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Anti-inflammatory effects of Solanum procumbens on a low dose complete Freund's adjuvant-induced arthritis rat model

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Asian Pacific Journal of Tropical Biomedicine 2023年第5期13卷 214-221页

作者： Xuan-hai Do Trong Nghia Nguyen Thanh Chung dang Thi Thanh Mai Nguyen Trung Nhan Nguyen Van Nhat Truong Do Huu Tho Le Xuan hai Nguyen hoang Phu dang Giang-linh Nguyen Dinh-Khanh hoang Van-Quan Le Van-Mao Can Department of Practical and Experimental Surgery Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Reconstructive and Microsurgery Craniofacial and Reconstructive Surgery CentreMilitary Central Hospital 108Hanoi 10000Vietnam Department of Anatomic Pathology Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Faculty of Chemistry University of ScienceVietnam National University Ho Chi Minh CityHo Chi Minh City 70000Vietnam Faculty of Medicine University of Medicine and PharmacyVietnam National UniversityHanoi 10000Vietnam Department of Ultrasound Imaging Diagnostics CentreMilitary Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Functional Diagnostics Military Hospital 103Vietnam Military Medical UniversityHanoi 10000Vietnam Department of Pathophysiology Vietnam Military Medical UniversityHanoi 10000Vietnam

Objective:To investigate the anti-inflammatory and analgesic effects of Solanum procumbens on complete Freund’s adjuvantinduced arthritis rat ***:We isolated and identified five compounds in the ethanolsoluble Solanum procumbens extract(SP)with anti-inflammatory effects,including ursolic acid,β-sitosterol,hexadecanoic acid,cisvaccenic acid,and vanillic ***,we investigated the anti-inflammatory effects of SP on rheumatoid arthritis symptoms,including paw volumes,local temperatures,withdrawal latency,and mechanical withdrawal threshold at the hind paw and white blood cell(WBC)number from complete Freund’s adjuvant-induced arthritis rat ***:We have successfully established a complete Freund’s adjuvant-induced arthritis rat model at a low dose(1 mg/mL).SP extract significantly reduced paw volumes(P<0.05),prolonged withdrawal latencies(P<0.05),decreased local temperature,and increased the mechanical withdrawal threshold(P<0.05),but only SP extract at the dose of 300 mg/kg significantly decreased WBC ***:SP extract could be a potential medication candidate with anti-inflammatory effects for arthritis,but it requires further investigation into the mechanism of the SP and its effectiveness on other models as well as clinical trials.

关键词： Solanum procumbens Arthritis Anti-inflammation Complete Freund's adjuvant Rats

Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study

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贫困所致传染病(英文) 2024年第2期13卷 1-12页

作者： Nguyen Hoa Binh Quang Vo Luan Nguyen Forse Rachel Jeanette Wiemers Anja Maria Christine Huynh Huy Ba Dong Thuy Thi Thu Phan Yen Thi hoang Creswell Jacob dang Thi Minh Ha Nguyen Lan Huu Shedrawy Jad L?nnroth Knut Nguyen Tuan Dinh Van Dinh Luong Annerstedt Kristi Sidney Codlin Andrew James National Lung Hospital Ha Noi Viet Nam Friends for International TB Relief Ha Noi Viet Nam Department of Global Public Health WHO Collaboration Centre On Tuberculosis and Social Medicine Karolinska Institute Stockholm Sweden Stop TB Partnership Geneva Switzerland Pham Ngoc Thach Hospital Ho Chi Minh City Viet Nam

Background In Viet Nam, tuberculosis (TB) represents a devastating life-event with an exorbitant price tag, partly due to lost income from daily directly observed therapy in public sector care. Thus, persons with TB may seek care in the private sector for its flexibility, convenience, and privacy. Our study aimed to measure income changes, costs and catastrophic cost incurrence among TB-affected households in the public and private *** Between October 2020 and March 2022, we conducted 110 longitudinal patient cost interviews, among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program (NTP) in Ha Noi, hai Phong and Ho Chi Minh City, Viet Nam. Using a local adaptation of the WHO TB patient cost survey tool, participants were interviewed during the intensive phase, continuation phase and post-treatment. We compared income levels, direct and indirect treatment costs, catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate *** The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort (USD 868 vs USD 578;P=0.010). However, private sector treatment was also significantly costlier (USD 2075 vs USD 1313;P=0.005), driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants (USD 754 vs USD 164;P<0.001). This resulted in no significant difference in catastrophic costs between the two cohorts (Private: 55% vs NTP: 52%;P=0.675). Factors associated with catastrophic cost included being a single-person household [adjusted odds ratio [(aOR=13.71; 95% confidence interval (CI): 1.36–138.14;P=0.026], unemployment during treatment (aOR=10.86; 95%CI: 2.64–44.60;P<0.001) and experiencing TB-related stigma (aOR=37.90; 95%CI: 1.72–831.73;P=0.021).Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the

