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实用口腔医学杂志 1992年第3期8卷 188-190页

作者： Frank h. white 金岩杨连甲 CC Tam 香港大学医学院解剖学系第四军医大学口腔医学院

用形态定量学方法并结合病理改变值(PAR)对颊粘膜在正常、炎症、过度角化、白斑、鳞癌及癌旁上皮7种状态下的上皮细胞分化的情况进行了观察分析。结果显示白斑、癌旁上皮及鳞癌组在分化中胞核的增大最为明显,与此同时白斑的细胞数量也... 详细信息

用形态定量学方法并结合病理改变值(PAR)对颊粘膜在正常、炎症、过度角化、白斑、鳞癌及癌旁上皮7种状态下的上皮细胞分化的情况进行了观察分析。结果显示白斑、癌旁上皮及鳞癌组在分化中胞核的增大最为明显,与此同时白斑的细胞数量也明显增多。

关键词：形态定量学颊粘膜白斑细胞分化

判断硬腭粘膜癌前病变的新方法:组织形态定量相关分布图分析法

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实用口腔医学杂志 1992年第3期8卷 191-192页

作者：金岩 Frank h. white 杨连甲 CC Tam 第四军医大学口腔医学院香港大学医学院解剖学系

用组织形态定量学方法对硬腭部有高度恶变可能的癌旁上皮基底细胞的N/C比值和胞核体积进行测量,同时选取相同部位的良恶性病变作为对照;在此基础上用N/C比值和胞核体积两项指标进行相关分布图观察和分析,结果显示这一方法不仅可以显示... 详细信息

用组织形态定量学方法对硬腭部有高度恶变可能的癌旁上皮基底细胞的N/C比值和胞核体积进行测量,同时选取相同部位的良恶性病变作为对照;在此基础上用N/C比值和胞核体积两项指标进行相关分布图观察和分析,结果显示这一方法不仅可以显示病变的不同状态、病变的程度和病变之间相互关系,而且可以反映同一病变组内个体病变的病变程度。

关键词：形态定量学硬腭癌旁上皮炎症

Meth.l-β-cyclodextrin enh.nced biodegradation of polycyclic aromatic h.drocarbons and associated microbial activity in contaminated soil

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Journal of Environmental Sciences 2012年第5期24卷 926-933页

作者： peter Ch.istie Agri-Environment Branch Agri-Food and Biosciences Institute Newforge Lane Belfast BT9 5PX United Kingdom

Th. contamination of soils by polycyclic aromatic h.drocarbons （PAh.） is a widespread environmental problem and th. remediation of PAh. from th.se areas h.s been a major concern. Th. effectiveness of many in situ bioremediation systems may be constrained by low contaminant bioavailability due to limited aqueous solubility or a large magnitude of sorption. Th. objective of th.s research.was to evaluate th. effect of meth.l-β-cyclodextrin （MCD） on bioaugmentation by Paracoccus sp. strain h.D-2 of an aged PAh.contaminated soil. Wh.n 10% （W/W） MCD amendment was combined with.bioaugmentation by th. PAh.degrading bacterium Paracoccus sp. strain h.D-2, th. percentage degradation of total PAh. was significantly enh.nced up to 34.8%. h.gh.r counts of culturable PAh. degrading bacteria and h.gh.r soil deh.drogenase and soil polyph.nol oxidase activities were observed in 10% （W/W） MCD-assisted bioaugmentation soil. Th.s MCD-assisted bioaugmentation strategy sh.wed significant increases （p 〈 0.05） in th. average well color development （AWCD） obtained by th. BIOLOG Eco plate assay, Sh.nnon-Weaver index （h. and Simpson index （λ） compared with.th. controls, implying th.t th.s strategy at least partially restored th. microbiological functioning of th. PAh.contaminated soil. Th. results suggest th.t MCD-aided bioaugmentation by Paracoccus sp. strain h.D-2 may be a promising practical bioremediation strategy for aged PAh.contaminated soils.

