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Outcome of meniscal repairs in paediatric population:A tertiary centre experience

World Journal of Orthopedics 2024年第6期15卷 547-553页

作者： Ayman Gabr Samson Williams Sophie Dodd Nick Barton-hanson Department of Trauma&Orthopaedics West Suffolk HospitalSuffolk IP332QZUnited Kingdom Department of Trauma and Orthopaedics Alder Hey Children's HospitalLiverpool L145ABUnited Kingdom

BACKGROUND Meniscal sparing surgery is a widely utilised treatment option for unstable meniscal tears with the aim of minimising the risk of progression towards ***,there is limited data in the literature on meniscal repair outcomes in skeletally immature *** To evaluate the re-operation rate and functional outcomes of meniscal repairs in children and *** We performed a retrospective review of all patients who underwent arthroscopic meniscal repair surgery between January 2007 and January *** patients were under the age of 18 at the time of *** were all performed by a single *** was gathered from our hospital Electronic Patient Records *** primary outcome measure was re-operation rate(need for further surgery on the same meniscus).Secondary outcome measures were surgical complications and patient reported outcome measures that were International Knee Documentation Committee(IKDC),Tegner and Lysholm *** We identified 59 patients who underwent 66 All-inside meniscal repairs(32 medial meniscus and 34 Lateral meniscus).Meniscal repairs were performed utilizing FasT-Fix(Smith and Nephew)*** were 37 males and 22 females with an average age of 14 years(range 6-16).The average follow-up time was 53 months(range 26-140).Six patients had concomitant anterior cruciate ligament reconstruction surgery along with the meniscal *** were no requiring further meniscal repairs and 9 patients underwent partial *** mean postoperative IKDC score was 88(44-100),Tegner score was 7(2-10)and Lysholm score was 94(57-100).CONCLUSION Our results showed that arthroscopic repair of meniscal tears in the paediatric population is an effective treatment option that has a low failure rate and good postoperative clinical with the advantage of preserving meniscal tissues.

关键词： Meniscus Meniscal repair Outcome Meniscal preservation

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Mass communication :

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2005年

作者： Ralph E. hanson.

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Chinese Sources for AfterWards:From Premodern Poetry,Paintings,and Medical Texts to Modern Novels,Film,and Documentaries

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Chinese Medicine and Culture 2023年第2期6卷 127-138页

作者： Marta hanson Independent Scholar Max Planck Institute for the History of ScienceBerlin 14195Germany

This paper focuses on Chinese sources suggested for a narrative medicine(NM)program,called *** Lauren Small established AfterWards in 2014 and has been coordinating it since out of the Pediatrics Department at Johns Hopkins *** early 2019,she started giving a series of lectures and workshops about AfterWards to Chinese medical educators and clinicians in Beijing and *** created an AfterWards Facilitator’s Guide based on Western-language sources for workshop *** also started to organize with Jiang Yuhong(Peking Union Medical College)a workshop for Chinese colleagues to be held at Johns Hopkins Medicine in October *** invited the author to *** idea was hatched then to develop Chinese source materials following the AfterWards structure for an updated Facilitator’s Guide that Dr Small had initially written.A typical one-hour AfterWards session consists of a specific five-part structure:a literary text or artwork,an associated theme,discussion topics,a writing exercise,and shared *** the content of the program always changes from session to session,the basic structure remains the *** paper summarizes the types of Chinese sources and their related narrative-medicine themes that were originally selected for inclusion in the updated AfterWards Facilitator’s Guide intended for Chinese *** sources about coping with sick family members,aging,and illness ranged from the textual(classical Chinese poems on aging and diagnostic forms for training students)and visual(premodern Chinese paintings and murals of medical encounters)to the fictive(novels)and performative(contemporary Asian-American film in English and Chinese-language film and documentaries).

关键词： Documentaries Films Murals Narrative medicine Novels Paintings Poetry

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Grasping Heaven and Earth(Qian Kun Zai Wo):The Body-as-Technology in Classical Chinese Medicine

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中医药文化(英文) 2023年第3期6卷 233-246页

作者： Marta hanson Independent Scholar Affiliate Max Planck Institute for the History of ScienceBerlin 14195Germany

Shifting focus from the patient’s body to the healer’s body,this essay focuses on how Chinese physicians instrumentalized their bodies to heal(ie,body-as-technology)and their hands to think with(ie,hand-memory techniques or simply,hand mnemonics).When physicians used their hands to memorize concepts related to clinical practice,calculate with time variables,and carry out ritual gestures intended to reduce risk,improve fortune,and even cure,their hands became extensions of their *** essay has three parts that follow the discovery process of the author’s research on hand-memory techniques found in Chinese medical *** first part“Divination and Revelation”explains the significance of how the author first learned about Chinese divination practices that used hand *** second part“Original Frame”introduces the scholarship on arts of memory in Europe that informed interpretations of the earliest hand mnemonics found in Chinese medical *** third part“Expanded Frame”deploys some concepts from cognitive science to help situate Chinese medical hand mnemonics more broadly as an example of extended *** essay concludes with an important distinction:sometimes Chinese healers’hands were used separately from their bodies to think through things and sometimes hand and body had to be integrated in order for the healer’s body-as-technology to act as a therapeutically effective instrument.