关键词： Tuberculosis Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam

Ecoregional variations of aboveground biomass and stand structure in evergreen broadleaved forests

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Journal of Forestry Research 2020年第5期31卷 1713-1722页

作者： Tran Van Do Mamoru Yamamoto Osamu Kozan Vo Dai hai Phung Dinh Trung Nguyen Toan Thang Lai Thanh hai Vu Thanh Nam Trieu Thai Hung hoang Van Thang Tran Duc Manh Cao Chi Khiem Vu Tien Lam Nguyen Quang Hung Tran hoang Quy Pham Quang Tuyen Trinh Ngoc Bon Nguyen Thi Thu Phuong Ninh Viet Khuong Nguyen Van Tuan dang Thi hai Ha Tran hai Long dang Van Thuyet dang Thinh Trieu Nguyen Van Thinh Tran Anh hai Duong Quang Trung Nguyen Van Bich Dinh hai dang Pham Tien Dung Nguyen Huy hoang Le Thi Hanh Phan Minh Quang Nguyen Thi Thuy Huong hoang Thanh Son Nguyen Thanh Son Nguyen Thi Van Anh Nguyen Thi Hoai Anh Pham Dinh Sam hoang Thi Nhung hoang Van Thanh Nguyen Huu Thinh Tran Hong Van Ho Trung Luong Bui Kieu Hung Research Institute for Sustainable Humanosphere Kyoto UniversityUjiKyotoJapan Silviculture Research Institute Vietnamese Academy of Forest SciencesNorth Tu LiemHanoiVietnam Center for Southeast Asian Studies Kyoto UniversityKyotoJapan Vietnamese Academy of Forest Sciences North Tu LiemHanoiVietnam Vietnam Administration of Forestry No.2 Ngoc HaBa DinhHanoiVietnam

Biotic and abiotic factors control aboveground biomass(AGB)and the structure of forest *** study analyses the variation of AGB and stand structure of evergreen broadleaved forests among six ecoregions of Vietnam.A data set of 1731-ha plots from 52 locations in undisturbed old-growth forests was *** results indicate that basal area and AGB are closely correlated with annual precipitation,but not with annual temperature,evaporation or hours of *** area and AGB are positively correlated with trees>30 cm *** areas surveyed(52.6%)in these old-growth forests had AGB of 100–200 Mg ha^-1;5.2%had AGB of 400–500 Mg ha^-1,and 0.6%had AGB of>800 Mg ha^-*** percent of the areas surveyed had stand densities of 300–600 ***^-1,and 64%had basal areas of 20–40 m^2 ha^-*** is an important factor influencing the AGB of old-growth,evergreen broadleaved forests in *** causing the loss of large-diameter trees(e.g.,>100 cm DBH)affects AGB but may not seriously affect stand density.

关键词： Aboveground biomass Carbon storage Climatic variables Ecoregion Edaphic variables Oldgrowth forest

Calibration of a neutron dose rate meter in various neutron standard fields

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Nuclear Science and Techniques 2020年第6期31卷 75-82页

作者： Tuan Khai Nguyen Hoai-Nam Tran Quynh Ngoc Nguyen Thi My linh dang Van Loat Bui Thiansin Liamsuwan Ngoc-Thiem Le Vietnam Agency for Radiation and Nuclear Safety 113 Tran Duy HungHanoi 100000Vietnam Institute of Fundamental and Applied Sciences Duy Tan UniversityHo Chi Minh 700000Vietnam Faculty of Natural Sciences Duy Tan University3 Quang TrungDa Nang 550000Vietnam Institute for Nuclear Science and Technology VINATOM179 Hoang Quoc VietHanoi 100000Vietnam Faculty of Physics VNU University of Science334 Nguyen TraiHanoi 100000Vietnam Nuclear Research and Development Division Thailand Institute of Nuclear TechnologyOngkharakNakorn NayokThailand 7 Faculty of Medicine and Public HealthHRH Princess Chulabhorn College of Medical ScienceChulabhorn Royal AcademyBangkokThailand

