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International Journal of Mining Science and Technology 2024年第6期34卷 799-819页

作者： Wei Yao Shuai Wang Bangbiao Wu ying xu Kaiwen Xia State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation School of Civil EngineeringTianjin UniversityTianjin 300072China China Railway Design Corporation Tianjin 300308China Institute of Geosafety School of Engineering and TechnologyChina University of GeosciencesBeijing 100083China

Understanding the effects of microwave irradiation and thermal treatment on the dynamic compression and fragmentation properties of rocks is essential to quantify energy consumption in rock *** this study,Fangshan granite(FG)specimens were exposed to microwave irradiation and heat *** damage of FG specimens induced by these two methods was compared using X-ray CT scanning and ultrasonic wave *** temperatures of FG after microwave irradiation and thermal treatment were effectively evaluated using a newly proposed technique.A novelty method for precisely determining the geometric features of fragments is developed to estimate the fragmentation ***,the dynamic uniaxial compressive strength(UCS),the dynamic fragmentation characteristics,and the fragmentation energy of FG after these two pretreatment methods can be reasonably *** noticeable distinction of loading rate effect on the dynamic UCS of FG between these two pretreatment methods is first observed.A relationship is established between the dynamic UCS and the damage induced by microwave irradiation and heat ***,fragmentation energy fan analysis is introduced to accurately compare the fragmentation properties of FG after two pretreatment methods in dynamic compression tests.

关键词： Fangshan granite Dynamic experiments Microwave irradiation Thermal treatment Loading rate Fragmentation

Stability and transepithelial transport of oligopeptide(KRQKYD)with hepatocyte-protective activity from Jinhua ham in human intestinal Caco-2 monolayer cells

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Food Science and Human Wellness 2024年第3期13卷 1503-1512页

作者： Wen Nie Feiran xu Kai Zhou Jieying Deng ying Wang Baocai xu Engineering Research Center of Bio-process Ministry of EducationSchool of Food and Biological EngineeringHefei University of TechnologyHefei 230601China School of Biological and Food Engineering Chuzhou UniversityChuzhou 239001China

The study evaluated the stability of an oligopeptide(Lys-Arg-Gln-Lys-Tyr-Asp,KRQKYD)and its transport mechanism by simulating gastrointestinal digestion and a model of human intestinal Caco-2 monolayer cells in *** this study,the effects of environmental factors(temperature,pH and NaCl concentration)and simulated gastrointestinal digestion on the stability of KRQKYD were evaluated by indicators of the levels of alanine transaminase(ALT),aspartate transaminase(AST)and malondialdehyde(MDA)in an alcoholinduced hepatocyte injury *** results showed that KRQKYD still maintained satisfactory hepatocyteprotective activity after treatment with different temperatures(20-80℃),pH(3.0-9.0),NaCl concentration(1%-7%)and simulated gastrointestinal digestion,which indicated that KRQKYD showed good stability to environmental factors and simulated gastrointestinal ***,the intact KRQKYD could be absorbed in a model of Caco-2 monolayer cells with a P_(app)value of(9.70±0.53)×10^(-7)cm/*** with an energy inhibitor(sodium azide),a competitive peptide transporter inhibitor(Gly-Pro)and a transcytosis inhibitor wortmannin did not decrease the level of transepithelial KRQKYD transport,indicating that the transport mechanism of KRQKYD was not associated with energy dependent,vector mediated and *** tight junction disruptor cytochalasin D significantly increased the level of transepithelial KRQKYD transport(P<0.05),suggesting that intact KRQKYD was absorbed by paracellular transport.

关键词： Jinhua ham KRQKYD(Lys-Arg-Gln-Lys-Tyr-Asp) Environmental stability Gastrointestinal digestive Transport mechanism

N-doping offering higher photodegradation performance of dissolved black carbon for organic pollutants: experimental and theoretical studies

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第4期25卷 340-356页

作者： Yong GUO Mengxia CHEN Ting CHEN ying GUO Zixuan xu Guowei xu Soukthakhane SINSONESACK Keophoungeun KANMANY Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes Ministry of EducationCollege of EnvironmentHohai UniversityNanjing 210093China Key Laboratory of Environmental Engineering of Jiangsu Province Jiangsu Provincial Academy of Environmental ScienceNanjing 210036China State Key Laboratory of Pollution Control and Resource Reuse Nanjing UniversityNanjing 210023China Central Environmental Laboratory Natural Resources and Environment Research InstituteMinistry of Natural Resources and EnvironmentVientiane 999012Laos

