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Journal of the Operations Research Society of China 2024年第2期12卷 495-504页

作者： Hong-Ye Zheng Suo-Gang Gao Wen Liu bo hou School of Mathematical Sciences Hebei Normal UniversityShijiazhuang 050024HebeiChina

In this paper,we consider the parallel-machine customer order scheduling with delivery time and submodular rejection *** this problem,we are given m dedicated machines in parallel and n customer *** order has a delivery time and consists of m product types and each product type should be manufactured on a dedicated *** order is either rejected,in which case a rejection penalty has to be paid,or accepted and manufactured on the m dedicated *** objective is to find a solution to minimize the sum of the maximum delivery completion time of the accepted orders and the penalty of the rejected orders which is determined by a submodular *** design an LP rounding algorithm with approximation ratio of n+1 for this problem.

关键词： Order scheduling Delivery time Submodular rejection penalty Approximation algorithm

Teaching Status and Teaching Reform Ideas of Physical Chemistry Experiments for Food Quality and Safety Major

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Agricultural Biotechnology 2024年第3期13卷 45-47,54页

作者： bo hou Jing LIAO College of Food and Bioengineering Chengdu UniversityChengdu 610106China Meat Processing Key Lab of Sichuan Province Chengdu UniversityChengdu 610106China

Physical chemistry experiments are an important branch of chemical *** view of problems and shortcomings in physical chemistry experiment teaching of food quality and safety major in Chengdu University,the teaching methods of physical chemistry experiment course of food quality and safety major were explored and practiced,aiming to arouse students enthusiasm for experiments and cultivate their ability of independent learning,comprehensive thinking and independent problem solving.

关键词： Physical chemistry experiment Food quality Safety

Dcalycinumines A-E,Alkaloids with Cytotoxic Activities of Nasopharyngeal Carcinoma Cells from Daphniphyllum calycinum

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Chinese Journal of Chemistry 2024年第1期42卷 35-42页

作者： Qing Tang Xiao-Yong Dai Qiang Lin Zhi-Peng Ling Yi-Kun Hao Tian-Xi Zhu Ji-Hui Zhang Yi-bo hou Yao-Lan Li Lai-Qiang Huang Jing-Hao Wang Guo-Cai Wang Yu-bo Zhang Guangdong Clinical Translational Centerfor Targeted Drug Department of PharmacologySchoolof MedicineJinan University GuangzhouGuangdong 510632China Institute of Traditional Chinese Medicine&Natural Products Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs ResearchCollegeof PharmacyJinan UniversityGuangzhouGuangdong511443China Institute of Biopharmaceutical and Health Engineering Shenzhen Key Laboratory of Gene and Antibody TherapyState Key Laboratory of Chemical OncogenomicsShenzhen International Graduate SchoolTsinghua UniversityShenzhenGuangdong 518055China The Guangzhou Key Laboratoryof Basic and Translational Research on Chronic Disease Department of PharmacyThe First Affiliated HospitalJinan UniversityGuangzhouGuangdong 510630China

Fivenovel Daphniphyllum alkaloids,named dcalycinumines A-E(1-4,6),andeight previously described Daphniphyllum alkaloids(5,7-13)were isolated from Daphniphyllum *** 1 is the first Daphniphyllum alkaloid possessing a highly rearranged 6/6/6/7/5/6 hexacyclic architecture with a unique 3-methyl-1-azabicyclo[4,4,0]decane ring *** 2 represents a rare diamino Daphniphyllum alkaloid with an unprecedented 6/5/5/6/6/5 carbon skeleton featuring a unique 1-aza-6-azaspiro[4,5]decane unit,whereas 3 also represents a rare diamino Daphniphyllum alkaloid as a possible precursor of *** 4 is the second example of c-22-nor yuzurimine-type *** structures and absolute configurations were elucidated by HRESIMS,NMR spectroscopic analyses,EcD calculations,and single-crystal X-ray ***,compound 1 showed remarkable antitumor activities,which could inhibit the proliferation,migration and invasion of nasopharyngeal carcinoma cells,and promoted nasopharyngeal carcinoma cells apoptosis.

关键词： Daphniphyllum calycinum Natural products Daphniphyllum alkaloid Structural elucidation Biological activity Apoptosis Nasopharyngealcarcinoma

以大历史观为指导科学总结新中国75年历史经验

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思想理论教育导刊 2024年第3期 96-103页

作者：侯波中国社会科学院大学政府管理学院

今年是中华人民共和国成立75周年。75年前的中华人民共和国成立,从根本上改变了中国人民和中华民族的前途命运,也深刻影响着世界历史的前进方向。站在新的历史起点上,全面客观、科学系统总结75年新中国史的奋斗成就和历史经验,特别是把... 详细信息