This paper presents the calibration of a neutron dose rate meter and the evaluation of its calibration factors(CFs)in several neutron standard fields(i.e.,two standard fields with bare sources of252Cf and241Am-Be,and five simulated workplace fields with241Am-Be moderated sources).The calibration in standard fields with bare sources was conducted by following the recommendations of the ISO 8529 *** measured total neutron ambient dose equivalent rates,denoted as H*(10)tot,were analyzed to obtain direct components,denoted as H*(10)dir,using a reduced fitting *** CF was then calculated as the ratio between the conventional true value of the neutron ambient dose equivalent rate in a free field,denoted as H*(10)FF,and the value of H*(10)*** contrast,in the simulated workplace neutron fields,the calibration of the neutron dose rate meter was conducted by following the ISO 12789 *** CF was calculated as the ratio between the values of H*(10)totmeasured by a standard instrument(i.e.,Bonner sphere spectrometer)and the neutron dose rate *** CF values were obtained in the range of 0.88–*** standard uncertainties(k=1)of the CFs were determined to be in the range of approximately 6.6–13.1%.

关键词： Neutron standard fields Neutron dose rate meter Calibration factor 252Cf source 241AmBe source

Biomass accumulation of Panax vietnamensis in cell suspension cultures varies with addition of plant growth regulators and organic additives

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Asian Pacific Journal of Tropical Medicine 2017年第9期10卷 907-915页

作者： Tuan Tran Trong Dieu-Hien Truong hoang Chinh Nguyen Dieu-Thai Tran Huyen-Trang Nguyen Thi Giap Do dang Ho Nguyen Huu Plant Cell Technology Department Institute of Tropical BiologyVietnam Academy of Science and Technology9/621 Ha Noi HighwayLinh TrungThu DucHo Chi Minh CityViet Nam Faculty of Applied Sciences Ton Duc Thang University19 Nguyen Huu ThoTan PhongDistrict 7Ho Chi Minh CityViet Nam Genetic Engineering Department Institute of Tropical BiologyVietnam Academy of Science and Technology9/621 Ha Noi HighwayLinh TrungThu DucHo Chi Minh CityViet Nam

Objective: To evaluate the impact of plant growth regulators including kinetin(KN),benzyl adenine and naphthalene acetic acid, yeast extract and casein hydrolyzate on biomass accumulation of Vietnamese ginseng Panax vietnamensis(P. vietnamensis) in cell suspension ***: Cell suspension cultures were established from friable calluses derived from leaves and petioles of 3-year-old in-vitro P. vietnamensis plants. The cell suspension cultures were grown in Murashige and Skoog basal media supplemented with various concentrations of KN, benzyl adenine, naphthalene acetic acid, and yeast extract and casein ***: All tested factors generated an increase in the cell biomass of P. vietnamensis in suspension culture, but the impact of each varies depended on the factor type, concentration, and incubation period. Addition of 2.0 mg/L KN resulted in the largest biomass increase after 24 d,(57.0 ± 0.9) and(3.1 ± 0.1) mg/m L fresh and dry weight, respectively,whereas addition of benzyl adenine or naphthalene acetic acid produced optimum levels of Panax cell biomass at 1.0 and 1.5 mg/L, respectively. Addition of the elicitor yeast extract led to a 1.4–2.4 fold increase in biomass of P. vietnamensis, while addition of casein hydrolyzate enhanced biomass accumulation 1.8–2.6 ***: The addition of each factor causes significant changes in biomass accumulation of P. vietnamensis. The largest biomass accumulation is from cultures grown in MS media containing 2.0 mg/L KN for 24 d. The outcome of the present study provides new insights into the optimal suspension culture conditions for studies on the in vitro cell biomass production of P. vietnamensis.

