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Temperature Measurement of Supercooled Droplet in Icing Phenomenon by means of Dual-luminescent Imaging

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Journal of Thermal Science 2017年第4期26卷 316-320页

作者： M.Tanaka K.Morita h.Mamori N.fukushima M.Yamamoto Department of Mechanical Engineering Tokyo University of Science6-3-1 NiijukuKatushika-kuTokyo125-8585Japan Japan Aerospace Exploration Agency 7-44-1 Jindaiji Higashi-machiChofuTokyo182-8522Japan

The collision of a supercooled water droplet with a surface result an object creates ice accretion on the surface. The icing problem in any cold environments leads to severe damages on aircrafts, and a lot of studies on prevention and prediction techniques for icing have been conducted so far. Therefore, it is very important to know the detail of freezing mechanism of supercooled water droplets to improve the anti-and de-icing devices and icing simulation codes. The icing mechanism of a single supercooled water droplet impacting on an object surface would give us great insights for the purpose. In the present study, we develop a dual-luminescent imaging technique to measure the time-resolved temperature of a supercooled water droplet impacting on the surface under different temperature conditions. We apply this technique to measure the exact temperature of a water droplet, and to discuss the detail of the freezing process.

关键词： Icing Supercooled water droplet Temperature measurement Dual-luminescent imaging

Specific targeting of lung ILC2s via NRP1 in pulmonary fibrosis

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Cellular & Molecular Immunology 2022年第8期19卷 869-871页

作者： Takuro Nii Kiyoharu fukushima hiroshi Kida Department of Respiratory Medicine National Hospital Organization Osaka Toneyama Medical Center5-1-1 ToneyamaOsakaJapan Department of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine2-2 YamadaokaSuitaOsakaJapan Laboratory of host Defense World Premier Institute Immunology Frontier Research Center(WPI-IFReC)Osaka University3-1 YamadaokaSuitaOsakaJapan Department of host Defense Research Institute for Microbial Diseases(RIMD)Osaka UniversityOsaka565-0871Japan Global Center for Medical Engineering and Informatics 2-2 YamadaokaSuitaOsakaJapan

Innate lymphoid cells are predominantly tissue-resident immune cells that have diverse functions similar to T-cell subsets and regulate tissue homeostasis and innate immunity without specific antigen recognition. Prev... 详细信息

关键词： ILC2s immunity homeostasis

Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins

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World Journal of Gastroenterology 2006年第19期12卷 3031-3037页

作者： Kazuhiro fukushima Yoko Aoi Shinichi Kato Koji Takeuchi Department of Pharmacology and Experimental Therapeutics Kyoto Pharmaceutical University MisasagiYamashinaKyoto 607-8414Japan

AIM： Lafutidine, a histamine h2 receptor antagonist, exhibits gastro-protective action mediated by capsaicinsensitive afferent neurons （CSN）. We compared the effect between lafutidine and capsaicin, with respect to the interaction with endogenous prostaglandins （PG）, nitric oxide （NO） and the afferent neurons, including transient receptor potential vanilloid subtype 1 （TRPV1）. METhODS： Male SD rats and C57BL/6 mice, both wildtype and prostacyclin IP receptor knockout animals, were used after 18 h of fasting. Gastric lesions were induced by the po administration of hCl/ethanol （60% in 150 mmol/L hCl） in a volume of 1 mL for rats or 0.3 mL for mice. RESULTS： Both lafutidine and capsaicin （1-10 mg/kg, po） afforded dose-dependent protection against hCI/ ethanol in rats and mice. The effects were attenuated by both the ablation of CSN and pretreatment with NG-nitro- L-arginine methyl ester, yet only the effect of capsaicin was mitigated by prior administration of capsazepine, the TRPV1 antagonist, as well as indomethacin. Lafutidine protected the stomach against hCl/ethanol in IP receptor knockout mice, similar to wild-type animals, while capsaicin failed to afford protection in the animals lacking IP receptors. Neither of these agents affected the mucosal PGE2 or 6-keto PGF1α contents in rat stomachs. Capsaicin evoked an increase in [Ca^2＋]i in rat TRPV1-transfected hEK293 cells while lafutidine did not. CONCLUSION： These results suggest that although both lafutidine and capsaicin exhibit gastro-protective action mediated by CSN, the mode of their effects differs regarding the dependency on endogenous PGs/IP receptors and TRPV1. It is assumed that lafutidine interacts with CSN at yet unidentified sites other than TRPV1.

