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Deep genome skimming reveals the hybrid origin of Pseudosasa gracilis (Poaceae: Bambusoideae)

Plant Diversity 2024年第3期46卷 344-352页

作者： Xiang-Zhou hu Cen guo Sheng-Yuan Qin De-Zhu Li Zhen-hua guo Germplasm Bank of Wild Species Kunming Institute of BotanyChinese Academy of SciencesKunmingYunnan 650201China University of Chinese Academy of Sciences Beijing 100049China

Pseudosasa gracilis(Poaceae:Bambusoideae)is a temperate woody bamboo species endemic to Southcentral China with a narrow *** phylogenetic studies revealed an unexpected,isolated phylogenetic position of *** we conducted phylogenomic analysis by sampling populations of *** and its sympatric species *** and Sinosasa polytricha reflecting different genomic signals,by deep genome *** molecular evidence from chloroplast genes and genome-wide SNPs,we deciphered the phylogenetic relationships of *** plastid and nuclear data indicate that *** is more closely related to Sinosasa,which is discordant with the taxonomic *** further explore this molecular-morphological conflict,we screened 411“perfect-copy”syntenic genes to reconstruct phylogenies using both the concatenation and coalescent *** observed extensive discordance between gene trees and the putative species tree.A significant hybridization event was detected based on 411 genes from the D subgenome,showing *** was a hybrid descendant between Sinosasa longiligulata and ***,with 63.56%and 36.44%inheritance probabilities of each ***,introgression events were detected in the C subgenome between *** and *** in the same distribution *** findings suggest that sympatric hybridization and introgression play a crucial role in the origin of *** providing an empirical example of bamboo of hybrid origin using comprehensive analyses based on genomic data from different inheritance systems and morphological characters,our study represents a step forward in understanding of reticulate evolution of bamboos.

关键词： Phylogenomics Hybridization Introgression Pseudosasa gracilis Pseudosasa Sinosasa

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Bioinspired coacervate-based bioinks for construction of multiscale tissue engineering scaffolds

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Nano Research 2024年第9期17卷 8209-8219页

作者： Zhongwei guo Shiqiang Zhang Yilin guo Jingjing Xia Xiao Wu Hao hu Rongcheng hu Fangli huang Qiulei Gao Chun Liu Jingjiang Qiu Wei Sun School of Mechanics and Safety Engineering Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering and Mechanics Tsinghua UniversityBeijing 100084China Precision Medicine Institute Guangdong Provincial Key Laboratory of Orthopedics and TraumatologyThe First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080China Department of Mechanical Engineering Drexel UniversityPhiladelphiaPA 19104USA

Engineering hydrogels that resemble biological tissues of various lengths via conventional fabrication techniques remains ***-dimensional(3D)bioprinting has emerged as an advanced approach for constructing complex biomimetic 3D architectures,which are currently restricted by the limited number of available bioinks with high printability,biomimicry,biocompatibility,and proper mechanical *** by ubiquitous coacervation phenomena in biology,we present a unique mineral-biopolymer coacervation strategy that enables the hierarchical assembly of nanoclay and recombinant human collagen(RHC).This system was observed to undergo a coacervation transition(liquid‒liquid phase separation)*** formed dense phase separated from its supernatant is the coacervate of clay-RHC-rich complexes,where polymer chains are sandwiched between silicate *** dynamics simulation was first used to verify and explore the coacervation ***,the coacervates were demonstrated to be potential bioinks that exhibited excellent self-supporting and shear-thinning viscoelastic *** extrusion-based printing,the versatility of the bioink was demonstrated by reconstructing the key features of several biological tissues,including multilayered lattice,vascular,nose,and ear-like structures,without the need for precrosslinking operations or support ***,the printed scaffolds were cytocompatible,elicited minimal inflammatory responses,and promoted bone regeneration in calvarial defects.

