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Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

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World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun huang Zhu Chen Heng Xiao hai-Yang hu Xing-Yu Chen Cheng-You Du Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control

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Superconducting gap opens fully in the newly found topological kagome metal CsV_(3)Sb_(5)

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Science China(Physics,Mechanics & Astronomy) 2021年第10期64卷 21-22页

作者： hai-hu Wen National Laboratory of Solid State Microstructures and Department of Physics Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China

Compounds with kagome lattices can accommodate several kinds of novel quantum states, such as the quantum spin liquid, non-trivial topological Dirac bands, and strongly renormalized flat bands, which may lead to vario... 详细信息

关键词： properties. topological bands

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Specific heat in superconductors

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Chinese Physics B 2020年第1期29卷 24-39页

作者： hai-hu Wen School of Physics Nanjing UniversityNanjing 210093China

Specific heat is a powerful tool to investigate the physical properties of condensed *** state is achieved through the condensation of paired electrons,namely,the Cooper *** condensed Cooper pairs have lower entropy compared with that of electrons in normal metal,thus specific heat is very useful in detecting the low lying quasiparticle excitations of the superconducting condensate and the pairing symmetry of the superconducting *** this brief overview,we will give an introduction to the specific heat investigation of the physical properties of *** show the data obtained in cuprate and iron based superconductors to reveal the pairing symmetry of the order parameter.

关键词： specific heat gap symmetry low lying quasiparticle excitations cuprates iron based superconductors

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Local Least Product Relative Error Estimation for Varying Coefficient Multiplicative Regression Model

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Acta Mathematicae Applicatae Sinica 2019年第2期35卷 274-286页

作者： Da-hai hu School of Management University of Science and Technology of China

In this article, we consider the varying coefficient multiplicative regression model, which is very useful to model the positive response. The criterion of least product relative error(LPRE) is extended to the varying coefficient multiplicative regression model by kernel smoothing techniques. Consistency and asymptotic normality of the proposed estimator are established. Some numerical simulations are carried out to assess the performance of the proposed estimator. As an illustration, the ethanol data is analyzed.

关键词： varying coefficient model multiplicative regression model relative error kernel smoothing

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Comparative study of vortex dynamics in CaKFe_4As_4 and Ba_(0.6)K_(0.4)Fe_2As_2 single crystals

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Science Bulletin 2019年第2期64卷 81-90页

作者： Wang Cheng hai Lin Bing Shen hai-hu Wen Center for Superconducting Physics and Materials National Laboratory of Solid State Microstructures and Department of Physics National Center of Microstructures and Quantum Manipulation Nanjing University School of Physics Sun Yat-sen University

We investigate the vortex dynamics in two typical hole doped iron based superconductors CaKFe_4As_4(CaK1144) and Ba_(0.6)K_(0.4)Fe_2As_2(BaK122) with similar superconducting transition temperatures. It is found that the magnetization hysteresis loop exhibits a clear second peak effect in BaK122 in wide temperature region while it is absent in CaK1144. However, a second peak effect of critical current density versus temperature is observed in CaK1144, which is however absent in BaK122. The different behaviors of second peak effect in BaK122 and CaK1144 may suggest distinct origins of vortex pinning in different systems. Magnetization and its relaxation have also been measured by using dynamical and conventional relaxation methods for both systems. Analysis and comparison of the two distinct systems show that the vortex pinning is stronger and the critical current density is higher in BaK122 system. It is found that the Maley's method can be used and thus the activation energy can be determined in BaK122 by using the time dependent magnetization in wide temperature region, but this is not applicable in CaK1144 *** we present the different regimes with distinct vortex dynamics in the field-temperature diagram for the two systems.