关键词： Panax vietnamensis Plant cell suspension culture Plant regulators Yeast extract Casein hydrolyzate Biomass

Green synthesis of three-dimensional magnesium ferrite/titanium dioxide/reduced graphene from Garcinia mangostana extract for crystal violet photodegradation and antibacterial activity

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Journal of Semiconductors 2023年第12期44卷 111-124页

作者： Tong hoang Lin Che Quang Cong Nguyen Thanh Hoai Nam hoang An Nguyen Duy hai Ton That Buu Thoi Le Nhat Binh hoang Le Minh Lam Thanh Ngan hoang Thuy Kim Ngan Du Chi Vi Ta dang Khoa Nguyen Huu Hieu VNU-HCM Key Laboratory of Chemical Engineering and Petroleum Processing(Key CEPP Lab)Ho Chi Minh City University of Technology(HCMUT)268 Ly Thuong Kiet StreetDistrict 10Ho Chi Minh CityVietnam Faculty of Chemical Engineering Ho Chi Minh City University of Technology(HCMUT)268 Ly Thuong Kiet StreetDistrict 10Ho Chi Minh CityVietnam Vietnam National University Ho Chi Minh City(VNU-HCM) Linh Trung WardThu Duc CityVietnam

In this study,three-dimensional porous magnesium ferrite/titanium dioxide/reduced graphene oxide(Mg Fe_2O_(4)-GM/TiO_(2)/rGO(MGTG))was successfully synthesized via green and hydrothermal-supported co-precipitation methods using the extract of Garcinia mangostana(***)as a reducing *** characterization results indicate the successful formation of the nano/micro Mg Fe_(2)O_(4)(MFO)and TiO_(2) on the structure of the reduced graphene oxide(rGO),which can also act as efficient support,alleviating the agglomeration of the nano/micro MFO and TiO_(2).The synergic effects of the adsorption and photodegradation activity of the material were investigated according to the removal of crystal violet(CV)under ultraviolet *** effects of catalyst dosage,CV concentration,and p H on the CV removal efficiency of the MGTG were also *** to the results,the CV photodegradation of the MGTG-200 corresponded to the pseudo-first-order kinetic *** reusability of the material after 10 cycles also showed a removal efficiency of 92%.This happened because the materials can easily be recollected using external *** addition,according to the effects of different free radicals·O_(2)^(-),h^(+),and·OH on the photodegradation process,the photocatalysis mechanism of the MGTG was also thoroughly *** antibacterial efficiency of the MGTG was also evaluated according to the inhibition of the Gram-positive bacteria strain Staphylococcus aureus(***).Concurrently,the antibacterial mechanism of the fabricated material was also *** results confirm that the prepared material can be potentially employed in a wide range of applications,including wastewater treatment and antibacterial activity.

关键词： magnesium ferrite titanium dioxide reduced graphene oxide Garcinia mangostana photodegradation antibacterial

Nutritional status of Vietnamese infants assessed by Fenton growth chart and related factors:A cross-sectional study

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Pediatric Investigation 2023年第4期7卷 254-262页

作者： Lieu Thu Thi Nguyen Cuong Danh Tran Ha Thu Thi Nguyen hai Thanh Phan linh Thuy Nguyen Huong Lan Thi Nguyen Anh Hoai Thi Ta Chau Quynh Thi Pho Khanh Nam Do Anh Kim dang Huong Thi Le School of Preventive Medicine and Public Health Hanoi Medical UniversityHanoiVietnam Department of Nutrition National Hospital of Obstetrics and GynecologyHanoiVietnam Department of General Obstetrics National Hospital of Obstetrics and GynecologyHanoiVietnam Department of Nutrition and Dietetics Hanoi Medical University HospitalHanoiVietnam Queensland Alliance for Environmental Health Sciences(QAEHS) The University of QueenslandBrisbaneAustralia

