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Interactive modeling of lofted shapes from a single image

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Computational Visual Media 2020年第3期6卷 279-289页

作者： Congyue Deng Jiahui huang Yong-Liang Yang Tsinghua University Beijing100084China University of Bath BathBA27AYUK

Modeling the complete geometry of general shapes from a single image is an ill-posed *** hints are often incorporated to resolve ambiguities and provide guidance during the modeling process. In this work, we present a novel interactive approach for extracting high-quality freeform shapes from a single image. This is inspired by the popular lofting technique in many CAD systems, and only requires minimal user input. Given an input image, the user only needs to sketch several projected cross sections, provide a"main axis", and specify some geometric relations. Our algorithm then automatically optimizes the common normal to the sections with respect to these constraints,and interpolates between the sections, resulting in a high-quality 3 D model that conforms to both the original image and the user input. The entire modeling session is efficient and intuitive. We demonstrate the effectiveness of our approach based on qualitative tests on a variety of images, and quantitative comparisons with the ground truth using synthetic images.

关键词： image User sketch

Effects of basic fibroblast growth factor on superoxide dismutase activity and malondialdehyde content in the rat brain following intracerebral hemorrhage

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Neural Regeneration Research 2008年第9期3卷 971-974页

作者： Hongqiao Wei Juen huang Junjie huang Bing Li Qianming Li Department of Physiology Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China Department of Histology and Embryology Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China Department of Physiology Youjiang Medical College for Nationafities Baise 533000 Guangxi Zhuang Autonomous Region China Department of Physiology Xinxiang Medical College Xinxiang 453000 He＇nan Province China

BACKGROUND： Studies have confirmed that basic fibroblast growth factor （bFGF） promotes neuronal survival and neurite outgrowth. OBJECTIVE： To compare and verify the effects of bFGF on superoxide dismutase activity and malondialdehyde content in rat brain tissues surrounding a hemorrhagic lesion, as well as the hippocampus at the hemorrhagic side. DESIGN, TIME AND SETTING： The randomized, controlled, neurobiological study was performed at the Science Experimental Center and Research Laboratory, Guangxi Medical University, China, from September to December 2006. MATERIALS： Ninety-two adult, healthy, Wistar rats of equal gender were used to establish intracerebral hemorrhage by infusing type VII collagenase into the left internal capsule. Type Ⅶ collagenase （Sigma, USA）, superoxide dismutase and malondialdehyde kits （Jiancheng, China）, and bFGF （Institute of Bioengineering, Ji＇nan University, China） were used for this study. METHODS： Ninety successfully lesioned rats were equally and randomly divided into three groups. Rats in the bFGF group were intramuscularly injected daily with bFGF （8 ug/kg）. Rats in the saline control group received an equal volume of saline. The rats in the model group did not receive other interventions. Superoxide dismutase activity was measured using the xanthine oxidase method. Malondialdehyde contents were detected using the thiobarbituric acid method. MAIN OUTCOME MEASURES： At 1, 3, and 7 days following intracerebral hemorrhage, superoxide dismutase and malondialdehyde were determined in the brain tissue surrounding the hematoma and in the hippocampus in the affected hemisphere. RESULTS： In brain tissue surrounding the hematoma, superoxide dismutase activity was significantly increased in the bFGF group at 3 and 7 days after intracerebral hemorrhage compared with the saline control group, whereas malondialdehyde content was significantly decreased （P 〈 0.05）. In the hippocampus, superoxide dismutase activity was significantly increased in

关键词： basic fibroblast growth factor intracerebral hemorrhage superoxide dismutase malondialdehyde

Special issue on recent progress in organic electronics and photonics

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Science China Chemistry 2017年第4期60卷 431-432页

作者： Fei huang Yong Cao Institute of Polymer Optoelectronic Materials and Devices State Key Laboratory of Luminescent Materials and Devices South China University of Technology Guangzhou 510641 China

Organic electronic and photonic devices have received tre- mendous attention from both academia and industry be- cause of their great promise for practical use as organic light-emitting diodes （OLEDs）, organic solar cells （OSCs）, organic field-effect transistors （OFETs）, and chemical and biological sensors. During the past decade, remarkable pro- gress has been achieved in this cutting-edge research field, which has opened numerous opportunities for the fabrica- tion of advanced organic electronic devices. For instance, solution-processable OSCs with a power conversion effi- ciency （PCE） exceeding 12% have been achieved, which meets the basic requirements for commercialization. Re- cently, active-matrix OLEDs that can be used in smart phones, televisions, and as flexible displays for portable devices have been commercialized.

