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Quantitative in situ measurement of optical force along a strand of cleaved silica optical fiber induced by the light guided therewithin

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Photonics Research 2021年第10期9卷 2016-2023页

作者： MIKKO partanen HYEONWOO LEE KYUNGHWAN OH Photonic Device Physics Laboratory Department of PhysicsYonsei UniversitySeoul 03722Republic of Korea Photonics Group Department of Electronics and NanoengineeringAalto University00076 AaltoFinland

We propose an optomechanical system to quantify the net force on a strand of cleaved silica optical fiber in situ as the laser light is being guided through *** strands of the fiber were bonded to both sides of a macroscopic oscillator,whose movements were accurately monitored by a Michelson *** laser light was propagating with variable optical powers and frequency ***,we discovered that the driving force for the oscillator consisted of not only the optical force of the light exiting from the cleaved facets but also the tension along the fiber induced by the light guided *** net driving force was determined only by the optical power,refractive index of the fiber,and the speed of light,which pinpoints its fundamental origin.

关键词： fiber optical interferometer

Unveiling bulk and surface radiation forces in a dielectric liquid

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Light(Science & Applications) 2022年第5期11卷 925-934页

作者： N.G.C.Astrath G.A.S.Flizikowski B.Anghinoni L.C.Malacarne M.L.Baesso T.Požar M.partanen I.Brevik D.Razansky S.E.Bialkowski Department of Physics Universidade Estadual de MaringáMaringáPRBrazil Faculty of Mechanical Engineering University of LjubljanaLjubljanaSlovenia Department of Electronics and Nanoengineering Aalto UniversityAaltoFinland Department of Energy and Process Engineering Norwegian University of Science and TechnologyTrondheimNorway Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology Faculty of MedicineUniversity of ZurichZurichSwitzerland Institute for Biomedical Engineering Department of Information Technology and Electrical EngineeringETH ZurichZurichSwitzerland Department of Chemistry and Biochemistry Utah State UniversityLoganUTUSA

Precise control over light-matter interactions is critical for many optical manipulation and material characterization methodologies,further playing a paramount role in a host of nanotechnology ***,the fundamental aspects of interactions between electromagnetic fields and matter have yet to be established unequivocally in terms of an electromagnetic momentum ***,we use tightly focused pulsed laser beams to detect bulk and boundary optical forces in a dielectric *** the optical convoluted signal,we decouple thermal and nonlinear optical effects from the radiation forces using a theoretical interpretation based on the Microscopic Ampère force *** is shown,for the first time,that the time-dependent pressure distribution within the fluid chiefly originates from the electrostriction *** results shed light on the contribution of optical forces to the surface displacements observed at the dielectric air-water interfaces,thus shedding light on the long-standing controversy surrounding the basic definition of electromagnetic momentum density in matter.

关键词： dielectric momentum surface

Immunogenetic characteristics of patients with autoimmune gastritis

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World Journal of Gastroenterology 2010年第3期16卷 354-358页

作者： Aino Mirjam Oksanen Katri Eerika Haimila Hilpi Iris Kaarina Rautelin Jukka Antero partanen Herttoniemi Hospital Health Centre Finnish Red Cross Blood Service Clinical Laboratory Department of Bacteriology and Immunology Haartman InstituteUniversity of Helsinki HUSLAB Helsinki University Central Hospital Department of Medical Sciences University and University Hospital of Uppsala Finnish Red Cross Blood Service Research and Development

AIM:To explore whether predisposition to autoimmune gastritis (AIG) is found in human leukocyte antigen (HLA), cytokine or killer cell immunoglobulin-like receptor (KIR) gene ***: Twelve Finnish patients with autoimmunetype severe atrophy of the gastric corpus were included. The patients' serum was analyzed for pepsinogen-interleukin (IL)-1 gene cluster, IL-2, IL-4, IL-6, IL-10, IL-12, interferon γ, transforming growth factor β, and tumor necrosis factor α. Variation in KIR genes was also explored. The results were compared with prevalence of the polymorphisms in Finnish or European ***: All patients had pepsinogen-CONCLUSION: As explored with modern DNA-based methods, HLA-DRB1*04 and DQB1*03 alleles, but not HLA-B8-DRB1*03, may predispose to AIG.

