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Food Science and Human Wellness 2024年第1期13卷 191-197页

作者： Xueqi li Wenjun Ma Ting Yang Chong Wang Wei Zhang hui li Ting Zhao Xiaofei guo Institute of Nutrition&Health School of Public HealthQingdao UniversityQingdao 260071China Affiliated Hospital of Qingdao University Qingdao 260071China

The associations of individual amino acid with non-alcoholic fatty liver disease(NAFLD)risk remained *** present study aimed to investigate the associations between the two in the Chinese ***:A community-based health check-up program was conducted in Qingdao,*** was diagnosed by ultrasonography accompanied by epidemiological *** dietary intakes of amino acids were investigated with 3-day,24-h dietary records and calculated by Nutrition Calculator *** cubic spline model was used to evaluate a nonlinear relationship between amino acid intake and NAFLD ***:400 NAFLD subjects were identified,and 400 participants were randomly selected as controls and matched by gender and age(±3 years)Dose-response analysis showed that 1000 mg increment of aromatic amino acids(AAAs)was associated with reduced 16%risk of *** increments of 750 mg/d threonine,950 mg/d valine,or 1700 mg/d lysine were associated with a 20%reduction in the NAFLD risk(all P for linearity<0.05).Conclusion:The present study demonstrated that the dietary increases in milk,eggs and deep-sea fish,which are rich in the amino acids,might contribute to protecting against NAFLD in the elderly.

关键词： Amino acid Non-alcoholic fatty liver disease Senior citizen Dose-response analysis

小型猪实验验证内镜逆行新视野的临床安全性及有效性

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中国现代普通外科进展 2024年第1期27卷 14-18页

作者：匡哲李鹏金大庆张永潮郭慧丽张宇飞贺光琳孙国锋贺渊首都医科大学附属北京友谊医院消化内科北京100050 北京市平谷区卫生健康委员会北京101200 首都医科大学附属北京友谊医院平谷医院消化内科北京101200 首都医科大学附属北京友谊医院平谷医院普外科北京101200 杭州海康慧影科技有限公司浙江杭州310051

目的:应用小型猪验证内镜逆行新视野的临床安全性及有效性。方法:选取6只活体小型猪作为研究对象,选用内镜逆行新视野(ERNV)。评价其操作性能、图像质量并记录术中和术后并发症。评估实验动物能否全部完成相关内镜检查。验证ERNV的操作... 详细信息

目的:应用小型猪验证内镜逆行新视野的临床安全性及有效性。方法:选取6只活体小型猪作为研究对象,选用内镜逆行新视野(ERNV)。评价其操作性能、图像质量并记录术中和术后并发症。评估实验动物能否全部完成相关内镜检查。验证ERNV的操作性能及能否顺利通过十二指肠镜进入胆管,明确注水、吸引及器械通道是否通畅。分析胆道镜图像清晰度、颜色分辨率,有无图像变形及失真,能否准确评估管腔内情况及清晰观察黏膜表面情况。观察检查过程中无出血、穿孔等操作性损伤,以及呼吸抑制、心脏骤停等不良事件。观察术后所有猪存活状态及有无不良反应。结果:6只小型猪胆道镜均成功置入胆管内,该产品操作性能较佳,可顺利通过十二指肠镜进入胆管,其注水、吸引及器械通道相对通畅。此外,内镜图像较为清晰、颜色分辨率较佳,且无变形和失真,可实现对管腔内情况的准确评估,较为清晰地观察黏膜表面情况。所有小型猪均未发生胆管狭窄或扩张,胆管黏膜较为光滑,无充血水肿,无黏膜血管的异常增粗或弯曲。检查过程中无出血、穿孔等操作性损伤,未发生呼吸抑制、心脏骤停等不良事件。术后所有小型猪各项生命体征均趋于稳定,存活状态良好,且无胆管炎、出血及穿孔等并发症。结论:ERNV临床安全性及有效性均较佳,具有操作性能佳、图像质量优等特点,值得临床推广应用。