关键词：电子学有机发光二极管光子学有机太阳能电池场效应晶体管有机电子器件功率转换效率生物传感器

Probing the internal structure of baryons

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National Science Review 2021年第11期8卷 54-61页

作者： Guangshun huang Rinaldo Baldini Ferroli BESⅢ Collaboration Department of Modern Physics University of Science and Technology of China State Key Laboratory of Particle Detection and Electronics INFN Laboratori Nazionali di Frascati Institute of High Energy Physics Chinese Academy of Sciences

Electromagnetic form factors are fundamental observables that describe the electric and magnetic structure of hadrons and provide keys to understand the strong interaction. At the Beijing Spectrometer(BESⅢ),form factors have been measured for different baryons in the time-like region for the first time or with the best precision. The results are presented with examples focused on but not limited to the proton/neutron,the, with a strange quark, and the c, with a charm quark.

关键词： baryon structure form factor threshold effect abnormal production

Genetic polymorphisms of the renin-angiotensin-aldosterone system in Chinese patients with end-stage renal disease secondary to IgA nephropathy

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Chinese Medical Journal 2010年第22期123卷 3238-3242页

作者： huang hai-dong LIN Fu-jun LI Xin-juan WANG Li-rui JIANG Geng-ru Department of Nephrology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200092 China

Background Genetic variability in the renin-angiotensin-aldosterone system may modify renal responses to injury and disease progression. The angiotensin I-converting enzyme （ACE） gene insertion/deletion （I/D）, the angiotensinogen （AGT） gene, M235T, the aldosterone synthase （CYP11B2） gene, C-344T, and the angiotensin II type 1 receptor （AT1R） gene, Al166C, have been shown to be associated with IgA nephropathy （IgAN） and its progression. We determined the presence of these polymorphisms in 130 Chinese patients with IgAN, including 47 patients with end-stage renal disease （ESRD） and 120 healthy Chinese subjects, to assess their impact on the susceptibility to disease and the liability of progression to ESRD. Methods Genotyping was performed with DNA isolated from peripheral leucocytes using polymerase chain reaction amplification of the polymorphic sequence, restriction enzyme digestion, and separation and identification of DNA fragments. Clinical data from renal biopsies were collected. Results ACE, AGT, CYP and AT1R genotype distributions were similar in patients with IgAN and in controls. Comparing patients with ESRD （IgAN-ESRD） and those without ESRD （IgAN-non ESRD）, there was a significant increase only in the ACE DD genotype （P 〈0.05） among the four gene polymorphisms. There was significant dominance of the male （P 〈0.05）, more marked hypertension （P 〈0.01）, proteinuria （P 〈0.01） and increased serum creatinine during renal biopsy （P〈0.01） in the IgAN-ESRD group. Conclusion Among the ACE, AGT, ATIR and CYP gene polymorphisms, only the DD genotype may predispose the individual to increased risk of progression to ESRD in the Chinese population.

关键词： IgA nephropathy end-stage renal disease genetic polymorphism renin-angiotensin-aldosterone system

GC-MS Analysis and Antibacterial Activity Study of Volatile Oil from 11 Kinds of Aurantii Fructus Immaturus Processed Products

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Medicinal Plant 2020年第4期11卷 38-43页

作者： Liuping WANG Juanling huang Baoping tao Yaohua LI Zhenzhen PAN Guangxi University of Chinese Medicine Nanning 530200 China Undergraduates from College of Pharmacy Guangxi University of Chinese Medicine Nanning 530200 China

[Objectives]To study the volatile components and antibacterial effects of 11 kinds of Aurantii Fructus Immaturus processed products.[Methods]11 kinds of Aurantii Fructus Immaturus processed products were obtained according to the traditional processing method,the volatile oil was extracted by steam distillation,and the composition of volatile oil in the 11 kinds of processed products was analyzed by gas chromatography-mass spectrometry(GC-MS).the relative percentage content of each component in these 11 kinds of processed products was determined using the peak area *** drug sensitivity activity of the volatile oil of these 11 kinds of processed products was tested using the K-B paper diffusion method and the minimum inhibition volume fraction of volatile oil of these 11 kinds of processed products was tested using the microdilution method.[Results]The highest yield of volatile oil of 11 kinds of these processed products was baking(5.193%),and the lowest was stir-bake to scorch(1.998%).A total of 36 chemical components were identified from the volatile oils of these 11 kinds of processed *** components with the most volatile oil were stir-bake to scorch(24 kinds),and the components with the least volatile oil were the method of processing with rice-washed water(15 kinds).They contain 8 kinds of common chemical components,such as limonene,linalool,myrcene,α-*** highest content of limonene came from processing with honey(60.93%),the lowest came from processing with rice-washed water(55.25%);the highest content of linalool came from processing with rice-washed water(7.139%),the lowest came from processing with honey(5.436%);the highest content of myrcene came from processing with honey(1.899%),the lowest came from stir-bake to scorch(1.632%);the highest content ofα-pinene came from raw Aurantii Fructus Immaturus(2.355%),and the lowest came from stir-bake to scorch(1.618%).The volatile oil of these 11 kinds of Aurantii Fructus Immaturus proc