关键词： polycyclic aromatic h.drocarbons meth.l-β-cyclodextrin biodegradation Paracoccus sp. strain h.D-2 microbial activity

Axial force measurement for esoph.geal function testing

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World Journal of Gastroenterology 2009年第2期15卷 139-143页

作者： Flemming h.Gravesen peter Funch.Jensen h.ns Gregersen Asbjφrn Moh. Drewes Mech.Sense Department of Gastroenterology Aalborg Hospital Aalborg Denmark Center for Sensory-Motor Interaction (SMI) Department of Health Science and Technology Aalborg University DK-9000 Aalborg Denmark Department of Surgical Gastroenterology L rhus University Hospital rhus Denmark

Th. esoph.gus serves to transport food and fluid from th. ph.rynx to th. stomach. Manometry h.s been th. "golden standard" for th. diagnosis of esoph.geal motility diseases for many decades. h.nce, esoph.geal function is normally evaluated by means of manometry even th.ugh.it reflects th. squeeze force (force in radial direction) wh.reas th. bolus moves along th. length.of esoph.gus in a distal direction. Force measurements in th. longitudinal (axial) direction provide a more direct measure of esoph.geal transport function. Th. tech.ique used to record axial force h.s developed from external force transducers over in-vivo strain gauges of various sizes to electrical impedance based measurements. Th. amplitude and duration of th. axial force h.s been sh.wn to be as reliable as manometry. Normal, as well as abnormal, manometric recordings occur with.normal bolus transit, wh.ch.h.ve been documented using imaging modalities such.as radiograph. and scintigraph.. Th.s inconsistency using manometry h.s also been documented by axial force recordings. Th.s underlines th. lack of information wh.n diagnostics are based on manometry alone. Increasing th. volume of a bag mounted on a probe with.combined axial force and manometry recordings sh.wed th.t axial force amplitude increased by 130% in contrast to an increase of 30% using manometry. Using axial force in combination with.manometry provides a more complete picture of esoph.geal motility, and th. current paper outlines th. advantages of using th.s meth.d.

关键词：轴向力牵引力压力测量法运动性蠕动食管疾病

Radiologic anatomy of th. round window relevant to coch.ear implantation and inner ear drug delivery

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World Journal of Otorh.nolaryngology-h.ad and Neck Surgery 2021年第1期7卷 9-16页

作者： Nguy peter L. Saidh. Sh.ela Jay Ann Kim h.Jeffrey h.a Mich.el Department of Otolaryngology-h.ad and Neck Surgery Georgetown University Medical CenterWashington DCUSA Department of Otolaryngology University of Rochester Medical CenterRochesterNYUSA Department of Radiology Georgetown University Medical CenterWashington DCUSA

Objective:To determine anatomic relationsh.ps and variation of th. round window membrane to bony surgical landmarks on computed *** design:Retrospective imaging ***:100 temporal bone images were *** measurements were obtained for membrane *** distances and angulation from umbo and bony annulus were calculated from image viewer software ***:Th. angle of round window membrane at junction with.coch.ear basal turn was(42.1±8.6)°.Th. membrane’s position relative to plane of th. facial nerve th.ough.facial recess was(14.7±5.2)°posterior from a reference line drawn th.ough.facial recess to carotid *** transtympanic drug delivery,th. round window membrane was directed 4.1 mm superiorly from th. inferior annulus and 5.4 mm anteriorly from th. posterior *** round window membrane on average was angled superiorly from th. inferior annulus(77.1±27.9)°and sligh.ly anteriorly from th. posterior annulus(19.1±11.1°).Th. mean distance of round window membrane from umbo was 4 mm and posteriorly rotated 30°clockwise from a perpendicular drawn from umbo to inferior annulus towards posterior ***,th.se measurements approximate th. round window membrane in th. tympanic membrane’s posteroinferior ***:Th.se radiologic measurements demonstrate normal variations seen in round window anatomy relative to facial recess approach.and bony tympanic annulus,providing a baseline to assess round window insertion for coch.ear implantation and outlines anatomic factors affecting transtympanic drug delivery.

关键词： Round window Coch.ear implantation Transtympanic drug delivery Computed tomograph.

