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The interventional effect of Polygonatum cyrtonema Hua polysaccharide on atherosclerosis in mice of different sexes

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Food Science and Human Wellness 2024年第1期13卷 370-380页

作者： Anjun guo Xueying Li Lihua Pan qia.gming Li Jianping Luo Xueqia.g zha Engineering Research Centre of Bioprocess of Ministry of Education Hefei University of TechnologyHefei 230009China School of Food and Biological Engineering Hefei University of TechnologyHefei 230009China Key Laboratory of Metabolism and Regulation for Major Disease of Anhui Higher Education Institutes Hefei University of TechnologyHefei 230009China

In the present study,we investigated the intervention effects of a purified Polygonatum cyrtonema polysaccharide(PCP)on high-fat diet(HFD)-induced atherosclerosis in male and female LDLr-/-*** showed that HFD caused severe dyslipidemia,atherosclerotic lesions,oxidative damages and inflammation in male and female mice,and these effects seemed to be more pronounced in males than in ***,the above variations could be dose-dependently reversed by PCP treatment,and the intervention effects on males were greater than those on *** factor kappa-B(NF-κB),mitogen-activated protein kinase(MAPKs)and protein kinase B(Akt)are 3 pivotal signaling pathways mediating the development of ***,PCP was also found to significantly decrease the phosphorylation of p65,p38,extracellular-regulated kinase 1/2(ERK1/2)and Akt,and increase the protein expression of inhibitor of NF-κB(IκB)in the aortas of male and female mice induced by *** together,these findings indicated that PCP could be effective for the prevention of atherosclerosis,and the intervention effect of PCP on male mice was more obvious than that of female mice.

关键词： Polygonatum cyrtonema polysaccharide Anti-atherosclerosis Sex

Effect of nucleating agents on the electrical properties of cross-linked polyethylene under tensile stress

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High Voltage 2024年第2期9卷 429-439页

作者： Yunqi Xing Jiahao Liu Jingang Su Junwei zha.guochang Li Ze guo Xiaozhen zhao Mengjia Feng State Key Laboratory of Reliability and Intelligence of Electrical Equipment Hebei University of TechnologyTianjinChina Electric Power Research Institute of State grid Hebei Electric Power Supply Co. Ltd.ShijiazhuangChina Beijing Advanced Innovation Center for Materials genome Engineering School of Chemistry and Biological EngineeringUniversity of Science&Technology BeijingBeijingChina Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdaoChina

During the operation of high-voltage cables,external stress and residual stress can affect the aggregated structure of insulating materials and lead to significant deterioration in their electrical *** investigate the evolution characteristics of the electrical properties of cross-linked polyethylene(XLPE)under mechanical stress,this paper ex-plains the relationship between the aggregated structure of XLPE and its electrical properties and proposes a method for improving insulation performance under me-chanical *** results show that metallocene polyethylene used as a nucleating agent can promote crystallisation through heterogeneous nucleation and increase Young's modulus by non-uniform nucleation,increasing crystallinity and reducing interplanar spacing,resulting in more complete crystal forms and reduced damage to the aggregated structure during the tensile *** nucleating agent modification,the XLPE crystallisation becomes more uniform,and interfacial adhesion forces *** weakened interface damage process between the amorphous and crystalline regions under tensile stress effectively inhibits the process of molecular chain polarisation turning and reduces trap *** modified XLPE crystal structure shows a tendency towards densification and enhanced molecular chain interactions,which can reduce the damage to the aggregated structure under tensile stress,while the reduced free volume inside the material and the shortened average free path of carriers can weaken the damage of high-energy electrons to molecular chains,thereby inhibiting the process of electrical tree *** results show that nucleating agents have great potential for maintaining the stable operation of XLPE cables under mechanical stress.

关键词： stress electrical damage

The coupling control of biological precursors and environmental factors onβ-carotane enrichment in alkaline lacustrine source rocks:A case study from the Fengcheng formation in the western Junggar Basin,NW China

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Petroleum Science 2024年第2期21卷 836-854页

作者： Mao-guo Hou Ming zha Hua Liu Hai-Lei Liu Jiang-Xiu Qu Ablimit Imin Xiu-Jian Ding Zhong-Fa Jiang School of geosciences China University of PetroleumQingdaoShandong266580China Research Institute of Exploration and Development Xinjiang Petroleum Administration BureauKaramayXinjiang834000China