关键词： Aurantii Fructus Immaturus Processed products Volatile oil Gas chromatography-mass spectrometry(GC-MS) Antibacterial activity

Influence of CYP2C9*3 and CYP4F2 rs2108622 gene polymorphisms on over-anticoagulation and bleeding complications of warfarin therapy in Chinese patients:a cohort study

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Journal of Chinese Pharmaceutical Sciences 2021年第6期30卷 484-494页

作者： Yushan Wu Limei Yang Xuhui huang Feng huang tao Han Cardiac surgery Provincial Clinical College of Fujian Medical University/Fujian Provincial HospitalFuzhou 350001China Pharmacy Department Provincial Clinical College of Fujian Medical University/Fujian Provincial HospitalFuzhou350001China

In this retrospective cohort study,we aimed to identify the influence of the CYP2C9*3 and CYP4F2 rs2108622 gene alleles on over-anticoagulation and bleeding complications associated with warfarin therapy.A total of 196 patients were included,including 80 males,the mean age was 50.8±10.7 years,and the average follow-up was 26.9±11.8 *** patients underwent heart valve replacement surgery in the Cardiovascular Surgery of Fujian Provincial Hospital between January 2018 and August 2019,who took warfarin for at least 3 months and had target international normalized ratio(INR)between 1.8 and *** of CYP2C9*3 and CYP4F2 rs2108622 genes were tested by polymerase chain reaction(PCR)-gene sequencing ***19.0 software was utilized to analyze the association between genotypes and warfarin-related over-anticoagulation and bleeding *** the 434 patient-years,18 severe bleedings and 59 mild ones occurred in 31 *** with CYP2C9*1/*3 were associated with a higher over-anticoagulation risk compared with the*1/*1 carriers(hazard rate(HR)7.10;95%confidence interval(CI):2.54–19.79,P<0.001).The CYP4F2 rs2108622 mutant genotype did not cause significant increase in bleeding risk(HR 0.89;95%CI:0.43–1.82,P=0.74)or over-anticoagulation(HR 0.43;95%CI:0.16–1.13,P=0.09).Meanwhile,Kaplan-Meier survival curves showed that the time to over-anticoagulation in CYP2C9*1/*3 carriers was significantly shorter compared with the*1/*1 carriers(log-rank test,P<0.001),while that in CYP4F2 rs2108622 mutant genotype patients was longer compared with the wild-type patients(P=0.05).CYP2C9*3 and CYP4F2 rs2108622 might be major predictive factors of over-anticoagulation for warfarin therapy in Chinese patients.

关键词： Anticoagulation Genetics Bleeding disorders&coagulopathies Risk management

Novel cover selection criterion for spatial steganography using linear pixel prediction error

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Science China(Information Sciences) 2016年第5期59卷 245-247页

作者： Wei huang Xianfeng ZHAO Software School Xiamen University State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of Sciences

Dear editor,In recent years,steganography and steganalysis[1]of empirical covers have been developing *** cover,such as image and other multimedia,is one of the most commonly used content in daily life,however,the model of images is still ***,the combat against image steganography and steganalysis would be challenging yet beneficial.

关键词： Novel cover selection criterion for spatial steganography using linear pixel prediction error Figure

Total Synthesis of dl-Ligustiphenol

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Chinese Chemical Letters 1996年第10期7卷 896-897页

作者： huang, YH Yu, DQ CHINESE ACAD MED SCI INST MAT MEDBEIJING 100050PEOPLES R CHINA BEIJING UNION MED COLL BEIJING 100050PEOPLES R CHINA

----(-)S-Ligustiphenol is a new sesquiterpene compound with antiinflammatory and immunosuppressive activities. The total synthesis of its racemate was carried out by a six-step reaction sequence including bromination of aldehyde, iodination of m-cresol, protection of phenolic hydroxyl, Grignard reaction,aldol condensation, etc. The target compound was characterized by comparing its H-1 NMR,MS and IR spectra with natural (-) ligustiphenol.

关键词： Total Synthesis of dl-Ligustiphenol