关键词： Lafutidine A histamine h2-receptor antagonist Gastric protection Prostaglandin Capsaicin-sensirive afferent neuron TRPVt

Invariant natural killer T cells and iron metabolism orchestrate skin development and homeostasis

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Cellular & Molecular Immunology 2023年第10期20卷 1095-1097页

作者： hiroshi Nabeshima Takayuki Niitsu Kiyoharu fukushima hiroshi Kida Laboratory of host Defense World Premier Institute Immunology Frontier Research Center(WPI-IFReC)Osaka University3-1 YamadaokaSuitaOsakaJapan Department of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine2-2 YamadaokaSuitaOsakaJapan Department of host Defense Research Institute for Microbial Diseases(RIMD)Osaka University3-1 YamadaokaSuitaOsakaJapan Department of Respiratory Medicine National Hospital Organization Osaka Toneyama Medical Center5-1-1 ToneyamaOsakaJapan Global Center for Medical Engineering and Informatics 2-2 YamadaokaSuitaOsakaJapan

In recent years,innate-like T-cell populations,such as invariant natural killer T(iNKT)cells and mucosal-associated invariant T(MAIT)cells,have been identified[1].These cells are different from conventional T cells in that they reside in tissues such as the liver,lung,and skin,rather than the lymph node and spleen[2].Although iNKT and MAIT cells are abundant in the skin immediately after birth,the detailed functions or the mechanisms regulating their localization have not been clarified[3].In a study published in Nature Immunology,Wang et *** that the early homing of iNKT cells to the skin was dependent on CCR10 expression during the stage of thymic development and was critical for proper commensal bacterial colonization and skin development[4].

关键词： killer metabolism homeostasis

Effect of equal-channel angular pressing on pitting corrosion resistance of anodized aluminum-copper alloy

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中国有色金属学会会刊：英文版 2009年第4期19卷 904-908页

作者： In-Joon SON hiroaki NAKANO Satoshi OUE Shigeo KOBAYAShI hisaaki fukushima Zenji hORITA Department of Materials Process Engineering Graduate School of EngineeringKyushu University Department of Materials Science and Engineering Faculty of EngineeringKyushu University Department of Applied Chemistry and Biochemistry Faculty of EngineeringKyushu Sangyo University

The effect of equal-channel angular pressing(ECAP) on the pitting corrosion resistance of anodized Al-Cu alloy was investigated by electrochemical techniques in a solution containing 0.2 mol/L AlCl3 and also by surface *** was conducted for 20 min at 200 and 400 A/m2 in a solution containing 1.53 mol/L h2SO4 and 0.018 5 mol/L Al2(SO4)3·16h2O at 20 ℃.Anodized Al-Cu alloy was immediately dipped in boiling water for 20 min to seal the micro pores present in anodic oxide *** time required before initiating pitting corrosion of anodized Al-Cu alloy is longer with ECAP than without,indicating that ECAP process improves the pitting corrosion resistance of anodized Al-Cu *** phase precipitates such as Si,Al-Cu-Mg and Al-Cu-Si-Fe-Mn intermetallic compounds are present in Al-Cu alloy and the size of these precipitates is greatly decreased by application of ***-Cu-Mg intermetallic compounds are dissolved during anodization,whereas the precipitates composed of Si and Al-Cu-Si-Fe-Mn remain in anodic oxide films due to their more noble corrosion potential than ***-SEM and EPMA observation reveal that the pitting corrosion of anodized Al-Cu alloy occurs preferentially around Al-Cu-Si-Fe-Mn intermetallic compounds,since the anodic oxide films are absent at the boundary between the normal oxide films and these impurity *** improvement of pitting corrosion resistance of anodized Al-Cu alloy processed by ECAP appears to be attributed to a decrease in the size of precipitates,which act as origins of pitting corrosion.