We investigated the influence mechanism of N-doping for dissolved black carbon(DBC)photodegradation of organic *** degradation performance of N-doped dissolved black carbon(NDBC)for tetracycline(TC)(71%)is better than that for methylene blue(MB)(28%)under *** levels are both better than DBC degradation performances for TC(68%)and MB(18%)under *** species quenching experiments suggest that h and-O,are the main reactive species for NDBC photodegraded TC,while-OH and h*are the main reactive species for NDBC photodegraded MB.-OH is not observed during DBC photodegradation of *** is likely because N-doping increases valence-band(VB)energy from 1.55 eV in DBC to 2.04 eV in NDBC;the latter is strong enough to oxidize water to ***,N-doping increases the DBC band gap of 2.29 to 2.62 eV in NDBC,resulting in a higher separation efficiency of photo-generated electrons-holes in NDBC than in *** these factors give NDBC stronger photodegradation performance for TC and MB than ***-performance liquid chromatography-mass spectrometry(HPLC-MS)characterization and toxicity evaluation with the quantitative structure-activity relationship(QSAR)method suggest that TC photodegradation intermediates produced by NDBC have less aromatic structure and are less toxic than those produced by *** adopted a theoretical approach to clarify the relationship between the surface groups of NDBC and the photoactive species *** results add to the understanding of the photochemical behavior of NDBC.

关键词： Dissolved black carbon(DBC) N-doping Organic pollutants Band gap Photodegradation

Paroxysmal Kinesigenic Dyskinesia:Genetics and Pathophysiological Mechanisms

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Neuroscience Bulletin 2024年第7期40卷 952-962页

作者： Jiao-Jiao xu Hong-Fu Li Zhi-ying Wu Department of Medical Genetics and Center for Rare Diseases The Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009China Department of Neurology in the Second Affiliated Hospital Key Laboratory of Medical Neurobiology of Zhejiang ProvinceZhejiang University School of MedicineHangzhou 310009China

Paroxysmal kinesigenic dyskinesia(PKD),the most common type of paroxysmal movement disorder,is characterized by sudden and brief attacks of choreoathetosis or dystonia triggered by sudden voluntary *** is mainly caused by mutations in the PRRT2 or TMEM151A *** exact pathophysiological mechanisms of PKD remain unclear,although the function of PRRT2 protein has been well characterized in the last *** on abnormal ion channels and disturbed synaptic transmission in the absence of PRRT2,PKD may be channelopathy or synaptopathy,or *** addition,the cerebellum is regarded as the key pathogenic *** depolarization in the cerebellum is tightly associated with dyskinetic ***,in PKD,other than the cerebellum,the role of the cerebrum including the cortex and thalamus needs to be further investigated.

关键词： Paroxysmal kinesigenic dyskinesia PRRT2 TMEM151A Genetics Pathophysiological mechanisms

Collaborative positioning for swarms:A brief survey of vision,LiDAR and wireless sensors based methods

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Defence Technology（防务技术） 2024年第3期33卷 475-493页

作者： Zeyu Li Changhui Jiang Xiaobo Gu ying xu Feng zhou Jianhui Cui College of Geodesy and Geomatics Shandong University of Science and TechnologyQingdao266590China Geoloc Laboratory Universite Gustave EiffelParis77454France School of Automation Guangdong University of TechnologyGuangzhou510006China

As positioning sensors,edge computation power,and communication technologies continue to develop,a moving agent can now sense its surroundings and communicate with other *** receiving spatial information from both its environment and other agents,an agent can use various methods and sensor types to localize *** its high flexibility and robustness,collaborative positioning has become a widely used method in both military and civilian *** paper introduces the basic fundamental concepts and applications of collaborative positioning,and reviews recent progress in the field based on camera,LiDAR(Light Detection and Ranging),wireless sensor,and their *** paper compares the current methods with respect to their sensor type,summarizes their main paradigms,and analyzes their evaluation ***,the paper discusses the main challenges and open issues that require further research.

