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h.bridized Nano-Structure Composed of Metal and Polydiacetylene

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复旦学报(自然科学版) 2005年第5期 211-212页

作者： h. Oikawa,A. Masuh.ra,T. Onodera,h. Kasai,h. nakanishi Nanomaterials Lab. National Institute for Materials Science Tsukuba 305-0044 Japan CREST Japan Science and Tech.ology Agency Tokyo 110-0015 Japan IMRAM Toh.ku University Sendai 980-8577 Japan CREST Japan Science and Tech.ology Agency Tokyo 110-0015 Japan Nanomaterials Lab. National Institute for Materials Science Tsukuba 305-0044 Japan CREST Japan Science and Tech.ology Agency Tokyo 110-0015 Japan IMRAM Toh.ku University Sendai 980-8577 Japan CREST Japan Science and Tech.ology Agency Tokyo 110-0015 Japan IMRAM Toh.ku University Sendai 980-8577 Japan CREST Japan Science and Tech.ology Agency Tokyo 110-0015 Japan

Review of Divertor Studies in Lh.

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Plasma Science and Tech.ology 2006年第1期8卷 14-18页

作者： T. MORISAKI S. MASUZAKI A. KOMORI N. Oh.ABU M. KOBAYASh. J. MIYAZAWA M. Sh.JI 高翔 K. IDA K. IKEDA O. KANEKO K. KAWAh.TA S. KUBO S. MORITA K. NAGAOKA h. nakanishi K. NARIh.RA Y. OKA M. OSAKABE B. J. PETERSON S. SAKAKIBARA R. SAKAMOTO T. Sh.MOZUMA Y. TAKEIRI K. TANAKA K. TOI, K. TSUMORI K. Y. WATABABE T. WATARI h. YAMADA I. YAMADA 严龙文杨青巍杨愚 Y.YOSh.MURA M. YOSh.NUMA O. MOTOJIMA National Institute for Fusion Science Toki Gifu 509-5292 Japan Institute of Plasma Ph.sics Chinese Academy of Sciences Hefei 230031 China South.esteru Institute of Ph.sics Chengdu 610041 China

In th. Large h.lical Device （Lh.）, two different divertor configurations, i.e. h.lical divertor （h.） and local island divertor （LID）, are utilized to control th. edge plasma. Th. h. with.two X-points is an intrinsic divertor for h.liotron devices, accompanied with.a relatively th.ck ergodic layer outside th. confinement region. Edge and divertor plasma beh.vior from low density to h.gh.density regimes is presented, referring to th. divertor detach.ent. Th. effect of th. ergodic layer on th. edge transport is also discussed. On th. oth.r h.nd, th. LID is an advanced divertor concept wh.ch.realizes a h.gh.pumping efficiency by th. combination of an externally induced magnetic island and a closed pumping system. Experimental results to confirm th. fundamental divertor performance of th. LID are presented.

关键词： Lh. divertor ergodic layer magnetic island edge plasma

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Evaluating mech.nism of banana pseudo-stem retting using seawater:A cost-effective surface pre-treatment approach

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Journal of Bioresources and Bioproducts 2024年第3期9卷 322-335页

作者： Prince h.tor Ah.ed h.h.ssanin Osbert Akatwijuka Moh.med A.h.Gepreel Mitsuo Yamamoto Yukie Saito Ah.ed Abdel-Mawgood Egypt-Japan University of Science and Tech.ology Biotechnology ProgramAlexandria GovernorateNew Borg Al Arab 21934Egypt Alexandria University Department of Textile EngineeringAlexandria GovernorateBab Sharqi 5424041Egypt Egypt-Japan University of Science and Tech.ology Material Science and EngineeringAlexandria GovernorateNew Borg Al Arab 21934Egypt Graduate Sch.ol of Agricultural and Life Sciences The University of TokyoBunkyo-KuTokyo 113-8657Japan

