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Environmental analysis of innovative sustainable composites with potential use in aviation sector -A life cycle assessment review

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Science China(Technological Sciences) 2017年第9期60卷 1301-1317页

作者： BACHMANN Jens hidalgo carme RICOUT Stephanie Deutsches Zentrum fiir Lufi- und Raumfahrt e. V. (German Aerospace Centre) Institute of Composite Structures and Adaptive Systems-Department of Multifunctional Materials Lilienthalplatz 7 38108 Braunsehweig Germany Leitat Technological Center C/Innovacio 2 08225 Terrassa Spain Airbus Group Innovations Fuels and Environment 12 rue Pasteur 92152 Suresnes France

The forecast of growing air transport in the upcoming decades faces the challenge of an increasing environmental *** industry is working on promising technologies to mitigate this environmental *** design is a strong lever to lower the fuel consumption and,consequently,with it the emissions of *** performance composites are a key technology to help achieve these aims thanks to their favourable combination of mechanical properties and low weight in primary ***,mainly synthetic materials such as petrol based carbon fibres and epoxy resins are used nowadays to produce composite in *** materials like bio-based fibres and resin systems offer potential environmental ***,they have not found their way into aviation,*** reasons are reduced mechanical properties and,especially for the use of natural fibres,their *** of these shortcomings are under *** the application of bio-based and recycled materials in certain areas of the aircraft could be possible in the *** examples for applications are furnishings and secondary *** motivation for this paper is to give an overview of potential environmental properties by using such eco-materials in *** cycle assessment(LCA) is a tool to calculate environmental impacts during all life stages of a *** main focus is laid on the bio-fibres flax and ramie,recycled carbon fibres and bio-based thermoset resin *** an overview of environmental aspects of existing composite materials used in aviation is ***,a lack of LCA results for the substitution of synthetic materials by bio-based/recycled composite materials in aviation applications has been ***,available information from other transport areas,such as automotive,has been *** detailed LCA data for eco-composite materials and technologies to improve their properties is import

关键词： aviation composite natural fibre recycled carbon fibre bio-resin cabin interior secondary structure,fife cycle assessment (LCA)

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Optimal Design of Hybrid Microgrid in Isolated Communities of Ecuador

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 488-499页

作者： Luis A.Pesantes Ruben hidalgo-León Johnny Rengifo Miguel Torres Jorge Aragundi JoséCordova-Garcia Luis F.Ugarte Facultad de Ingeniería en Electricidad y Computación of Escuela Superior Politécnica del Litoral(ESPOL)University GuayaquilEcuador Department of Electrical Engineering at Universidad Técnica Federico Santa María SantiagoChile IEEE

In rural territories, the communities use energy sources based on fossil fuels to supply themselves with electricity, which may address two main problems: greenhouse gas emissions and high fuel prices. Hence, there is an opportunity to include renewable resources in the energy mix. This paper develops an optimization model to determine the optimal sizing, the total annual investment cost in renewable generation, and other operating costs of the components of a hybrid microgrid. By running a k-means clustering algorithm on a meteorological dataset of the community under study, the hourly representative values become input parameters in the proposed optimization model. The method for the optimal design of hybrid microgrid is analyzed in six operating scenarios considering:(1) 24-hour continuous power supply;(2) load shedding percentage;(3) diesel power generator(genset) curtailment;(4) the worst meteorological conditions;(5) the use of renewable energy sources including battery energy storage systems(BESSs);and(6) the use of genset. A mathematical programming language(AMPL) tool is used to find solutions of the proposed optimization model. Results show that the total costs of microgrid in the scenarios that cover 100% of the load demand(without considering the scenario with 100% renewables) increase by over 16% compared with the scenario with genset operation limitation. For the designs with power supply restrictions, the total cost of microgrid in the scenario with load shedding is reduced by over 27% compared with that without load shedding.

关键词： Battery energy storage system(BESS) isolated community microgrid renewable energy optimization

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Metastatic pancreatic and lung cancer patient in complete remission following immunotherapy: A case report and review of literature

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World Journal of Gastrointestinal Oncology 2024年第5期16卷 2233-2240页

作者： Joaquina Martínez-Galán Cristina Jiménez-Luna Isabel Rodriguez Elisabeth Maza Carlos García-Collado Antonio Rodríguez-Fernández Javier Luis López-hidalgo Octavio Caba Department of Medical Oncology Virgen de las Nieves University HospitalGranada 18014Spain Instituto de Investigación Biosanitaria Ibs.GranadaGranada 18012Spain Institute of Biopathology and Regenerative Medicine(IBIMER) University of GranadaGranada 18016Spain Pharmacogenetics Unit Virgen de las Nieves University HospitalGranada 18014Spain Department of Medicina Nuclear Virgen de las Nieves University HospitalGranada 18014Spain Department of Anatomía Patológica Virgen de las Nieves University HospitalGranada 18014Spain

