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A New Method of Moving Asymptotes for Large-scale Linearly Equality-constrained Minimization

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Acta Mathematicae Applicatae Sinica 2011年第2期27卷 317-328页

作者： hai-jun wang Qin Ni Hao Liu College of Sciences China University of Mining and Technology Xuzhou 221008 China College of Sciences Nanjing University of Aeronautics and Astronautics Nanjing 210016 China College of Sciences Nanjing University of Technology Nanjing 210019 China

A new method of moving asymptotes for large-scale minimization subject to linear equality constraints is discussed. In this method, linear equality constraints are deleted with null space technique and the descending direction is obtained by solving a convex separable subproblem of moving asymptotes in each iteration. New rules for controlling the asymptotes parameters are designed and the global convergence of the method under some reasonable conditions is established and proved. The numerical results show that the new method may be capable of processing some large scale problems.

关键词： method of moving asymptotes trust region linear search large scale linear equality constraints

A Unified Theoretical Treatment on Statistical Properties of the Semi-batch Self-condensing Vinyl Polymerization System

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Chinese Journal of Polymer Science 2021年第11期39卷 1510-1520页

作者： Fang Gu Jiang-Tao Li Xiao-Zhong Hong hai-jun wang College of Chemistry and Environment Science Hebei UniversityBaoding 071002China College of Physical Science and Technology Hebei UniversityBaoding 071002China Chemical Biology Key Laboratory of Hebei Province Hebei UniversityBaoding 071002China Key Laboratory of Medicinal Chemistry and Molecular Diagnosis Ministry of EducationHebei UniversityBaoding 071002China

We present a novel generating function(GF)method for the self-condensing vinyl polymerization(SCVP)system with any initial distribution of preexisted *** a method was proven to be especially useful to investigate the semi-batch SCVP system allowing a sequence of feeding operations during the ***,the number-,weight-,and z-average molecular weights as well as dispersity index of hyperbranched polymers can be explicitly given,which are determined by predetermined feeding details and conversions in each polymerization *** analytical results are further confirmed by the corresponding Monte Carlo ***,the present GF method has provided a unified treatment to the semi-batch SCVP ***,hyperbranched polymers with desired properties can be prepared by designing feeding details and presetting conversions at each step based on the present GF method.

关键词： Self-condensing vinyl polymerization Semi-batch Generating function Statistical properties

Optimal sensor placement in hydropower house based on improved triaxial effective independence method

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Water Science and Engineering 2012年第3期5卷 329-339页

作者： Ji-jian LIAN Long-jun HE hai-jun wang State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin University Tianjin 300072 P. R. China

The capacity and size of hydro-generator units are increasing with the rapid development of hydroelectric enterprises, and the vibration of the powerhouse structure has increasingly become a major problem. Field testing is an important method for research on dynamic identification and vibration mechanisms. Research on optimal sensor placement has become a very important topic due to the need to obtain effective testing information from limited test resources. To overcome inadequacies of the present methods, this paper puts forward the triaxial effective independence driving-point residue （EfI3-DPR3） method for optimal sensor placement. The Efl3-DPR3 method can incorporate both the maximum triaxial modal kinetic energy and linear independence of the triaxial target modes at the selected nodes. It was applied to the optimal placement oftriaxial sensors for vibration testing in a hydropower house, and satisfactory results were obtained. This method can provide some guidance for optimal placement of triaxial sensors of underground powerhouses.

关键词： triaxial sensor " optimal placement " Efl3-DPR3 method " hydropower house "vibration testing

Sphingosine 1 phosphate receptor-1 （S1PR1） signaling protects cardiac function by inhibiting cardiomyocyte autophagy

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Journal of Geriatric Cardiology 2018年第5期15卷 334-345页

作者： Yong-Zeng CHEN Fan wang hai-jun wang Hong-Bin LIU Department of Geriatric Cardiology Chinese People's Liberation Army General Hospital Beijing China

