DM scheme not only provides stronger anti-deciphering and anti-scanning capabilities but also improves the secrecy rate performance of the system.

关键词： bit error rate directional modulation phased array secrecy rate weighted fractional Fourier transform

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Enhancement of liquid-liquid micromixing performance in curved capillary microreactor by generation of Dean vortices

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Chinese Journal of Chemical Engineering 2024年第4期68卷 76-82页

作者： Shaoyun Wu zhuang Ma Zichi Yang Suying Zhao Caijin zhou Huidong Zheng Fujian Engineering Research Center of Advanced Manufacturing Technology for Fine Chemicals College of Chemical EngineeringFuzhou UniversityFuzhou 350108China Qingyuan Innovation Laboratory Quanzhou362114China

Micromixing efficiency is an important parameter for evaluating the multiphase mass transfer performance and reaction efficiency of *** this work,the novel curved capillary reactor with different shapes was designed to generate Dean flow,which was used to enhance the liquid-liquid micromixing *** Villermaux-Dushman probe reaction was employed to characterize the micromixing performance in different curved capillary *** effects of experiment parameters such as liquid flow rate,inner diameter,tube length,and curve diameter on micromixing performance were systematically *** the optimal conditions,the minimum value of the segmentation factor XS was *** was worth noting that at the low Reynolds number(Re<30),the change of curved shape on the capillary microreactor can significantly improve the micromixing performance with XS reduced by 37.5%.Further,the correlations of segment index XS with dimensionless factor such as Reynolds number or Dean number were developed,which can be used to predict the liquid-liquid micromixing performance in capillary microreactors.

关键词： Microreactor Process intensification Micromixing performance Dean flow

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Transient stimulated Raman scattering spectroscopy and imaging

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Light(Science & Applications) 2024年第4期13卷 654-663页

作者： Qiaozhi Yu Zhengjian Yao Jiaqi zhou Wenhao Yu Chenjie zhuang Yafeng Qi Hanqing Xiong National Biomedical Imaging Center College of Future TechnologyPeking UniversityBeijing 100871China Biomedical Engineering Department College of Future TechnologyPeking UniversityBeijing 100871China

Stimulated Raman scattering(SRS)has been developed as an essential quantitative contrast for chemical imaging in recent ***,while spectral lines near the natural linewidth limit can be routinely achieved by state-of-the-art spontaneous Raman microscopes,spectral broadening is inevitable for current mainstream SRS imaging *** is because those SRS signals are all measured in the frequency *** is a compromise between sensitivity and spectral resolution:as the nonlinear process benefits from pulsed excitations,the fundamental time-energy uncertainty limits the spectral ***,the spectral range and acquisition speed are mutually *** we report transient stimulated Raman scattering(T-SRS),an alternative time-domain strategy that bypasses all these fundamental conjugations.T-SRS is achieved by quantum coherence manipulation:we encode the vibrational oscillations in the stimulated Raman loss(SRL)signal by femtosecond pulse-pair sequence excited vibrational wave packet *** Raman spectrum was then achieved by Fourier transform of the time-domain SRL *** all Raman modes are impulsively and simultaneously excited,T-SRS features the natural-linewidth-limit spectral line shapes,laser-bandwidth-determined spectral range,and improved ***~150-fs laser pulses,we boost the sensitivity of typical Raman modes to the sub-mM *** all-plane-mirror high-speed time-delay scanning,we further demonstrated hyperspectral SRS imaging of live-cell metabolism and high-density multiplexed imaging with the natural-linewidth-limit spectral resolution.T-SRS shall find valuable applications for advanced Raman imaging.

关键词： scattering excited mutually

Japanese encephalitis following liver transplantation: A rare case report

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World Journal of Clinical Cases 2020年第2期8卷 337-342页

作者： Zhi-Li Qi Li-Ying Sun Jing Bai hai-zhou zhuang Mei-Li Duan Department of Intensive Care Unit Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China Beijing Key Laboratory of Tolerance Induction and Organ Protection in Transplantation Beijing Friendship HospitalCapital Medical UniversityBeijing 100050China

BACKGROUND Japanese encephalitis(JE) is a serious public health concern with a high mortality rate in many Asian countries. For many years, JE virus(JEV) was considered the major cause of viral encephalitis in Asia. Although most JE cases are asymptomatic, the case fatality rate approaches 30%, and approximately 30%–50% of survivors have long-term neurological sequelae. To the best of our knowledge, JEV infection has never been reported following liver *** SUMMARY We report a case of a woman who underwent liver transplantation for autoimmune liver disease but presented with fever and neurological symptoms 13 d after transplantation. Magnetic resonance imaging revealed JEV infection,and positive immunoglobulin M antibody to JEV in blood and cerebrospinal fluid confirmed JE. The patient was treated with antiviral agents, immune regulation,and organ function support. No neurological sequelae were present after 1 year of *** Imaging and lumbar puncture examination should be performed as soon as possible in patients with fever and central nervous system symptoms after liver transplantation, and the possibility of atypical infection should be considered,which is helpful for early diagnosis and improved prognosis.