Importance:Nutritional status of infants,measured by birth weight and length,is an essential factor in neonatal *** in newborns may lead to a higher risk of mortality,neurological and cognitive impairment,and poor language ***:This study aims to assess the nutritional status of infants and related factors regarding maternal anthropometric characteristics and medical ***:A cross-sectional study was conducted at the National Hospital of Obstetrics and Gynecology,Vietnam from May 2021 to May 2022 on 340 infants and *** birth weight was defined following the Intergrowth-21 *** was evaluated using the Fenton growth chart when the length was below the 10%percentile line of the gestational *** regression models were applied to identify factors associated with the nutritional status of ***:We found that 12.4%and 14.1%of infants in our study fell into stunted and underweight categories,*** of mothers over 35 years old,having a height lower than 150 cm or experiencing anemia during pregnancy were more likely to be stunted or have low birth *** albumin deficiency during pregnancy was strongly associated with the infant being underweight(odds ratio[OR]=2.8,95%confidence interval[95%CI]1.1–7.3).Newborns were more likely to be stunted if their mothers had a history of preterm birth(OR=3.3,95%CI 1.1–10.2).Interpretation:Maternal nutritional status is closely related to infant malnutrition,particularly in preterm *** the understanding of mothers regarding prenatal care,reproductive healthcare,adequate nutritional diet,and multi-micronutrient supplements during pregnancy is therefore important.

关键词： Fenton chart Infant Low birth weight Stunting Underweight

Factors Affecting the Entrepreneurial Intention of Students at Tan Trao University

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Macro Management & Public Policies 2023年第2期5卷 34-44页

作者： hoang Anh Dao Chu Thanh Mai Phi Tra My Phan Huyen linh Le hai Yen Faculty of Economics and Business Administration Tan Trao UniversityYenson DistrictTuyen Quang Province300000Vietnam

Entrepreneurship is one of the popular choices for students after graduation from higher *** study focuses on proposing a model to identify the factors affecting the entrepreneurial intention of students at Tan Trao University by researching some typical models in the *** quantitative research methods based on a survey of 391 students,the study has shown that there are 5 factors affecting the entrepreneurial intention of students at Tan Trao University,including opportunity,motivation,perception of behavioral control,skills and resources for ***,the study proposes a number of solutions for the students,the university and other related parties to promote students’entrepreneurial intentions.

关键词： Factors Entrepreneurial intention Students Tan Trao University

Assessing and Forecasting Saline Intrusion in theVietnamese Mekong Delta Under the Impact of Upstreamflow and Sea Level Rise

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Journal of Environmental Science and Engineering(B) 2019年第5期8卷 174-185页

作者： Tran Xuan hai Vu Van Nghi Vu hoang Hung Do Ngoc Tuan dang Thanh Lam Can Thu Van Institute for Science and Technology Innovation Ho Chi Minh City 700000Vietnam University of Science Vietnam National UniversityHo Chi Minh City 700000Vietnam Thuyloi University Ha No 100000Vietnam Southern Institute for Water Resources Planning Ho Chi Minh City 700000Vietnam Ho Chi Minh City University of Natural Resources and Environment Ho Chi Minh City 700000Vietnam

Saline intrusion is a hot issue and has always been of concern in the VMD(Vietnamese Mekong Delta),especially in the context of many changes of impact factors such as upstream flows and SLR(Sea Levels Rise).Vulnerability to changes in the upstream flows and SLR ismust-have reasons for updated and interpreted *** information is used for exploiting of soil and water *** 11 model was successfully applied to assess the saline *** study provided the picture of the saline intrusion in the dry season from January to May in the VMD in the existing situation(2015 and 2016)and the future(2030 and 2050)under the impact of flow at Kratie in various frequencies of 18%,50%and 85%based on the time series of 2001-2016,and SLR according to RCP(Representative Concentration Pathway)4.5 scenario of MONRE(Ministry of Natural Resources and Environment)of Vietnam issued in *** results show that in the year 2015 the ASI(Saline Intrusion Area)in the VMD was relatively low due to moderate tidal level and high Kratie discharge(P=18%).The scenario like the situation in 2016 and in the future ASI increased significantly compared to the 2015 baseline scenario which shows that the VMD is very vulnerable to saline *** on multivariate regression analysis,the study also presented the formulas for the relationship between the ASI of 0.25 g/L,2.5 g/L and 4.0 g/L thresholds and the impact factors such as the average discharge at Kratie and the maximum daily tidal level in East Coast during the dry season from January to *** an adjusted R2 at 0.913-0.974,these formulas are believed to be reliable for predicting ASIs based on the Kratie flow and the East Coast tidal level.

关键词： Saline intrusion sea level rise upstream flow VMD