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A Waveguide Gate-Type Complex Detecting Mechanism on Micro-Channel Plate Substrate

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Chinese Journal of Electronics 2019年第3期28卷 625-629页

作者： MU Yining FAN Haibo liu Chunyang liu guozhen School of Science Changchun University of Science and Technology

The waveguide gate-type mechanism on micro-channel plate substrate was firstly put forward for the complex photo detection in Free space optical communication(FSO). Based on the losses of energy coupling between both Micro-channel plates(MCP), we further proposed waveguide gate-type complex detecting mechanism, which was verified in electron optic system by vacuum testing. With the application of the complex detecting mechanism, the device performance has greatly improved, including higher space optical transfer and wider dynamic detecting range.

关键词： Detectors Guided waves Free-space optical communication

Two-dimensional MXene hollow fiber membrane for divalent ions exclusion from water

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Chinese Journal of Chemical Engineering 2022年第1期35卷 260-266页

作者： guozhen liu Yanan Guo Baochun Meng Zhenggang Wang Gongping liu Wanqin Jin State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China

Two-dimensional material membranes with fast transport channels and versatile chemical functionality are promising for molecular ***,for the first time,we reported design and engineering of two-dimensional Ti_(3)C_(2)Tx MXene(called transition metal carbides and nitrides)membranes supported on asymmetric polymeric hollow fiber substrate for water *** membrane morphology,physicochemical properties and ions exclusion performance were systematically *** results demonstrated that surface hydrophilicity and electrostatic repulsion and size sieving effect of interlayer channels synergistically endowed the MXene hollow fiber membrane with fast water permeation and efficient rejection of divalent ions during nanofiltration process.

关键词： Two-dimensional material MXene membranes Hollow fiber Desalination Nanofiltration

Highly efficient and stable perovskite solar cells with strong hydrophobic barrier via introducing poly(vinylidene fluoride)additive

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Journal of Energy Chemistry 2021年第6期30卷 593-600,I0014页

作者： Haiying Zheng guozhen liu Weiwei Wu Huifen Xu Xu Pan Institutes of Physical Science and Information Technology Anhui UniversityHefei 230601AnhuiChina Key Laboratory of Photovoltaic and Energy Conservation Materials Institute of Solid State PhysicsHefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031AnhuiChina

Perovskite solar cells(PSCs)have become the promising next-generation photovoltaic devices due to their excellent photoelectric performances,and the power conversion efficiencies(PCEs)have experienced unprecedented rapid increase in recent ***,to realize the practical application of PSCs,high performance and long-term stability are required and the preparation of high-quality perovskite film is the ***,we adopt a simple and effective method to prepare high-quality perovskite films by introducing the poly(vinylidene fluoride)(PVDF)polymer additive with abundant hydrophobic *** the growth template,the PVDF promotes the growth of perovskite crystal,improves the crystallinity and film morphology,thus reducing defect density and inhibiting carrier *** results show that the photovoltaic performances of the perovskite device with PVDF are meaningfully improved,and a high PCE of 21.42%is achieved with an improvement of 10.87%,More importantly,the PVDF-based perovskites display greatly enhanced humidity and heat stability due to the protection of strong hydrophobic barrier from F and PVDF long *** at 45%±5%relative humidity(RH)for 2400 h and 850 C for300 h,respectively,the unsealed PVDF devices can maintain over 90%of the initial *** indicates that suitable polymer additives can improve the film quality to acquire high-performance and stable PSCs and lay a foundation to design new perovskite light absorption layer with different polymers for the further development of PSCs.

