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Fluid identification and tight oil layer classification for the southwestern Mahu Sag,Junggar Basin using NMR logging-based spectrum decomposition

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Energy Geoscience 2024年第2期5卷 62-69页

作者： Wenbiao huang Yibing Guo Jun qin Zhongchen Ba Zongbin Zhang Luning Bai Heng Li School of Geosciences China University of Petroleum(East China)QingdaoShandong266580China PetroChina Xinjiang Oilfield Company KaramayXinjiang834000China

The intricate distribution of oil and water in tight rocks makes pinpointing oil layers *** conventional identification methods offer potential solutions,their limited accuracy precludes them from being effective in their applications to unconventional *** study employed nuclear magnetic resonance(NMR)spectrum decomposition to dissect the NMR T_(2)spectrum into multiple ***,it employed laboratory NMR experiments to ascertain the fluid properties of these sub-spectra,aiming to enhance identification *** findings indicate that fluids of distinct properties overlap in the T_(2)spectra,with bound water,movable water,bound oil,and movable oil appearing sequentially from the low-value zone to the high-value ***,an oil layer classification scheme was proposed,which considers the physical properties of reservoirs,oil-bearing capacity,and the characteristics of both mobility and the oil-water two-phase *** applied to tight oil layer identification,the scheme's outcomes align closely with actual test results.A horizontal well,deployed based on these findings,has produced high-yield industrial oil flow,underscoring the precision and dependability of this new approach.

关键词： Nuclear magnetic resonance Fluid identification Oil layer identification NMR T_(2)spectrum decomposition Normal distribution simulation

The ABA synthesis enzyme allele OsNCED2^(T)promotes dryland adaptation in upland rice

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The Crop Journal 2024年第1期12卷 68-78页

作者： Liyu huang Yachong Bao Shiwen qin Min Ning qinyan Li qingmao Li Shilai Zhang Guangfu huang Jing Zhang Wensheng Wang Binying Fu Fengyi Hu key Laboratory of Biology and Germplasm Innovation of Perennial Rice from Ministry of Agriculture and Rural Affairs School of AgricultureYunnan UniversityKunming 650091YunnanChina National key Facility for Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijing 100081China

Upland rice shows dryland adaptation in the form of a deeper and denser root system and greater drought resistance than its counterpart,irrigated *** previous study revealed a difference in the frequency of the OsNCED2 gene between upland and irrigated populations.A nonsynonymous mutation(C to T,from irrigated to upland rice)may have led to functional variation fixed by artificial selection,but the exact biological function in dryland adaptation is *** this study,transgenic and association analysis indicated that the domesticated fixed mutation caused functional variation in OsNCED2,increasing ABA levels,root development,and drought tolerance in upland rice under dryland ***2-overexpressing rice showed increased reactive oxygen species-scavenging abilities and transcription levels of many genes functioning in stress response and development that may regulate root development and drought ***2^(T)-NILs showed a denser root system and drought resistance,promoting the yield of rice under dryland ***2^(T)may confer dryland adaptation in upland rice and may find use in breeding dryland-adapted,water-saving rice.

关键词： Upland rice Dryland adaptation ABA Root development Drought tolerance

A drug-loaded flexible substrate improves the performance of conformal cortical electrodes

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Bio-Design and Manufacturing 2024年第4期7卷 399-412页

作者： Rongrong qin Tian Li Yifu Tan Fanqi Sun Yuhao Zhou Ronghao Lv Xiaoli You Bowen Ji Peng Li Wei huang Frontiers Science Center for Flexible Electronics(FSCFE) Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&Engineering(IBME)Northwestern Polytechnical UniversityXi’an 710072China Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China Ministry of Education key Laboratory of Micro and Nano Systems for Aerospace School of Mechanical EngineeringNorthwestern Polytechnical UniversityXi’an 710072China key Laboratory of Flexible Electronics of Zhejiang Province Ningbo Institute of Northwestern Polytechnical UniversityNingbo 315103China

Cortical electrodes are a powerful tool for the stimulation and/or recording of electrical activity in the nervous ***,the inevitable wound caused by surgical implantation of electrodes presents bacterial infection and inflammatory reaction risks associated with foreign body ***,inflammation of the wound area can dramatically worsen in response to bacterial *** consequences can not only lead to the failure of cortical electrode implantation but also threaten the lives of ***,we prepared a hydrogel made of bacterial cellulose(BC),a flexible substrate for cortical electrodes,and further loaded antibiotic tetracycline(TC)and the anti-inflammatory drug dexamethasone(DEX)onto *** encapsulated drugs can be released from the BC hydrogel and effectively inhibit the growth of Gram-negative and Gram-positive ***,therapeutic cortical electrodes were developed by integrating the drug-loaded BC hydrogel and nine-channel serpentine arrays;these were used to record electrocorticography(ECoG)signals in a rat *** to the controlled release of TC and DEX from the BC hydrogel substrate,therapeutic cortical electrodes can alleviate or prevent symptoms associated with the bacterial infection and inflammation of brain *** approach facilitates the development of drug delivery electrodes for resolving complications caused by implantable electrodes.