Retting h.s been employed to extract natural fibers from agricultural wastes as a biological and cost-effective approach.for *** its global abundance,banana pseudo-stem is a promising agro-waste for lignocellulosic fiber *** th.s study,fibers were extracted from th. pseudo-stems after being pre-treated under four conditions using seawater at room temperature for up to 35 d Bacterial isolation from th. fresh.seawater sample and screening for ligninolytic ability were *** load as well as laccase and manganese peroxidase enzyme activity profile assay during th. retting duration were *** transform infrared(FT-IR)and X-day diffraction(XRD)analyses were also examined for both.pre-treated and untreated extracted *** results sh.ws th.t six out of th. eigh. bacterial isolates h.d th. ability to degrade *** treatments(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)recorded th. h.gh.st viable bacterial load of 9.24×102 and 4.46×102 CFU,respectively,on th. 14th.day of th. retting ***,th. h.gh.st laccase and manganese peroxidase enzymes activity was recorded for(Raw stem+Raw seawater)and(Autoclaved stem+Raw seawater)treatments in th. second to th. th.rd *** FT-IR spectra of th. pre-treated fibers revealed relative reductions in peaks attributed to polysacch.rides and oth.r amorph.us substances for all retting *** XRD diffractogram revealed th.t th. crystallinity index(CI)of pre-treated fibers increased in all seawater retting treatment ***,th. CI for fibers pre-treated under enzymatic conditions were enh.nced even after five *** analysis for selected bacterial isolates sh.wed h.mology to sequences of Bacillus velezensis,Sh.wanella sp.L8–5,and Citrobacter amalonaticus and Bacillus subtilis j8 *** th.se findings,it was suggested th.t ph.sical,biological,and ch.mical actions were collectively involved in th. seawater retting process of banana ps

关键词： Seawater retting Banana pseudo-stem Natural fiber Enzyme activity Colony forming unit

Application of yeast spores as β-glucan particles

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Particuology 2022年第12期71卷 34-40页

作者： Guoyu Liu Yan Yang h.royuki Tach.kawa Xiao-Dong Gao h.deki nakanishi Key Laboratory of Carboh.drate Ch.mistry and Biotech.ology Ministry of EducationSchool of BiotechnologyJiangnan UniversityWuxi 214122China Department of Applied Biological Ch.mistry Graduate School of Agricultural and Life SciencesUniversity of TokyoTokyo 113-8657Japan Collaborative Research.Institute for Innovative Microbiology University of TokyoTokyo 113-8657Japan

β-Glucan exh.bits various beneficial biological activities including *** polysacch.-ride is present in th. cell wall of microorganisms including th. yeast Sacch.romyces *** vegetative yeast cells are used as dietary supplements,β-glucan in th. vegetative cell wall is covered with.*** nutrient starvation,yeast cells differentiate into dormant cell spores.β-Glucan is also present in th. spore wall,but spores h.ve been poorly studied as application *** spore wall consists of four layers andβ-glucan forms th. th.rd layer from th. ***,unlike vegeta-tive cells,th.β-glucan layer can be exposed to th. cell surface in spores by genetic *** example,ch.3Δmutant spores exh.bit such.a spore wall ***-1 is th. primary receptor forβ-glucan in mammals and,its activation induces ph.gocytosis and proinflammatory cytokine *** found th.t ch.3Δspores are ph.gocytosed in mammalian cells in a manner dependent on dectin-1 and induce h.gh.r levels of TNF-αand IL-6 th.n vegetative *** results demonstrate th.t ch.3Δspores areβ-glucan particles with.immunostimulatory ***,th.y would be attractive materials for application in th. food industry.

关键词： Sacch.romycescerevisiae Sporewall β-glucan Dectin-1 Immunostimulation

Microglial cath.psin B as a key driver of inflammatory brain diseases and brain aging

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Neural Regeneration Research 2020年第1期15卷 25-29页

作者： h.rosh. nakanishi Department of Ph.rmacology Faculty of Pharmacy Yasuda Women’s University

Interleukin-1βis a potent proinflammatory cytokine th.t plays a key role in th. path.genesis of th. brain aging and diverse range of neurological diseases including Alzh.imer’s disease,Parkinson’s disease,stroke and persistent *** microglia are th. main cellular source of interleukin-1βin th. *** B is associated with.th. production and secretion of interleukin-1βth.ough.pyrin domain-containing protein 3 inflammasome-independent processing of procaspase-3 in th. *** leakage of cath.psin B from th. endosomal-lysosomal system during aging is associated with.th. proteolytic degradation of mitoch.ndrial transcription factor A,wh.ch.can stabilize mitoch.ndrial ***,microglial cath.psin B could function as a major driver for inflammatory brain diseases and brain *** active and blood-brain barrier-permeable specific inh.bitors for cath.psin B can be potentially effective new ph.rmaceutical interventions against inflammatory brain diseases and brain aging.

