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Analytical Solution for the Reissner-Sagoci Problem of a Piezoelectric half-Space

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Acta Mechanica Solida Sinica 2024年第3期37卷 363-370页

作者： Keqiang Hu Cun-fa Gao Zengtao Chen Zheng Zhong State Key Laboratory of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and AstronauticsNanjing210016China Department of Mechanical Engineering University of AlbertaEdmontonABT6G 1H9Canada School of Science Harbin Institute of TechnologyShenzhen518055China

In this paper,a transversely isotropic piezoelectric half-space with the isotropy axis parallel to the z-axis is considered under rotation on a rigid circular disk bonded to the surface of the piezoelectric *** is a type of Reissner-Sagoci mixed boundary value *** utilizing the hankel transform,the mixed boundary value problem is simplified into solving a pair of dual integral ***-field analytical expressions for displacement,stresses,and electric displacement inside the half-space are *** shear stresses and electric displacement on the surface are found to be singular at the edge of the rigid circular disk,and the stress intensity factors and electric displacement intensity factor are *** results show that material properties and geometric size have significant effects on displacement,shear stresses,and electric displacement.

关键词： Piezoelectric half-space Circular disk Reissner-Sagoci problem Stress intensity factor Electric displacement intensity factor

CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer

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Genes & Diseases 2024年第4期11卷 381-399页

作者： Ming Shao Qingfei Pan haiyan Tan Jing Wu ha Won Lee Andrew D.Huber William C.Wright Ji-Hoon Cho Jiyang Yu Junmin Peng Taosheng Chen Department of Chemical Biology and Therapeutics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Computational Biology St.Jude Children's Research HospitalMemphisTN 38105USA Center for Proteomics and Metabolomics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Structural Biology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Developmental Neurobiology St.Jude Children's Research HospitalMemphisTN 38105USA

CYP3A5 is a cytochrome P450(CYP)enzyme that metabolizes drugs and contributes to drug resistance in ***,it remains unclear whether CYP3A5 directly influences cancer *** this report,we demonstrate that CYP3A5 regulates glucose metabolism in pancreatic ductal ***-omics analysis showed that CYP3A5 knockdown re-sults in a decrease in various glucose-related metabolites through its effect on glucose trans-port.A mechanistic study revealed that CYP3A5 enriches the glucose transporter GLUT1 at the plasma membrane by restricting the translation of TXNIP,a negative regulator of ***,CYP3A5-generated reactive oxygen species were proved to be responsible for atten-uating the AKT-4EBP1-TXNIP signaling ***3A5 contributes to cell migration by maintaining high glucose uptake in pancreatic *** together,our results,for the first time,reveal a role of CYP3A5 in glucose metabolism in pancreatic ductal adenocarcinoma and identify a novel mechanism that is a potential therapeutic target.

关键词： Cell migration CYP3A5 Glucose metabolism GLUT1 Pancreatic cancer TXNIP

NUDT5 promotes the growth,metastasis,and Warburg effect of IDH wild-type glioblastoma multiforme cells by upregulating TRIM47

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 82-92页

作者： Zi-fa Zhang Shu-Ming Liu Neurosurgery Department Shanxi Bethune HospitalTaiyuanShanxi Province030022China Shanxi Academy of Medical Sciences TaiyuanShanxi province030022China Emergency Department Taiyuan People’s HospitalTaiyuanShanxi Province030021China

Objective:To explore the regulatory mechanism of NUDT5 in glioblastoma multiforme(GBM).Methods:GEPIA database was used to predict the expressions of NUDT5 and tripartite motif family proteins 47(TRIM47)in GBM ***-qPCR and Western blot analyses were performed to examine NUDT5 expression in GBM ***-229 cell proliferation,migration as well as invasion were estimated by CCK-8,colony formation,wound healing,and Transwell assays following interference with *** assay,L-lactic acid kit,glucose detection kit,and ATP detection kit were applied for the detection of glycolysis-related ***-immunoprecipitation experiment was carried out to verify the relationship between NUDT5 and ***:GEPIA database showed that NUDT5 expression was significantly increased in GBM *** the expression of NUDT5 in GBM cells significantly suppressed the viability,proliferation,invasion,migration,and glycolysis of GBM ***,TRIM47 was highly expressed in GBM cells and interacted with *** of TRIM47 partially reversed the inhibitory effect of NUDT5 downregulation on the proliferation,metastasis,and glycolysis of GBM ***:NUDT5 promotes the growth,metastasis,and Warburg effect of GBM cells by upregulating *** NUDT5 and TRIM47 can be used as targets for GMB treatment.