今年是中华人民共和国成立75周年。75年前的中华人民共和国成立,从根本上改变了中国人民和中华民族的前途命运,也深刻影响着世界历史的前进方向。站在新的历史起点上,全面客观、科学系统总结75年新中国史的奋斗成就和历史经验,特别是把中国特色社会主义进入新时代以来的治国理政新鲜经验放在新中国75年历史的长河中进行贯通总结,更有助于我们从新中国发展史中看清楚过去为什么能够成功,弄明白在强国建设、民族复兴的新征程上怎样才能继续成功,使全体中国人民更加坚定地以最大的政治清醒沿着中国式现代化道路笃定前行。

关键词：大历史观新中国成立75年历史经验

Study on Effects of Curing Process on Characteristics of Marinated Beef Products

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Agricultural Biotechnology 2024年第3期13卷 64-68,74页

作者： bo hou Jiamin ZHANG Wei WANG Ting BAI Lili JI College of Food and Bioengineering Chengdu UniversityChengdu 610106China Meat Processing Key Lab of Sichuan Province Chengdu UniversityChengdu 610106China

[Objectives]This study was conducted to compare the effects of different curing processes on the characteristics of marinated beef.[Methods]Marinated beef was obtained by two curing processes:static curing and injection and vacuum tumbling *** effects of the two curing processes on the production rate,curing absorption rate,water content,soluble protein content,amino acid nitrogen content,texture characteristics and microstructure of the product were compared.[Results]Compared with static curing,the production rate of marinated beef increased by 10%,the curing absorption rate increased by 28%,the texture and microstructure were improved,and the water content increased,while the soluble protein content *** a result,the sensory score was *** was no significant difference in the content of amino acid nitrogen,but it decreased compared with raw *** sum up,injection and vacuum tumbling curing is more conducive to the processing of marinated beef.[Conclusions]This study provides a theoretical basis for the industrial production of marinated beef,and lays a foundation for in-depth exploration of injection and vacuum tumbling curing technique of marinated beef.

关键词： Marinated beef Curing process Microstructure Texture Brine injection

食品安全风险治理中的公众参与意愿:影响机制与提升策略

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中国农业大学学报 2024年第2期29卷 205-215页

作者：侯博刘强江苏师范大学食品安全与农业绿色发展研究中心江苏徐州221116

为提升公众食品安全风险治理参与意愿,基于扩展的计划行为理论和态度-情境-行为理论构建分析框架,借助微观调查数据,采用结构方程模型、bootstrap中介效应检验法和分层回归法对公众食品安全治理参与意愿的影响机制进行实证研究。结果表... 详细信息

为提升公众食品安全风险治理参与意愿,基于扩展的计划行为理论和态度-情境-行为理论构建分析框架,借助微观调查数据,采用结构方程模型、bootstrap中介效应检验法和分层回归法对公众食品安全治理参与意愿的影响机制进行实证研究。结果表明:1)行为态度、主观规范、知觉行为控制、感知风险和过去经历对公众食品安全治理参与意愿有显著正向影响,2)行为态度在感知风险、过去经历与参与意愿关系中发挥中介作用,3)政策规制在行为态度与参与意愿关系中发挥调节作用。因此,应从提高公众食品安全风险认知、优化公众食品安全治理参与体验、改善公众食品安全治理参与态度、营造促进公众参与的政策环境等方面提升公众食品安全风险治理参与意愿,推进食品安全风险社会共治。

关键词：食品安全风险公众参与社会共治中介效应结构方程模型

椭圆鞍形单层正交索网结构解析计算方法与形态优化

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工程力学 2024年第1期41卷 103-113页

作者：王博厚孙逊方立新东南大学土木工程学院江苏南京210096 东南大学建筑设计研究院有限公司江苏南京210096 东南大学建筑学院江苏南京210096

常见的单层正交索网结构由马鞍面和椭圆柱面相切而成,该类型结构在国内外的大型场馆、公共建筑中得到广泛应用。该文提出一种连续化解析计算方法,以求解椭圆鞍形单层正交索网结构的变形、内力和最优形态,求解过程中仅需解一元方程。计... 详细信息

常见的单层正交索网结构由马鞍面和椭圆柱面相切而成,该类型结构在国内外的大型场馆、公共建筑中得到广泛应用。该文提出一种连续化解析计算方法,以求解椭圆鞍形单层正交索网结构的变形、内力和最优形态,求解过程中仅需解一元方程。计算方法利用平衡方程、变形协调方程,以竖向位移为未知量,推导了正交单层索网连续化计算公式,采用伽辽金法求得近似解。在此基础上,以外环梁平面内弯矩最小为优化目标,以中央承重索垂度为优化变量,以索力、竖向位移和矢跨比为约束条件,利用外环梁弯矩计算公式,通过求解方程得到结构的最优形态并给出优化流程。最后对一个简单算例分别采用有限元法与解析法计算,验证了解析法所得位移、索力、外环弯矩和形态优化结果的准确性。在结构初步设计阶段,利用该解析计算方法,可快速得到荷载态下结构的位移、受力情况和最优形态,避免了有限元法编程、反复试算的繁杂过程。

