检索结果-南通市图书馆

World Journal of Gastroenterology 2013年第8期19卷 1306-1313页

作者： Xiu-lan Peng Meng-Yao Ji Zi-Rong Yang Jia Song Wei-Guo Dong Department of Gastroenterology Renmin Hospital of Wuhan University

AIM:To determine the effect and molecular mechanism of ezrin-radixin-moesin-binding phosphoprotein-50(EBP50) in hepatocellular carcinoma(HCC).METHODS:Three human HCC cell lines,i.e.,SMMC7721,HepG2 and Hep3B,were *** transfected the Pbk-CMV-ha-EBP50 plasmid into SMMC7721 cells with Lipofectamine 2000 to overexpress *** blotting were performed to determine the effects of the plasmid on EBP50 expression and to detect the expression of β-catenin and E-cadherin before and after the transfection of the plasmid into SMMC7721 *** vitro cell proliferation was assessed with a Cell Counting Kit-8(CCK-8) *** cycle distribution was assessed with flow *** and migration ability of before and after the transfection were determined with a transwell *** apoptosis was demonstrated with Annexin *** effect of EBP50 overexpressing on tumor growth in vivo was performed with a xenograft tumor model in nude ***:The transfection efficiency was confirmed with Western blotting(1.36 ± 0.07 vs 0.81 ± 0.09,P hat the growth of cells overexpressing EBP50 was significantly lower than control cells(P hat cell invasion and migration were significantly inhibited in cells overexpressing EBP50 compared with control cells(5.8 ± 0.8 vs 21.6 ± 1.3,P hat apoptosis was significantly increased in cells overexpressing EBP50 compared with control cells(14.8% ± 2.7% vs 3.4% ± 1.3%,P hat up-regulation of EBP50 could obviously slow the growth of HCC derived from SMM

关键词： Hepatocellular carcinoma Ezrin-radixinmoesin-binding phosphoprotein-50 Growth Migration Invasion

Corrosion resistance of biodegradable polymeric layer-by-layer coatings on magnesium alloy AZ31

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2016年第2期10卷 134-146页

作者： lan-Yue CUI Rong-Chang ZENG Xiao-Xiao ZHU Ting-Ting PANG Shuo-Qi LI Fen ZhaNG College of Materials Science and Engineering Shandong University of Science and Technology Qingdao 266590 China State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology Shandong University of Science and Technology Qingdao 266590 China

Biocompatible polyelectrolyte multilayers （PEMs） and polysiloxane hybrid coatings were prepared to improve the corrosion resistance of biodegradable Mg alloy AZ31. The PEMs, which contained alternating poly（sodium 4-styrenesulfonate）（PSS） and poly（allylamine hydrochloride）（PAH）, were first self-assembled on the surface of the AZ31 alloy substrate via electrostatic interactions, designated as （PAH/PSS）s/AZ31. Then, the （PAH/PSS）5/AZ31 samples were dipped into a methyltrimethoxysilane （MTMS） solution to fabricate the PMTMS films, designated as PMTMS/（PAH/PSS）5/AZ31. The surface morphologies, microstructures and chemical compositions of the films were investigated by FE-SEM, FTIR, XRD and XPS. Potentiodynamic polarization, electro- chemical impedance spectroscopy and hydrogen evolution measurements demonstrated that the PMTMS/（PAH/PSS）s/AZ31 composite film significantly enhanced the corrosion resistance of the AZ31 alloy in hank＇s balanced salt solution （HBSS）. The PAH and PSS films effectively improved the deposition of Ca-P compounds including Ca3（PO4）2 and hydroxyapatite （ha）. Moreover, the corrosion mechanism of the composite coating was discussed. These coatings could be an alternative candidate coating for biodegradable Mg alloys.