关键词： Perovskite solar cells Poly(vinylidene fluoride) Polymer additive Hydrophobic barrier Long-term stability

On-chip structure-switching aptamer-modified magnetic nanobeads for the continuous monitoring of interferon-gamma ex vivo

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Microsystems & Nanoengineering 2019年第1期5卷 281-291页

作者： guozhen liu Chaomin Cao Shengnan Ni Shilun Feng Hui Wei Graduate School of Biomedical Engineering ARC Centre of Excellence in Nanoscale Biophotonics(CNBP)Faculty of EngineeringThe University of New South WalesSydneyNSW 2052Australia Australian Centre for NanoMedicine UNSW SydneySydneyNSW 2052Australia International Joint Research Center for Intelligent Biosensor Technology and Health College of ChemistryCentral China Normal University430079 WuhanPR China School of Engineering Faculty of Science and EngineeringMacquarie UniversitySydneyNSW 2109Australia

Cytokines are cell signaling molecules that indicate the health status of the *** this study,we developed a microfluidic device integrated with structure-switching aptamers capable of continuously tracking the concentration of the cytokine interferon gamma(IFN-γ)in cell culture medium and blood ***,a ferrocene(Fc)-labeled structure-switching signaling aptamer with a hairpin structure targeting IFN-γwas immobilized on magnetic nanobeads by the strongest noncovalent interactions between streptavidin and *** aptamer-modified magnetic nanobeads were trapped on a customized microfluidic chip by a magnetic field to form the sensing *** binding of IFN-γcould trigger the hairpin structure of the aptamer to unfold,pushing Fc redox molecules away from the sensing interface and consequently switching off the electrochemical *** change in the redox current of Fc was quantitatively related to the concentration of IFN-γin a linear range of 10–500 pg mL^(−1)and with the lowest detection limit of 6 pgmL^(−1).This microfluidic device was specific to IFN-γin the presence of overabundant serum proteins and allowed the continuous monitoring of IFN-γwithout adding exogenous *** provided a universal point-of-care biosensing platform for the real-time detection of a spectrum of analytes.

关键词： beads structure magnetic

Protein microarray:A key approach of proteomics

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Frontiers in Biology 2010年第4期5卷 331-338页

作者： Wei HUANG Lin WU guozhen liu Siqi liu Beijing Institute of Genomics Chinese Academy of SciencesBeijing 100029China

Proteins are vital parts of living organisms,for they consist of the main components of physiological metabolic *** expression and modification status of proteins in cells are time-and space-dependent based upon functions as well as responses to stress.A subject aiming at understanding of protein status under certain physiological condition in a large scale,termed proteomics,is fundamentally important in life *** the proteomic investigation mainly relies on electrophoresis,liquid chromatography,and mass spectrometry,protein microarray is emerging as one of new techniques,and its power is being recognized in the field ***,we highlight progress in protein microarray,both its generation and application.

关键词： proteomics protein chip autoantibody protein interactions microarray preparation

Multiplexed Profiling of Extracellular Vesicles for Biomarker Development

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Nano-Micro Letters 2022年第1期14卷 59-94页

作者： Cheng Jiang Ying Fu guozhen liu Bowen Shu Jason Davis George K.Tofaris Nuffield Department of Clinical Neurosciences New Biochemistry BuildingUniversity of OxfordOxford OX13QUUK Department of Chemistry University of OxfordOxford OX13QZUK School of Life and Health Sciences The Chinese University of Hong KongShenzhen 518172People’s Republic of China Dermatology Hospital Southern Medical UniversityGuangzhou 510091People’s Republic of China Kavli Institute for Nanoscience Discovery New Biochemistry BuildingUniversity of OxfordOxfordUK

Extracellular vesicles(EVs)are cell-derived membranous particles that play a crucial role in molecular trafficking,intercellular transport and the egress of unwanted *** have been implicated in many diseases including cancer and *** are detected in all bodily fluids,and their protein and nucleic acid content offers a means of assessing the status of the cells from which they *** such,they provide opportunities in biomarker discovery for diagnosis,prognosis or the stratification of diseases as well as an objective monitoring of *** simultaneous assaying of multiple EV-derived markers will be required for an impactful practical application,and multiplexing platforms have evolved with the potential to achieve ***,we provide a comprehensive overview of the currently available multiplexing platforms for EV analysis,with a primary focus on miniaturized and integrated devices that offer potential step changes in analytical power,throughput and consistency.