关键词： CaKFe4As4 Ba0.6K0.4Fe2As2 Magnetization hysteresis loop Vortex pinning Second peak effect Vortex dynamics

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Active flow control using machine learning:A brief review

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Journal of Hydrodynamics 2020年第2期32卷 247-253页

作者： Feng Ren hai-bao hu hui Tang Research Center for Fluid-Structure Interactions Department of Mechanical EngineeringThe Hong Kong Polytechnic UniversityHong KongChina School of Marine Science and Technology Northwestern Polytechnical UniversityXi’an710072China

Nowadays the rapidly developing artificial intelligence has become a key solution for problems of diverse disciplines,especially those involving big *** in these areas also attract researchers from the community of fluid mechanics,especially in the field of active flow control(AFC).This article surveys recent successful applications of machine learning in AFC,highlights general ideas,and aims at offering a basic outline for those who are interested in this specific *** this short review,we focus on two methodologies,i.e.,genetic programming(GP)and deep reinforcement learning(DRL),both having been proven effective,efficient,and robust in certain AFC problems,and outline some future prospects that might shed some light for relevant studies.

关键词： Active flow control(AFC) machine learning genetic programming(GP) deep reinforcement learning(DRL)

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Fluorogen-activating proteins: beyond classical fluorescent proteins

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Acta Pharmaceutica Sinica B 2018年第3期8卷 339-348页

作者： Shengnan Xu hai-Yu hu State Key Laboratory of Bioactive Substances and Function of Natural Medicine Institute of Materia Medica Peking Union Medical College and Chinese Academy of Medical Sciences Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation Institute of Materia Medica Peking Union Medical College and Chinese Academy of Medical Sciences

Fluorescence imaging is a powerful technique for the real-time noninvasive monitoring of protein dynamics. Recently, fluorogen activating proteins(FAPs)/fluorogen probes for protein imaging were developed. Unlike the traditional fluorescent proteins(FPs), FAPs do not fluoresce unless bound to their specific small-molecule fluorogens. When using FAPs/fluorogen probes, a washing step is not required for the removal of free probes from the cells, thus allowing rapid and specific detection of proteins in living cells with high signal-to-noise ratio. Furthermore, with different fluorogens, living cell multi-color proteins labeling system was developed. In this review, we describe about the discovery of FAPs, the design strategy of FAP fluorogens, the application of the FAP technology and the advances of FAP technology in protein labeling systems.

关键词： Fluorogen activating proteins Fluorogens Genetically encoded sensors Fluorescence imaging Molecular imaging

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Deployment dynamics of a simplified spinning IKAROS solar sail via absolute coordinate based method

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Acta Mechanica Sinica 2013年第1期29卷 132-142页

作者： Jing Zhao hai-Yan hu Qiang Tian State Key Lab of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and Astronautics School of Aerospace Engineering Beijing Institute of Technology

The spinning solar sail of large scale has been well developed in recent years. Such a solar sail can be considered as a rigid-flexible multibody system mainly composed of a spinning central rigid hub, a number of flexible thin tethers, sail membranes, and tip masses. A simplified interplanetary kite-craft accelerated by radiation of the Sun （IKAROS） model is established in this study by using the absolute-coordinate-based （ACB） method that combines the natural coordinate formulation （NCF） describing the central rigid hub and the absolute nodal coordinate formulation （ANCF） describing flexible parts. The initial configuration of the system in the second-stage deployment is determined through both dynamic and static analyses. The huge set of stiff equations of system dynamics is solved by using the generalized-alpha method, and thus the deployment dynamics of the system can be well understood.

关键词： Solar sail · Spinning deployment - Natural coordinate formulation Absolute nodal coordinate formulation

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World Journal of Emergency Medicine 2022年第6期13卷 425-432页

作者： hai hu Ni Yao Xiao-qin Lai Emergency Management Office of West China Hospital Sichuan UniversityChengdu 610041China China International Emergency Medical Team Chengdu 610041China Sichuan University’s Emergency Medical Rescue Base Chengdu 610041China Department of Critical Care Medicine West China HospitalSichuan UniversityChengdu 610041China Day Surgery Center West China HospitalSichuan UniversityChengdu 610041China West China School of Nursing Sichuan UniversityChengdu 610041China