关键词： Liver transplantation Japanese encephalitis virus Neurological complications Infection Case report

A novel stiffness optimization model of space telescopic boom based on locking mechanism

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Frontiers of Mechanical Engineering 2024年第3期19卷 41-59页

作者： Kun XU Xinghan zhuang zhou SU Qiuhong LIN Shouzhi REN Hang XIAO Xilun DING School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China Beijing Institute of Spacecraft System Engineering Beijing 100094China

The deployable telescopic boom,whose mass and stiffness play crucial roles,is extensively used in the design of space-deployable ***,the most existing optimal design that neglects the influence of the locking mechanisms in boom joints cannot raise the whole stiffness while reducing the boom *** tackle this challenge,a novel optimization model,which utilizes the arrangement of the locking mechanisms to achieve synchronous improvement of the stiffness and mass,is *** proposed optimization model incorporates a novel joint stiffness model developed based on an equivalent parallel mechanism that enables the consideration of multiple internal stiffness factors of the locking mechanisms and tubes,resulting in more accurate representations of the joint stiffness *** analysis shows that the proposed stiffness model achieves more than at least 11% improved accuracy compared with existing ***,case verification shows that the proposed optimization model can improve stiffness while effectively reducing mass,and it is applied in boom optimization design.

关键词： deployable telescopic boom locking mechanism stiffness model clearance error optimization model

Synergistic effects of three traditional herbs green tea,mulberry leaf and corn silk on glucose uptake level of L6 myoblasts and the hypoglycemic mechanism

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Traditional Medicine Research 2024年第7期9卷 1-12页

作者： Jing-Na zhou Ming-Yue Li Ting-Ting Zhang Jing-Yang Lu Min Zhang Peng-Wei zhuang hai-Xia Chen Tianjin Key Laboratory for Modern Drug Delivery&High-Efficiency School of Pharmaceutical Science and TechnologyTianjin UniversityTianjin 300072China. School of Food Science and Bioengineering Tianjin Agricultural UniversityTianjin 300384China. State Key Laboratory of Nutrition and Safety Tianjin University of Science&TechnologyTianjin 300457China. haihe Laboratory of Modern Chinese Medicine Chinese Materia Medica CollegeTianjin University of Traditional Chinese MedicineTianjin 301617China.

Background:Green tea,mulberry leaf and corn silk are traditional herbs used in the prevention and treatment of diabetes in China for a long time,but their synergistic hypoglycemic effects and mechanisms remain ***:The effective components of green tea,mulberry leaf and corn silk were extracted and *** design of experiments was used to study the influences of different combinations on the cell viability and glucose uptake level of L6 myoblasts,so as to determine the optimal synergistic hypoglycemic *** possible hypoglycemic mechanism of the optimal synergistic combination was explored by cytotoxicity assay,glucose uptake assay,and western ***:Three polyphenol enrichment fractions of the herbs,30%ethanol elution fraction of green tea(GT),50%ethanol elution fraction of mulberry leaf(ML)and 60%ethanol elution fraction of corn silk(CS)were *** antioxidant activities of GT-30%,ML-50%and CS-60%were superior to those of crude extracts,and showed strong potential inα-amylase andα-glucosidase inhibition *** optimal synergistic combination of crude extracts G7(crude extract of green tea:crude extract of mulberry leaf:crude extract of corn silk=1:5:3),polyphenol enrichment fractions R3(GT-30%:ML-50%:CS-60%=1:7:1)and monomers X2(epigallocatechin gallate:morusin:formononetin=3:1:2)were selected,respectively.G7,R3,and X2 showed promoting effects on the cell viability and glucose uptake of L6 myoblasts within the detected concentration *** addition,G7,R3,and X2 could increase the expression levels of p-PI3K/PI3K and p-Akt/Akt in L6 myoblasts,and promote the translocation of Glut4,but G7 and R3 showed more significant ***:The synergistic hypoglycemic effects of green tea,mulberry leaf and corn silk had the characteristics of multiple-components and multiple-targets with p-PI3K/PI3K,p-Akt/Akt and the translocation of Glut4 signal pathways *** three traditional herbs might have the potential