关键词：动物实验内镜安全性有效性猪

A widely used nonionic surfactant with desired functional groups as aqueous electrolyte additives for stabilizing Zn anode

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Rare Metals 2024年第8期43卷 3692-3701页

作者： Yue-Xian Song Xiao-Feng Wang Cai-Bin liu Kai-Xuan guo Xu-Huan guo Xiao-Bin Zhong Yao-hui Zhang Kai Wang hui-Juan guo li-Xin Zhang Jun-Fei liang School of Energy and Power Engineering North University of ChinaTaiyuan 030051China Key Laboratory of Green Chemical Process of Ministry of Education Hubei Key Laboratory of Novel Chemical Reactor and Green Chemical TechnologySchool of Chemical Engineering and PharmacyWuhan Institute of TechnologyWuhan 430073China Shanxi Provincial Key Laboratory for High Performance Battery Materials and Devices Taiyuan 030051China

Aqueous Zn-ion batteries(AZIBs) have emerged as potential candidates for li-ion batteries due to their intrinsic safety and high ***,metallic Zn anodes encounter dendrite growth and water-induced corrosion,rendering poor stability and severe irreversibility at the electrode/electrolyte interface during *** stabilize the Zn anode,we report a low-cost and effective nonionic surfactant,Tween-20 polymer,as an electrolyte additive for *** Tween-20,sequential oxyethylene groups tended to be preferentially adsorbed on the Zn electrode to form a shielding layer for regulating uniform Zn ***,the hydrophobic hendecyl chains prevented H_(2)O-induced corrosion on the Zn anode *** from the desired functional groups,when only trace amounts of Tween-20(0.050 g·L^(-1)) were used,the Zn anode displayed good cycling stability over 2170 h at10 mA·cm^(-2) and a high average Coulombic efficiency of98.94% over 1000 *** Tween-20 polymer can also be effectively employed in MnO_(2)/Zn full *** their toxicity,price and amount of usage,these surfactant additives provide a promising strategy for realizing the stability and reversibility of high-performance Zn anodes.

关键词： Zn anode Dendrite growth Tween-20 polymer Surfactant additive Aqueous electrolyte

Primary anaplastic lymphoma kinase-positive large B-cell lymphoma of the left bulbar conjunctiva: A case report

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World Journal of Clinical Cases 2024年第3期12卷 657-664页

作者： Xiao-Hong guo Chu-Bin li hui-hui Cao Gen-Yuan Yang Department of Pathology Zhuhai People's Hospital(Zhuhai Hospital Affiliated with Jinan University)Zhuhai 519000Guangdong ProvinceChina Endoscopy Center Zhuhai People's Hospital(Zhuhai Hospital Affiliated with Jinan University)Zhuhai 519000Guangdong ProvinceChina

BACKGROUND Anaplastic lymphoma kinase(ALK)-positive large B-cell lymphoma(LBCL)is an aggressive and rare variant of diffuse ***,we report an uncommon case of stage IE extranodal ALK-positive LBCL initially originating in the bulbar *** SUMMARY A 63-year-old woman presented with a mass in the left bulbar conjunctiva that had persisted for six months,accompanied by swelling and pain that had per-sisted for 3 *** examination revealed an 8 mm slightly elevated pink mass in the lower conjunctival sac of the left ***,the tumor was com-posed of large immunoblastic and plasmablastic large lymphoid cells with scattered anaplastic or multinucleated large ***,the neoplastic cells were positive for ALK,CD10,CD138,Kappa,MUM1,BOB.1,OCT-2,CD4,CD45,EMA,CD79a,CD38,and AE1/AE3,and negative for CD20,PAX5,Lambda,BCL6,CD30 and all other T-cell *** results of gene rearrangement tests showed monoclonal IGH/IGK/IGL and TCRD *** in situ hybridization studies did not reveal any BCL2,BCL6 or MYC ***,Epstein-Barr virus was not detected by in situ hybridization in the *** on the histopathological and imaging examinations,the neoplasm was classified as stage IE ALK-positive *** further treatments were *** the 6,15,and 21 mo postoperative follow-up visits,the patient was in good condition,without obvious *** case represents the first example of primary extranodal ALK-positive LBCL presenting as a bulbar conjunctival mass,which is extremely rare and shares morphological and immunohistochemical features with a variety of other neo-plasms that can result in *** Awareness of the condition presented in this case report is necessary for early and accurate diagnosis and appropriate treatment.

