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Preoperatively predicting vessels encapsulating tumor clusters in hepatocellular carcinoma:Machine learning model based on contrast-enhanced computed tomography

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 857-874页

作者： Chao Zhang hai zhong Fang Zhao Zhen-Yu Ma Zheng-Jun Dai Guo-Dong Pang Department of Radiology The Second Hospital of Shandong UniversityJinan 250033Shandong ProvinceChina Department of Radiology Qilu Hospital of Shandong UniversityJinan 250014Shandong ProvinceChina Department of Radiology Linglong Yingcheng HospitalYantai 265499Shandong ProvinceChina Department of Scientific Research Huiying Medical Technology Co.LtdBeijing 100192China

BACKGROUND Recently,vessels encapsulating tumor clusters(VETC)was considered as a distinct pattern of tumor vascularization which can primarily facilitate the entry of the whole tumor cluster into the bloodstream in an invasion independent manner,and was regarded as an independent risk factor for poor prognosis in hepatocellular carcinoma(HCC).AIM To develop and validate a preoperative nomogram using contrast-enhanced computed tomography(CECT)to predict the presence of VETC+in *** We retrospectively evaluated 190 patients with pathologically confirmed HCC who underwent CECT scanning and immunochemical staining for cluster of differentiation 34 at two medical *** analysis was conducted on intratumoral and peritumoral regions in the portal vein *** features,essential for identifying VETC+HCC,were extracted and utilized to develop a radiomics model using machine learning algorithms in the training *** model’s performance was validated on two separate test *** operating characteristic(ROC)analysis was employed to compare the identified performance of three models in predicting the VETC status of HCC on both training and test *** most predictive model was then used to constructed a radiomics nomogram that integrated the independent clinical-radiological *** and decision curve analysis were used to assess the performance characteristics of the clinical-radiological features,the radiomics features and the radiomics *** The study included 190 individuals from two independent centers,with the majority being male(81%)and a median age of 57 years(interquartile range:51-66).The area under the curve(AUC)for the combined radiomics features selected from the intratumoral and peritumoral areas were 0.825,0.788,and 0.680 in the training set and the two test sets.A total of 13 features were selected to construct the *** nomogram,combining clinicalradiological and combined radiomics features could acc

关键词： Hepatocellular carcinoma Vessels encapsulating tumor clusters Intratumoral and peritumoral regions Radiomics features Nomog

Pulsations of Three Rapidly Oscillating Ap Stars TIC 96315731, TIC72392575, and TIC 318007796

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Research in Astronomy and Astrophysics 2024年第8期24卷 159-170页

作者： hai-Jian zhong Dong-Xiang Shen Chun-Hua Zhu He-Lei Liu Su-Fen Guo Guo-Liang Lü School of Physical Science and Technology Xinjiang University Xinjiang Astronomical Observatory National Astronomical ObservatoriesChinese Academy of Sciences

We analyze the frequencies of three known roAp stars,TIC 96315731,TIC 72392575,and TIC 318007796,using the light curves from the Transiting Exoplanet Survey *** TIC 96315731,the rotational and pulsational frequencies are 0.1498360 day-1and 165.2609 day-1,*** the case of TIC 72392575,the rotational frequency is 0.25551 *** detect a quintuplet of pulsation frequencies with a center frequency of135.9233 day-1,along with two signals within the second pair of rotational sidelobes of the quintuplet separated by the rotation *** two signals may correspond to the frequencies of a dipole *** TIC318007796,the rotational and pulsational frequencies are 0.2475021 day-1,192.73995 day-1,and196.33065 day-1,*** on the oblique pulsator model,we calculate the rotation inclination （i）and magnetic obliquity angle （b） for the stars,which provide the geometry of the pulsation *** the phases of the frequency quintuplets,the pulsation amplitude and phase modulation curves,and the results of spherical harmonic decomposition,we conclude that the pulsation modes of frequency quintuplets in TIC96315731,TIC 72392575,and TIC 318007796 correspond to distorted dipole mode,distorted quadrupole mode,and distorted dipole mode,respectively.