BACKGROUND Metastatic pancreatic ductal adenocarcinoma(PDAC)is a lethal malignancy with dispiriting survival *** is a promising approach to many cancer types,but achieves poor outcomes in advanced PDAC due to its immunosuppressive tumor *** describe a case of metastatic PDAC effectively treated with *** SUMMARY We report the case of a 67-year-old woman with unresectable locally advanced PDAC,treated with gemcitabine plus nab-paclitaxel followed by radiotherapy plus *** nine months,pancreatic tumor progression was observed at the level of the hepatic hilum with the appearance of a new pulmonary nodule suggestive of a second primary,confirmed by left lung *** immunotherapy was then initiated with pembrolizumab,an immune checkpoint inhibitor targeting programmed cell death protein-1 that covers the two tumor *** patient showed a complete metabolic response that was maintained throughout the *** patient continues to be disease-free at 5.6 years since the start of *** These results suggest that the administration of pembrolizumab after chemoradiotherapy has a beneficial effect in patients with metastatic *** our knowledge,this is the first reported case of a patient with metastatic PDAC and metastatic lung cancer showing such a long-lasting complete response after pembrolizumab treatment without curative *** studies are required to determine biomarkers that identify PDAC patients most likely to benefit from this immunotherapy.

关键词： Pancreatic ductal adenocarcinoma Lung cancer Immunotherapy Pembrolizumab Programmed cell death protein-1 Case report

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Physical activity and amyloid beta in middle-aged and older adults:A systematic review and meta-analysis

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Journal of Sport and Health Science 2024年第2期13卷 133-144页

作者： María Rodriguez-Ayllon Patricio Solis-Urra Cristina Arroyo-ávila Miriam álvarez-Ortega Pablo Molina-García Cristina Molina-hidalgo Manuel Gómez-Río Belinda Brown Kirk I.Erickson Irene Esteban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and Social Sciences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Physical Medicine and Rehabilitation Service Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Psychology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia School of Medical and Health Sciences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health Research Institute Neuroscience Institute OrlandoOrlandoFL 32803USA Physiopathology of Obesity and Nutrition Research Center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels *** aimed to explore the relationship between physical activity and Aβin middle-aged and older ***:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,*** were eligible if they included physical activity and Aβdata in adults aged 45 years or ***-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβ***:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and *** physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older ***,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included *** observational studies,higher levels of physical activity were positively associated with Aβonly in ***,further research is needed t

关键词： Aging Cognitive impairment Dementia Exercise PET

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Numerical Approach of a Coupled Pressure-Saturation Model Describing Oil-Water Flow in Porous Media

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Communications on Applied Mathematics and Computation 2023年第2期5卷 946-964页

作者： Paula Luna Arturo hidalgo ISIS Neutron and Muon Source Rutherford Appleton LaboratoryDidcot OX110QXUK Departamento de Ingeniería Geológica y Minera Escuela Técnica Superior de Ingenieros de Minas y EnergíaCenter for Computational SimulationUniversidad Politécnica de MadridRíos Rosas2128003 MadridSpain

Two-phase flow in porous media is a very active field of research,due to its important applications in groundwater pollution,CO_(2)sequestration,or oil and gas production from petroleum reservoirs,just to name a few of *** flow equations,which make use of Darcy's law,for describing the movement of two immiscible fluids in a porous medium,are among the most relevant mathematical models in reservoir *** work aims to solve a fractional flow model formed by an elliptic equation,representing the spatial distribution of the pressure,and a hyperbolic equation describing the space-time evolution of water *** numerical solution of the elliptic part is obtained using a finite-element(FE)scheme,while the hyperbolic equation is solved by means of two dif-ferent numerical approaches,both in the finite-volume(FV)*** is based on a monotonic upstream-centered scheme for conservation laws(MUSCL)-Hancock scheme,whereas the other makes use of a weighted essentially non-oscillatory(ENO)*** both cases,a first-order centered(FORCE)-αnumerical scheme is applied for inter-cell flux reconstruction,which constitutes a new contribution in the field of fractional flow models describing oil-water movement.A relevant feature of this work is the study of the effect of the parameterαon the numerical solution of the models *** also show that,in the FORCE-αmethod,when the parameterαincreases,the errors diminish and the order of accuracy is more properly attained,as verified using a manufactured solution technique.