关键词： Antibacterial Anti-inflammatory Drug loading Cortical electrodes Bacterial cellulose hydrogel

Efficacy and safety of Yangxue qingnao Granules in treatment of migraine:A systematic review and meta-analysis

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World Journal of Clinical Cases 2024年第2期12卷 335-345页

作者： Bo Zhou Gui-Shu Wang Yu-Ning Yao Tong Hao Huan-qin Li ke-Gang Cao Department of Neurology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing 100091China Department of Infectious Disease Dongfang HospitalBeijing University of Chinese MedicineBeijing 100078China Institute for Brain Disorders Beijing University of Chinese MedicineBeijing 100700China Department of Acupuncture and Moxibustion Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical UniversityBeijing 100010China

BACKGROUND Yangxue qingnao Granules(YXQN)is a Chinese patent medicine that has been commonly used in the clinical treatment of *** To assess the efficacy and safety of YXQN alone for the treatment of *** We searched 10 databases to identify relevant randomized controlled trials(RCTs)published before September *** review authors independently searched and screened the literature,extracted the data,and assessed the methodological quality of the studies using criteria from ROB 2.0,and analyzed the data using Review Manager 5.4 *** A total of 12 RCTs including 767 participants with migraine met the selection *** divided these studies into comparisons of YXQN with placebo,routine treatment drugs,and other Chinese patent *** meta-analysis showed the following:(1)Efficacy:The YXQN group outperformed the placebo group[relative risk(RR)=0.29,95%confidence interval(95%CI):0.15–0.43,P<0.00001],routine treatment group(RR=0.18,95%CI:0.09–0.27,P<0.0001),and Chinese patent medicine group(RR=0.27,95%CI:0.13–0.41,P<0.001);(2)frequency of headache:There was a significant difference between YXQN vs placebo[mean difference(MD)=-1.25,95%CI:-1.60 to-0.90,P<0.00001],routine treatment drugs(MD=-0.85,95%CI:-1.15 to-0.56,P<0.00001),and Chinese patent medicine(MD=-0.91,95%CI:-1.35 to-0.46,P<0.0001);(3)headache duration:We found great heterogeneity between studies,with no differences between YXQN and placebo(MD=-0.61,95%CI:-1.53 to-0.31,P=0.19)and routine treatment drugs(MD=-0.22,95%CI:-0.89 to 0.46,P<0.53).YXQN was more effective than other Chinese patent medicines in reducing headache duration(MD=-1.24,95%CI:-1.70 to-0.77,P<0.00001);and(4)headache severity:There was no significant difference between YXQN vs placebo(MD=-1.67,95%CI:-3.52 to 0.19,P=0.08),routine treatment drugs(MD=-0.53,95%CI:-2.02 to 0.96,P=0.68),and other Chinese patent medicines(MD=-0.49,95%CI:-2.83 to 1.85,P=0.68).Mild gastrointestinal adverse reactions were reported

关键词： Meta-analysis Migraine Yangxue qingnao Granules Traditional Chinese patent medicine

Making waste profitable: Efficient recovery of metallic iron from jarosite residues

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Chinese Journal of Chemical Engineering 2024年第7期71卷 66-76页

作者： Songshan Zhou Yunhui Han Rong huang Yin huang qingyuan Dong Haiyin Gang Jinchuan qin Xi Yu Xiangfei Zeng Wenxing Cao Jiqin Wang Shaoqin Chen Rong Wang Mengjun Chen key Laboratory of Solid Waste Treatment and Resource Recycle(SWUST) Ministry of EducationSouthwest University of Science and TechnologyMianyang 621010China School of Environment Key Laboratory of Yellow River and Huai River Water Environment and Pollution ControlMinistry of EducationHenan Normal UniversityXinxiang 453007China School of National Defense Science and Technology College SWUST Ministry of EducationSouthwest University of Science and TechnologyMianyang 621010China