关键词： asteroseismology stars: chemically peculiar stars: oscillations (including pulsations) techniques: photometric

Boosting ammonia production in electrocatalytic NO_(x)reduction on a robust Fe/FeMoO_(4)catalyst

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Nano Research 2024年第7期17卷 5801-5806页

作者： Dong-Xue Liu Xin Deng Yong-Fu Zhu Zhe Meng Xue-Feng Sun Miao-Miao Shi hai-Xia zhong Jun-Min Yan Key Laboratory of Automobile Materials Ministry of EducationSchool of Materials Science and EngineeringJilin UniversityChangchun 130022China State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

Electrocatalytic reduction of nitrate(NO_(3)^(−))and nitride(NO_(2)^(−))to ammonia(NH3)is of wide interest as a promising alternative to the energy-intensive Haber-Bosch route for mitigating the vast energy consumption and the accompanied carbon dioxide emission,as well as benefiting for the relevant sewage ***,exploring an efficient and low-cost catalyst with high atomic utilization that can effectively facilitate the slow multi-electron transfer process remains a grand ***,we present an efficient hydrogenation of NO_(3)^(−)/NO_(2)^(−)species to NH3 in both alkaline and neutral environments over the Fe_(2)(MoO_(4))_(3)derived hybrid electrocatalyst with the metallic Fe site on FeMoO_(4)(Fe/FeMoO_(4)).The Mo ingredient can play a synergistically positive role in further promoting the NH_(3) production on *** a result,Fe/FeMoO_(4)behaves well in the electrochemical NH_(3) generation from NO_(2)^(−)with a maximum NH_(3) Faradaic efficiency(FE)of 96.53%and 87.68%in alkaline and neutral electrolyte,corresponding to the NH_(3) yield rate of 640.68 and 302.56 mg·h^(−1)·mg_(cat.)^(−1),respectively,which outperforms the Fe and Mo counterpart and other similar catalyst,showing the robust catalytic capacity of each active site.

关键词： ammonia synthesis NO_(x)reduction synergistic effect alkaline/neutral electrolyte

Efficacy and safety of targeted therapy plus immunotherapy combined with hepatic artery infusion chemotherapy (FOLFOX) for unresectable hepatocarcinoma

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World Journal of Gastroenterology 2024年第17期30卷 2321-2331页

作者： Zhi-Peng Lin Xiao-Long Hu Du Chen Da-Bei Huang Xu-Gong Zou hai zhong Sheng-Xiang Xu Yuan Chen Xiao-Qun Li Jian Zhang Department of Interventional Medicine Zhongshan People’s HospitalZhongshan 528400Guangdong ProvinceChina

BACKGROUND The advent of cutting-edge systemic therapies has driven advances in the treatment of hepatocellular carcinoma(HCC),and therapeutic strategies with multiple modes of delivery have been shown to be more efficacious than ***,the mechanisms underlying this innovative treatment modality have not been *** To evaluate the clinical efficacy of targeted therapy plus immunotherapy combined with hepatic arterial infusion chemotherapy(haiC)of FOLFOX in patients with unresectable *** We enrolled 53 patients with unresectable HCC who received a combination of targeted therapy,immunotherapy,and haiC of FOLFOX between December 2020 and June 2021 and assessed the efficacy and safety of the treatment *** The objective response rate was 60.4%(32/53),complete response was 24.5%(13/53),partial response was 35.9%(19/53),and stable disease was 39.6%(21/53).The median duration of response and median progression-free survival were 9.1 and 13.9 months,*** surgical conversion rate was 34.0%(18/53),and 1-year overall survival was 83.0%without critical complicating diseases or adverse events(AEs).CONCLUSION The regimen of haiC of FOLFOX,targeted therapy,and immunotherapy was curative for patients with unresectable HCC,with no serious AEs and a high rate of surgical conversion.