关键词： magnesium alloy polyelectrolyte polysiloxane corrosion layer-by-layer

Carbon nanotubes-reinforced polylactic acid/hydroxyapatite porous scaffolds for bone tissue engineering

在线全文

学校读者我要写书评

暂无评论

Frontiers of Materials Science 2024年第1期18卷 59-69页

作者： Weiwei lan Mingbo Wang Zhenjun Lv Jun Li Fuying Chen Ziwei Liang Di Huang Xiaochun Wei Weiyi Chen Research Center for Nano-Biomaterials&Regenerative Medicine Department of Biomedical EngineeringCollege of Biomedical EngineeringTaiyuan University of TechnologyTaiyuan 030024China Guangdong Engineering Technology Research Center of Implantable Medical Polymer Shenzhen Lando Biomaterials Co.Ltd.Shenzhen 518107China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan 030060China Department of Orthopaedics The Second Hospital of Shanxi Medical UniversityTaiyuan 030001China

In the field of bone defect repair,critical requirements for favorable cytocompatibility and optimal mechanical properties have propelled research efforts towards the development of composite *** this study,carbon nanotubes/polylactic acid/hydroxyapatite(CNTs/PLA/ha)scaffolds with different contents(0.5,1,1.5 and 2 wt.%)of CNTs were prepared by the thermally induced phase separation(TIPS)*** results revealed that the composite scaffolds had uniform pores with high porosities over 68%and high through *** addition of CNTs significantly enhanced the mechanical properties of resulted PLA/ha,in which the 1.5 wt.%CNTs/PLA/ha composite scaffold demonstrated the optimum mechanical behaviors with the bending elastic modulus of(868.5±12.34)MPa,the tensile elastic modulus of(209.51±12.73)MPa,and the tensile strength of(3.26±0.61)***,L929 cells on the 1.5 wt.%CNTs/PLA/ha scaffold displayed good spreading performance and favorable ***,it is expected that the 1.5 wt.%CNTs/PLA/ha scaffold has potential applications in bone tissue engineering.

关键词： CNTs/PLA/ha scaffold TIPS method mechanical property bone tissue engineering

大黄中4个番泻苷类成分受热条件下转化关系的研究

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中成药 2012年第11期34卷 2169-2173页

作者：哈飞李瑞明张兰兰闫希军天津中医药大学天津300193 天津天士力集团研究院现代中药所天津300410

目的研究大黄中4个二蒽酮类成分番泻苷A、B、C、D在受热条件下的稳定性及相互转化关系。方法以大黄提取液和番泻苷A、B、C、D为研究对象,在80%乙醇中加热回流1 h的条件下,采用HPLC对各时刻的成分进行比较,考察稳定性及转化关系。结果大... 详细信息

目的研究大黄中4个二蒽酮类成分番泻苷A、B、C、D在受热条件下的稳定性及相互转化关系。方法以大黄提取液和番泻苷A、B、C、D为研究对象,在80%乙醇中加热回流1 h的条件下,采用HPLC对各时刻的成分进行比较,考察稳定性及转化关系。结果大黄中4个番泻苷类成分在受热1 h条件下均存在降解,番泻苷A和番泻苷B在80%乙醇中加热回流1 h的条件下,可以互相转化且都有番泻苷C生成。番泻苷C和番泻苷D在80%乙醇中加热回流1 h的条件下,可以相互转化且都有番泻苷B和新的中间产物生成。结论揭示了大黄在回流加热过程中番泻苷类成分的转化途径,为大黄在今后的中药制剂和临床应用中提供了数据支持。

关键词：大黄番泻苷加热回流转化关系

Immobilization of pegylated AMP on hydroxyapatite nanorods for antibiosis

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2022年第2期41卷 713-722页

作者： Huan-Ming Chen hao-Yu Huang Yang Xue Kai Li Tie-Xin Ding Xiao-Jun Cai Jun Chen lan Zhang School of Material Science and Engineering Nanjing Technology UniversityNanjing 211816China State-Key Laboratory for Mechanical Behavior of Materials Xi'an Jiaotong UniversityXi'an 710049China Department of Osteology Xi’an People’s Hospital(Xi’an No.4 Hospital)Xi'an 710100China Department of Osteology Tangdu HospitalFourth Military Medical UniversityXi’an 710038China

