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线性互补方程解法在减震结构体系中的应用

上海交通大学学报 2003年第12期37卷 1919-1922页

作者：龚景海邱国志董石麟上海交通大学建筑工程与力学学院上海200030

将变分不等方程-线性互补方程解法应用于减震结构体系(空间框架、框剪结构)设置减震器的分析与计算.确定了减震器的计算模型,推导出减震结构体系的变分不等方程-线性互补方程,利用Lemke算法求解并编制了相应的程序.计算结果表明,本文的... 详细信息

将变分不等方程-线性互补方程解法应用于减震结构体系(空间框架、框剪结构)设置减震器的分析与计算.确定了减震器的计算模型,推导出减震结构体系的变分不等方程-线性互补方程,利用Lemke算法求解并编制了相应的程序.计算结果表明,本文的方法、理论及程序是正确的.

关键词：结构体系变分不等方程线性互补方程减震器

Metabolome and RNA-seq reveal discrepant metabolism and secretory metabolism profile in skeletal muscle between obese and lean pigs at different ages

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Science China Life Sciences 2025年

作者： Liu guo Junfei Xu Wenyue Zhou Sisi Chen Hanjing shi Mengmeng Han Zekun Yang Yehui Duan Weijun Pang Yulong Yin Fengna Li Laboratory of Animal Nutritional Physiology and Metabolic Process Key Laboratory of Agro-ecological Processes in Subtropical Region Institute of Subtropical Agriculture Chinese Academy of Sciences University of Chinese Academy of Sciences Laboratory of Animal Fat Deposition and Muscle Development College of Animal Science and Technology Northwest A&F University College of Advanced Agricultural Sciences University of Chinese Academy of Sciences

Metabolites and metabolism-related gene expression profiles in skeletal muscle change dramatically under obesity, aging and metabolic disease. Since obese and lean pigs are ideal models for metabolic research. Here, we compared metabolome and transcriptome of Longissimus dorsi(LD) muscle between Taoyuan black(TB, obese) and Duroc(lean) pigs at different ages. We defined the “window phase” of intramuscular fat(IMF) deposition in TB pig, which has significantly higher IMF than Duroc pig. Our results displayed discrepant lipid composition and different expression genes(DEGs) enriched in lipid metabolism, and both metabolome and transcriptome analyses revealed stronger energy expenditure and more active amino acid and protein metabolism in Duroc pig. 10 up-and 51 down-regulated biomarker metabolites with age-and breed-specificity were identified. Potential secretory metabolites, including organic acid(fumaric acid, succinate,malic acid, and gamma-aminobutyric acid), amino acid(L-lysine, and L-glutamic acid), lipid(2-hydroxyisovaleric acid, and L-carnitine) were demonstrated a significant correlation with IMF deposition. Our research highlights the huge difference of metabolic spectrum in skeletal muscle between obese and lean model and muscle-derived secretory metabolites might act as an ambassador of intercellular communication to regulate systematic metabolism.

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Interpretable Machine Learning Method for Compressive Strength Prediction and Analysis of Pure Fly Ash-based Geopolymer Concrete

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 65-78页

作者： shi Yuqiong LI Jingyi ZHANG Yang LI Li Key Laboratory of Agricultural Soil and Water Engineering in Arid and Semiarid Areas of Ministry of Education Northwest A&F Uni-versityYangling 712100China College of Water Resources and Architectural Engineering Northwest A&F UniversityYangling 712100China Chongqing Key Laboratory of Public Big Data Security Technology Chongqing 401420China Chongqing College of Mobile Communication Chongqing 401520China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina National Rail Transit Electrification and Automation Engineering Technology Research Center(Hong Kong Branch) The Hong Kong Polytechnic UniversityKowloonHung HomHong KongChina

In order to study the characteristics of pure fly ash-based geopolymer concrete(PFGC)conveniently,we used a machine learning method that can quantify the perception of characteristics to predict its compressive *** this study,505 groups of data were collected,and a new database of compressive strength of PFGC was *** order to establish an accurate prediction model of compressive strength,five different types of machine learning networks were used for comparative *** five machine learning models all showed good compressive strength prediction performance on *** them,R2,MSE,RMSE and MAE of decision tree model(DT)are 0.99,1.58,1.25,and 0.25,*** R2,MSE,RMSE and MAE of random forest model(RF)are 0.97,5.17,2.27 and 1.38,*** two models have high prediction accuracy and outstanding generalization *** order to enhance the interpretability of model decision-making,we used importance ranking to obtain the perception of machine learning model to 13 *** 13 variables include chemical composition of fly ash(SiO_(2)/Al_(2)O_(3),Si/Al),the ratio of alkaline liquid to the binder,curing temperature,curing durations inside oven,fly ash dosage,fine aggregate dosage,coarse aggregate dosage,extra water dosage and sodium hydroxide *** temperature,specimen ages and curing durations inside oven have the greatest influence on the prediction results,indicating that curing conditions have more prominent influence on the compressive strength of PFGC than ordinary Portland cement *** importance of curing conditions of PFGC even exceeds that of the concrete mix proportion,due to the low reactivity of pure fly ash.