关键词： Hepatocellular carcinoma Hepatic arterial infusion chemotherapy Targeted therapy Immunotherapy Adverse events

Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children:analysis of 571 patients

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World Journal of Pediatrics 2024年第3期20卷 250-258页

作者： Min He Jia-Bin Cai Xuan Wu Yin-Bing Tang Jin-Yan Wang Jun-Qin Mao Ji-Jun Chen Li-Feng Zhang zhong-hai Guan Jie-Ni Xiong Wan-Xin Peng Jin-Hu Wang Ting Tao Pediatric Cancer Research Center National Clinical Research Center for Child HealthHangzhouChina Department of Surgical Oncology Children's HospitalZhejiang University School of MedicineHangzhouChina Cancer Center Zhejiang UniversityNo.3333 Binsheng RodeHangzhouChina

Background Surgery plays an important role in the treatment of *** complications may impact the course of neuroblastoma *** date,comprehensive analyses of complications and risk factors have been *** Patients with retroperitoneal neuroblastoma undergoing tumor resection were retrospectively analyzed between 2014 and *** data collected included clinical characteristics,operative details,operative complications and postopera-tive *** factors for perioperative complications of retroperitoneal neuroblastoma were *** A total of 571 patients were enrolled in this *** complications were observed in 255(44.7%)*** leakage(28.4%),diarrhea(13.5%),and injury(vascular,nerve and organ;7.5%)were the most frequent *** were three operation-related deaths(0.53%):massive hemorrhage(n=1),biliary tract perforation(n=1)and intestinal necrosis(n=1).The presence of image-defined risk factors(IDRFs)[odds ratio(OR)=2.09,P<0.01],high stage of the International Neuroblastoma Risk Group staging system(INRGSS)(OR=0.454,P=0.04),retroperitoneal lymph node metastasis(OR=2.433,P=0.026),superior mesenteric artery encasement(OR=3.346,P=0.003),and inferior mesenteric artery encasement(OR=2.218,P=0.019)were identified as independent risk factors for perioperative *** Despite the high incidence of perioperative complications,the associated mortality rate was quite ***-perative complications of retroperitoneal neuroblastoma were associated with IDRFs,INRGSS,retroperitoneal lymph node metastasis and vascular *** with high-risk factors should receive more serious attention during surgery but should not discourage the determination to pursue total resection of neuroblastoma.

关键词： Complication Neuroblastoma Risk factors Surgery

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无限与一体:重构魏晋思想的一种可能

中山大学学报（社会科学版） 2024年第1期64卷 133-142页

作者：胡海忠中国社会科学院哲学研究所北京100871

基于整体性—个体性、无限性—有限性这一解释框架,可对魏晋思想进行重新刻画。以风俗、制度为表征的整体性秩序的扭曲和破裂,导致汉末魏晋时期个体性被突出强调。为避免对个体性的深刻理解走向个人主义、虚无主义,玄学家提出两种理性方... 详细信息

基于整体性—个体性、无限性—有限性这一解释框架,可对魏晋思想进行重新刻画。以风俗、制度为表征的整体性秩序的扭曲和破裂,导致汉末魏晋时期个体性被突出强调。为避免对个体性的深刻理解走向个人主义、虚无主义,玄学家提出两种理性方案:将个体视域从政治社会扩大到天地万物的整体,以至大无外的“一体”化解有限性焦虑;以“无限”作为克服有限的支点,寻求在有限的立场上通向无限的可能性。形神、礼乐、生死、公私、自然与名教、独化与玄同、有无、儒道等都是在“无限”“一体”逻辑中展开的分议题。这一奠定魏晋思想走向的深层逻辑在郭象那里充分展开:变化的绝对性意味着个体无法外在于变化,所以个体必然与变化为一体;变化的绝对性还意味着变化是无限的,所以与变化为一体的个体也应该是无限的。在“以天下为一体”的整体感与自生独化的主体自觉中实现的“自得”,可能是魏晋玄学为宋明理学留下的一个宝贵启示。