BACKGROUND:There is limited evidence for emergency physicians and emergency trauma surgeons regarding the determinants of early and rapid assessment of older adult in-hospital mortality due to *** study explored factors related to the early and rapid assessment of the mortality among older adult earthquake trauma patients(OAETPs)and created a screening ***:Data on 7,308 OAETPs from the West China Earthquake Patients Database were analyzed *** 35 variables that can be obtained rapidly on arrival at the hospital were *** absolute shrinkage and selection operator(LASSO)regression analysis was ***,the nomogram for assessing the mortality of OAETPs was ***:We identified 10 independent mortality-related factors that contributed to the in-hospital mortality of *** 10 factors included age(odds ratio[OR]=1.061,95%confidence interval[CI]:1.031-1.090),dementia(OR=5.146,95%CI:1.169-17.856),coronary heart disease(CHD;OR=23.441,95%CI:4.799-83.927),malignant tumor(OR=8.497,95%CI:3.583-17.967),deep vein thrombosis(DVT;OR=7.110,95%CI:1.369-27.168),chronic kidney disease(CKD;OR=11.783,95%CI:5.419-24.407),pulse rate(PR;OR=1.036,95%CI:1.022-1.048),mean artery pressure(MAP;OR=0.960,95%CI:0.945-0.975),Glasgow Coma Scale(GCS;OR=0.864,95%CI:0.760-0.972),and Triage Revised Trauma Score(T-RTS,OR=0.485,95%CI:0.351-0.696).CONCLUSION:The 10 mortality-related factors could be quickly obtained on hospital arrival and should be the focal point of future earthquake response strategies regarding hospitalized older adults with trauma.A nomogram was constructed based on the factors for screening OAETPs with a higher risk of in-hospital mortality.

关键词： Trauma Mortality Earthquakes Elderly patients

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Comparison of different versions of the quick sequential organ failure assessment for predicting in-hospital mortality of sepsis patients:A retrospective observational study

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World Journal of Emergency Medicine 2022年第2期13卷 114-119页

作者： hai hu Jing-yuan Jiang Ni Yao Emergency Office of West China Hospital Sichuan UniversityChengdu 610041China China International Emergency Medical Team Chengdu 610041China Emergency Department West China HospitalSichuan UniversityChengdu 610041China West China School of Nursing Sichuan UniversityChengdu 610041China Department of Critical Care Medicine West China HospitalSichuan UniversityChengdu 610041China

BACKGROUND:The quick sequential organ failure assessment(qSOFA)is recommended to identify sepsis and predict sepsis ***,some studies have recently shown its poor performance in sepsis mortality *** enhance its effectiveness,researchers have developed various revised versions of the qSOFA by adding other parameters,such as the lactate-enhanced qSOFA(LqSOFA),the procalcitonin-enhanced qSOFA(PqSOFA),and the modified qSOFA(MqSOFA).This study aimed to compare the performance of these versions of the qSOFA in predicting sepsis mortality in the emergency department(ED).METHODS:This retrospective study analyzed data obtained from an electronic register system of adult patients with sepsis between January 1 and December 31,*** operating characteristic(ROC)curve analyses were performed to determine the area under the curve(AUC),with sensitivity,specificity,and positive and negative predictive values calculated for the various ***:Among the 936 enrolled cases,there were 835 survivors and 101 *** AUCs of the LqSOFA,MqSOFA,PqSOFA,and qSOFA were 0.740,0.731,0.712,and 0.705,*** sensitivity of the LqSOFA,MqSOFA,PqSOFA,and qSOFA were 64.36%,51.40%,71.29%,and 39.60%,*** specificity of the four scores were 70.78%,80.96%,61.68%,and 91.62%,*** LqSOFA and MqSOFA were superior to the qSOFA in predicting in-hospital ***:Among patients with sepsis in the ED,the performance of the PqSOFA was similar to that of the qSOFA and the values of the LqSOFA and MqSOFA in predicting in-hospital mortality were greater compared to *** the added parameter of the MqSOFA was more convenient compared to the LqSOFA,the MqSOFA could be used as a candidate for the revised qSOFA to increase the performance of the early prediction of sepsis mortality.

关键词： Quick sequential organ failure assessment In-hospital mortality Sepsis Lactate-enhanced qSOFA Modified qSOFA

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