关键词： green tea mulberry leaf corn silk synergistic effect type 2 diabetes mellitus mechanism

Oleanolic acid inhibits colon cancer cell stemness and reverses chemoresistance by suppressing JAK2/STAT3 signaling pathway

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BIOCELL 2024年第7期48卷 1037-1046页

作者： RUOYU CHEN YIMAN WU FENG WANG JUNTAO zhou HUAZHANG zhuang WEI LI Department of Anus and Intestine Surgery Shenzhen Longhua District Central HospitalShenzhenChina Department of Urology Shenzhen Longhua District Central HospitalShenzhenChina

Background:Oleanolic acid(OA),a pentacyclic triterpenoid exhibiting speciﬁc anti-cancer properties and highly effective antioxidant activity,was isolated from traditional Chinese medicinal ***,the OA that impacts colon cancer(CC)cells and its underlying mechanisms remain poorly ***:The cytotoxic effect of OA alone or OA-5-Fluorouracil(5-FU)combination on normal and CC cells was analyzed by methyl thiazolyl diphenyl-tetrazolium bromide(MTT).Then,the impact of OA on CC cell lines(LoVo and HT-29)proliferation and stemness were measured using colon formation and tumorsphere formation ***-binding transcription factor 4(Oct4),Prominin-1(CD133),Nanog,and transcription factor SOX-2(SOX2)are cell stemness-related indicators whose expression was assessed usingﬂuorescence qPCR assay,Western blotting,and *** effect of OA on the proliferative potency of CC cells was evaluated using an in vivo ***:The stem-like characteristics and clone production of colon cancer cells were markedly reduced by OA alone or in combination with ***,OA increases the susceptibility of CC cells to 5-FU by blocking the cell stemness-related markers(CD133,Nanog,SOX2,and Oct4)expression levels both in vitro and in vivo,as well as by inactivating the activator of transcription 3(STAT3 signaling)and Janus kinase 2/signal transducer(JAK2).Conclusion:Theseﬁndings imply that oleanolic acid,both in vitro and in vivo,suppresses the JAK2/STAT3 pathway,which in turn reverses chemoresistance and decreases colon cancer cell ***,by reducing the recommended amount of 5-FU,this strategy may improve chemotherapeutic effectiveness and minimize undesired side effects.

关键词： Colon cancer,Oleanolic acid,Stemness,5-FU JAK2/STAT3 signaling pathway

Existence of multi-hump generalized homoclinic solutions for a class of reversible systems

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Science China Mathematics 2024年

作者： Shengfu Deng Yan zhou Jinsen zhuang School of Mathematical Sciences Huaqiao University

In this paper, we investigate a class of reversible dynamical systems in four dimensions. The spectrums of their linear operators at the equilibria are assumed to have a pair of positive and negative real eigenvalues and a pair of purely imaginary eigenvalues for the small parameterμ> 0, where these two real eigenvalues bifurcate from a double eigenvalue 0 forμ=0. It has been shown that this class of systems owns a generalized homoclinic solution with one hump at the center （a homoclinic solution exponentially approaching a periodic solution with a small amplitude）. This paper gives a rigorous existence proof of two-hump *** two humps are far away and are glued by the small oscillations in the middle if some appropriate free constants are activated. The obtained results are also applied to some classical systems. The ideas here may be used to study the existence of 2k-hump solutions.

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An Integrated Control Framework for Torque Vectoring and Active Suspension System

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 62-73页

作者： Jiwei Feng Jinhao Liang Yanbo Lu Weichao zhuang Dawei Pi Guodong Yin Liwei Xu Pai Peng Chaobin zhou School of Mechanical Engineering Southeast UniversityNanjing 211189China School of Mechanical Engineering Nanjing University of Science and TechnologyNanjing 210094China School of Mechano-Electronic Engineering Lanzhou University of TechnologyLanzhou 730050China

Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle *** paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control *** the nonlinear characteristic of the tire model leads to a relatively heavier computational *** facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)*** a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort *** in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy ***,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)*** results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability.

关键词： Four-wheel independently driven electric vehicles Tire nonlinearity Linear-time-varying(LTV)model Model predictive control Rapid control prototype