关键词： Anaplastic lymphoma kinase Large B-cell lymphoma Conjunctiva Immunoglobulin/T-cell receptor gene Immunohistochemistry Case report

Enhanced electrochemical performance of li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3) solid electrolyte by anion doping

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Nano Research 2024年第3期17卷 1465-1472页

作者： Jingrui Kang Xu guo Rui Gu Honglei Hao Yi Tang Jiahui Wang li Jin Hongfei li Xiaoyong Wei Electronic Materials Research Laboratory Key Laboratory of the Ministry of Education&International Center for Dielectric ResearchSchool of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an 710049China School of Energy and Materials Shanghai Key Laboratory of Engineering Materials Application and EvaluationShanghai Polytechnic UniversityShanghai 201209China

Nowadays,the majority of the studies on the substitution are focused on cations(such as Y^(3+),Ti^(4+),P^(5+),etc.)in li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3)(LATP),while there are few studies on the substitution of anion O^(2-).In this work,the modified LATP with a series of liCl(LATPClx,x=0.1,0.2,0.3,0.4)additives is prepared to enhance ionic *** successful introduction of Cl-makes the length of the c axis decrease from 20.822(2)to 20.792(1)Å,and the bulk conductivity of 2.13×10^(-3) S·cm^(-1) is achieved in LATPCl_(0.3).Moreover,the Al/Ti-O1/Cl1 and Al/Ti-O_(2)/Cl_(2) distance decrease,while the li1-O_(2)/Cl_(2) distance *** ions migrate more easily in the nanochannel of *** addition,the liCl additive increases the relative density and the grain boundary conductivity of LATPClx ***,a higher ionic conductivity of 2.12×10^(–4) S·cm^(-1) and a low activation energy of 0.30 eV are obtained in LATPCl_(0.3).Correspondingly,the symmetric cell exhibits a low overpotential of±50 mV for over 200 h in LATPCl_(0.3).The solid-state li|LATPCl_(0.3)|NCM811(NCM811=liNi0.8Co0.1Mn0.1O_(2))battery exhibits high initial capacity 185.1 mAh·g^(-1) with a capacity retention rate of 95.4%after 100 cycles at 0.5 *** result suggests that liCl additive is an effective strategy to promote electrochemical properties of LATP solid electrolyte and can be considered for reference to other inorganic solid electrolytes systems.

关键词： li_(1.3)Al_(0.3)Ti_(1.7)(PO_(4))_(3)(LATP)solid electrolyte anion doping ionic conductivity cyclic performance

Systemic immune-inflammation index combined with pediatric appendicitis score in assessing the severity and prognosis for paediatric appendicitis

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2565-2573页

作者： li-Ming guo Zhi-hui Jiang Hong-Zhen liu Department of General Surgery Qingdao Women and Children’s HospitalQingdao 266000Shandong ProvinceChina Department of Pediatric Surgery Children's Hospital Affiliated to Shandong UniversityJinan 250022Shandong ProvinceChina Department of Pediatric Surgery Jinan Children's HospitalJinan 250022Shandong ProvinceChina