关键词： bioinks coacervation mineral-biopolymer nanoclay tissue engineering scaffold

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Dynamics of the spatiotemporal velocity of glaciers on the eastern slope of Mount Gongga,China,under climate change

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Advances in Climate Change Research 2024年第3期15卷 490-499页

作者： Yin fu Bo ZHANG Qiao LIU guo-Xiang LIU Rui ZHANG Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610299China Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengdu 611756China

The quantitative assessment of glacier flow velocity dynamics plays a pivotal role in understanding its response mechanisms concerning climate *** work provides a systematic quantitative assessment of the deceleration status of glaciers in this region by investigating the motion evolution of typical glaciers in Mount Gongga in recent years,thereby revealing the seasonal dynamics and inter-annual evolution over an extensive time *** used the optical flow-small baseline subset(OF-SBAS)method to compute the time-series velocities of the Hai-luogou Glacier and the Mozigou Glacier using 178 archived Sentinel-1 satellite synthetic aperture radar(SAR)images from 2014 to *** findings revealed a prominent seasonal pattern in glacier motion,characterised by cyclic variations in velocity from cold to warm ***,we identified variations in velocities across distinct regions of the glacier surface,underscored by the lag in the peak time node of glacier flow with increasing *** pattern may have been determined by a combination of internal and external factors,including mass accumulation and ablation-driven subglacial drainage,as well as the glacier geomorphological ***,during 2015-2021,the glaciers on the eastern slope of Mount Gongga exhibited an overarching trend of ***,the ablation area of the Hailuogou Glacier recorded the most substantial deceleration,exceeding 8%per *** study underscores the efficacy of the OF-SBAS method in extracting long-term glacier *** work also establishes a robust foundation for the analysis of spatiotemporal fluctuations in glacier movement within the context of climate warming.

关键词： Monsoonal temperate glaciers Synthetic aperture radar(SAR) Glacier movement Hailuogou glacier Mozigou glacier Optical flow-small baseline subset(OF-SBAS)

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Metallic Sb-stabilized porous silicon with stable SEI and high electron/ion conductivity boosting lithium-ion storage performance

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Rare Metals 2024年第9期43卷 4234-4242页

作者： Jia-guo Deng Hao-Qin Feng Yu-Long Xu Si-Guang guo Jian-Ping Li Kai-fu huo Ji-Jiang fu Biao Gao Pual-K.Chu The State Key Laboratory of Refractories and Metallurgy and Institute of Advanced Materials and Nanotechnology Wuhan University of Science and Technology Wuhan National Laboratory for Optoelectronics (WNLO) School of Optical and Electronic InformationHuazhong University of Science and Technology Department of Physics Department of Materials Science & Engineeringand Department of Biomedical EngineeringCity University of Hong Kong

Silicon （Si） has mild discharge potential and high theoretical capacity,making it a highly desirable material for lithium-ion batteries （LIBs）.Nevertheless,the excessive volume expansion,poor ion/electron conductiv ity and unstable solid electrolyte interface （SEI） hinde practical application to ***,the metallic antimony（Sb） stabilized porous Si （SiDSb） composite was prepared by magnesiothermic reduction of Sb2O3and Mg2Si and chemical etching to remove the by-product of *** highly conductive Sb nanodots embedded in the Si liga ments promote not only the formation of conductive and stable LiF-rich SEI,but also the electron/ion transpor ability of *** to the outstanding bulk/interface stability,excellent conductivity,as well as ideal porous structure,the SiDSb electrode demonstrates a capacity of820 mAh·g-1after undergoing 320 turns at 1000 mA·***,it exhibits a stable capacity of 675 m Ah·g-1when tested at a higher current density of 5000 m A·*** results reveal a viable solution to solve three problems at the same time,namely the poor conductivity,inferior SEI and excessive volume expansion of Si,boding well for the design of Si-based materials for high-energy LIBs.

关键词： Anodes Antimony Lithium-ion batteries Silicon Solid electrolyte interphase

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Improving the value of molecular testing:current status and opportunities in colorectal cancer precision medicine

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Cancer Biology & Medicine 2024年第1期21卷 21-28页

作者： Haiyun Li Linwei guo Chenchen Wang Xin hu Ye Xu Department of Colorectal Surgery Fudan University Shanghai Cancer CenterShanghai 200032China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai 200032China Department of Gastrointestinal Medical Oncology Fudan University Shanghai Cancer CenterShanghai 200032China Precision Cancer Medical Center Affiliated with fudan University Shanghai Cancer Center Shanghai 201315China

Colorectal cancer(CRC)is the second leading cause of cancer-related deaths *** radical resection with adjuvant chemotherapy remains the primary treatment choice for CRC,but the 5-year postoperative survival rate is only approximately 60%,and approximately one-third of patients with CRC experience recurrence within 2 years of ***,the transformation of high-throughput sequencing has accelerated the development of precision *** example,KRAS mutations indicate resistance to anti-epidermal growth factor receptor(EGFR)-targeted therapies in ***,molecular-guided individualized therapy has brought new promise in major clinical areas and challenges,such as novel biomarkers predicting sensitivity and resistance to immunotherapy for microsatellite stable(MSS)CRC.