关键词： Arts of memory Body-as-technology Extended cognition Hand mnemonics

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Diversity-accuracy assessment of multiple classifier systems for the land cover classification of the Khumbu region in the Himalayas

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Journal of Mountain Science 2022年第2期19卷 365-387页

作者： Charisse Camacho hanson Lars BRABYN Sher Bahadur GURUNG Geography Programme University of WaikatoPrivate Bag 3105Hamilton 3240New Zealand Central Department of Geography Tribhuvan UniversityTU RdKirtipur 44618Nepal

Land cover classification of mountainous environments continues to be a challenging remote sensing problem,owing to landscape complexities exhibited by the *** study explored a multiple classifier system(MCS)approach to the classification of mountain land cover for the Khumbu region in the Himalayas using Sentinel-2 images and a cloud-based model *** relationship between classification accuracy and MCS diversity was investigated,and the effects of different diversification and combination methods on MCS classification performance were comparatively assessed for this *** present ten MCS models that implement a homogeneous ensemble approach,using the high performing Random Forest(RF)algorithm as the selected *** base classifiers of each MCS model were developed using different combinations of three diversity techniques:(1)distinct training sets,(2)Mean Decrease Accuracy feature selection,and(3)‘One-vs-All’problem *** base classifier predictions of each RFMCS model were combined using:(1)majority vote,(2)weighted argmax,and(3)a meta RF *** MCS models reported higher classification accuracies than the benchmark classifier(overall accuracy with 95% confidence interval:87.33%±0.97%),with the highest performing model reporting an overall accuracy(±95% confidence interval)of 90.95%±0.84%.Our key findings include:(1)MCS is effective in mountainous environments prone to noise from landscape complexities,(2)problem reduction is indicated as a stronger method over feature selection in improving the diversity of the MCS,(3)although the MCS diversity and accuracy have a positive correlation,our results suggest this is a weak relationship for mountainous classifications,and(4)the selected diversity methods improve the discriminability of MCS against vegetation and forest classes in mountainous land cover classifications and exhibit a cumulative effect on MCS diversity for this context.

关键词： Multiple classifier system Ensemble diversity Google Earth Engine Land Cover Classification Himalayas Random Forest

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Evaluating the quality of feed fats and oils and their effects on pig growth performance

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Journal of Animal Science and Biotechnology 2016年第3期7卷 330-340页

作者： Gerald C Shurson Brian J Kerr Andrea R hanson Department of Animal Science University of MinnesotaStPaulMN 55018USA usda-ars-national laboratory for agriculture and the environment Ames IA 50011USA svc-research St PeterMN 56082USA

Feed fats and oils provide significant amounts of energy to swine diets, but there is large variation in composition,quality, feeding value, and price among sources. Common measures of lipid quality include moisture, insolubles,and unsaponifiables（MIU）, titer, and free fatty acid content, but provide limited information regarding their feeding value. Lipid peroxidation is an important quality factor related to animal growth performance and health, but maximum tolerable limits in various lipids have not been established. Several indicative assays can be used to detect the presence of various peroxidation compounds, but due to the complexity and numerous compounds produced and degraded during peroxidation process, no single method can adequately determine the extent of peroxidation. Until further information is available, using a combination of peroxide value, thiobarbituric acid reactive substances（TBARS）, and anisidine value appear to provide a reasonable assessment of the extent of peroxidation in a lipid at a reasonable cost. However, fatty acid composition of the lipid being evaluated should be considered when selecting specific assays. Predictive tests can also be used to estimate the stability or susceptibility of lipids to peroxidation and include active oxygen method, oil stability index, and oxygen bomb method. A review of 16 published studies with pigs has shown an average decrease of 11.4% in growth rate, 8.8% feed intake fed isocaloric diets containing peroxidized lipids compared to diets containing unperoxidized lipids of the same ***, serum vitamin E content was generally reduced and serum TBARS content was increased when peroxidized lipids were fed in these studies, suggesting that feeding peroxidized lipids negatively affects metabolic oxidative status of pigs. However, it is unclear if antioxidants are useful additions to lipids to maintain optimal nutritional value, or if their addition to swine diets is beneficial in overcoming a met