Objective To investigate the role of sphingosine-l-phosphate （S1P） and its receptors in cardiomyocyte autophagy, cardiomyocyte hypertrophy and cardiac function. Methods Cardiomyocytes were isolated from neonatal Vista rats. Autophagy and hypertrophy of car- diomyocytes were induced via starvation culture and phenylephrine （PE）, respectively, and S 1 P was used to treat the cardiomyocytes. The effect of S1P on cardiomyocyte autophagy was evaluated by the number of autophagosomes, the expression of autophagy-related proteins and autophagic marker genes in cardiomyocytes. The effect of S1P on cardiomyocyte hypertrophy was evaluated by examining the surface area of cardiomyoeytes and the expression of hypertrophic genes. Subsequently, different small interfering RNAs （siRNAs） were used to knockdown the expression of the three types of S 1P receptors on cardiomyocytes and to analyze the type of receptor that mediates S 1P sig- naling in cardiomyocytes. Finally, sphingosine 1 phosphate receptor-1 （S1PR1） was knockout in the mouse cardiomyocytes using the Cas9 technique. The effect of S 1PR1 on cardiac autophagy and cardiac hypertrophy was examined by assessing cardiomyocyte autophagy, car- diomyocyte hypertrophy and cardiac function. Results Starvation-induced cardiomyocyte autophagy and PE -induced cardiomyocyte hy- pertrophy were significantly attenuated by SIP. The results showed that the formation of autophagosomes was decreased, the auto- phagy-associated protein LC3 II/I and the expression of autophagic marker genes Atg5, Atgl2, Beclinl and LC3B decreased after SIP treatment. The surface area of the cardiomyocytes was decreased, and the expression of hypertrophic genes, including atrial natriuretic factor （ANF）, skeletal muscle and cardiac actin （SKA）, myosin heavy chain （β-MHC） and brain natriuretic peptide （BNP） were all decreased after S 1 P treatment. The autophagy and hypertrophy of cardiomyocytes in the S 1PR 1 knocked-down group were significantly increased c

关键词： Autophagy Cardiomyocyte Hypertrophy S1PR1

Phase Equilibria of Hydrogen Bonding Fluid in a Slit Pore with Broken Symmetry

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Chinese Journal of Chemical Physics 2015年第3期28卷 288-294,I0001页

作者： Xiao-yu Liu Jiang-tao Li Fang Gu hai-jun wang College of Chemistry and Environmental Science Hebei University Baoding 071002 China Chemical Biology Key Laboratory of Hebei Province Hebei University Baoding 071002 China Key Laboratory of Medical Chemistry and Molecular Diagnosis Ministry of Education BaodinE 071002 China

Phase equilibria of hydrogen bonding （HB） fluid confined in a slit pore with broken symmetry were investigated by the density functional theory incorporated with modified fundamental measure theory, where the symmetry breaking originated from the distinct interactions between fluid molecules and two walls of the slit pore. In terms of adsorption-desorption isotherms and the corresponding grand potentials, phase diagrams of HB fluid under various conditions are presented. Furthermore, through phase coexistences of laying transition and capillary condensation, the effects of HB interaction, pore width, fluid-pore interaction and the broken symmetry on the phase equilibrium properties are addressed. It is shown that these factors can give rise to apparent influences on the phase equilibria of confined HB fluid because of the competition between intermolecular interaction and fluid-pore interaction. Interestingly, a significant influence of broken symmetry of the slit pore is found, and thus the symmetry breaking can provide a new way to regulate the phase behavior of various confined fluids.

关键词： Hydrogen bonding fluid Broken symmetry Phase equilibria Density functional theory

Pressure Oscillating Flow in Corrugated Parallel Channel

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Communications in Theoretical Physics 2016年第12期65卷 694-700页

作者： Yu-Fei Wei hai-jun wang Yong-jun Jian Department of Physiology Hetao College Bayannur 015000 China Mathematical Science College Inner Mongolia Normal University Hohhot 010022 China School of Mathematical Sciences Inner Mongolia University Hohhot 010021 China

The approximate analytical solution of velocity is presented for incompressible and viscous fluid driven by the oscillation of the periodic pressure, between two slit parallel plates with corrugated walls by employing perturbation method. The corrugations of the two walls are described as periodic sinusoidal waves with small amplitude either in phase or half-period out of phase. Based on the analysis, we discuss the influence of the dimensionless parameters on velocity u±and mean velocity parameter φ±numerically, such as Reynolds number Re, nondimensional amplitude A of pressure gradient and wave number k.