关键词：铝铜合金抗点蚀挤压转角通道

Recurrent ventricular arrhythmia due to aconite intoxication successfully treated with landiolol:A case report

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World Journal of Clinical Cases 2023年第22期11卷 5303-5308页

作者： Chiaki Matsuo Koji Yamamoto hidetada fukushima Daisuke Yajima hiroyuki Inoue Department of Emergency and Critical Care Medicine Nara Medical UniversityKashihara City 634-8522NaraJapan Department of Forensic Medicine School of MedicineInternational University of Health and WelfareNarita City 286-8686ChibaJapan

BACKGROUND Ventricular arrhythmias,such as ventricular tachycardia and fibrillation,are the main causes of death in patients with aconite *** SUMMARY A 51-year-old man presented to our emergency department because he was vomiting after ingesting aconite root to attempt *** arrival,the patient was hemodynamically unstable,and his electrocardiogram revealed polymorphic ventricular extrasystoles and non-sustained ventricular *** was immediately administered for ventricular ***,the patient remained *** administered continuous intravenous landiolol as the ventricular arrhythmia worsened,gradually suppressing *** patient returned to sinus rhythm 16 h after arriving at the *** aconitum alkaloids act on voltage-gated Na+-channels and induce ventricular or supraventricular *** suppresses sympathetic nerve activity through its blocking effect,preventing *** Landiolol can be a therapeutic option for amiodarone-refractory ventricular arrhythmias caused by aconite intoxication.

关键词： Aconite Landiolol Amiodarone Arrhythmia Toxicology Case report

Investigating drivers of active nitrification in organic horizons of tropical forest soils

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Soil Ecology Letters 2023年第3期5卷 89-99页

作者： Shinichi Watanabe Makoto Shibata Yoshiko Kosugi Lion Marryanna Keitaro fukushima Arief hartono Shinya Funakawa Graduate School of Global Environmental Studies Kyoto UniversityKitashirakawa Oiwake-choSakyo-kuKyoto606-8502Japan Graduate School of Agriculture Kyoto UniversityKitashirakawa Oiwake-choSakyo-kuKyoto606-8502Japan Forest Research Institute Malaysia 52109 KepongSelangorMalaysia Center for Ecological Research Kyoto University509-3Hirano 2-chomeOtsu-shiShiga520-2113Japan Faculty of Agriculture Bogor Agricultural UniversityJalan MerantiKampus IPB Darmaga 16680BogorIndonesia

high nitrate leaching has been observed from the O horizons of some tropical forests;however,the drivers of high nitrate production(active nitrification)in these O horizons have not yet been *** study investigated the drivers of active nitrification in the O horizon of tropical forest soils by focusing on two of the most widely recognized controlling factors of nitrification,total N,and *** collected mineral and O horizons from eight tropical forests in Cameroon,Indonesia,and Malaysia and measured gross nitrification *** O horizons showed significantly higher gross nitrification rates than mineral horizons,indicating that these O horizons have a high potential for *** nitrification rates in the O horizons were positively correlated with both total N and ph,and the chemical properties(e.g.,total content of N,P,and base cations)were *** correlations suggested that the underlying driver of nitrification in the O horizon was nutrient richness in the *** also indicated a threshold of gross nitrification rates around ph values of 5.5–*** elucidate that active nitrification and subsequent high nitrate leaching from the O horizon could be driven by nutrient-rich litter,possibly derived from soil fertility and tree species.