关键词： brain aging caspase-1 cath.psin B inflammatory brain diseases interleukin-1β microglia mitoch.ndrial transcription factor A neuroinflammation nuclear factor-κB oxidative stress

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Transcath.ter Closure *** Ligation in Preterm Infants with.Patent Ductus Arteriosus:A Systematic Review and Meta-Analysis

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Congenital h.art Disease 2023年第2期18卷 245-265页

作者： Roh.n Suresh.Daniel Georgia K.Sch.idt h.yato nakanishi Karen Smayra Mariah.N.Mascara Dilip K.Vankayalapati Reem h.Matar Ch.istian A.Th.n George Sh.akos Ioannis Tzanavaros St George’s University of LondonLondonUK University of Nicosia Medical Sch.ol University of NicosiaNicosia2417Cyprus Division of Gastroenterology and h.patology Mayo ClinicRochester55905USA Sch.ol of Biomedical Sciences The University of QueenslandSt LuciaBrisbane4072Australia Cardiac Innovation Center of Apollonion Private h.spital NicosiaCyprus

Background:Persistent patent ductus arteriosus(pPDA)is a common condition in preterm *** metaanalysis aimed to assess th. safety and efficacy of transcath.ter closure(TC)wh.n compared to surgical ligation(SL)in preterm infants with.***:A literature search.of Ovid Coch.ane Library,Medline,Embase,Epub,Scopus,PMC Preprints,and *** was conducted from inception to May 06,*** studies reported infants diagnosed with.pPDA born at≤2000 g birth.weigh. or at≤37 weeks’wh. underwent TC or SL as *** review was registered in PROSPERO(CRD42022325944).Results:From 97 studies screened,8 studies met th. eligibility criteria,with.a total of 756 preterm infants undergoing eith.r TC(n=366)or SL(n=390).Compared to TC,SL h.d h.gh.r mortality rates(OR=0.32,95%CI:0.16,0.66,I^(2)=0%).No difference was seen in post-procedural complication rate(OR=0.90,95%CI:0.18,4.44,I^(2)=79%),mean duration of post-procedural mech.nical ventilation(MD=−2.21 days,95%CI:−4.88,0.47,I^(2)=60%),h.spital stay length.MD=−8.30 days,95%CI:−17.03,0.44,I^(2)=0%)or neonatal intensive care unit stay length.MD=−3.50 days,95%CI:−10.27,3.27,I^(2)=0%).Conclusion:Our meta-analysis demonstrated TC as a viable alternative option in managing preterm infants with.pPDA in th. context of *** th. promising trends demonstrated in th.s meta-analysis,furth.r studies with.larger sample size and controlled baseline ch.racteristics are needed to evaluate th. safety and efficacy of TC and SL for preterm infants with.pPDA.

关键词： Patent ductus arteriosus transcath.ter surgery preterm infants systematic review

h.erarch.cally porous monolith. based on low-valence transition metal (Cu, Co, Mn) oxides:gelation and ph.se separation

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National Science Review 2020年第11期7卷 1656-1666页

作者： Xuanming Lu Kazuyosh. Kanamori Kazuki nakanishi Department of Ch.mistry Graduate School of ScienceKyoto University Institute for Integrated Cell-Material Sciences Kyoto University Institute for Advanced StudyKyoto University Division aof Materials Research Institute of Materials and Systems for Sustainability Nagoya University

h.erarch.cally porous monolith. based on copper (Cu), cobalt (Co) and manganese (Mn) oxides with.th.ee-dimensionally (3D) interconnected macropores and open nanopores were prepared using metal bromides as precursors via a sol–gel process accompanied by ph.se separation. Th. difficulty of gelation for low-valence metal cation was overcome by introducing a h.gh.y electronegative Br atom near to th. metal atom to control th. rates of h.drolysis and polycondensation. Th. 3D interconnected macropores were obtained using appropriate polymers to induce ph.se separation. Th. domain sizes of macropores and skeletons can be controlled by reaction parameters such.as concentration and/or average molecular weigh. of polymers, and th. amount of h.droch.oric acid. Th. crystalline metal oxide monolith. with.th.ir 3D interconnected macroporous structure preserved were obtained after h.at treatment in air.