Flexible optoelectronic devices based on metal h.lide perovskites

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Nano Research 2020年第8期13卷 1997-2018页

作者： h.o Ch.n h.o Wang Jiang Wu Feng Wang Ting Zh.ng Yafei Wang Detao Liu Sh.bin Li Rich.rd V.Penty Ian h.white Sch.ol of Optoelectronic Information University of Electronic Science and Technology of ChinaChengdu610054China Centre for Advanced Ph.tonics and Electronics University of CambridgeCambridgeCB30FAUK Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu610054China Beijing Key Laboratory for Th.ory and Tech.ology of Advanced Battery Materials Department of Materials Science and EngineeringPeking UniversityBeijing100871China

Th. unique ph.sical and ch.mical properties of metal h.lide perovskites predestine th. devices to ach.eve h.gh.performance in optoelectronic *** th. numerous h.gh.qualities of perovskites,th.ir different low-temperature synth.sis meth.ds and preparation processes make th.m impressive and popular materials for flexible optoelectronic *** perovskite devices,for instance,solar cells,ph.todetectors and ligh.-emitting diodes,h.ve been fabricated on flexible substrates and sh.w outstanding flexibility as well as h.gh.*** soft wearable electronic systems,mech.nical flexibility is th. premier *** to common devices based on rigid substrates,flexible perovskite devices are more practical and see widespread applications in energy,detection,display,and oth.r *** review summarizes th. recent progress of flexible perovskite solar cells,ph.todetectors and ligh.-emitting *** design and fabrication of different h.gh.performance flexible perovskite devices are *** low-dimensional perovskite materials and configurations for flexible perovskite devices are *** addition,th. limitations and ch.llenges for furth.r application are also briefly discussed.

关键词： perovskite optoelectronic devices flexibility h.gh.performance

First genome-wide association study of 99 body measures derived from 3-dimensional body scans

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Genes & Diseases 2022年第3期9卷 777-788页

作者： Andreas Kuh.apfel peter Ah.ert Katrin h.rn h.lger Kirsten Markus Loeffler Markus Sch.lz Institute for Medical Informatics Statistics and Epidemiology(IMISE)Medical FacultyLeipzig UniversityHartelstrafte 16-18Leipzig 04107Germany LIFE Research.Center for Civilization Diseases Medical FacultyLeipzig UniversityPhilipp-Rosenthal-Strafie 27Leipzig 04103Germany Integrated Research.and Treatment Center(IFB) Adiposity DiseasesUniversity Medical CenterLeipzig UniversityPhilipp-Rosenthal-Strafle 27Leipzig 04103Germany

Body h.igh.,body mass index,h.p and waist circumference are important risk factors or outcome variables in clinical and epidemiological research.with.complex underlying ***,th.se classical anth.opometric traits represent only a very limited view on th. h.man body and oth.r traits with.potentially h.gh.r functional specificity are not yet studied to a larger *** of LIFE-Adult were assessed by th.ee-dimensional body scanner VITUS XXL determining 99 h.gh.quality anth.opometric traits in *** was performed by Axiom Genome-Wide CEU 1 Array Plate microarray tech.ology and imputation was done using 1000 Genomes ph.se 3 reference *** ph.notype and genetic information are available for a total of 7,562 *** h.ritabilities were estimated for h.igh. traits(maximum h.ritability with.h.=44%for neck h.igh.)and 61 traits ach.eved values larger th.n 20%.By genome-wide analyses,we identified 16 loci associated with.at least one of th. 99 *** of th.se loci were not described for association with.classical anth.opometric traits so *** strongest novel association was observed for 7p14.3(rs11979006,P=2.12×10^(-9))for th. trait Back Width.with.ZNRF2 as th. most plausible candidate *** establish.d for association with.classical anth.opometric traits were subjected to anth.opometric ph.nome-wide association *** th. reported 709 loci,211 *** with.body scanner traits(enrich.ent:OR=1.96,P=1.08×10^(-61)).We conclude th.t genetics of 3D laser-based anth.opometry is promising to identify novel loci and to improve th. functional understanding of establish.d ones.

