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Modification of Corrosion Resistance of the Plain Carbon Steels by Pulsed Electric Current

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Acta Metallurgica Sinica(English Letters) 2018年第12期31卷 1233-1239页

作者： Jun-Yang Gao Xue-Bing Liu hai-fei zhou Xin-Fang Zhang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Zhejiang Electric Power Corporation Research Institute Hangzhou 310014China

The fracture of pipelines caused by corrosion cracks and the resulting oil and gas leakage can lead to great environmentalpollution and economic losses. These negative effects are due to serious corrosion of the plain carbon steels used for armorof flexible pipe in oil and gas transmission medium. However, corrosion resistance of carbon steel armors has yet to beimproved. In this study, the relationship between corrosion resistance and pearlite fraction in the plain carbon steels hasbeen investigated through the application of pulsed electric current. Based on immersion test and electrochemical mea-surement, pulsed electric current increases the corrosion resistance of the plain carbon steels by reducing the fraction ofpearlite phase. Pitting corrosion, which tends to initiate by galvanic corrosion of ferrite and cementite, is therefore inhibiteddue to the decrease in pearlite fraction （mixture of ferrite and cementite） under electropulsing.

关键词： Corrosion resistance Pearlite Pulsed electric current Plain carbon steel

Manipulating Precipitation Through Thermomechanical Treatment to Control Corrosion Behavior of an Al–Cu–Mg Alloy

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Acta Metallurgica Sinica(English Letters) 2022年第9期35卷 1547-1558页

作者： Xiu-Rong Zhu Jun Wang Wei-Ning Shi Xue-Bing Liu Xin-Fang Zhang hai-fei zhou Ningbo Branch Ordnance Science Institute of ChinaNingbo315103China School of Metallurgical and Ecological Engineering Metallurgical University of Science and Technology of BeijingBeijing100083China Zhejiang Electric Power Corporation Research Institute Hangzhou310000China

Controlling the precipitation through thermomechanical treatment is an important method to improve the corrosion resistance of Al–Cu–Mg alloys. In this study, the corrosion behaviors of Al–Cu–Mg alloys in the solution-treated state and retrogressiontreated state under cold rolling deformation and then natural aging were investigated. In the solution-treated series alloys, the cold-rolled deformation improved the resistance to intergranular corrosion by suppressing the precipitation of the S-phase on the grain boundaries. The increased pitting potential and corrosion potential were related to the increased concentration of solute atoms within the grain interiors and the eliminated S-phase on grain boundaries. In the retrogression-treated series alloys, the 30% cold rolling deformation stimulated the growth of the S-phase and transformed the S-phase distribution from discontinuous to continuous on the grain boundaries, thereby changing the pitting corrosion to the network corrosion morphology. The precipitation of the S-phase with large dimension within the grain interiors contributed to the decreased pitting potential and corrosion potential.

关键词： Thermomechanical treatment Precipitation Intergranular corrosion Pitting corrosion

Transarterial chemoembolization combined with lenvatinib and sintilimab vs lenvatinib alone in intermediate-advanced hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 52-61页

作者： fei-Da Wu hai-Feng zhou Wei Yang Di Zhu Bi-fei Wu hai-Bin Shi Sheng Liu Wei-Zhong zhou Department of Interventional Radiology The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is the most common form of liver cancer that has limited treatment options and a poor *** chemoembolization(TACE)is the first-line treatment for intermediate-stage HCC but can induce tumour hypoxia,thereby promoting *** studies suggested that combining TACE with anti-angiogenic therapies and immunotherapy might im-prove ***,a tyrosine kinase inhibitor,has demonstrated superior outcomes compared to sorafenib,while immune checkpoint inhibitors such as sintilimab show potential when combined with ***,the efficacy and safety of TACE combined with lenvatinib and sintilimab(TACE+SL)compared to TACE with lenvatinib alone(TACE+L)in patients with intermediate-ad-vanced HCC has not yet been *** To evaluate the efficacy and safety of TACE+SL therapy in comparison to TACE+L therapy in patients with intermediate-advanced *** A retrospective analysis was performed on patients with intermediate-advanced HCC who received TACE plus lenvatinib with or without sintilimab between September 2019 and September *** characteristics were compared,and propensity score matching was *** survival(OS),progression-free survival(PFS),and objective response rate(ORR)were evaluated between the two groups,and adverse events were *** The study included 57 patients,with 30 in the TACE+SL group and 27 in the TACE+L *** TACE+SL group demonstrated significantly improved median PFS and OS compared to the TACE+L group(PFS:14.1 months vs 9.6 months,P=0.016;OS:22.4 months vs 14.1 months,P=0.039),along with a higher ORR(70.0%vs 55.6%).After propensity score matching,30 patients were included,with the TACE+SL group again showing longer median PFS and a trend toward improved OS(PFS:14.6 months vs 9.2 months,P=0.012;OS:23.9 months vs 16.3 months,P=0.063),and a higher ORR(73.3%vs 53.3%).No severe adverse events were *** TACE+SL demonstrat