关键词： Glioblastoma multiforme NUDT5 TRIM47 Growth Metastasis Warburg effect

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乾隆朝清厘僧道停颁牒照档案(上)

历史档案 2024年第2期 4-20页

作者：无哈恩忠中国第一历史档案馆不详

度牒是官方颁发给出家僧道之合法身份证明。一般认为度牒始于北魏时期,唐代设立度牒制度,持有度牒的僧道可免除租税徭役、云游各处。清初依然沿袭度牒制度,康熙初年停止。乾隆帝登基后,为管理和控制僧道数量,予以恢复。由于度牒的特殊作... 详细信息

度牒是官方颁发给出家僧道之合法身份证明。一般认为度牒始于北魏时期,唐代设立度牒制度,持有度牒的僧道可免除租税徭役、云游各处。清初依然沿袭度牒制度,康熙初年停止。乾隆帝登基后,为管理和控制僧道数量,予以恢复。由于度牒的特殊作用,致遁入空门的僧道人数众多,“若辈不耕而食,不织而衣,且甘食美衣,公然以为分所应得”,其中鱼龙混杂,不免有“无赖游手”,甚至混入获罪逃匿者。加之度牒买卖转让,管理人员乘机借端需索,亦有害吏治。鉴于种种原因,乾隆三十九年(1774)六月颁布上谕:“所有礼部奏请给发牒照之处,着永远停止。”实行千年的度牒制度终被废除。档案中所称牒照亦指度牒。本组档案史料选编自中国第一历史档案馆藏内阁题本、宫中朱批奏折、军机处录副奏折及上谕档等,涉及乾隆中期以前清廷清厘僧道停颁度牒的系列内容,可供研究参考。

关键词：度牒录副奏折僧道身份证明乾隆朝北魏时期管理人员档案

Area Operators on Bergman Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1161-1176页

作者： Xiao Fen LV Jordi PAU Mao fa WANG Department of Mathematics Huzhou UniversityHuzhou 313000P.R.China Departament de Matemàtiques i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain School of Mathematics and Statistics Wuhan UniversityWuhan 430072P.R.China

We completely cha.a.terize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0 详细信息

We completely cha.a.terize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0ha.a.terizations for the area operators to be *** solve the cases left open there and extend the results to n-complex dimension.

关键词： Area operator Bergman space tent space area formula

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越南学生汉语动物成语习得偏误分析

越南学生汉语动物成语习得偏误分析

作者： TRUONG LE ha NHU 重庆交通大学

学位级别：硕士

汉语成语一直被认为是中华文化的精华,是汉语学习过程中不可忽视的一部分。现在学习汉语的越南人越来越多。对越南学生来说,仅会简单说一点汉语是不够的,他们希望了解更多成语,更深层次地了解汉语成语背后的文化,提高汉语运用能力。但... 详细信息

汉语成语一直被认为是中华文化的精华,是汉语学习过程中不可忽视的一部分。现在学习汉语的越南人越来越多。对越南学生来说,仅会简单说一点汉语是不够的,他们希望了解更多成语,更深层次地了解汉语成语背后的文化,提高汉语运用能力。但由于动物成语的丰富性、结构的稳定性、意义的整体性和语法功能的多样性以及汉语文化背景、风俗习惯的多元性,再加上两国的地理环境及国家的民族思维方式存在差异,两国人民对同一种动物的联想在认知和理解上也存在很多差异。这导致越南学生很难掌握动物成语知识,在应用成语中常常出现偏误。因此,笔者作为越南学生,为了帮助越南学生更深入地学习和理解汉语动物成语,拟研究越南学生在汉语动物成语习得过程中遇到的偏误,归纳偏误类型,分析偏误原因并提出针对性的学习策略。本研究通过深入分析汉语与越南语动物成语的构词特点和文化内涵差异,揭示了语言结构和文化背景理解不足是导致越南学生在学习汉语动物成语时产生偏误的主要原因。通过设计并实施调查问卷,详细分析了越南学生在汉语动物成语学习中的具体偏误类型,包括语义偏误、语法偏误和语用偏误。调查结果显示,这些偏误不仅影响了学生运用语言的准确性,也限制了他们对汉语文化深层次的理解。针对发现的问题,本文提出了相应的对策,旨在帮助越南学生克服学习障碍,深化对汉语动物成语及其背后文化的理解。这些对策包括加强文化背景知识学习、采用成语分类和归纳法,以及通过多样化的学习活动和资源创造丰富的学习环境。研究强调通过多媒体资源、实践互动和中越文化交流活动等手段,激发学生的学习兴趣,提高其汉语成语的实际应用能力。本研究对于汉语作为第二语言的教学实践具有重要意义。通过实施本研究提出的学习对策,不仅可以有效减少越南学生在汉语成语学习中的偏误,还可以促进中越文化的交流与理解,为越南学生提供一条深入学习汉语、提升跨文化交际能力的有效途径。