关键词： Two-phase flow Reservoir simulation Porous media FORCE-α Finite volume

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Allophane as a Nanotechnological Additive in Masonry Materials to Increase Resistance and Waterproofing

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Advances in Materials Physics and Chemistry 2024年第8期14卷 196-212页

作者： Edward H. Jiménez Joao Rivera Juan H. Villalba Paola E. Vera Marlon Cuenca Belén Granja Javier Fuentes Sandra Gavilanes Daniel hidalgo Fernando Garcia Jose Bermudez Washington Ruiz Alexis Martial Debut Facultad de Ingeniera Qumica Universidad Central del Ecuador Quito Ecuador Facultad de Arquitectura y Urbanismo Universidad Central del Ecuador Quito Ecuador Nanomaterials Characterization Laboratory Universidad de las Fuerzas Armadas ESPE Sangolqu Ecuador

The constant need for high-strength materials in the construction industry promotes the research of additives that improve the properties of masonry materials. The use of allophane as an additive in concrete and mortar mixtures was implemented to improve their strength and waterproofing, respectively, using compression and water absorption tests according to their corresponding standards (ASTM C1231, ASTM D2938, and ASTM C1585). The samples were evaluated at different concentrations and curing ages. In addition, different sand/cement ratios were considered for the mortar. The results revealed that there was a 9.4% increase in compressive strength in concrete and a 23.7% reduction in water absorption in mortar for the 5:1 ratio. These changes would be the result of the interaction of the nanoporous additive in the atomic crystal structure of the material demonstrating the nanotechnological nature of allophane.

关键词： Allophane Nano Additive Strength Impermeability Concrete Mortar

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Implicit large eddy simulation of unsteady cloud cavitation around a plane-convex hydrofoil

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Journal of Hydrodynamics 2015年第6期27卷 815-823页

作者： hidalgo Victor 罗先武 ESCALER Xavier 季斌 AGUINAGA Alvaro Beijing Key Laboratory of CO2 Utilization and Reduction Technology Tsinghua University CDIF Universitat Politècnica de Catalunya School of Power and Mechanical Engineering Wuhan University Mechanical Engineering Department Escuela Politecnica Nacional University

The present paper focuses on the erosive cavitation behavior around a plane convex hydrofoil. The Zwart-Gerber-Belamri cavitation model is implemented in a library form to be used with the OpenFOAM. The implicit large eddy simulation （ILES） is app- lied to analyze the three-dimensional unsteady cavitating flow around a plane convex hydrofoil. The numerical results in the cases under the hydrodynamic conditions, which were experimentally tested at the high speed cavitation tunnel of the l^cole Polytechnique F6d＆ale de Lausanne （EPFL）, clearly show the sheet cavitation development, the shedding and the collapse of vapor clouds. It is noted that the cavitation evolutions including the maximum vapor length, the detachment and the oscillation frequency, are captured fairly well. Furthermore, the pressure pulses due to the cavitation development as well as the complex vortex structures are reasona- bly well predicted. Consequently, it may be concluded that the present numerical method can be used to investigate the unsteady cavitation around hydrofoils with a satisfactory accuracy.

关键词： implicit large eddy simulation (ILES) unsteady partial cavitation Zwart-Gerber-Belamri cavitation model OpenFOAM,Q - criterion

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Alternatives to left lateral sector in paediatric liver transplantation-a systematic review on monosegmental and reduced grafts

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Hepatobiliary Surgery and Nutrition 2022年第4期11卷 567-576,I0005页

作者： Paschalis Gavriilidis Ernest hidalgo Department of Hepatopanceaticobiliary Surgery.Imperial College Healthcare NHS Trust Hammersmith HospitalLondonUK Department of Hepato-Pancreatic-Biliary Surgery and Liver Transplantation Hospital Universitari Vall d’HebronBarcelonaSpain