关键词： cancer chemotherapy colorectal

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ATSSC:An Attack Tolerant System in Serverless Computing

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China Communications 2024年第6期21卷 192-205页

作者： Zhang Shuai guo Yunfei hu Hongchao Liu Wenyan Wang Yawen Information Engineering University Zhengzhou 450002China

Serverless computing is a promising paradigm in cloud computing that greatly simplifies cloud *** serverless computing,developers only provide function code to serverless platform,and these functions are invoked by its driven ***,security threats in serverless computing such as vulnerability-based security threats have become the pain point hindering its wide *** ideas in proactive defense such as redundancy,diversity and dynamic provide promising approaches to protect against ***,these security technologies are mostly applied to serverless platform based on“stacked”mode,as they are designed independent with serverless *** lack of security consideration in the initial design makes it especially challenging to achieve the all life cycle protection for serverless application with limited *** this paper,we present ATSSC,a proactive defense enabled attack tolerant serverless *** integrates the characteristic of redundancy,diversity and dynamic into serverless seamless to achieve high-level security and ***,ATSSC constructs multiple diverse function replicas to process the driven events and performs cross-validation to verify the *** order to create diverse function replicas,both software diversity and environment diversity are ***,a dynamic function refresh strategy is proposed to keep the clean state of serverless *** implement ATSSC based on Kubernetes and *** and experimental results demonstrate that ATSSC can effectively protect serverless computing against cyberattacks with acceptable costs.

关键词： active defense attack tolerant cloud computing security serverless computing

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Accurate and efficient remaining useful life prediction of batteries enabled by physics-informed machine learning

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Journal of Energy Chemistry 2024年第4期91卷 512-521页

作者： Liang Ma Jinpeng Tian Tieling Zhang Qinghua guo Chunsheng hu School of Mechanical MaterialsMechatronic and Biomedical EngineeringUniversity of WollongongWollongongNSW 2522Australia Department of Electrical and Electronic Engineering and Research Centre for Grid Modernization The Hong Kong Polytechnic UniversityKowloonHong Kong 999077China School of Electrical Computer and Telecommunications EngineeringUniversity of WollongongWollongongNSW 2522Australia School of Advanced Interdisciplinary Studies Ningxia UniversityYinchuan 750000NingxiaChina

The safe and reliable operation of lithium-ion batteries necessitates the accurate prediction of remaining useful life(RUL).However,this task is challenging due to the diverse ageing mechanisms,various operating conditions,and limited measured *** data-driven methods are perceived as a promising solution,they ignore intrinsic battery physics,leading to compromised accuracy,low efficiency,and low *** response,this study integrates domain knowledge into deep learning to enhance the RUL prediction *** demonstrate accurate RUL prediction using only a single charging ***,a generalisable physics-based model is developed to extract ageing-correlated parameters that can describe and explain battery degradation from battery charging *** parameters inform a deep neural network(DNN)to predict RUL with high accuracy and *** trained model is validated under 3 types of batteries working under 7 conditions,considering fully charged and partially charged *** data from one cycle only,the proposed method achieves a root mean squared error(RMSE)of 11.42 cycles and a mean absolute relative error(MARE)of 3.19%on average,which are over45%and 44%lower compared to the two state-of-the-art data-driven methods,*** its accuracy,the proposed method also outperforms existing methods in terms of efficiency,input burden,and *** inherent relationship between the model parameters and the battery degradation mechanism is further revealed,substantiating the intrinsic superiority of the proposed method.

