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Exosomal HOTAIR promotes proliferation, migration and invasion of lung cancer by sponging miR-203

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Science China(Life Sciences) 2020年第8期63卷 1265-1268页

作者： Chengcheng Zhang Lisha Xu guoying deng Yajie Ding Ke Bi Hansong Jin Jixin Shu Jia Yang Haibin deng Zhongqi Wang Yin Wang Department of Medical Oncology Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China Department of Ultrasound Shanghai Pulmonary HospitalTongji UniversityShanghai 200433China Shanghai General Hospital Shanghai Jiao Tong University School of MedicineShanghai 201620China Tongji Hospital Tongji University School of MedicineShanghai 200065China Gongli Hospital Pudong DistrictShanghai 200135China

Dear Editor,Lung cancer is one of the most common causes of cancerrelated deaths *** great progress in the development of lung cancer treatments,the prognoses of patients with advanced stage cancer remains poor(Torre ... 详细信息

关键词： invasion lung cancer

Degradable nanocatalyst enables antitumor/antibacterial therapy and promotion of wound healing for diabetes via self-enhanced cascading reaction

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Chinese Chemical Letters 2023年第7期34卷 155-161页

作者： Xiang Wang Cheng Ding Ziwen Zhang Chunlin Li Dongmiao Cao Linjing Zhao guoying deng Yu Luo Chunping Yuan Jie Lu Xijian Liu School of Chemistry and Chemical Engineering Shanghai Engineering Technology Research Center for Pharmaceutical Intelligent EquipmentShanghai Frontiers Science Research Center for Druggability of Cardiovascular Noncoding RNAInstitute for Frontier Medical TechnologyShanghai University of Engineering ScienceShanghai201620China Affiliated Sixth People's Hospital Shanghai JiaoTong UniversityShanghai 200233China Trauma Center Shanghai General HospitalShanghai Jiaotong University School of MedicineShanghai 201620China

Diabetic patients often have problems such as residual tumor and wound infection after tumor resection,causing severe clinical *** is urgent to develop effective therapies to reach oncotherapy/antiinfection/promotion of wound healing combined ***,we propose CS/MnO_(2)-GO_x (CMGO_x)nanocatalysts for the specific catalytic generation of ~·OH to inhibit tumors and bacteria in a hyperglycemic *** good biocompatible chitosan (CS),as a carrier for the catalyst,exhibits excellent antibacterial effect as well as promotes wound *** oxidase (GO_x) is loaded on the surface of CS nanoparticles to generate H_(2)O_(2) and gluconic acid by consuming glucose (starvation therapy,ST) and O_(2).The MnO_(2) depletes glutathione (GSH) to produce Mn^(2+),amplifying oxidative stress and further promoting the activity of Mn^(2+)-mediated Fenton-like reaction to produce~·OH (chemodynamic therapy,CDT)in weak acidic ***,the produced gluconic acid lowers the p H of the environment,enhancing chemodynamic therapy (ECDT).The tumor cells and bacteria are efficiently eliminated by the synergistic effect of ST and *** MnO_(2) nanoparticles at neutral environment decomposes H_(2)O_(2) into O_(2),which cooperate with CS to promote *** self-enhanced cascade reaction of CMGO_x in situ exhibits excellent effects of antitumor/antibacterial therapy and promotion of wound healing,offering a promising integrated treatment for diabetic patients after tumor surgical resection.

关键词： Self-cascade reaction Starvation therapy Chemodynamic therapy Antitumor Antibacterial Wound healing

Consideration for the Asia＇s Monetary Cooperation Based on the Theory of Optimum Currency Areas

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Chinese Business Review 2005年第9期4卷 10-14页

作者： Weidong Huo guoying deng Peng Wang Southwestern University of Finance and Economics

According to the theory and the standard of Optimum Currency Areas, this paper analyzes the possibility of the Asia＇s monetary cooperation. Based on the current study, this paper points out that East Asia does not have the condition for the monetary cooperation and the cooperation can only be conducted in a comparatively low level; furthermore, in order to achieve the monetary integration and to form the Optimum Currency Areas, it is still a long way to go for Asian countries. All the Asia countries should work hard in the political and economic area. However, the common interests will make the monetary cooperation an irreversible trend.