关键词： Hepatocellular carcinoma Transarterial chemoembolization Sintilimab Lenvatinib Immunotherapy Programmed cell death 1 Prognosis

Detection of Gamma-Rays from the Protostellar Jet in the HH 80–81 System

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Research in Astronomy and Astrophysics 2022年第2期22卷 183-188页

作者： Da-hai Yan Jia-Neng zhou Peng-fei Zhang Key Laboratory for the Structure and Evolution of Celestial Objects Yunnan ObservatoriesChinese Academy of SciencesKunming 650011China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Department of Astronomy Key Laboratory of Astroparticle Physics of Yunnan ProvinceYunnan UniversityKunming 650091China

Considering that the existence of relativistic particles in the protostellar jet has been confirmed by the detection of linearly polarized radio emission from the HH 80–81 jet,we search for gamma-rays from the HH 80–81 system using ten-year Fermi-LAT observations.A significant point-likeγ-ray excess is found in the direction of the HH80–81 system with the Test-Statistic value>100,which is likely produced in the HH 80–81 ***γ-ray spectrum extends only to 1 Ge V with a photon index of *** significant variability is found in the gamma-ray *** is discussed that the properties of HH 80–81 jet suffice for producing the observedγ-rays.

关键词： gamma-rays:ISM-ISM:jets and outflows radiation mechanisms:non-thermal stars:protostars

Outcome prediction value of National Early Warning Score in septic patients with community-acquired pneumonia in emergency department: A single-center retrospective cohort study

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World Journal of Emergency Medicine 2020年第4期11卷 206-215页

作者： hai-jiang zhou Tian-fei Lan Shu-bin Guo Emergency Medicine Clinical Research Center Beijing Chao-yang HospitalCapital Medical University&Beijing Key Laboratory of Cardiopulmonary Cerebral ResuscitationBeijingChina Department of Allergy Beijing Shijitan HospitalCapital Medical UniversityBeijingChina

BACKGROUND:To evaluate the accuracy of National Early Warning Score(NEWS)in predicting clinical outcomes(28-day mortality,intensive care unit[ICU]admission,and mechanical ventilation use)for septic patients with community-acquired pneumonia(CAP)compared with other commonly used severity scores(CURB65,Pneumonia Severity Index[PSI],Sequential Organ Failure Assessment[SOFA],quick SOFA[qSOFA],and Mortality in Emergency Department Sepsis[MEDS])and admission lactate ***:Adult patients diagnosed with CAP admitted between January 2017 and May 2019 with admission SOFA≥2 from baseline were *** characteristics were *** primary outcome was the 28-day mortality after admission,and the secondary outcome included ICU admission and mechanical ventilation *** prediction value of parameters above was compared using receiver operating characteristics(ROC)*** regression analyses were carried out to determine the risk factors for the 28-day ***-Meier survival curves were plotted and compared using optimal cut-off values of qSOFA and ***:Among the 340 enrolled patients,90 patients were dead after a 28-day follow-up,62 patients were admitted to ICU,and 84 patients underwent mechanical *** single predictors,NEWS achieved the largest area under the receiver operating characteristic(AUROC)curve in predicting the 28-day mortality(0.861),ICU admission(0.895),and use of mechanical ventilation(0.873).NEWS+lactate,similar to MEDS+lactate,outperformed other combinations of severity score and admission lactate in predicting the 28-day mortality(AUROC 0.866)and ICU admission(AUROC 0.905),while NEWS+lactate did not outperform other combinations in predicting mechanical ventilation(AUROC 0.886).Admission lactate only improved the predicting performance of CURB65 and qSOFA in predicting the 28-day mortality and ICU ***:NEWS could be a valuable predictor in septic patients with CAP in emergency depa

关键词： Community-acquired pneumonia Sepsis National Early Warning Score(NEWS) Intensive care unit Emergency departments

Abundant Semigroups with a Quasi-ideal Quasi-adequate Transversal

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Acta Mathematica Sinica,English Series 2009年第10期25卷 1653-1664页

作者： Xiang fei NI Yan Feng LUO hai zhou CHAO Department of Mathematics Lanzhou University Lanzhou 730000 P. R. China Department of Mathematics LongQiao School of Lanzhou Commerical College Lanzhou 730000 P. R. China

Characterization theorems for abundant sernigroups having a quasi-ideal quasi-adequate transversal are obtained. Our results generalize and amplify the related results of Satio on regular semigroup obtained in 1985 and Kong obtained in 2007 respectively. Some recent results on this topic given by Guo-Shum are strengthened. In particular, the structure of such an abundant semigroup is described.