To address the hazardous by-product of zinc smelting and resource utilization of jarosite residue,this study applies an electric field-assisted hot acid treatment to completely recycle iron(Fe).This innovative approach aims to enhance the leaching efficiency of Fe from jarosite *** introduction of an electric field changes the charge distribution on the surface of the particles to enhance ions and electrons exchange and promotes the collision between particles to strengthen reaction *** on the above,the leaching efficiency of Fe in jarosite under sulfuric acid attack has improved *** result shows that Fe leaching efficiency reaches 98.83%,which is increased by 28%under the optimal experimental conditions:current density of 30 mA·cm^(-2),H_(2)SO_(4) concentration of 1.5 mol·L^(-1),solid-liquid ratio of 70 g·L^(-1),temperature of 80℃ and time of 12 *** kinetics calculations show that the apparent activation energy is 16.97 kJ·mol^(-1) and the leaching of jarosite residue is controlled by a mixture of chemical reaction and diffusion,as well as the temperature and concentration of the leaching solution have an influence on *** work provides a feasible idea for the efficient leaching of Fe from jarosite residue.

关键词： Jarosite residue Electric filed Leaching kinetics

In Situ Deposition of Drug and Gene Nanoparticles on a Patterned Supramolecular Hydrogel to Construct a Directionally Osteochondral Plug

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Nano-Micro Letters 2024年第1期16卷 341-359页

作者： Jiawei Kang Yaping Li Yating qin Zhongming huang Yifan Wu Long Sun Cong Wang Wei Wang Gang Feng Yiying Qi Department of Orthopaedic Surgery The Second Affiliated HospitalZhejiang University School of MedicineHangzhou City 310009Zhejiang ProvincePeople’s Republic of China College of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310027People’s Republic of China ZJU-Hangzhou Global Scientific and Technological Innovation Center Hangzhou 311215ZhejiangPeople’s Republic of China The Affiliated Nanhua Hospital Orthopedic Research CentreHengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanPeople’s Republic of China Department of Radiology Jining No.1 People’s HospitalJining Medical UniversityJining 272000ShandongPeople’s Republic of China

The integrated repair of bone and cartilage boasts advantages for osteochondral restoration such as a long-term repair effect and less deterioration compared to repairing cartilage *** multifactorial,spatially oriented scaffolds to stimulate osteochondral regeneration,has immense ***,targeted drugs,namely kartogenin@polydopamine(KGN@PDA)nanoparticles for cartilage repair and miRNA@calcium phosphate(miRNA@CaP)NPs for bone regeneration,were in situ deposited on a patterned supramolecular-assembled 2-ureido-4[lH]-pyrimidinone(UPy)modified gelation hydrogel film,facilitated by the dynamic and responsive coordination and complexation of metal ions and their *** hydrogel film can be rolled into a cylindrical plug,mimicking the Haversian canal structure of natural *** resultant hydrogel demonstrates stable mechanical properties,a self-healing ability,a high capability for reactive oxygen species capture,and controlled release of KGN and *** vitro,KGN@PDA and miRNA@CaP promote chondrogenic and osteogenic differentiation of mesenchymal stem cells via the JNK/RUNX1 and GSK-3β/β-catenin pathways,*** vivo,the osteochondral plug exhibits optimal subchondral bone and cartilage regeneration,evidenced by a significant increase in glycosaminoglycan and collagen accumulation in specific zones,along with the successful integration of neocartilage with subchondral *** biomaterial delivery approach represents a significant toward improved osteochondral repair.

关键词： Osteochondral regeneration Oriented hydrogel Kartogenin miRNA-26a

Integrated multi-omics analysis reveals liver metabolic reprogramming by fish iridovirus and antiviral function of alpha-linolenic acid

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Zoological Research 2024年第3期45卷 520-534页

作者： Lin Liu Ya Zhang Meng-Di Yuan Dong-Miao Xiao Wei-Hua Xu Qi Zheng Qi-Wei qin You-Hua huang Xiao-Hong huang College of Marine Sciences South China Agricultural UniversityGuangdong Laboratory for Lingnan Modern AgricultureGuangzhouGuangdong 510642China Nansha-South China Agricultural University Fishery Research Institute GuangzhouGuangdong 511464China Southern Marine Science and Engineering Guangdong Laboratory ZhuhaiGuangdong 519082China

