Comparison of different versions of the quick sequential organ failure assessment for predicting in-hospital mortality of sepsis patients:A retrospective observational study

作     者：Hai Hu Jing-yuan Jiang Ni Yao Hai Hu;Jing-yuan Jiang;Ni Yao

作者机构：Emergency Office of West China HospitalSichuan UniversityChengdu 610041China China International Emergency Medical TeamChengdu 610041China Emergency DepartmentWest China HospitalSichuan UniversityChengdu 610041China West China School of NursingSichuan UniversityChengdu 610041China Department of Critical Care MedicineWest China HospitalSichuan UniversityChengdu 610041China 

出 版 物：《World Journal of Emergency Medicine》 (世界急诊医学杂志（英文）)

年 卷 期：2022年第13卷第2期

页      面：114-119页

核心收录：

学科分类：100218[医学-急诊医学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：Quick sequential organ failure assessment In-hospital mortality Sepsis Lactate-enhanced qSOFA Modified qSOFA 

摘      要：BACKGROUND:The quick sequential organ failure assessment(qSOFA)is recommended to identify sepsis and predict sepsis ***,some studies have recently shown its poor performance in sepsis mortality *** enhance its effectiveness,researchers have developed various revised versions of the qSOFA by adding other parameters,such as the lactate-enhanced qSOFA(LqSOFA),the procalcitonin-enhanced qSOFA(PqSOFA),and the modified qSOFA(MqSOFA).This study aimed to compare the performance of these versions of the qSOFA in predicting sepsis mortality in the emergency department(ED).METHODS:This retrospective study analyzed data obtained from an electronic register system of adult patients with sepsis between January 1 and December 31,*** operating characteristic(ROC)curve analyses were performed to determine the area under the curve(AUC),with sensitivity,specificity,and positive and negative predictive values calculated for the various ***:Among the 936 enrolled cases,there were 835 survivors and 101 *** AUCs of the LqSOFA,MqSOFA,PqSOFA,and qSOFA were 0.740,0.731,0.712,and 0.705,*** sensitivity of the LqSOFA,MqSOFA,PqSOFA,and qSOFA were 64.36%,51.40%,71.29%,and 39.60%,*** specificity of the four scores were 70.78%,80.96%,61.68%,and 91.62%,*** LqSOFA and MqSOFA were superior to the qSOFA in predicting in-hospital ***:Among patients with sepsis in the ED,the performance of the PqSOFA was similar to that of the qSOFA and the values of the LqSOFA and MqSOFA in predicting in-hospital mortality were greater compared to *** the added parameter of the MqSOFA was more convenient compared to the LqSOFA,the MqSOFA could be used as a candidate for the revised qSOFA to increase the performance of the early prediction of sepsis mortality.