The organic-rich mudstones and dolostones of the Permian Fengcheng Formation(Fm.)are typically alkaline lacustrine source rocks,which are typified by impressively abundantβ-*** β-carotane has been well acknowledged as an effective indicator of biological sources or depositional ***,the specific biological sources of β-carotane and the coupling control of biological sources and environmental factors on the enrichment of β-carotane in the Fengcheng *** *** on a comprehensive investigation of the bulk,molecular geochemistry,and organic petrology of sedimentary rocks and the biochemistry of phytoplankton in modern alkaline lakes,we proposed a new understanding of the biological precursors of β-carotane and elucidated the enrichment mechanism of β-carotane in the Fengcheng *** results show that the biological precursors crucially control the enrichment of β-carotane in the Fengcheng *** haloalkaliphilic cyanobacteria are the primary biological sources of β-carotane,which is suggested by a good positive correlation between the 2-methylhopane index,7-+8-methyl heptadecanes/C_(max),C_(29%),and β-carotane/C_(max)in sedimentary rocks and the predominance of cyanobacteria with abundantβ-carotene in modern alkaline *** enrichment of β-carotane requires the reducing condition,and the paleoredox state that affects the enrichment of β-carotane appears to have a *** paleoclimate conditions do not considerably impact the enrichment of β-carotane,but they have some influence on the water's paleosalinity by affecting evaporation and *** it does not directly affect the enrichment of β-carotane in the Fengcheng Fm.,paleosalinity does have an impact on the cyanobacterial precursor supply and the preservation conditions.

关键词： β-carotane enrichment Cyanobacterial input Environmental impact Alkaline lacustrine source rocks The Fengcheng formation

风屏障透风率对强风作用下重载铁路刚构-连续梁车桥耦合振动响应的影响

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中国铁道科学 2024年第4期45卷 57-65页

作者：郭向荣查万祺何旭辉中南大学土木工程学院湖南长沙410075

为探究风屏障透风率对强风作用下重载铁路刚构-连续梁车桥耦合振动的影响,先通过节段模型风洞试验获取桥上设置0%,20%,40%,60%和无风屏障5种不同透风率风屏障时车桥系统的三分力系数,再根据弹性系统动力学总势能不变原理建立风-车-桥耦... 详细信息

为探究风屏障透风率对强风作用下重载铁路刚构-连续梁车桥耦合振动的影响,先通过节段模型风洞试验获取桥上设置0%,20%,40%,60%和无风屏障5种不同透风率风屏障时车桥系统的三分力系数,再根据弹性系统动力学总势能不变原理建立风-车-桥耦合振动仿真计算分析模型,对不同车速下重载货运列车通过设置不同透风率风屏障刚构-连续梁桥开展风-车-桥系统动力学仿真计算与分析研究。结果表明:在列车上桥初期,桥梁横向位移峰值随透风率的增大而明显减小,而当列车运行趋于满布桥梁时,桥梁的横向位移峰值随透风率的增大变化不明显;列车的动力响应峰值随风屏障透风率的增大而增大,相比于满载编组列车,空载和轻重混编编组列车的动力响应对风屏障透风率的变化更加敏感。综合桥梁动力响应和列车走行安全性评价指标(脱轨系数和轮重减载率),该桥梁应设置40%透风率的风屏障。

关键词：重载铁路刚构-连续梁桥风屏障透风率风车桥耦合振动行车安全

“双碳”目标下重污染企业漂绿与政府规制的动态博弈分析

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西安科技大学学报 2024年第1期44卷 194-202页

作者：张洽郭帆刘志明西安科技大学管理学院陕西西安710054

为探讨“双碳”目标下对重污染企业漂绿行为的治理,运用动态博弈分析法构建了政府干预与不干预、企业实施漂绿行为与不实施漂绿行为,以及政府干预情形下,补助、补助+激励、补助+激励+惩罚模式下的两方3阶段模型。结果表明:政府的行为能... 详细信息

为探讨“双碳”目标下对重污染企业漂绿行为的治理,运用动态博弈分析法构建了政府干预与不干预、企业实施漂绿行为与不实施漂绿行为,以及政府干预情形下,补助、补助+激励、补助+激励+惩罚模式下的两方3阶段模型。结果表明:政府的行为能显著影响企业的行为,同时也会受到企业行为的影响,对于政府来说,是否会采取干预的策略,主要与自由市场下漂绿治理程度,以及实施干预措施所要付出的成本和干预带来的总社会效益有关;对于企业来说,是否会实施漂绿取决于不漂绿所要遭受的总损失和参与成本之和与带来利益的比较。为了更好地实现“双碳”目标及可持续高质量发展,企业应避免机会主义的寻租行为,积极承担社会责任,践行低碳绿色转型;政府应优化外部环境和完善法律法规,分阶段、分措施治理漂绿行为。

关键词：经济计划与管理重污染企业动态博弈漂绿政府规制

人工智能三维规划系统在全髋关节置换中的准确性及其影响因素

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中国组织工程研究 2024年第12期28卷 1863-1868页