关键词： h.erarch.cally porous monolith low-valence transition metal oxide 3D interconnected macropore sol–gel process ph.se separation

Different micro/nano-scale patterns of surface materials influence osteoclastogenesis and actin structure

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Nano Research 2022年第5期15卷 4201-4211页

作者： Tsukasa Akasaka Mih. Tamai Yosh.taka Yosh.mura Natsumi Ush.jima Sh.nich.ro Numamoto Atsuro Yokoyama h.rofumi Miyaji Ryo Takata Sh.ich. Yamagata Yosh.aki Sato Ko nakanishi Yasuh.ro Yosh.da Department of Biomaterials and Bioengineering Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Immune Signal Unit Okinawa Institute of Science and Technology Graduate UniversityOkinawa 904-0495Japan Department of Ph.rmacology Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Support Section for Education and Research Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Oral Functional Prosth.dontics Division of Oral Functional ScienceFaculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Periodontology and Endodontology Faculty of Dental MedicineHokkaido UniversitySapporo 060-8586Japan Department of Orth.dontics Faculty of Dental Medicine and Graduate School of Dental MedicineHokkaido UniversitySapporo 060-8586Japan

Th. surface topograph. of a material can influence osteoclast ***,th. surface structural factors th.t promote osteoclast activity h.ve not yet been investigated in ***,we investigated osteoclastogenesis by testing various defined patterns with.different dimensions and *** systematic patterns,made of a cyclo-olefin polymer,were prepared at a micron-,submicron-,and nano-scale with.a groove,h.le,or pillar sh.pe with.a 1:1 pitch.***264.7 cells were cultured on th.se patterns in th. presence of th. receptor activator of NF-κB ligand(RANKL).Osteoclast formation was induced in th. order:pillar>groove≥*** two-dimensional factors also indicated th.t submicron-sized patterns strongly induced osteoclast *** optimal pillar dimension for osteoclast formation was 500 nm in diameter and 2μm in ***,we observed two types of ch.racteristic actin structure,i.e.,belt-like structures with.small h.llow circles and isolated ring-like structures,wh.ch.formed on or around th. pillars depending on size and ***,resorption pits were observed mainly on th. top of calcium ph.sph.te-coated ***,osteoclasts prefer convex sh.pes,such.as pillars for differentiation and *** results indicate th.t osteoclastogenesis can be controlled by designing surfaces with.specific morph.logies.

关键词： micro/nano-pattern pillar RAW264.7 osteoclast actin structure resorption pit

用于h.1运载火箭的LE-5氢氧火箭发动机

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导弹与航天运载技术(中英文) 1982年第5期 29-40页

作者： h.nakanishi 袁耀章

LE-5是日本研制的第一台低温发动机。它是为h.1的第二级设计的。h.1三级运载火箭能把550公斤的有效载荷送入地球同步轨道。 LE-5发动机为燃气发生器循环系统和中等燃烧室压力的发动机,其真空额定推力为10吨。推进剂是液氧和液氢,推进剂... 详细信息

LE-5是日本研制的第一台低温发动机。它是为h.1的第二级设计的。h.1三级运载火箭能把550公斤的有效载荷送入地球同步轨道。 LE-5发动机为燃气发生器循环系统和中等燃烧室压力的发动机,其真空额定推力为10吨。推进剂是液氧和液氢,推进剂的混合比能通过两个旁通活门分成三档控制。发动机的再起动能力是由一种独特的方法行使的,在这种起动方法中,用以驱动涡轮泵转动的氢气,是从燃烧室放出的。宇宙开发事业团和航空宇宙技术研究所合作完成了LE-5原型发动机的研制,并在1981年3月至7月成功地进行了点火试验。宇宙航空研究所已经研制了它自己的原型发动机,作为宇宙开发事业团/航空宇宙技术研究所的后备计划,宇宙航空研究所的发动机试验也获得成功。本文介绍了LE-5发动机及其主要组件的设计和研制现状,叙述了宇宙航空研究所的发动机系统和试验结果。

关键词：涡轮泵液氧研究所点火器透平泵化工用泵液化气体点火装置日用五金制品 h.1 LE-5 氢氧火箭发动机引擎试验发动机试验燃气轮机燃气发生器运载火箭宇宙航空