关键词： nitrogen dynamics gross nitrification rate organic horizon forest floor acidic soil leguminous trees

Precise Orientational Control of Electroactive Units Using a Tripodal Triptycene Scaffold to Direct Noncovalent Pairing at the Single Molecular Level

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Precision Chemistry 2023年第6期1卷 388-394页

作者： Colin J.Martin Tomoya Fukui Ryosuke Takehara Shintaro Fujii Takanori fukushima Laboratory for Chemistry and Life Science Institute of Innovative ResearchTokyo Institute of TechnologyYokohama 226-8503Japan Department of Chemistry School of ScienceTokyo Institute of TechnologyTokyo 152-8551Japan

A break junction technique has been established to explore conductive behavior at the single molecular level,and recent interest has shifted toward the evaluation of bimolecular systems interacting through noncovalent intermolecular *** requires precise control over the orientation of the two molecules so that they can adapt an appropriate face-to-face arrangement between two ***,we present an approach using a tripodal triptycene scaffold that allows for accurate positioning of electroactive subunits with an upright configuration on substrate *** incorporated electron-donating tetrathiafulvalene or electron-accepting anthraquinone into the molecular scaffold and confirmed that the resulting molecules retain the electronic properties particular to their attached ***-assembled monolayers(SAMs)of these molecules were prepared on Au(111)and characterized by XPS and *** break junction techniques were applied to the SAMs,revealing two electrical conduction regimes;one arises from single-molecules sandwiched between two electrodes,and the second from intermolecularly interacting homodimers that bridge between *** observation demonstrates the validity of the approach of using tripodal triptycene scaffolds to precisely direct electroactive subunits to undergo intermolecular *** believe that the present work will provide a new avenue for evaluating the heterodimers at the single molecular level.

关键词： STM break junction self-assembled monolayers supramolecular scaffold noncovalent interactions triptycene

Identification of Naturally Occurring Polyamines as Root-Knot Nematode Attractants

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Molecular Plant 2020年第4期13卷 658-665页

作者： Morihiro Oota Allen Yi-Lun Tsai Dan Aoki Yasuyuki Matsushita Syuuto Toyoda Kazuhiko fukushima Kentaro Saeki Kei Toda Laetitia Perfus-Barbeoch Bruno Favery hayato Ishikawa Shinichiro Sawa Graduate School of Science and Technology Kumamoto UniversityKurokami 2-39-1Kumamoto 860-8555Japan Graduate School of Bioagricultural Sciences Nagoya UniversityNagoya 464-8601Japan INRA Universite Cote d'AzurCNRSUMR 1355-7254 Institut Sophia AgrobiotechSophia-Antipolis 06900France Present address:Dormancy and Adaptation Research Unit RIKEN Center for Sustainable Resource ScienceYokohama 230-0045Japan

Root-knot nematodes(RKNs;genus Meloidogyne)are a class of plant parasites that infect the roots of many plant *** is believed that RKNs target certain signaling molecules derived from plants to locate their hosts;however,currently,no plant compound has been unambiguously identified as a universal RKN *** address this question,we screened a chemical library of synthetic compounds for Meloidogyne incognita *** breakdown product of aminopropylam ino-anthraquinone,1,3-diam inopropane,as well as its related compounds,putrescine and cadaverine,were found to attract *** exam ining various polyamines,*** were found to be attracted specifically by natural com pounds that possess three to five methylene groups between two terminal amino *** cryo-TO F-SIM S/SEM,cadaverine was indeed detected in soybean root cortex cells and the surrounding rhizosphere,establishing a chemical *** addition to cadaverine,putrescine and 1,3-diam inopropane were also detected in root exudate by hPLC-MS/*** ore,exogenously applied cadaverine is sufficient to enhance *** infection of Arabidopsis *** results suggest that *** is likely attracted by polyam ines to locate the appropriate host plants,and the naturally occurring polyamines have potential applications in agriculture in developing protection strategies for crops from RKN infection.

关键词： plant-parasitic nematode chemotaxis rhizosphere organic diamine