关键词： Atrophic gastritis Autoimmune diseases Cytokines Genetic polymorphisms Human leukocyte antigens Killer cell immunoglobulin-like receptor

Endomysial antibodies predict celiac disease irrespective of the titers or clinical presentation

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World Journal of Gastroenterology 2012年第20期18卷 2511-2516页

作者： Kalle Kurppa Tiia Rsnen Pekka Collin Sari Iltanen Heini Huhtala Merja Ashorn Pivi Saavalainen Katri Haimila Jukka partanen Markku Mki Katri Kaukinen Pediatric Research Centre University of Tampere and Tampere University HospitalFin-33014Tampere Finland Department of Gastroenterology and Alimentary Tract Surgery Tampere University Hospital and School of MedicineUniversity of TampereFin-33014 TampereFinland Tampere School of Public Health University of TampereFin-33014TampereFinland Department of Medical Genetics and Research Program for Molecular Medicine University of Helsinki Fin-00014HelsinkiFinland Research and Development Finnish Red Cross Blood ServiceFin-00310HelsinkiFinland

AIM:To investigate the association between serum antibody levels and a subsequent celiac disease diag-nosis in a large series of children and adults. METHODS:Besides subjects with classical gastrointestinal presentation of celiac disease,the study cohort included a substantial number of individuals with extraintestinal symptoms and those found by screening in at-risk *** 405 patients underwent clinical,serological and histological *** collection of data,the antibody values were further graded as low[endomysial(EmA)1:5-200,transglutaminase 2 antibodies(TG2-ab)5.0-30.0 U/L]and high (EmA 1:≥500,TG2-ab≥30.0 U/L),and the serological results were compared with the small intestinal mucosal histology and clinical presentation. RESULTS:In total,79%of the subjects with low and 94%of those with high serum EmA titers showed small-bowel mucosal villous ***, 96%of the 47 EmA positive subjects who had normal mucosal villi and remained on follow-up either subsequently developed mucosal atrophy while on a glutencontaining diet,or responded positively to a glutenfree diet. CONCLUSION:Irrespective of the initial serum titers or clinical presentation,EmA positivity as such is a very strong predictor of a subsequent celiac disease diagnosis.

关键词：疾病诊断临床表现抗体水平腹腔滴度预测内膜转谷氨酰胺酶

为您的产品选择正确的理念——美卓低定量箱纸板生产技术

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中华纸业 2009年第1期30卷 74-79页

作者： Kari Raisanen Hannu partanen Hannu Turpeinen 美卓造纸机械公司纸和纸板机

重点介绍了美卓造纸机械公司研发的ValFormer靴刮刀叠网成形技术、OptiFormer夹网成形器和OptiFormer型流浆箱，以便为使用较高比例的混合废纸且在更高的车速下生产更低定量瓦楞原纸以及挂面纸板时，获得高效、低能耗和理想质量的产品。

关键词：低定量箱纸板混合废纸纸幅成形 ValFormer靴刮刀叠网成形技术 OptiFormer夹网成形器 OptiFlo II型流浆箱美卓

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新辊面包覆降低能耗

中华纸业 2014年第16期35卷 68-69页

作者： Juhani partanen 维美德公司

纸与纸板生产属于能耗密集型产业，大部分能量用于流浆箱前的磨木、筛选等备浆工段以及烘干部的蒸发脱水。截至目前，人们研究的重点一直是如何降低这些工艺段的能耗。然而，通过强化压榨脱水，可大幅降低压榨部的传动能耗和烘干部的干... 详细信息

纸与纸板生产属于能耗密集型产业，大部分能量用于流浆箱前的磨木、筛选等备浆工段以及烘干部的蒸发脱水。截至目前，人们研究的重点一直是如何降低这些工艺段的能耗。然而，通过强化压榨脱水，可大幅降低压榨部的传动能耗和烘干部的干燥能耗，由此而产生的成本效益也相当明显。

关键词：辊面包覆材料聚氨酯能源消耗维美德

高速新概念成形——低定量双层箱纸板,变不可能为可能

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中华纸业 2010年第16期31卷 6-12页

作者： Teuvo Virkkunen Hannu Turpeinen Kari Risnen Hannu partanen

介绍了一种全新的、已获专利保护的、用单台混合成形单元生产容器用轻量双层箱纸板的成本效益型的概念。新概念将三个独特的部件和技术结合为一体:新型ValFloPro双层流浆箱、VacuBalence真空辅助成形板和ValFormer靴刮刀混合成形器技术... 详细信息

介绍了一种全新的、已获专利保护的、用单台混合成形单元生产容器用轻量双层箱纸板的成本效益型的概念。新概念将三个独特的部件和技术结合为一体:新型ValFloPro双层流浆箱、VacuBalence真空辅助成形板和ValFormer靴刮刀混合成形器技术。这个具备分层技术的混合成形新概念将纸机运行速度提高到1400m/min,是生产一流质量轻量箱纸板的一种切实可行的替代方案。

关键词：新概念 ValFlo Pro ValFormer

组织蛋白酶D缺乏导致人类先天性神经元蜡样脂褐质沉着症

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世界核心医学期刊文摘(神经病学分册) 2006年第11期 7-8页

作者： Siintola E partanen S Strmme P J. Tyynel 周永 Institute of Biomedicine/Biochemistry University of Helsinki Haartmaninkatu 8 00014 Helsinki Finland Dr.