关键词： optimum currency areas monetary cooperation benchmark currency

Effects of Water Temperature on Male Fertility Alternation of the Sensitive TGMS Lines in Rice under the Simulated Low Air Temperature in High Summer

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Agricultural Science & Technology 2000年第3期1卷 7-12页

作者： Xiao guoying deng Xiaoxiang Yuan Longping (Hunan Hybrid Rice Research Center, Changsha, 410125) Hunan Hybrid Rice Research Center Changsha 410125

The effects of water temperature on male fertility alternation of TGMS lines in rice were studied under the simulated low air temperature conditions in summer. The results indicate that warm water with temperature higher than the critical temperature of TGMS lines is able to keep the lines’ male sterility stable under the air temperature below the critical temperature. These results provide theoretic basis for applying warm water as an effective measure to prevent the lines from the negative effects of the low air temperature occuring in summer in the course of seed production.

关键词： Low air temperature in summer Water temperature TGMS line Fertility.

基于机器学习的住院患者压力性损伤分析与预测

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同济大学学报（自然科学版） 2020年第10期48卷 1530-1536页

作者：李清苏强林英邓国英同济大学经济与管理学院上海200092 上海市第一人民医院护理部上海201620 上海市第一人民医院创伤中心上海201620

压力性损伤是护理工作的重点,也是评价护理质量的重要指标,设计合理的评估量表和科学预测是预防的关键措施。基于传统的12个指标,再新增3个风险指标,设计更全面的风险评估量表;据此收集一段时间内住院患者的信息,采用卡方检验分析对损... 详细信息

压力性损伤是护理工作的重点,也是评价护理质量的重要指标,设计合理的评估量表和科学预测是预防的关键措施。基于传统的12个指标,再新增3个风险指标,设计更全面的风险评估量表;据此收集一段时间内住院患者的信息,采用卡方检验分析对损伤有显著影响的指标,将患者分为入院时和院内获得性压力性损伤两类,分析其特征、产生部位和分布科室。基于支持向量机、概率神经网络和广义回归神经网络3种方法建立预测模型,在支持向量机中,采用高斯核函数构建模型,并使用遗传算法优化核函数参数。比较4种场景下3种方法的预测精度,支持向量机的预测准确率最高,达到84.68%,另外2种方法的准确率较低,均为82.78%。

关键词：压力性损伤支持向量机遗传算法概率神经网络广义回归神经网络

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住房价格对我国人口流动的影响

财经科学 2020年第2期 66-78页

作者：邓国营冯倩四川大学经济学院

本文旨在考察住房价格对人口流动的综合作用机制。在宏观层面,基于2005—2016年我国286个地级市的面板数据进行实证分析发现,不管是住房价格还是房价收入比的上升均显著地抑制了人口的净流入,其抑制作用表现为从东部到西部逐渐减弱;在... 详细信息

本文旨在考察住房价格对人口流动的综合作用机制。在宏观层面,基于2005—2016年我国286个地级市的面板数据进行实证分析发现,不管是住房价格还是房价收入比的上升均显著地抑制了人口的净流入,其抑制作用表现为从东部到西部逐渐减弱;在微观层面,房价上涨对不同收入水平的流动人口居留意愿的影响表现为"U"形,房价对收入较低群体和收入较高群体居留意愿的负向抑制作用更小。鉴于此,本文分区域为各地吸引人口流入、实现"人""居"均衡发展乃至最终实现经济可持续发展提出相应的政策建议。

关键词：住房价格人口流动均衡发展

行业选择与工资差异——来自大学毕业生劳动力市场的证据

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南开经济研究 2011年第1期 54-71页

作者：柴国俊邓国营西南财经大学经济与管理研究院四川大学经济学院

本文利用全国2008届大学毕业生求职与工作能力抽样调查数据,分析高、低收入行业的就业选择与工资收入的影响因素,并测算行业工资差异的大小及构成。结果发现,男性、211院校毕业或有良好家庭背景的大学毕业生更容易进入高收入行业工作,... 详细信息