关键词： Collaborative positioning Vision LiDAR Wireless sensors Sensor fusion

METTL1 promotes colorectal cancer cell proliferation by attenuating CHEK2-induced G1/S phase arrest

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Genes & Diseases 2024年第2期11卷 579-581页

作者： Houxiang Jiang ying Liu Huibin Song Jinquan Xia ying Tian Luolin Wang Mingwei Li Zhenyu xu Zhenglei xu Chang Zou Department of Gastrointestinal Surgery The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)WuhuAnhui 241001China Anhui Province Clinical Research Center for Critical Respiratory Medicine WuhuAnhui 241001China Department of Clinical Medical Research Center The Second Clinical Medical College (Shenzhen People's Hospital) of Jinan UniversityThe First Affiliated Hospital of Southern University of Science and TechnologyShenzhenGuangdong 518020China Integrated Chinese and Western Medicine Postdoctoral Research Station Jinan UniversityGuangzhouGuangdong 510632China School of Pharmacy Southwest Medical UniversityLuzhouSichuan 646000China Department of Gastroenterology Shenzhen People's Hospital(The Second Clinical Medical CollegeJinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)ShenzhenGuangdong 518020China Precision Medicine Center The First Affiliated Hospital of Wannan Medical College(Yijishan Hospital of Wannan Medical College)WuhuAnhui 241001China School of Medicine Life and Health SciencesThe Chinese University of Hong KongShenzhenGuangdong 518172China

Colorectal carcinoma(CRC),the third most commonly diagnosed cancer,accounts for 9.7%of all newly diagnosed cancer cases and 9.4%of cancer-related deaths globally.1 Recent studies have demonstrated that post-transcriptional RNA modifications,such as N^(6)-methyladenosine,N^(5)-methylcytosine,and N^(7)-methylguanosine,play critical roles in the regulation of mRNA stability and translation,primary microRNA processing,and lncRNA-protein complex that contributes to the progression of human cancer.

关键词： cancer colorectal globally

Direct generation of Zn metal using laser-induced ZnS to eradicate carbon emissions from electrolysis Zn production

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Frontiers of Environmental Science & Engineering 2024年第1期18卷 83-95页

作者： ying Chen Ning Duan Linhua Jiang Fuyuan xu Guangbin Zhu Yao Wang Yong Liu Wen Cheng Yanli xu State Key Laboratory of Pollution Control and Resources Reuse College of Environmental Science and EngineeringTongji UniversityShanghai 200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China School of Environmental Science and Engineering Tianjin UniversityTianjin 300350China School of Materials Science and Engineering Anhui University of Science&TechnologyHuainan 232001China

In response to the goal of net-zero emissions proposed by Intergovernmental Panel on Climate Change, Chinese government has pledged that carbon emissions will peak by 2030, and achieve carbon neutrality by 2060. However, the high carbon energy structure of traditional industries has aggravated environmental problems, such as greenhouse effect and air pollution. The goal of carbon neutrality will be difficult to achieve without the development of disruptive theories and technologies. The electrolytic zinc industry requires high-temperature roasting at ~1000 ℃, generating large amounts of greenhouse gases and SO_(2). High concentrations of sulfuric acid (200 g/L) are subsequently used for electrolysis, and each ton of zinc produced generates 50 kg of anode slime with lead content of up to 16%, as well as 0.35 m3 of wastewater containing zinc and lead. To solve these problems, an optical metallurgy method is proposed in this study. The proposed method uses laser-induced photoreduction to decompose ZnS and reduce metal ions to metal. Results indicate that Zn0 and S8 can be detected on the surface of ZnS at a specific wavelength and laser fluence. The generation mechanism of Zn0 is such that laser induces an electronic transition that breaks ionic bond in ZnS, resulting in its decomposition and photoreduction to Zn0 under an inert argon gas atmosphere. This method does not reduce other metals in the mineral since it does not use high-temperature roasting, providing a new way of producing high-purity metal without greenhouse gas emissions and heavy metal pollution caused by traditional zinc electrolysis.

关键词： Laser metallurgy ZnS Photochemical reduction Zinc

Modeling method for SSC prediction in pomelo using Vis-NIRS with wavelength selection and latent variable updating

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International Journal of Agricultural and Biological Engineering 2024年第1期17卷 251-260页

作者： Hao Tian Shuai Wang Huirong xu Yibin ying College of Biosystems Engineering and Food Science Zhejiang UniversityHangzhou 310058China Key Laboratory of On-Site Processing Equipment for Agricultural Products Ministry of Agriculture and Rural AffairsHangzhou 310058China College of Food Science Shihezi UniversityShihezi 832003XinjiangChina