关键词： corrugated walls perturbation method oscillating pressure

Texture and inhibitor features of grain-oriented pure iron produced by different cold-rolling processes

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Journal of Iron and Steel Research International 2018年第10期25卷 1026-1032页

作者： Jian-jun Deng hai-jun wang Zhe Rong Li Xiang Sheng-tao Qiu Yong Gan National Engineering Research Center of Continuous Casting Technology Central Iron and Steel Research Institute Beijing 100081 China Wuyang Iron and Steel Co. Ltd. Hebei Iron and Steel Group Wuyang 462400 Hebei China School of Metallurgical Engineering Anhui University of Technology Ma'anshan 243032 Anhui China

To promote the manufacture of grain-oriented pure iron, the texture and inhibitor features of two samples A and B produced by different cold-rolling processes were studied by optical microscopy, X-ray diffraction, and transmission electron microscopy. The results showed that a higher content of inhibitor elements directly resulted in a greater number of fine inhibitors, which exhibited strong inhibitory ability, leading to more fine precipitates of appropriate size effectively inhibiting the growth of primary grains in decarburized bands （sheets） during the single-stage cold-rolling process. The formation of the component with { 110}〈001〉 Goss orientation was greatly suppressed in the stage of primary recrystallization, and this component could hardly be observed in the decarburized band; by contrast, the {411 }〈148〉-oriented grains grew. During the process of high-temperature annealing, abnormal growth occurred and secondary recrystallized grains （Goss orientation） merged with other matrix grains such as { 111 }〈112〉 and {411 }〈148〉. The magnetic induction of samples A and B at 800 Aim was 1.939 T and 1.996 T, respectively.

关键词： Grain-oriented pure iron Microstructure Texture Inhibitor Cold rolling

Association of the Common Genetic Variant Upstream of INSIG2 Gene with Obesity Related Phenotypes in Chinese Children and Adolescents

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Biomedical and Environmental Sciences 2008年第6期21卷 528-536页

作者： hai-jun wang HENG ZHANG SHI-WEI ZHANG YONG-PING PAN jun MA Department of Maternal and Child Health School of Public Health Peking University Beijing 100191 China Institute of Child and Adolescent Health Peking University Beijing 100191 China Key Laboratory of Epidemiology Ministry of Education China Dongcheng School Health Care Institute Beijing 100005 China

Objective To study the association between the rs7566605 variant of INSIG2 and obesity-related phenotypes in Chinese children and adolescents. Methods The study sample consisted of two independent cohorts of Chinese children and adolescents. Anthropometric indices, lipids, blood pressure, fasting glucose, insulin and percentage of fat mass were determined. PCR with restriction fragment length polymorphism analysis was performed for genotyping the rs7566605 variant. Results In each of the two independent cohorts, no significant association was observed between rs7566605 and obesity under additive, dominant or recessive model. We also did not detect any difference in the genotype frequency between all the obese children and controls. Furthermore, we did not find evidence of an association between body composition indices and metabolic phenotypes in all children. However, the triglyceride level of CC homozygotes was significantly higher than that of GG＋GC genotypes in obese children （P=0.022）. Additionally, we observed a non-significant trend of severe obesity in a post-hoc test. Conclusion INSIG2 rs7566605 variant is not associated Chinese childhood obesity in two independent cohorts. Further study is needed to verify the effect of rs7566605 on triglyceride in obese children.

关键词： INSIG2 gene Obesity-related phenotypes Children and adolescents

Effect of Nitrogen Content on Primary Recrystallization Behavior and Magnetic Property of Hi-B Steel

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Journal of Iron and Steel Research International 2016年第10期23卷 1080-1085页

作者： hai-jun wang Bing FU Li XIANG Zhe RONG Sheng-tao QIU National Engineering Research Center of Continuous Casting Technology Central Iron and Steel Research Institute School of Metallurgical and Ecological Engineering University of Science and Technology Beijing

The effect of nitrogen content on primary recrystallization microstructure,texture and magnetic property of Hi-B steel was studied by means of optical microscopy（OM）,scanning electron microscopy（SEM）,and electron backscatter diffraction（EBSD）.When nitrogen content increased gradually from 0.005 5% to 0.031 0%,the primary grain size and variation coefficient of nitrided sheet reduced from 26.85μm,0.590 to 18.87μm,0.525-0.565,***,the primary recrystallization texture style of nitrided sheet was nearly identical to the texture style of decarburized sheet before nitriding treatment,but exhibiting a certain change on texture *** variation of average magnetic induction value（B8）and core loss value（P17/50）were manifested to be Mshaped and W-shaped curves,*** nitrogen content reached 0.016 0%,the best value of the average magnetic property of the final product was obtained as follows：the B8 and P17/50 were 1.921 Tand 0.968W/kg,***,the best performance,B8 and P17/50,of single sheet was 1.964 Tand 0.854 W/kg.

关键词： nitriding decarburization primary recrystallization magnelic property texture Hi-B steel