Iridovirus poses a substantial threat to global aquaculture due to its high mortality rate;however,the molecular mechanisms underpinning its pathogenesis are not well ***,a multi-omics approach was applied to groupers infected with Singapore grouper iridovirus(SGIV),focusing on the roles of key *** showed that SGIV induced obvious histopathological damage and changes in metabolic enzymes within the ***,SGIV significantly reduced the contents of lipid droplets,triglycerides,cholesterol,and *** analysis indicated that the altered metabolites were enriched in 19 pathways,with a notable down-regulation of lipid metabolites such as glycerophosphates and alpha-linolenic acid(ALA),consistent with disturbed lipid homeostasis in the *** of transcriptomic and metabolomic data revealed that the top enriched pathways were related to cell growth and death and nucleotide,carbohydrate,amino acid,and lipid metabolism,supporting the conclusion that SGIV infection induced liver metabolic *** integrative transcriptomic and proteomic analysis indicated that SGIV infection activated crucial molecular events in a phagosome-immune depression-metabolism dysregulation-necrosis signaling *** note,integrative multi-omics analysis demonstrated the consumption of ALA and linoleic acid(LA)metabolites,and the accumulation of L-glutamic acid(GA),accompanied by alterations in immune,inflammation,and cell death-related *** experimental data showed that ALA,but not GA,suppressed SGIV replication by activating antioxidant and anti-inflammatory responses in the ***,these findings provide a comprehensive resource for understanding host response dynamics during fish iridovirus infection and highlight the antiviral potential of ALA in the prevention and treatment of iridoviral diseases.

关键词： Iridovirus Liver damage Metabolic reprogramming SGIV Alpha-linolenic acid Antiinflammatory

Pollutant emissions from biomass burning:A review on emission characteristics,environmental impacts,and research perspectives

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Particuology 2024年第2期85卷 296-309页

作者： ke Jiang Ran Xing Zhihan Luo Wenxuan huang Fan Yi Yatai Men Nan Zhao Zhaofeng Chang jinfeng Zhao Bo Pan Guofeng shen College of Urban and Environmental Sciences Peking UniversityBeijing100871China Beijing key Lab Plant Resources Research and Development Beijing Technology and Business UniversityBeijing100048China College of Ecology and Environment Zhengzhou UniversityZhengzhou450001China Facultyof Environmental Sciences and Engineering Kunming University of Science and TechnologyYunnan Provincial Key Laboratoryof Soil Carbon Sequestration and Pollution ControlKunming650500China Institute of Carbon Neutrality Peking UniversityBeijing100871China

Biomass is one most abundant resource on the earth providing important energies in support of so-cioeconomic development in many *** of biomass fuels comprises to nearly 10%of the total energy from anthropogenic combustion processes:however,as the burning is usually incomplete,this process yields products of incomplete combustion posing consequently significant impacts on air quality,human health,and climate ***,we analyzed spatiotemporal characteristics in intentional and unintentional biomass burning from different sectors,discussed impacts of biomass burning emissions on indoor and outdoor air quality,and consequent influences on human *** global total con-sumption amount of biomass including both natural and anthropogenic sources was approximately 7900 Tg in 2019,with significantly large regional and sectorial discrepancies among ***,anthropogenic biomass burning amounts increased gradually,but notably in some developing countries like China residential consumption of biomass fuels,as one large sector of biomass use,decreased over *** biomass consumption needs to be accurately *** are relatively rich datasets of pollutant emission factors from biomass burning,including laboratory and field tests,but still large variations exit and contribute substantially to the uncertainty in emission *** pri-mary PM2.5,black carbon and organic carbon emissions from biomass burning were about 51,4.6,and 29 Tg,respectively,contributing to nearly 70%,55%,and 90%of the total emission from all sources,and emissions from the residential sector and open fires are major *** carbon emissions from biomass burning attracts growing interests but available studies adopted different methodologies challenging the comparability of those *** burning emissions polluted not only ambient air but more severely indoor air quality,adversely affecting human *** studies that should be emphasiz

关键词： Biomass burning Carbonaceous aerosol Emission Air quality Human health

Challenges and Prospects of Molecular Spintronics

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Precision Chemistry 2024年第1期2卷 1-13页

作者： Xianrong Gu Lidan Guo Yang qin Tingting Yang ke Meng Shunhua Hu Xiangnan Sun key Laboratory of Nanosystem and Hierarchical Fabrication National Center for Nanoscience and TechnologyBeijing 100190P.R.China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049P.R.China

Molecular spintronics,as an emerging field that makes full use of the advantage of ultralong room-temperature spin lifetime and abundant electrical-optical-magnetic properties of molecular semiconductors,has gained wide attention for its great potential for further commercial *** the significant progress that has been made,there remain several huge challenges that limit the future development of this *** Perspective provides discussions on the spin transport mechanisms and performances of molecular semiconductors,spinterface effect,and related spin injection in spintronic devices,and current spin-charge interactive functionalities,along with the summarization of the main obstacles of these ***,we particularly propose targeted solutions,aiming to enhance the spin injection and transport efficiency by molecular design and interface engineering and explore diverse spinrelated *** this Perspective,we hope it will help the spintronic community identify the research trends and accelerate the development of molecular spintronics.

关键词： Molecular spintronics spin transport spintronic materials spin injection spinterface effect spin-related functionality