Infection is one of the major reasons whichinduce failure of percutaneous Ti *** bonding of antimicrobial peptides(AMPs)on Ti surfaces can avoid AMPs'blast release by physical absorption,but the reduced mobility affects their antibacterial *** this paper,HHC36 was pegylated with PEG12 and immobilized on hydroxyapatite(ha)nanorods to endow Ti surface with antibacterial activity and improved cytocom-patibility *** obtained results indicated that ha nanorods immobilized with HHC36 showed antibacterial activity,and pegylation obviously increased the antibacterial activity of immobilized HHC36 against staphylococcus *** reached 99.5%and 97.0%in vitro and in vivo,***12 is flexible,and it increases mobility of HHC36 and enables lateral diffusion of peptide molecules into the lipid double layer of microbial membrane,resulting in highly antibacterial activity of ***,ha nanorods immobilized with pegylated HHC36 have reduced inflammatory response in an infection model and should be potentially applied on percutaneous Ti implants for reducing infection-induced failure and enhancing biointegration.

关键词： Percutaneous implant Hydroxyapatite(ha)nanorods Antimicrobial peptide Spacer Antibiosis

Assessment of Radiation Dose Caused by Radioactive Gaseous Effluent Released from Nuclear Power Plant Ninh Thuan 1 under Scenario of Normal Working Conditions

在线全文

学校读者我要写书评

暂无评论

World Journal of Nuclear Science and Technology 2015年第3期5卷 183-191页

作者： Nguyen Tuan Khai Do Xuan anh Le Dinh Cuong Duong Duc Thang Vuong Thu Bac Nguyen Thi Thu ha Nguyen Quang Long Trinh Van Giap Nguyen hao Quang Institute for Nuclear Science and Technology (INST) Hanoi Vietnam Vietnam Atomic Energy Institute (VINATOM) Hanoi Vietnam

Based on guides RG 1.109, RG 1.111 published by United States Nuclear Regulatory Commission (USNRC), our research concentrates in assessing radiation doses caused by radioactive substances released from the nuclear power plant (NPP) Ninh Thuan 1 under the scenario of normal operation using software package NRCDose72 provided by the USNRC. The database including the released radioactive nuclides, meteorology, terrain, population and agricultural production activities have been collected and processed to build the input data for the model calculation. The wind rose distribution obtained from the meteorological data in a five-year period from 2009-2013 showed that the radioactive nuclides released to environment spread in two main wind directions which are North East and South West. The X/Q (s/m3) and D/Q (s/m2) qualities which are, respectively, the ratio of activity concentration to release rate and that of deposition density of radioactive nuclides to release rate were calculated within an area of 80 km radius from the NPP site using XOQDOQ. Population doses were calculated using GASPAR. The XOQDOQ and GASPAR are two specific softwares in NRCDose72 package.

关键词： NPP Radioactive Release Radiation Dose Population Dose X/Q and D/Q

Studies on the Combination of Some Selected Microorganisms for Biodegradation of Cassava Peel Wastes （Manihot Esculenta）

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Science and Engineering(B) 2016年第7期5卷 342-347页

作者： Thanh Tran Vo Duy Minh Do Vu Thanh Son Le Thi anh Hong Hong N-hung Do Nguyen Dinh Duc Nguyen Thi Bach Huyen Nguyen Thi Van ha NTT Hi-Tech Institute Nguyen Tat Thanh University HCM City 700000 Vietnam Faculty of Environment Ho Chi Minh City University of Natural Resources and Environment HCM City 700000 Vietnam Institute of Tropical Biology Vietnam Academy of Science and Technology HCM City 700000 Vietnam

Cassava peel has a lot of nutrients which can be utilized as fertilizer in agriculture. However, high cellulose contents may cause difficulty for organic digestion and slow down the nutrient absorption for plants. This study aims to reach the microorganisms or their combination for biodegradating the cassava peel waste. The initial result shows that after 21 days the glucose concentration in all samples was the highest during experiment times. The reducing glucose produced in mg/mL by the selected bacteria was 9.32, higher than the selected fungie of 1.57 mg/mL. The percentage degradation of cassava peel weigh was the highest for fungi which was 52% of weigh, respectively. Meanwhile, bacteria only degradated about 31.6% after 4 weeks. However, the combination between bacteria and fungi provides the highest glucose concentration, 19.29 mg/mL and digests 62% of the mass cassava in experiment. This study suggests that biodegradation of agro-wastes in the environment to reduce biomass waste pollution is very promising.