BACKGROUND Pediatric appendicitis is a common cause of abdominal pain in children and is recognized as a significant surgical emergency.A prompt and accurate diagnosis is essential to prevent complications such as perforation and *** To investigate the predictive value of the systemic immune-inflammation index(SII)combined with the pediatric appendicitis score(PAS)for the assessment of disease severity and surgical outcomes in children aged 5 years and older with *** Clinical data of 104 children diagnosed with acute appendicitis were *** participants were categorized into the acute appendicitis group and chronic appendicitis group based on disease presentation and further stratified into the good prognosis group and poor prognosis group based on *** SII and PAS were measured,and a joint model using the combined SII and PAS was constructed to predict disease severity and surgical *** Significant differences were observed in the SII and PAS parameters between the acute appendicitis group and chronic appendicitis *** analysis showed associations among the SII,PAS,and disease severity,with the combined SII and PAS model demonstrating significant predictive value for assessing disease severity[aera under the curve(AUC)=0.914]and predicting surgical outcomes(AUC=0.857)in children aged 5 years and older with *** The study findings support the potential of integrating the SII with the PAS for assessing disease severity and predicting surgical outcomes in pediatric appendicitis,indicating the clinical utility of the combined SII and PAS model in guiding clinical decision-making and optimizing surgical management strategies for pediatric patients with appendicitis.

关键词： Systemic immune-inflammation index Pediatric appendicitis score Disease severity Surgical outcomes Risk factor Logistic regression Receiver operating characteristic analysis

EFFECT OF Zr,Cr AND B ADDITIVES ON MICROSTRUCTURE AND MECHANICAL PROPERTIES OF Ni_3Al ALLOYS

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Acta Metallurgica Sinica(English Letters) 1990年第3期3卷 170-176页

作者： guo Jianting li hui SUN Chao ZHU Yaoxiao Institute of Metal Research,Academia Sinica,Shenyang,China guo Jianting,Professor,Institute of Metal Research,Academia Sinica,Shenyang 110015,China

The microstructure and the mechanical properties from room temperature up to 1050℃ of Ni_3Al alloys containing 0—0.6 at.-%Zr,0—7.7 at.-%Cr and 0—2.22 at.-%B have been *** was found that the temperature dependence of their yield strength variation reveals to be anomalous,*** strength increases with the temperature raising,and then decreases till it surpassed the peak *** Zr and Zr+Cr may improve the yield strength of the al- loys in the entire range of testing temperatures,as well as the tensile strength and elongation under high temperatures.B is favourable to raise the tensile and yield strengths of the alloys, and also *** the strength will reduce as B added is over 2.22 at.-%.The Ni_(20)Al_3B_6 and Ni_3Al eutectic mixture like islands and globes precipitated inside the grains and along the grain bounderies,which are harmful to the strength and ductility,may be formed when the B content exceeds the limit of solubility.

关键词： Ni_3Al microstructure mechanical property yield strength

Inversion method of deflection of the vertical based on SWOT wide-swath altimeter data

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Geodesy and Geodynamics 2024年第4期15卷 419-428页

作者： Xin liu Menghao Song Chao li Guihua hui Jinyun guo Yongjun Jia Heping Sun College of Geodesy and Geomatics Shandong University of Science and TechnologyQingdao 266590China Weicheng Branch of Natural Resources and Planning Bureau of Weifang City Weifang 261021China National Satellite Ocean Application Service Beijing 100081China State Key Laboratoryof Geodesy and Earth's Dynamics Innovation AcademyforPrecision Measurement Science and TechnologyChinese Academy of ScienceWuhan 420071China