关键词： machine learning pure fly ash geopolymer compressive strength feature perception

A versatile synthetic strategy towards rare earth based metal-organic frameworks

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Science China Chemistry 2025年

作者： Quan shi Yun-Hao Xu Ming-Hui Chen Peng Zhao Wen-Bo Deng Ji Xiong Kai guo Ya-Qing Feng Bao Zhang School of Chemical Engineering and Technology Tianjin University Tianjin Collaborative Innovation Center of Chemical Science and Engineering Guangdong Laboratory Chemistry & Fine Chemical Industry Jieyang Center

Rare earth metal-organic frameworks (RE-MOFs) have drawn wide attention owing to diverse network structures and various application ***,due to the unpredictable formation of the nodes,it is still challenging to design novel RE-MOFs.A novel versatile strategy was developed employing a RE-acetate complex (RE2(CH3COO)6·4H2O) as a precursor to construct RE-MOFs.2D RE-MOFs (RE-DBP) and 3D RE-MOFs (RE-TCPP) could be obtained by using dicarboxylic porphyrin ligands H2DBP and tetracarboxylic porphyrin ligands H2TCPP,*** RE-MOFs were further synthesized to verify the universality of the *** crystalline RE-MOFs could also be prepared at room temperature via the developed strategy,which could significantly promote large-scale preparation and practical application of *** proof of the concept,the performance of porphyrin-based RE-MOFs was investigated in the photocatalytic cycloaddition of CO2with *** the RE-DBP(Co) MOFs,Tb-DBP(Co) exhibited the best photocatalytic performance,which was also greater than that of the corresponding 3D MOF Tb-TCPP(Co) due to the optimal 2D structure and thus the accelerated photogenerated charge separation and transfer *** work not only provides a novel versatile strategy to design and develop RE-MOFs,but also proposes a promising approach for the potential bulk production of RE-MOFs at room temperature.

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液熏斑点叉尾鱼肉中熏液渗透及苯并(a)芘检测

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食品工业科技 2009年第12期30卷 145-148页

作者：钟威胡雪梅万刚张龙兵过世东江南大学食品学院江苏无锡214122 通威成都水产食品有限公司四川成都611430

采用修正吉布斯法和盐酸羟胺法对液熏前后熏液中酚类物质和羰基化合物含量进行比较,采用高效液相色谱法对烟熏鱼和液熏鮰鱼中苯并(a)芘含量进行检测。结果表明,鱼肉液熏处理后,羰基化合物的渗透与鱼肉烟熏色泽之间具有显著相关性(p>0·... 详细信息

采用修正吉布斯法和盐酸羟胺法对液熏前后熏液中酚类物质和羰基化合物含量进行比较,采用高效液相色谱法对烟熏鱼和液熏鮰鱼中苯并(a)芘含量进行检测。结果表明,鱼肉液熏处理后,羰基化合物的渗透与鱼肉烟熏色泽之间具有显著相关性(p>0·9),酚类物质的渗透,对鱼肉具有很好的抗氧化作用。液熏鮰鱼时,取熏液质量浓度为3%,熏制2～6h为宜。液熏鮰鱼中苯并(a)芘含量为1·00μg/kg,符合国际食品卫生要求。

关键词：斑点叉尾鲴液熏渗透抗氧化苯并(a)芘

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青藏高原臭氧谷的分布及其与太阳辐射的关系

高原气象 2017年第5期36卷 1201-1208页

作者：焦铂洋苏昱丞郭胜利郭栋施春华李婧媛苍中亚傅帅空间天气研究所/南京信息工程大学数学与统计学院南京210044 福建省气象培训中心福州350007 南京信息工程大学气象灾害教育部重点实验室/气候与环境变化国际合作联合实验室/气象灾害预报预警与评估协同创新中心南京210044 中国科学院国家天文台北京100012

使用2005—2015年夏季Aura卫星微波临边探测器(MLS)逐日臭氧观测资料,讨论了夏季青藏高原臭氧低值区的三维分布。研究发现,青藏高原臭氧不仅在对流层顶附近存在着臭氧低值区,而且在平流层上层(20~1 hPa)也存在显著的低值区。高原区上空... 详细信息

使用2005—2015年夏季Aura卫星微波临边探测器(MLS)逐日臭氧观测资料,讨论了夏季青藏高原臭氧低值区的三维分布。研究发现,青藏高原臭氧不仅在对流层顶附近存在着臭氧低值区,而且在平流层上层(20~1 hPa)也存在显著的低值区。高原区上空50%以上的臭氧存在于21.5~1.2 hPa的范围内,因此平流层上层高原臭氧低值对高原臭氧谷来说也很重要。使用合成分析法对MLS夏季北半球昼夜臭氧进行研究,结果表明该低值区仅存在于白天。根据高原区平流层上层臭氧模拟数据的集合经验模态分解,得到IMF4的平均频率为0.09,平均周期为11.1年,正好对应太阳活动最强的周期。说明太阳辐射是影响高原平流层上层臭氧低值中心的一个因素。