关键词： Multiplexed profiling Extracellular vesicles Exosomes Liquid biopsy Point-of-care Biomarker

Transcriptional Characteristics of Xa21-mediated Defense Responses in Rice

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Journal of Integrative Plant Biology 2011年第4期53卷 300-311页

作者： Qiang Gan Hui Bai Xianfeng Zhao Yong Tao Haipan Zeng Yuning Han Wenyuan Song Lihuang Zhu guozhen liu Institute of Genetics and Developmental Biology the Chinese Academy of Sciences Beijing 100101 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China Beijing Institute of Genomics the Chinese Academy of Sciences Beijing 101300 China Department of Plant Pathology University of Florida Gainesville FL 32611 USA College of Life Sciences Agricultural University of Hebei Baoding 071001 China

Bacterial blight,caused by Xanthomonas oryzae ***（Xoo）,is the most destructive bacterial disease of *** cloned rice gene Xa21 confers resistance to a broad spectrum of Xoo *** identify genes involved in Xa21-mediated immunity,a whole-genome oligonucleotide microarray of rice was used to profile the expression of rice genes between incompatible interactions and mock treatments at 0,4,8,24,72 and 120 h post inoculation（hpi） or between incompatible and compatible interactions at 4 hpi,respectively.A total of 441 differentially expressed genes,designated as XDGs（Xa21 mediated differentially expressed genes）,were *** on their functional annotations,the XDGs were assigned to 14 categories,including defense-related,signaling,transcriptional *** of the defense-related genes belonged to the pathogenesis-related gene family,which was induced dramatically at 72 and 120 ***,most signaling and transcriptional regulator genes were downregulated at 4 and 8 hpi,suggesting that negative regulation of cellular signaling may play a role in the Xa21-mediated defense *** of expression profiles between Xa21- and other R gene-mediated defense systems revealed interesting common *** XDGs with supporting evidences were also discussed.

关键词： XANTHOMONAS diseases BACTERIAL diseases of plants RICE -- Diseases & pests PLANT clones CELLULAR signal transduction MOLECULAR genetics TRANSCRIPTION factors GENETIC transcription PLANT defenses RICE GENETICS

Beijing Philatelic Items with Strong National Characteristic

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中国邮政 1985年第1期 44-45页

作者： liu guozhen

To meet the wishes of stamp col-lectors at home and abroad, bringunique national characteristic intofull play. enrich people’s cultural lifeand build up the socialist spiritualcivilization, the Beijing StampCompany (BSC) issues specially-designed FDCs, folders, limited post-cards and past-marked envelopes ofdifferent styles to suit the occasionswhen new sets of stamps are issued bythe Ministry of Post andTelecommunications.

关键词： PRC Beijing Philatelic Items with Strong National Characteristic over BSC

Improved electrical and magnetic transport properties of La(0.8)Ba(0.2)MnO3 thin films by oxygen annealing

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Science China(Physics,Mechanics & Astronomy) 2016年第7期59卷 88-89页

作者： XiaoXia Chen guozhen liu Xia Zhu Jie Qiu JinLei Yao Meng Zhao YuCheng Jiang Run Zhao Ju Gao Research Center for Solid State Physics and Materials School of Mathematics and Physics Suzhou University of Science and Technology Suzhou 215009 China

Dear Editors, The properties of mixed-valence manganites are sensmve to the synthesis conditions [ 1 ]. For oxide films grown by pulsed laser deposition （PLD）, the physical properties are affected obviously by the growth oxygen pressure and annealing treat- ment [2-5]. Using the PLD method, manganite oxides are usually grown at different oxygen pressures to investigate the effects of oxygen content on their properties. However,

关键词：氧化物薄膜锰氧化物输运性质退火处理 PLD方法脉冲激光沉积合成条件混合价态