关键词：单层索网结构解析解连续化理论形态优化有限元

维普期刊数据库博看期刊

科技期刊在公众科学素养提升中的传播困境与优化路径研究

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出版发行研究 2024年第5期 51-58,85页

作者：侯波刘明寿江苏经贸职业技术学院期刊社扬州大学学报编辑部

提升公民科学素养是社会主义精神文明建设的重要组成部分,也是科技期刊的重要社会功能。因此,科技期刊应积极担当起提升公众科学素养的使命。然而,目前我国科技期刊在传播方面仍存在不足,去中心化削弱科技期刊在公众科学素养提升中的权... 详细信息

提升公民科学素养是社会主义精神文明建设的重要组成部分,也是科技期刊的重要社会功能。因此,科技期刊应积极担当起提升公众科学素养的使命。然而,目前我国科技期刊在传播方面仍存在不足,去中心化削弱科技期刊在公众科学素养提升中的权威性,圈层文化造成科技期刊传播的自闭式生态模式,信息茧房加剧读者在获取科学知识过程中的认知偏差,数字镜像期刊扰乱学术市场的正常秩序,导致一些优质科学资源未能准确传达给读者。可以采取推动刊媒融合发展、构建社会化科普工作新格局,搭建新媒体传播矩阵、适应公众需求精准科普,共建学术生态圈、提升科学普及软实力等措施来全面提升科技期刊的传播能力,以满足公众的需求并精确传递科学资源,从而推动公众科学素养的提升。

关键词：科技期刊新媒体传播力公民素养

Assessment of cheese sign and its association with vascular risk factors:Data from PUMCH dementia cohort

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Chinese Medical Journal 2024年第7期137卷 830-836页

作者： Xinying Huang bo hou Jie Wang Jie Li Li Shang Chenhui Mao Liling Dong Caiyan Liu Feng Feng Jing Gao Bin Peng Department of Neurology State Key Laboratory of Complex Severe and Rare DiseasePeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Radiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Background:In the clinic,practitioners encounter many patients with an abnormal pattern of dense punctate magnetic resonance imaging(MRI)signal in the basal ganglia,a phenomenon known as"cheese sign".This sign is reported as common in cerebrovascular diseases,dementia,and old ***,cheese sign has been speculated to consist of dense perivascular space(PVS).This study aimed to assess the lesion types of cheese sign and analyze the correlation between this sign and vascular disease risk ***:A total of 812 patients from Peking Union Medical College Hospital(PUMCH)dementia cohort were *** analyzed the relationship between cheese sign and vascular *** assessing cheese sign and defining its degree,the abnormal punctate signals were classified into basal ganglia hyperintensity(BGH),PVS,lacunae/infarctions and microbleeds,and counted *** type of lesion was rated on a four-level scale,and then the sum was calculated;this total was defined as the cheese sign *** and Age-Related White Matter Changes(ARWMC)scores were used to evaluate the paraventricular,deep,and subcortical gray/white matter ***:A total of 118 patients(14.5%)in this dementia cohort were found to have cheese ***(odds ratio[OR]:1.090,95%confidence interval[CI]:1.064-1.120,P<0.001),hypertension(OR:1.828,95%CI:1.123-2.983,P=0.014),and stroke(OR:1.901,95%CI:1.092-3.259,P=0.025)were risk factors for cheese *** was no significant relationship between diabetes,hyperlipidemia,and cheese *** main components of cheese sign were BGH,PVS,and lacunae/*** proportion of PVS increased with cheese sign ***:The risk factors for cheese sign were hypertension,age,and *** sign consists of BGH,PVS,and lacunae/infarction.

关键词： Dementia Cerebrovascular disease Cheese sign Dense punctate lesions Basal ganglia Risk factor White matter

Upper extremity motor function before and after the cerebrospinal fluid tap test in patients with idiopathic normal pressure hydrocephalus:A retrospective study

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Chinese Medical Journal 2024年第7期137卷 877-879页

作者： Caiyan Liu Junji Wei Liling Dong Chenhui Mao Jie Li Xinying Huang bo hou Feng Feng Liying Cui Jing Gao Department of Neurology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Department of Neurosurgery Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China Department of Neurosurgery and Radiology Peking Union Medical College HospitalChinese Academy of Medical SciencesBeijing 100730China

To the Editor:Idiopathic normal pressure hydrocephalus(iNPH)patients present disturbances in gait,cognition,and/or control of urination with neuroimaging characterized by enlargement of the cerebral ***,gait disturbance in iNPH patients is the initial and most prominent symptom,but motor impairments can also extend to upper *** cerebrospinaluid(CSF)tap test(TT),in which the symptoms of iNPH patients are assessed before and after drainage of 30-50mL CSF by lumbar puncture,is a commonly used auxiliary test for predicting shunt *** methods for determining the CSF TT response are based on the clinical impression of changes in gait after lumber *** patients who are unable to ambulate(e.g.,the patient is wheelchair bound)may not be able to comply with the gait evaluation but still benet from shunt *** grooved pegboard test(GPT)and symbol-digit modalities test(SDMT)are psychometric measures of upper extremity motor and psychomotor ***,we sought to identify whether these tests could be used to objectively assess responsiveness to the CSF TT.

关键词： patients cerebrospinal Upper