关键词： abundant semigroup quasi-ideal Q-transversal

控制方向未知的受限多智能体系统的预设时间模糊控制

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工程科学学报 2025年第1期47卷 121-129页

作者：李菲周超范利蓉王芳燕山大学理学院秦皇岛066004 河北农业大学海洋学院秦皇岛066003

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-... 详细信息

综合考虑受控制方向未知、输入受限和状态时延影响的有领导者多智能体系统的编队控制问题,设计基于模糊逻辑系统的预设时间一致性控制策略.为了保证编队输出误差在预设时间内满足预定的约束范围要求,引入预设时间性能函数,构造Lyapunov-Krasovskii(L-K)泛函解决状态时延问题,将外界干扰和L-K泛函的导数中的部分项定义为未知非线性函数,并利用模糊逻辑系统对其进行估计,利用Nussbaum函数和均值定理分别处理控制方向未知和输入受限问题,基于以上设计,提出预设时间模糊控制策略,并通过Lyapunov稳定性理论,分析闭环系统的有界稳定性,数值对比仿真和两级化学反应器应用仿真说明控制方法的有效性.

关键词：多智能体系统状态时延输出误差约束输入受限控制方向未知

山姜素调节cAMP/PKA/CREB信号通路促进骨质疏松性骨折大鼠骨折愈合

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中国组织工程研究 2025年第12期29卷 2438-2443页

作者：陆飞周静金涛连云港市第一人民医院康复医学科江苏省连云港市222000 南京医科大学康达学院康复医学部江苏省连云港市222000 中国人民解放军东部战区总医院健康医学科江苏省南京市210018

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作... 详细信息

背景:山姜素具有抗炎、抗肿瘤、抗菌等作用,已被证实能够缓解骨质疏松症,但山姜素对骨质疏松性骨折的影响及机制仍不清楚。目的:探讨山姜素调节环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路对骨质疏松性骨折大鼠的改善作用。方法:采用双侧卵巢切除手术构建骨质疏松症骨折大鼠模型,将成功造模大鼠依据随机数字表法分为山姜素低、中、高剂量组、抑制剂组和模型组,另选12只大鼠作为假手术组。骨折造模当天,山姜素低、中、高剂量组大鼠灌胃7.5,15,30 mg/kg的山姜素+腹腔注射等量的生理盐水,抑制剂组灌胃30 mg/kg的山姜素+腹腔注射5 mg/kg的H-89(通路抑制剂),模型组与假手术组给予(灌胃+腹腔注射)等量生理盐水,1次/d,连续8周。放射性检查评估大鼠骨折愈合情况并进行愈合评分;骨密度扫描仪测定骨折处骨密度;通过三点弯曲实验和压缩实验评估大鼠股骨生物力学状况;苏木精-伊红染色观察大鼠骨折处病理损伤;酶联免疫吸附(ELISA)法检测血清碱性磷酸酶、骨钙素和Ⅰ型胶原交联C-末端肽、环磷酸腺苷水平的变化;Western blot检测股骨组织中骨形态发生蛋白2和环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白通路蛋白表达。结果与结论:①相较于假手术组,模型组大鼠骨折愈合评分、骨密度、最大负荷、最大应力、碱性磷酸酶、骨钙素、环磷酸腺苷水平、骨形态发生蛋白2、磷酸化蛋白激酶A/蛋白激酶A、磷酸化环磷酸腺苷反应元件结合蛋白/环磷酸腺苷反应元件结合蛋白表达下降,Ⅰ型胶原交联羧基末端肽水平增加(P<0.05);与模型组比较,山姜素各剂量组大鼠上述各项指标呈现相反的变化(P<0.05);与山姜素高剂量组比较,抑制剂组大鼠上述指标变化均被逆转(P<0.05)。②结论:山姜素可能通过激活环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白信号通路加速骨质疏松症骨折大鼠的骨折愈合。

关键词：山姜素环磷酸腺苷/蛋白激酶A/环磷酸腺苷反应元件结合蛋白骨质疏松骨折愈合大鼠

INVESTIGATION AND APPLICATION ON GAS-DRIVE DEVELOPMENT IN ULTRA-LOW PERMEABILITY RESERVOIRS

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Journal of Hydrodynamics 2008年第2期20卷 254-260页

作者： ZHAO Ming-guo zhou hai-fei CHEN Ding-feng Key Laboratory of Enhanced Oil and Gas Recovery Minnistry of Education Daqing Petroleum Institute Daqing 163318 China

To select a proper displacement medium with the purpose of developing ultra-low permeability reservoirs both effectively and economically, three kinds of gases, including CO2, NG and N2, are studied through physical modeling and numerical simulation under the specified reservoir conditions. The results indicate that the oil recovery through water injection is relatively low in ultra-low permeability reservoirs, where the water breaks through early and the water cut rises rapidly. Gas injection can enhance the production, of which the gas-drive efficiency depends on the injection pressure and the gas itself. CO2 is proved to be the best one after comprehensive consideration of the recovery speed, the overall recovery efficiency and the time needed for gas to break through. The pressure of CO2 injection in the field experiments is lower, compared with that of water-drive. The injectivity index of CO2 is 7.2 times as high as that of water, and the oil production of the test well group increases by about 4 t/d.

关键词： ultra-low permeability reservoir gas drive physical modeling numerical simulation field experiment