本文利用全国2008届大学毕业生求职与工作能力抽样调查数据,分析高、低收入行业的就业选择与工资收入的影响因素,并测算行业工资差异的大小及构成。结果发现,男性、211院校毕业或有良好家庭背景的大学毕业生更容易进入高收入行业工作,能力对行业选择与工资收入影响显著;行业工资差异高达41%,其中超过80%的差异归因于行业分割,余下差异中地区因素占主导地位;去除垄断性行业能够降低高、低收入行业工资差异与分割比重,并提升能力解释力。

关键词：大学毕业生行业选择工资差异能力 Neumark分解

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住房价格区域分化:基于市场化进程的视角

财经科学 2023年第3期 140-148页

作者：邓国营田袁果四川大学经济学院

我国房价的区域分化已经成为一个不争的事实,诸多因素在推动这一现象的不断加剧。本文以我国除香港地区、澳门地区、台湾地区外的31个省级行政区为样本,识别了区域市场化程度与房价的因果关系,检验市场化程度在房价区域分化中所产生的... 详细信息

我国房价的区域分化已经成为一个不争的事实,诸多因素在推动这一现象的不断加剧。本文以我国除香港地区、澳门地区、台湾地区外的31个省级行政区为样本,识别了区域市场化程度与房价的因果关系,检验市场化程度在房价区域分化中所产生的实际影响,以及内在的逻辑机制。研究表明,市场化程度的提升对房价有显著的推动作用,这一推动作用在房价较高的地区更强,一定程度上解释了我国房价的区域分化现象的内在原因。其主要影响机制是,人口会因市场化程度高的地区拥有更好的制度环境而选择流入,进而增加这些地区的住房需求。进一步,本文还实证分析了市场化指数构成中各子维度对房价的影响效应,体现在要素市场的发育程度以及市场中介组织发育和法治环境的影响上。

关键词：住房价格市场化程度区域分化

Studies on Heteroses of Pei'ai 64S/Javanica Rice

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Hunan Agricultural Science ＆ Technology Newsletter 2002年第3期3卷 4-10页

作者： Tang Li, Xiao guoying, Yuan Longping, and deng XiaoxiangChina National Hybrid Rice Research and Development Center, Changsha 410125, China China National Hybrid Rice Research and Development Center Changsha 410125 China

Agronomic traits and heteroses of javanica varieties and the indica/javanica hybrids in Changsha are reported. Javanica rice exhibits long panicles, big grains, less panicles per plant, a long growth duration and high plant height in Changsha. The hybrid of Pei'ai 64S/javanica possesses positive heterobeltiosis in culm height, panicle length, panicles per plant, spikelets per panicle, grains per panicle, yield per plant, theoretic yield per hectare and actual yield per hectare; performs negative heterobeltiosis in days to flower, seed setting rate and 1000-grain weight. There are significant linear regression relations between culm height of the hybrid and panicle length of its male parent, panicle length of the hybrid and that of its male parent, spikelets per panicle of the hybrid and spikelets per panicle and panicle length of its male parent, grains per panicle of the hybrid and spikelets per panicle of its male parent, 1000-grain weight of the hybrid and spikelets per panicle of its male parent, respectively. In general, significant differences at 1% level are seen in most traits except grains per panicle and theoretic yield per hectare between the indica/javanica hybrid and Pei'ai 64S/Teqin (CK). Compared with the check, the indica/javanica hybrids have positive Standard heterosis in culm height, panicle length, spikelets per panicle, grains per panicle and 1000-grain weight but negative standard heterosis in days to flower, panicles per plant, seed setting rate, theoretic yield per hectare and actual yield per hectare. For the individuals, 11.1% hybrids possess > 40% standard heterosis in theoretic yield per hectare, 3.7% possess >40% standard heterosis in actual yield per hectare. The javanica restorer line 770 derives from a single cross of Pei'ai 64S/Moroberekan B-51-4-9-2. The hybrid 43S/770 possesses an elite plant type and strong heterosis.

关键词： javanica rice Pei'ai 64S heterosis hybrid rice