The aim of this study was in-line,rapid,and non-destructive detection for soluble solid content(SSC)in pomelos using visible and near-infrared spectroscopy(Vis-NIRS).However,the large size and thick rind of pomelo affect the stability of spectral acquisition and the biological variabilities affect the robustness of *** these issues,in this study,an efficient prototype in-line detection system in transmittance mode was designed and evaluated in comparison with an off-line detection *** from the years 2019 and 2020 were used for modeling and the external validation data were obtained by the inline detection system in *** wavelength selection methods of changeable size moving window(CSMW),random frog(RF),and competitive adaptive reweighted sampling(CARS)were used to improve the prediction accuracy of partial least squares regression(PLSR)*** best performance of internal prediction was obtained by CARS-PLSR and the determination coefficient of prediction(),root mean square error of prediction(RMSEP),and residual predictive deviation(RPD)were 0.958,0.204%,and 4.821,***,all models obtained large prediction biases in external *** latent variable updating(LVU)method was proposed to update models and improve the performance in external *** samples from the external validation set were randomly selected to update the *** with the recalibration method,LVU could effectively modify the original models which matched the SSC range of the external validation *** CSMW-PLSR models were more robust in external *** off-line model with LVU performed best with a root mean square error of validation(RMSEV)of 0.599%and the in-line model with recalibration obtained RMSEV of 0.864%.These results demonstrated the application potential of the transmittance Vis-NIRS for in-line rapid prediction of SSC in pomelos and the modeling and updating methods could be applied to samples with biological variabi

关键词： Vis-NIRS in-line detection external validation wavelength selection model updating pomelo SSC

A Unified Model Fusing Region of Interest Detection and Super Resolution for Video Compression

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Computers, Materials & Continua 2024年第6期79卷 3955-3975页

作者： Xinkun Tang Feng Ouyang ying xu Ligu Zhu Bo Peng School of Computer and Cyber Sciences Communication University of ChinaBeijing100024China Cable Television Technology Research Institute Academy of Broadcasting ScienceBeijing100866China

High-resolution video transmission requires a substantial amount of *** this paper,we present a novel video processing methodology that innovatively integrates region of interest(ROI)identification and super-resolution *** method commences with the accurate detection of ROIs within video sequences,followed by the application of advanced super-resolution techniques to these areas,thereby preserving visual quality while economizing on data *** validate and benchmark our approach,we have curated a new gaming dataset tailored to evaluate the effectiveness of ROI-based super-resolution in practical *** proposed model architecture leverages the transformer network framework,guided by a carefully designed multi-task loss function,which facilitates concurrent learning and execution of both ROI identification and resolution enhancement *** unified deep learning model exhibits remarkable performance in achieving super-resolution on our custom *** implications of this research extend to optimizing low-bitrate video streaming *** selectively enhancing the resolution of critical regions in videos,our solution enables high-quality video delivery under constrained bandwidth *** results demonstrate a 15%reduction in transmission bandwidth compared to traditional super-resolution based compression methods,without any perceivable decline in visual *** work thus contributes to the advancement of video compression and enhancement technologies,offering an effective strategy for improving digital media delivery efficiency and user experience,especially in bandwidth-limited *** innovative integration of ROI identification and super-resolution presents promising avenues for future research and development in adaptive and intelligent video communication systems.

关键词： Super resolution region of interest detection video compression

Single-structure 3-axis Lorentz force magnetometer based on an AlN-on-Si MEMS resonator

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Microsystems & Nanoengineering 2024年第3期10卷 75-86页

作者： Cheng Tu xu-heng Ou-Yang ying-jie Wu Xiao-sheng Zhang School of Integrated Circuit Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

This work presents a single-structure 3-axis Lorentz force magnetometer(LFM)based on an AlN-on-Si MEMS *** operation of the proposed LFM relies on the flexible manipulation of applied excitation currents in different directions and frequencies,enabling the effective actuation of two mechanical vibration modes in a single device for magnetic field measurements in three ***,the excited out-of-plane drum-like mode at 277 kHz is used for measuring the x-and y-axis magnetic fields,while the in-plane square-extensional mode at 5.4 MHz is used for measuring the z-axis magnetic *** different configurations of applied excitation currents ensure good crossinterference immunity among the three *** to conventional capacitive LFMs,the proposed piezoelectric LFM utilizes strong electromechanical coupling from the AlN layer,which allows it to operate at ambient pressure with a high *** understand and analyze the measured results,a novel equivalent circuit model for the proposed LFM is also reported in this work,which serves to separate the effect of Lorentz force from the unwanted capacitive *** demonstrated 3-axis LFM exhibits measured magnetic responsivities of 1.74 ppm/mT,1.83 ppm/mT and 6.75 ppm/mT in the x-,y-and z-axes,respectively,which are comparable to their capacitive counterparts.

关键词： resonator Lorentz structure