关键词： Growth Indicative tests Lipids Metabolic oxidation Peroxidation Pigs

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SPOT-Disorder2: Improved Protein Intrinsic Disorder Prediction by Ensembled Deep Learning

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Genomics, Proteomics & Bioinformatics 2019年第6期17卷 645-656页

作者： Jack hanson Kuldip K.Paliwal Thomas Litfin Yaoqi Zhou Signal Processing Laboratory Griffith UniversityBrisbane 4111Australia School of Information and Communication Technology Griffith UniversityGold Coast 4222Australia Institute for Glycomics Griffith UniversityGold Coast 4222Australia

Intrinsically disordered or unstructured proteins(or regions in proteins) have been found to be important in a wide range of biological functions and implicated in many diseases. Due to the high cost and low efficiency of experimental determination of intrinsic disorder and the exponential increase of unannotated protein sequences, developing complementary computational prediction methods has been an active area of research for several decades. Here, we employed an ensemble of deep Squeeze-and-Excitation residual inception and long short-term memory(LSTM) networks for predicting protein intrinsic disorder with input from evolutionary information and predicted one-dimensional structural properties. The method, called SPOT-Disorder2, offers substantial and consistent improvement not only over our previous technique based on LSTM networks alone,but also over other state-of-the-art techniques in three independent tests with different ratios of disordered to ordered amino acid residues, and for sequences with either rich or limited evolutionary information. More importantly, semi-disordered regions predicted in SPOT-Disorder2 are more accurate in identifying molecular recognition features(MoRFs) than methods directly designed for MoRFs prediction. SPOT-Disorder2 is available as a web server and as a standalone program at https://***/server/spot-disorder2/.

关键词： Intrinsic disorder Molecular recognition feature Machine learning Deep learning Protein structure

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Treatment of long-bone nonunions

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中华创伤骨科杂志 2011年第4期13卷 366-370页

作者： Beate P hanson From AO Publishing Switzerland Clavadelerstrasse CH-7270 Davos Platz

Summary Results from four randomized controlled trials （class of evidence （CoE 11） suggest that the addition of rhBMP to fixation in long-bone nonunion neither impeded nor facilitated fracture union compared with f... 详细信息

关键词：摘要编辑部编辑工作读者

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A Myosin XI Tail Domain Homologous to the Yeast Myosin Vacuole-Binding Domain Interacts with Plastids and Stromules in Nicotiana benthamiana

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Molecular Plant 2009年第6期2卷 1351-1358页

作者： Amir Sattarzadeh Johanna Krahmer Arnaud D. Germain Maureen R. hanson Department of Molecular Biology and Genetics Biotechnology Building Cornell University Ithaca NY 14853 USA

The actin cytoskeleton plays a role in mobility of many different organelles in plant cells, including chloroplasts, mitochondria, Golgi, and peroxisomes. While progress has been made in identifying the myosin motors involved in trafficking of various plant organelles, not all of the cargoes mobilized by different members of the myosin XI family have yet been identified. The involvement of myosins in chloroplast positioning and mitochondrial movement was demonstrated by expression of a virus-induced gene silencing （VIGS） construct in tobacco. When VIGS with two different conserved sequences from a myosin Xl motor was performed in plants with either GFP-labeled plastids or mitochondria, chloroplast positioning in the dark was abnormal, and mitochondrial movement ceased. Because these and prior obser- vations have implicated a role for myosins and the actin cytoskeleton in plastid and stromule movement, we searched for myosin tail domains that could associate with plastids and stromules. While a yellow fluorescent protein （YFP） fusion with the entire tail region of myosin XI-F was usually found only in the cytoplasm, we observed that an Arabidopsis or Nicotiana benthamiana YFP：：myosin XI-F tail domain homologous to the yeast myo2p vacuole-binding domain associated with plastids and stromules after transient expression in N. benthamiana. Taken together, these observations implicate myosin motor proteins in dynamics of plastids and stromules.

关键词： Chloroplast biology cytoskeleton dynamics mitochondria gene silencing fluorescent protein.

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Catastrophe Theory Models for Stress-dependent Behaviour in a NiTi Shape Memory Alloy

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Journal of Materials Science & Technology 1994年第1期10卷 31-33页

作者： Bruce Friedman(Sunrise Enterprises, 1023 hanson Street, Annapolis, Maryland 21403, USA) Sunrise Enterprises Annapolis United States

The measurements by Huibin XU et al of the stress-dependence ot hysteresis in a NiTi shape memo ry alloy are modeled by catastrophe theory. The cusp catastrophe is used with the strain as the behaviour variable and the control parameters being functions of the stress and the temperature. A two constant model is found to be preferred to a four constant model.

关键词： NiTi Catastrophe Theory Models for Stress-dependent Behaviour in a NiTi Shape Memory Alloy

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