关键词：青藏高原平流层中上层臭氧低值中心太阳辐射

温室鳖与池塘鳖肌肉和裙边挥发性风味成分的研究

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食品科学 2008年第2期29卷 110-115页

作者：方燕袁信华过世东王利平吴胜芳江南大学食品学院食品科学与安全教育部重点实验室江苏无锡214122 江南大学分析测试中心江苏无锡214122

采用顶空固相微萃取(HS-SPME)和气质联用技术研究了温室鳖、池塘鳖肌肉和裙边的挥发性风味成分。共鉴定出113种化合物,温室鳖肌肉含59种,池塘鳖肌肉含34种,温室鳖裙边含60种,池塘鳖裙边含50种。113种化合物中含芳香族化合物23种、醛类2... 详细信息

采用顶空固相微萃取(HS-SPME)和气质联用技术研究了温室鳖、池塘鳖肌肉和裙边的挥发性风味成分。共鉴定出113种化合物,温室鳖肌肉含59种,池塘鳖肌肉含34种,温室鳖裙边含60种,池塘鳖裙边含50种。113种化合物中含芳香族化合物23种、醛类23种、醇类19种、酮类12种、N、S化合物10种、烷烃类10种、酯类8种、酸类5种、呋喃类化合物3种。

关键词：中华鳖挥发性风味化合物顶空固相微萃取气相色谱质谱联用

明胶与阿拉伯胶复合凝聚法制备脂肪替代品的研究

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食品科学 2009年第8期30卷 124-127页

作者：刘贺朱丹实刘丽萍陈忠川徐学明过世东金征宇渤海大学生物与食品科学学院辽宁锦州121000 食品科学与技术国家重点实验室江苏无锡214122 江南大学食品学院江苏无锡214122

随着人们对高油脂食品对健康影响的认识,脂肪替代品开发的意义越来越大。本实验以明胶和阿拉伯胶为主要原料通过复合凝聚法制备脂肪替代品(FS),得到FS产率高达4.93的生产工艺:pH4.25,明胶溶液与阿拉伯胶溶液配比1:1、搅拌温度50℃、静... 详细信息

随着人们对高油脂食品对健康影响的认识,脂肪替代品开发的意义越来越大。本实验以明胶和阿拉伯胶为主要原料通过复合凝聚法制备脂肪替代品(FS),得到FS产率高达4.93的生产工艺:pH4.25,明胶溶液与阿拉伯胶溶液配比1:1、搅拌温度50℃、静置时间为0.5h、溶质浓度2%、搅拌速度100r/min。产品的外观类似油脂,体积平均粒径在10μm左右,满足脂肪替代品特性要求。

关键词：明胶阿拉伯胶复合凝聚脂肪替代品

circT P63-N suppresses the proliferation and metastasis of nasopharyngeal carcinoma via engaging with HSP90AB1 to modulate the YAP1/Hippo signaling pathway

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Science China Life Sciences 2025年

作者： Dan Wang Sicheng Zuo Junshang Ge Hongke Qu Jie Wu Na Yi Lei shi Yumin Wang Yongzhen Mo Chunmei Fan Yi He Pan Chen Ming Zhou Bo Xiang Wei Xiong Wenjia guo Zhaoyang Zeng Can guo NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education Cancer Research Institute and School of Basic Medicine Sciences Central South University Furong Laboratory Cancer Research Institute Affiliated Cancer Hospital of Xinjiang Medical University Xinjiang Key Laboratory of Translational Biomedical Engineering

Circular RNAs(circRNAs) play pivotal roles in the development and progression of various diseases, including malignant tumors. However,the biological functions and the underlying mechanisms of many circRNAs remain elusive. In this study, we identified a novel circRNA,circTP63-N, generated through the splicing of exons 2–4 of the TP63 gene in nasopharyngeal carcinoma(NPC). circTP63-N was found to be downregulated in clinical samples of NPC. Both in vitro and in vivo experiments unequivocally demonstrated that circTP63-N inhibits the proliferation and metastasis of NPC cells. Further investigations revealed that circTP63-N interacted with the HSP90AB1 protein, leading to the recruitment of LATS/YAP1 proteins. This, in turn, induced phosphorylation and ubiquitination-dependent degradation of YAP1, resulting in reduced nuclear translocation of YAP1 and inhibition of the transcriptional activation of downstream oncogenic genes, including INHBA, MMP3, and CCNE2. Our findings highlight the identification of circTP63-N, a novel circRNA encoded by an important tumor-relevant gene TP63 and elucidate its molecular mechanism as a tumor suppressor in NPC. These insights offer novel potential molecular markers and therapeutic targets for the clinical diagnosis and treatment of NPC.

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