关键词： Biodegradation bacteria cassava peel wastes fungi.

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

红外热像技术在电气设备故障检测中的应用

安全 2007年第12期28卷 13-15页

作者：哈兰首都经济贸易大学

红外热像技术是红外检测技术的一种,可以用来发现所有运行的电气设备的热隐患,能有效地防止电气事故、火灾的发生。本文主要阐述红外热像技术的原理、分类、检测方法和检测原理、局限性和不足以及在电气设备故障检测中的应用,并以实例... 详细信息

红外热像技术是红外检测技术的一种,可以用来发现所有运行的电气设备的热隐患,能有效地防止电气事故、火灾的发生。本文主要阐述红外热像技术的原理、分类、检测方法和检测原理、局限性和不足以及在电气设备故障检测中的应用,并以实例加以描述。

关键词：红外检测红外热像仪电气设备故障检测

FER Performance in the IEEE 802.11 a/g/n Wireless lan over Fading Channel

在线全文

学校读者我要写书评

暂无评论

Communications and Network 2013年第3期5卷 10-15页

作者： ha Cheol Lee Dept. of Information and Comm. Eng. Yuhan University Bucheon City Korea

This paper explores and compares FER (Frame Error Rate) of a MAC (Medium Access Control) layer in the IEEE 802.11 a/g/n wireless lan. It is evaluated under the fading wireless channel, using theoretical analysis method. It is analyzed by using the number of stations with both variable payload size and mobile speed on the condition that fading margin and transmission probability are fixed. Especially, in the IEEE 802.11n, A-MSDU (MAC Service Data Unit Aggregation) scheme is considered and the number of subframe is used as the variable parameter. In the IEEE802.11a/g wireless lan, fixed wireless channel is assumed to be Rayleigh fading channel. Mobile wireless channel is assumed to be flat fading Rayleigh channel with Jake spectrum. The channel is in fading states or inter-fading states by evaluating a certain threshold value of received signal power level. If and only if the whole frame is in inter-fading state, there is the successful frame transmission. If any part of frame is in fading duration, the frame is received in error.

关键词： Wireless lan MAC FER IEEE 802.11a/g/n

The Serum Level of CD16 + 56 in Zona

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cosmetics, Dermatological Sciences and Applications 2021年第1期11卷 1-9页

作者： Nguyễn lan anh Bùi Thị Vân Vũ Thu Trang Đặng Trung Thành Nguyễn Thị Quỳnh Trang Nguyễn Thị Tuấn Đặng Văn Em Department of Dermatology Venereology Allergy 108 Military Central Hospital Ha Noi Vietnam Department of Immunology 108 Military Central Hospital Ha Noi Vietnam

Objectives: To study the change of CD16 + 56 in zona. Materials and Methods: 62 zona patients admitted at Inpatient Department of Dermatology, Venereology Allergy, 108 Military Central Hospital, and 30 healthy volunteers who were matched for age and sex participated in this study. Prospective, cross-sectional study with controls was conducted. We measured the number of CD16 + CD56 by flow cytometry using FACS Callibur. Results: The mean level of CD16 + 56 in zona patients was 253 ± 200 (106 cells/l), which was lower than that of control group but then increased after treatment. The change of CD16 + 56 did not correlate with patients’ age. Patients who were in severe condition or had affected size from 3% or more had a lower number of CD16 + 56 than control group. Conclusion: The number of CD16 + 56 in zona patients were lower than that of healthy people.

关键词： CD16 + 56 Zona