关键词： Lithium-ion batteries Remaining useful life Physics-informed machine learning

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Enhanced Strength-Ductility Synergy in Submerged Friction Stir Processing ER2319 Alloy Manufactured by Wire-Arc Additive Manufacturing via Creating Ultrafine Microstructure

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Acta Metallurgica Sinica(English Letters) 2024年第5期37卷 793-807页

作者： Jinpeng hu Tao Sun fujun Cao Yifu Shen Zhiyuan Yang Chan guo College of Materials Science and Technology Nanjing University of Aeronautics and Astronautics(NUAA)Nanjing 210016China

Submerged friction stir processing(SFSP)with flowing water was employed to alleviate the porosities and coarse-grained structure introduced by wire-arc *** a result,uniform and ultrafine grained(UFG)structure with average grain size of 0.83μm was achieved with the help of sharply reduced heat input and holding time at elevated *** optimized UFG structure enabled a superior combination of strength and ductility with high ultimate tensile strength and elongation of 273.17 MPa and 15.39%.Specifically,grain refinement strengthening and decentralized θ(Al_(2)Cu)phase in the sample subjected to SFSP made great contributions to the enhanced *** addition,the decrease in residual stresses and removal of pores substantially enhance the *** rates of cooling and low temperature cycling,which are facilitated by the water-cooling environment throughout the machining process,are vital in obtaining superior *** work provides a new method for developing a uniform and UFG structure with excellent mechanical properties.

关键词： Submerged friction stir processing Wire-arc additive manufacturing Al-Cu alloy Residual stress Strengthening and toughening mechanism Ultrafine grained microstructure

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Space truss construction modeling based on on-orbit assembly motion feature

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Chinese Journal of Aeronautics 2024年第3期37卷 365-379页

作者： Changjie ZHAO Weizhong guo Meng CHEN Jiaxing hu Youcheng HAN Rongfu LIN State Key Lab of Mechanical System and Vibration Shanghai Jiao Tong UniversityShanghai 200240China Institute of Aerospace System Engineering Shanghai Shanghai 201109China

More space truss construction has been planned to develop and utilize space *** trusses are designed in the way of large-scale,complex,modular,and on-orbit *** meet the upcoming challenge of large-scale space infrastructure construction,it is necessary to study space truss automation design and robotic *** paper proposes an ordinal finite screw adjacency matrix model(OFSAMM),focusing on the relationship between assembly motions,to express and compute a space truss *** this model,a space truss is abstracted as a set of ordered assembly motions,each of which is recorded as a finite screw as the basic element of the truss and its *** operation of truss transformation is also derived under this ***,the truss configuration,the assembly sequence,the truss sub-assembly,the truss components,and the on-orbit assembly task can be expressed and calculated in a unified model,which is calculated and stores the truss topology and assembly with the minimum storage *** the end of this paper,we introduce how to synthesize and optimize space truss design through two *** study will help to improve design ***,it provides a theoretical basis for the automatic construction of space truss structures,especially in the next stage.

关键词： Adjacency matrix Finite screw On-orbit construction modeling Space applications Space trusses Topology design

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Fermented Lentinus edodes extract containingα-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice

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Food Science and human Wellness 2024年第4期13卷 2102-2115页

作者： Xin hu Dan Cheng Yingxia Zhang Po Li Xiaoping Wu Junsheng fu College of Life Sciences Fujian Agriculture and Forestry UniversityFuzhou 350002China Mycological Research Center Fujian Agriculture and Forestry UniversityFuzhou 350002China Shanghai Lithy One-Health Group Technology Co. Ltd.Shanghai 200235China

Autoimmune hepatitis(AIH)is a chronic inflammatory liver disease that threatens human health *** aim of this study was to detect the protective effect of a fermented Lentinus edodes extract containingα-glucan(FLA),in a concanavalin A(Con A)-induced AIH mouse model and to determine the underlying liver-protective *** results showed that compared with the model group,the level of proinflammatory cytokines in serum of FLA pretreated mice was significantly decreased,and the degree of inflammatory cell infiltration in liver,thymus and spleen was significantly *** polymerase chain reaction,immunohistochemistry,and Western blotting showed that FLA pre-treatment inhibited the Con A-induced apoptosis of hepatocytes by down-regulating the expression of BAX and up-regulating the expression of *** research found that FLA may improve liver injury in mice by activating NRF2 signaling pathway and inhibiting TRAF6/NF-κB signaling ***,FLA may improve liver injury in mice by shifting gut microbial composition to reduce the release of inflammatory cytokines in the serum and prevent the necrosis of ***-regulation of NRF2 signaling pathway,down-regulation of TRAF6/NF-κB signaling pathway,and an increase in the relative abundance of Lactobacillus_johnsonii and Ligilactobacillus_murinus play a protective role in liver.

关键词： Autoimmune hepatitis Concanavalin A Lentinus edodes TRAF6/NF-κB NRF2

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