Congenital neuronal ceroid-lipofuscinosis (NCL) is a devastating inherited neurodegenerative disorder of unknown metabolic basis. Eight patients with this rare disorder, all with similar clinical and neuropathological findings, have been reported, and here we describe two further patients. Previously, we showed that a mutation in the cathepsin D gene causes congenital NCL in sheep. On the basis of the neuropathological and ultrastructural similarities between the sheep and patients affected with congenital NCL, we screened the cathepsin D gene for mutations in a patient of Pakistani origin. We identified a nucleotide duplication, c.764dupA, in the cathepsin D gene in homozygous form in the patient, and in heterozygous form in his father. This duplication is likely to be disease causing, as it creates a premature stop codon, predicting a truncation of the protein. When transiently expressed in cell cultures, the mutant protein was enzymatically inactive, but stable. In paraffin-embedded brain tissue samples of two affected siblings of the Pakistani patient, cathepsin D was absent, suggesting rapid degradation of the c.764dupA mutant cathepsin D at mRNA or protein level in vivo. Further, we were able to confirm lack of cathepsin D in the brain tissue of yet another, unrelated, patient of English origin with congenital NCL. On the basis of the present data, and the nearly identical clinical and/or pathological phenotype of the other reported cases of congenital NCL, it is reasonable to suggest that cathepsin D deficiency caused by mutations in the corresponding gene may underlie all cases of congenital NCL. The present observations also suggest that cathepsin D deficiency should be considered as a possible diagnosis in microcephalic neonates, who present with seizures at or before birth.

关键词：组织蛋白酶基因突变脂褐质点突变蜡样神经组织神经元

小儿硫喷妥钠／七氟烷麻醉及复合使用酮洛芬和芬太尼对刺激正中神经的体感诱发电位的影响

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麻醉与镇痛 2012年第2期8卷 73-79页

作者： Susanna Westeren-Punnone~ Heidi Ypparila-Wolters Juhani partanen Kari Nieminen, MD Antti Hyvarinen, MD Hannu Kokki, MD, PhD 郭娜（译）陈秉学（校） Department of Clinical Neurophysiology Kuopio University Hospital Finland VTT Infor-mation Technology Tampere Finland Department of Clinical Neurophysiology HelsinkiUniversity Hospital Jorvi Hospital Espoo Finland Department of Anesthesiology and In-tensive Care Kuopio University Hospital Finland Department of Otorhinolaryngology Kuopio University Hospital Finland Department of Pharmacology and Toxicology Univer-sity of Kuopio

背景体感诱发电位（somatosensory evoked potentials，SEPs）常被用于外科手术中判断脊髓和脑功能。总的来说，SEPs对吸入性麻醉药物是敏感的，但有关小儿用七氟烷维持麻醉对sEPs的影响了解甚少。麻醉中常会使用镇痛药物，辅助用药也... 详细信息

背景体感诱发电位（somatosensory evoked potentials，SEPs）常被用于外科手术中判断脊髓和脑功能。总的来说，SEPs对吸入性麻醉药物是敏感的，但有关小儿用七氟烷维持麻醉对sEPs的影响了解甚少。麻醉中常会使用镇痛药物，辅助用药也会影响SEPs。在这项前瞻性的临床试验中，共计27例3。8岁的健康儿童接受研究，对其静脉给予苯二氮革和巴比妥类药物麻醉诱导后，用七氟烷维持麻醉，并观察它们对正中神经SF2s的影响。此外，也观察了两种镇痛药物，酮洛芬和芬太尼对SEPs的影响。方法麻醉前静脉给予0．1mg／kg咪达唑仑，用呼气末浓度为2％的七氟烷维持麻醉，分别在给予咪达唑仑前，吸入七氟烷后15分钟、25分钟（给予或不给予酮洛芬）、35分钟（给予芬太尼）记录正中神经SEPs。结果与基础水平相比，应用七氟烷维持麻醉期间N20潜伏期延长（P=0．015），中枢传导时间延长（P=0．001）；使用镇痛药物对N20潜伏期和中枢传导时间并没有影响。5-8岁儿童的平均皮层N20-P25的振幅显著降低（P=0．008）。此外，对于年长的儿童，复合用酮洛芬和芬太尼后N20-P25振幅比使用前明显减低（P=0．03），而在年幼的儿童则没有这样的变化。讨论本研究发现，儿童使用2％七氟烷维持麻醉会延长正中神经的SEPs，与用其他吸入性麻醉药的报道相似。然而，吸入七氟烷时可以进行SEP的监测，但吸入的剂量应根据个体差异调整。复合使用酮洛芬和芬太尼不影响SEP的潜伏期，但posthoc分析结果提示，较年长的儿童皮层波幅会减低。

关键词：体感诱发电位正中神经复合使用氟烷麻醉芬太尼酮洛芬硫喷妥钠小儿