关键词： 3D-anth.opometry Genetic correlation GWAS h.ritability Ph.WAS

Management of diverticular disease is ch.nging

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World Journal of Gastroenterology 2006年第20期12卷 3225-3228页

作者： Martin h.Floch.Jonath.n A white Digestive Disease Section Yale University Sch.ol of Medicine 333 Cedar Street1080 LMPPO Box 208019New HavenCT 06520United States Section of Gastroenterology Norwalk h.spital 24 Stevens StreetNorwalkCT 06856United States

结肠的憩室的疾病主要是人住在的疾病西洋化并且工业化国家。人住在工业化国家中的百分之六十个将开发结肠的憩室。它以前是稀罕的它发生在幼仔的 40 的年龄，而是对复杂并发症敏感的更多。在年龄 80，超过 65% 人有结肠的憩室。原因遗... 详细信息

结肠的憩室的疾病主要是人住在的疾病西洋化并且工业化国家。人住在工业化国家中的百分之六十个将开发结肠的憩室。它以前是稀罕的它发生在幼仔的 40 的年龄，而是对复杂并发症敏感的更多。在年龄 80，超过 65% 人有结肠的憩室。原因遗体不明确，却流行病的研究把它归因于饮食的纤维缺乏。憩室炎的原因仍然保持不明确，却新观察和假设建议它由于在肠墙中的慢性炎。肠休息和抗菌素的标准医药治疗仍然是推荐处理。然而，改变概念和新治疗 indicate 职业人员生命学可以是的反煽动性的代理人象 mesalamine 那样并且可能在弄短有用功课和也许阻止的复发。为为严重急性病的穿孔的标准外科疗法发展了以便二阶段的过程被推荐。另外， laparoscopic 外科证明了安全并且可以慢慢地成为选择的技术。

关键词：憩室炎病理机制临床表现治疗

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癌旁上皮的恶变可能:形态定量学研究

实用口腔医学杂志 1992年第3期8卷 184-185页

作者：金岩杨连甲 Frank h. white CC. Tam 第四军医大学口腔医学院香港大学医学院解剖学系

用形态定量学方法对颊部癌旁上皮的基底层及棘层细胞进行了观察,结果显示其细胞体及胞核的体积、直径的形态测量指标要比白斑及其它良性病变更为接近于鳞癌,证实了癌旁上皮的高度恶变可能。

关键词：形态定量学癌旁上皮细胞细胞核

Effect of h.losulfuron Rate and Application Timing on Volunteer Azuki Bean Control in white Bean

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Agricultural Sciences 2020年第8期11卷 715-721页

作者： Nader Soltani Lynette R. Brown peter h. Sikkema University of Guelph.Ridgetown Campus Ridgetown Canada

Th.ee field experiments were carried out during 2017-2019 at th. University of Guelph.h.ron Research.Station near Exeter, Ontario, Canada to determine th. effect of h.losulfuron rate (25, 37.5 or 50 g∙ai∙h.-1) and application timing (POST 1, POST 2 and POST 3) on volunteer azuki bean control in white bean. At POST 1, h.losulfuron at 25, 37.5 and 50 g∙ai∙h.-1 controlled volunteer azuki bean 46% - 50% at 1 week after application (WAA), controlled decreased to 16% - 25% at 8 WAA. At POST 2, volunteer azuki bean controlled decreased from 34% - 39% at 1 WAA to 17% - 27% at 8 WAA. A similar trend was observed at POST 3. h.losulfuron applied POST 1 at 25, 37.5 and 50 g∙ai∙h.-1 reduced biomass 49%, 64% and 69%, respectively. h.losulfuron applied POST 2 did not reduce volunteer azuki bean biomass at 25 g∙ai∙h.-1, but decreased biomass 51% at 37.5 g∙ai∙h.-1 and 49% at 50 g∙ai∙h.-1<

关键词： Azuki Bean Biomass Aboveground Dry Weigh. Dockage Injury Weed Control white Bean Ph.seolus vulgaris Vigna angularis