关键词：越南学生动物成语偏误分析学习策略

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中华民族共同体学话语体系的创新

中南民族大学学报（人文社会科学版） 2024年第9期44卷 41-43页

作者：哈正利大连民族大学

2023年12月,国家民族事务委员会组织编写的《中华民族共同体概论》(以下简称《概论》)教材正式出版。该教材以习近平总书记关于加强和改进民族工作的重要思想为根本遵循。总体看来,《概论》教材成功建构了一个新的中华民族共同体叙事体... 详细信息

2023年12月,国家民族事务委员会组织编写的《中华民族共同体概论》(以下简称《概论》)教材正式出版。该教材以习近平总书记关于加强和改进民族工作的重要思想为根本遵循。总体看来,《概论》教材成功建构了一个新的中华民族共同体叙事体系和话语体系。中华民族史的研究肇始于近代中国。近代以来,陆续出版过一些中华民族史整体叙事的著作。

关键词：中华民族史《概论》中华民族共同体话语体系根本遵循教材习近平总书记叙事

Non-surgical treatment of diabetic foot ulcers on the dorsum of the foot with polydeoxyribonucleotide injection:Two case reports

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World Journal of Clinical Cases 2024年第20期12卷 4446-4451页

作者： Yooseok ha Jeong-Hee Kim Jiyoung Kim Hyeokjae Kwon Department of Plastic and Reconstructive Surgery Chungnam National University HospitalDaejeon 35015South Korea College of Nursing Woosuk UniversityWanju-gun 55338South Korea

BACKGROUND Diabetic foot ulcers are caused by a variety of factors,including peripheral neuropathy,peripheral arterial disease,impaired wound healing mechanisms,and repetitive *** with diabetic foot ulcer on the dorsum of the foot are often treated ***,the right non-surgical therapy must be chosen if surgical choices are contraindicated or if the patient prefers conservative treatment over *** SUMMARY The purpose of this case report is to highlight the efficacy of polydeoxyribonucleotide(PDRN)injection as a non-surgical treatment option for diabetic foot ulcers on the dorsum of the foot,particularly in patients who choose against surgical *** case report presents two cases of diabetic foot ulcers located on the dorsum of the foot that were successfully treated with PDRN injection as a non-surgical *** If the patient declines surgery for diabetic ulcers with Wagner grade II or below,PDRN injection can be effective if necrotic tissue is removed and the wound bed kept clean.

关键词： Diabetic foot Wound healing Regenerative medicine Polydeoxyribonucleotides Case report

Virtual reality for preoperative patient education: Impact on satisfaction, usability, and burnout from the perspective of new nurses

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World Journal of Clinical Cases 2024年第28期12卷 6204-6216页

作者： Jiyoung Kim Donghyun Kim Sang-ha Oh Hyeokjae Kwon College of Nursing Woosuk UniversityWanju-gun 55338South Korea Department of Medical Science Chungnam National University College of MedicineDaejeon 35015South Korea Department of Plastic and Reconstructive Surgery Chungnam National University HospitalDaejeon 35015South Korea Department of Plastic and Reconstructive Surgery Chungnam National University College of MedicineDaejeon 35015South Korea

BACKGROUND Traditional paper-based preoperative patient education is a struggle for new nurses and requires extensive *** this situation,virtual reality technology can help the new *** its potential benefits,there are studies on patient satisfaction but there is limited information on the usability of virtual reality(VR)technology for new nurses in giving preoperative education to *** To investigate the impact on satisfaction,usability,and burnout of a system using VR technology in preoperative patient *** The study involved 20 nurses from the plastic surgery ward and 80 patients admitted between April and May *** nurse taught four patients:Two using traditional verbal education and two using virtual *** System Usability Scale,After-Scenario Questionnaire,and Maslach Burnout Inventory(MBI)were employed to evaluate the impact of these education *** The VR education groups showed a statistically higher satisfaction than the traditional verbal education *** the three subscales of the MBI,emotional exhaustion and personal accomplishment improved statistically *** was also better in terms of *** This study suggests VR enhances usability and reduces burnout in nurses,but further research is needed to assess its impact on depersonalization and objective measures like stress and heart rate.

关键词： Virtual reality Preoperative care Patient education Burnout Usability Satisfaction Prospective studies