关键词：魏晋玄学《世说新语》郭象嵇康自得

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农村水利工程施工管理问题及对策

生成式人工智能意识形态风险:逻辑审视、样态呈现及防范对策

建筑与装饰 2024年第6期 64-66页

作者：王中海淮南市潘集区水利局安徽淮南 232092

农村、农业现代化趋势下各农业地区陆续兴建了各种规模及类型的水利工程,这些工程对农业生产等具有不可替代的作用.多年来,我国在农村水利工程建设中积累了大量的工程经验,有利于提高农村水利工程的质量、安全.虽农村水利工程施工技术... 详细信息

农村、农业现代化趋势下各农业地区陆续兴建了各种规模及类型的水利工程,这些工程对农业生产等具有不可替代的作用.多年来,我国在农村水利工程建设中积累了大量的工程经验,有利于提高农村水利工程的质量、安全.虽农村水利工程施工技术越发成熟,但施工管理方面的问题突出,不利于项目建设,未来需着重创新农村水利工程施工管理理念及方法.基于此,本文着重分析了农村水利工程施工管理问题,提出了相应的改进对策,以期为同类型项目提供参考.

关键词：农村水利工程施工管理改进对策

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党政研究 2024年第4期 14-22,124页

作者：钟海齐冰北京体育大学马克思主义学院北京100084

生成式人工智能与意识形态高度关联。从技术特性来看,意识形态传播样态改变、意识形态管理难度增大、技术特性虚化意识形态阶级属性三个层面是其意识形态风险的底层逻辑。生成式人工智能,在生成内容方面存在疏离主流意识形态理论体系风... 详细信息

生成式人工智能与意识形态高度关联。从技术特性来看,意识形态传播样态改变、意识形态管理难度增大、技术特性虚化意识形态阶级属性三个层面是其意识形态风险的底层逻辑。生成式人工智能,在生成内容方面存在疏离主流意识形态理论体系风险,在技术表现形式上弱化主流意识形态主导权,在传播范围上挤占传播空间等是其意识形态风险的主要呈现样态。为了应对这些意识形态风险,我们应加强制度保障,充分发挥马克思主义在意识形态领域指导地位的根本优势;通过理论引领强化重点群体教育;加快核心技术和意识形态关联性技术研发;完善行业发展规范,不断提升对生成式人工智能技术意识形态风险的防控能力。

关键词：生成式人工智能意识形态信息茧房 Sora

场域理论视域下的情报政治化:逻辑、机理与矫正路径

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情报杂志 2024年第2期43卷 18-24页

作者：孙曲宜钟海国防科技大学国际关系学院南京210039

[研究目的]场域理论作为经典的社会实践理论,其理论框架与情报工作具有一定的契合性,从场域理论角度对情报工作中的政治化问题进行剖析梳理,对于该问题的理论创新与策略探讨具有现实意义。[研究方法]情报政治化本质上是情报权力的失范,... 详细信息

[研究目的]场域理论作为经典的社会实践理论,其理论框架与情报工作具有一定的契合性,从场域理论角度对情报工作中的政治化问题进行剖析梳理,对于该问题的理论创新与策略探讨具有现实意义。[研究方法]情报政治化本质上是情报权力的失范,表现为情报权力的弃用与滥用。采用跨学科研究法,借鉴场域理论“场域”“资本”和“惯习”三个核心视角分析政治化主体背后的实践逻辑,系统分析其产生机理,并对矫正路径的可行性进行研讨。[研究结论]场域理论背景下,情报政治化是场域独立缺失、资本争夺、惯习潜沉共同作用的结果,在此基础上,可以从重构情报决策场域边界、加强情报体制机制创新、明确价值导向、引入技术搭建决策情报系统等方面对情报政治化进行防范与矫正。

关键词：情报工作情报政治化场域理论情报权力