The deflection of the vertical(DOV)is the key information in the study of ocean gravity ***,in most areas,the precision of the prime component of DoV is significantly lower than that of the meridian *** obtain higher accuracy and resolution of ocean gravity information,researchers have proposed a novel altimeter called the wide-swath *** altimeter allows for the simultaneous acquisition of high-precision and high-resolution two-dimensional measurements of sea surface height(SSH).In this paper,the Surface Water and Ocean Topography(SWOT)mission with a wide-swath altimeter on board is selected for *** cycle of swoT sea surface height data is simulated to inverse the DOV in the Arabian Sea(45°E—80°E,0°-30°N),and the inversion results are compared with those of conventional altimeter *** results demonstrate that the difference between the meridian and prime components derived from the inversion of swoT wide-swath data is minimal,significantly outperforming the inversion results of conventional nadir altimeter *** advantage of swoT wide-swath altimeter lies in its ability to use the multi-directional geoid slope at any sea surface measurement point to invert the components in the meridian and prime *** investigate the impact of this advantage on inversion precision,this paper employs a method to calculate the gradient of the geoid in multiple directions to invert DoV *** improvement effect of calculating the gradient of the geoid in multiple directions on the precision of DoV component is *** is found that the accuracy of DoV inversion has significantly improved with the increase of geodetic gradient calculation *** addition,the effects of various errors and grid spacing in SwoT wide sea surface height data on the precision of Dov inversion are also analyzed.

关键词： SWOT Wide-swath altimeter Inversion method of Dov Multi-directional Arabian sea

Biomarkers and potential pathogenesis of colorectal cancer-related ischemic stroke

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World Journal of Gastroenterology 2018年第43期24卷 4950-4958页

作者： Qi-Xiong Qin Xue-Min Cheng li-Zhi Lu Yun-Fei Wei Da-Cheng Wang Hai-Hua li guo-hui li Hong-Bin liang Sheng-Yu li li Chen Zhi-Jian liang Department of Neurology The First Affiliated Hospital of Guangxi Medical University Department of Neurology The Second Affiliated Hospital of Guangxi Medical University Department of Neurology The Ninth Affiliated Hospital of Guangxi Medical University Department of Neurology Fusui County People’s Hospital Department of Neurology Wuzhou Red Cross Hospital Department of Neurology Cenxi People’s Hospital Department of Neurology Wuming County People’s Hospital

AIM To investigate the specific biomarkers and potential pathogenesis of colorectal cancer-related ischemic stroke(CRCIS).METHODS A retrospective study was conducted on CRCIS patients(colorectal cancer patients with ischemic stroke without conventional stroke risk factors) registered at seven centers between January 2007 and December 2017. Clinical data and laboratory and imaging findings were compared with age-and sex-matched patients with colorectal cancer(CRC) without ischemic stroke that were admitted to the same hospital during the same period. Univariate and multivariate analyses were performed to analyze the independent risk factors for CRCIS. A receiver operator characteristic curve was configured to calculate the optimal cut-off value of the products of the independent risk factors for CRCIS. RESULTS A total of 114 CRCIS patients and 114 CRC patients were included. Multiple lesions in multiple vascular territories were common in CRCIS patients(71, 62.28%). The levels of plasma D-dimer, carcinoembryonic antigen(CEA), cancer antigen 125, and neutrophil count were significantly higher in CRCIS patients than in CRC patients. Multiple logistic regression analysis revealed that plasma D-dimer levels [odds ratio(OR) = 1.002, 95% confidence interval(CI): 1.001-1.003, P lity induced by elevated CEA and neutrophils may be an important cause of CRCIS. The CRCIS index, which serves as a biomarker of CRCIS, needs further study.

关键词： Colorectal cancer Ischemic stroke Biomarker Pathogenesis

Quantum control based on three forms of Lyapunov functions

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Chinese Physics B 2024年第4期33卷 216-222页

作者：俞国慧杨洪礼 College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

This paper introduces the quantum control of Lyapunov functions based on the state distance, the mean of imaginary quantities and state *** this paper, the specific control laws under the three forms are *** is analyzed by the La Salle invariance principle and the numerical simulation is carried out in a 2D test *** calculation process for the Lyapunov function is based on a combination of the average of virtual mechanical quantities, the particle swarm algorithm and a simulated annealing ***, a unified form of the control laws under the three forms is given.

关键词： quantum system Lyapunov function particle swarm optimization simulated annealing algorithms quantum control