Background: Paediatric liver transplantation (pLT) is the treatment of choice for many liver conditions. However, it still poses relevant challenges, mainly related to the size of the recipients. Unlike in adults, excessive graft volume might represent an issue when the estimated graft-recipient-weight-ratio (GRWR) is significantly disproportionate. In this situation, the traditional left lateral sector (LLS) grafts are too big and other alternatives are required, such as monosegmental or reduced (including hyper-reduced) grafts (RLLS/HRLLS). Results with conventional LLS-pLT are excellent and replicating them with monosegmental or RLLS is challenging given (I) the technical complexity and (II) the need to overcome the large-for-size scenario. This article is to review the existing experience with monosegmental, RLLS/HRLLS grafts and appraise its results. Methods: Systematic search of the electronic databases, conducted from their inception until May 2020. Results: After scrutiny of the available literature, 16 studies were included reporting 330 patients transplanted with monosegmental and RLLS/HRLLS grafts. There were 10 re-grafts (6 of them <90 days);90% of grafts were LDLT. Overall, median recipient’s age and weight were 7 months (range, 5 days-22 months) and 5.8 kg (range, 2.6-8 kg) respectively. Median graft weight was 209 grams (range, 124-264 grams) and median GRWR was 3.5% (range, 2.7-5.6%). Hepatic artery and portal vein thrombosis overall incidence were 1.5% and 4.2%;120 out of the 330 pLT were monosegmental (37%) producing a smaller graft (median of 164 grams) and accordingly a lower GRWR (median 3.2%) compared to reduced LLS. With a median follow-up of 39 months (range, 6-87 months), the overall graft and patient survival were 84% (285/340) and 89% (295/330). Discussion: Monosegmental and RLLS/HRLLS grafts provide access to liver transplantation for very small recipients with excellent results comparable to the standard LLS.

关键词： Monosegmental monosegment(MSG) reduced hyper-reduced left lateral sector graft liver transplantation

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Interaction of silver nanoparticles with mediterranean agricultural soils: Lab-controlled adsorption and desorption studies

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Journal of Environmental Sciences 2019年第9期31卷 205-216页

作者： Laura Torrent Eva Margui Ignasi Queralt Manuela hidalgo Monica Iglesias Department of Chemistry University of Girona C/M. Aurelia Capmany 69 17003 Girona Spain Institute of Environmental Assessment and Water Research (IDAEA-CSIC) C. Jordi Girona 28-26 08034 Barcelona Spain

The production of silver nanoparticles(AgNPs) has increased tremendously during recent years due to their antibacterial and physicochemical properties. As a consequence, these particles are released inevitably into the environment, with soil being the main sink of disposal. Soil interactions have an effect on AgNP mobility, transport and bioavailability. To understand AgNP adsorption processes, lab-controlled kinetic studies were *** tests performed with five different Mediterranean agricultural soils showed that cation exchange capacity and electrical conductivity are the main parameters controlling the adsorption processes. The adsorption kinetics of different sized(40, 75, 100 and 200 nm)and coated(citrate, polyvinylpyrrolidone and polyethyleneglycol(PEG)) AgNPs indicated that these nanoparticle properties have also an effect on the adsorption *** assess the mobility and bioavailability of AgNPs and to determine if their form is maintained during adsorption/desorption processes, loaded soils were submitted to leaching tests three weeks after batch adsorption studies. The DIN 38414-S4 extraction method indicated that AgNPs were strongly retained on soils, and single-particle inductively coupled plasma mass spectrometry confirmed that silver particles maintained their nanoform, except for 100 nm PEG-AgNPs and 40 nm citrate-coated AgNPs. The DTPA(diethylenetriaminepentaacetic acid) leaching test was more effective in extracting silver,but there was no presence of AgNPs in almost all of these leachates.

关键词： Silver nanoparticles Agricultural soils Sorption kinetics Leaching tests Single-particle inductively coupled plasma mass spectrometry

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Discretized Miller approach to assess effects on boundary layer ingestion induced distortion

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Chinese Journal of Aeronautics 2017年第1期30卷 235-248页

作者： Esteban Valencia Víctor hidalgo Devaiah Nalianda Laskaridis Panagiotis Riti Singh Departamento de Ingeniería Mecánica Facultad de Ingeniería Mecánica Escuela Politécnica Nacional Ladron de Guevara E11-253 Quito 17-01-2759 Ecuador School of Engineering Cranfield University Bedford MK430AL United Kingdom

The performance of propulsion configurations with boundary layer ingestion（BLI） is affected to a large extent by the level of distortion in the inlet flow field. Through flow methods and parallel compressor have been used in the past to calculate the effects of this aerodynamic integration issue on the fan performance; however high-fidelity through flow methods are computationally expensive, which limits their use at preliminary design stage. On the other hand, parallel compressor has been developed to assess only circumferential distortion. This paper introduces a discretized semi-empirical performance method, which uses empirical correlations for blade and performance calculations. This tool discretizes the inlet region in radial and circumferential directions enabling the assessment of deterioration in fan performance caused by the combined effect of both distortion patterns. This paper initially studies the accuracy and suitability of the semiempirical discretized method by comparing its predictions with CFD and experimental data for a baseline case working under distorted and undistorted conditions. Then a test case is examined,which corresponds to the propulsor fan of a distributed propulsion system with BLI. The results obtained from the validation study show a good agreement with the experimental and CFD results under design point conditions.

关键词： BLI Correlations Distortion Embedded propulsors Empirical Mean-line analysis Turbomachinery

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