作者：张凯郭卓涛马桥桥查国春郭开今徐州医科大学江苏省徐州市221000 徐州医科大学附属医院骨科江苏省徐州市221000

背景:人工智能三维规划系统能够自动建立三维模型并生成规划方案,但其预测假体型号的准确性尚未得到充分验证。目的:探讨人工智能三维规划系统在全髋关节置换前预测假体型号的准确性及对临床预后的影响,并进一步分析影响规划准确性的危... 详细信息

背景:人工智能三维规划系统能够自动建立三维模型并生成规划方案,但其预测假体型号的准确性尚未得到充分验证。目的:探讨人工智能三维规划系统在全髋关节置换前预测假体型号的准确性及对临床预后的影响,并进一步分析影响规划准确性的危险因素。方法:前瞻性收集2021年1月至2022年6月在徐州医科大学附属医院骨科接受单侧初次全髋关节置换患者的临床资料,随机分为人工智能组(n=80)和传统模板组(n=79)。对比两组术中使用假体与术前规划假体的匹配情况,记录术后随访Harris功能评分、双下肢不等长、脱位和假体松动等并发症的发生情况,采用单因素及多因素Logistic回归分析来探究人口统计学指标、术前诊断、Dorr分型对股骨柄规划准确性的影响。结果与结论:①人工智能组髋臼侧、股骨侧假体完全符合率分别为50%(40/80)、55%(44/80),传统模板组为34%(27/79)、37%(29/79),组间差异有显著性意义(P0.05);④单因素分析结果显示,术前诊断为先天性髋关节发育不良、股骨头坏死以及Dorr B型、C型股骨对人工智能三维规划系统预测股骨假体准确率有显著影响(Pgistic回归分析显示,术前诊断为先天性髋关节发育不良(OR=18.233,95%CI:2.662-124.888)是影响人工智能三维规划系统预测股骨柄型号的独立危险因素;⑥提示人工智能三维规划系统预测假体型号较传统二维模板具有更高的准确率,且对术后并发症的发生风险和关节功能并不会造成明显的差异。由于解剖畸形和髋臼解剖位置重建,人工智能三维规划系统在先天性髋关节发育不良患者中准确率较低。

关键词：术前规划人工智能全髋关节置换股骨近端髓腔形态假体型号

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湿热力作用下粉砂质泥岩开裂特性研究

湖南大学学报（自然科学版） 2024年第1期51卷 126-136页

作者：曾铃郭雨查焕奕高乾丰黎繁卞汉兵桥梁工程安全控制教育部重点实验室(长沙理工大学) 湖南长沙410114 长沙理工大学土木工程学院湖南长沙410114 长沙理工大学交通运输工程学院湖南长沙410114

为探究湿热力作用下粉砂质泥岩的开裂特性,开展裂隙演化试验,得到湿热力单因素及多因素耦合循环作用下粉砂质泥岩的裂隙演化规律,同时利用X射线衍射、扫描电镜研究其微观结构变化特征,分析宏观和微观试验结果关联性,揭示湿热力作用下粉... 详细信息

为探究湿热力作用下粉砂质泥岩的开裂特性,开展裂隙演化试验,得到湿热力单因素及多因素耦合循环作用下粉砂质泥岩的裂隙演化规律,同时利用X射线衍射、扫描电镜研究其微观结构变化特征,分析宏观和微观试验结果关联性,揭示湿热力作用下粉砂质泥岩裂隙扩展机制.研究结果表明:粉砂质泥岩裂隙发育表现为增长-平缓趋势;在单因素循环作用中,湿度循环(浸水~烘干)最易造成粉砂质泥岩开裂,温度循环(5~60℃)次之,荷载循环(0~50 kPa)最弱;在多因素耦合循环作用中,裂隙发育程度排序为:湿热力>湿热>湿力>热力,验证了湿度循环致裂性最强的结论.湿热力耦合循环作用15次后裂隙率达0.92%,裂隙条数增至30条,平均长度延伸至60.58 mm,而平均宽度稳定在0.47 mm左右.孔隙率与裂隙率的灰关联度最大,为0.813,即微观结构变化中孔隙发育与裂隙扩展的关联程度最大.湿热力耦合循环作用中,湿度循环引起黏土矿物晶层间距变化,导致颗粒破碎、孔隙扩张形成微裂隙,温度循环使试样产生差异性热应力、水分分布,促使微裂隙发育贯通,荷载作用增加尖端应力,最终导致裂隙网络形成.

关键词：边坡工程粉砂质泥岩湿热力作用裂隙发育微观结构

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双酚A型苯酰亚胺溶解度测定及关联

应用化工 2024年第3期53卷 739-742页

作者：孙闯杨座国查美琴华东理工大学化工学院上海200237 上海化工研究院有限公司上海200062

用平衡法测定了273.15~353.15 K下双酚A型苯酰亚胺在不同溶剂中的溶解度。结果表明,随着温度的升高,苯酰亚胺溶解度增大,通过改进的Apelblat方程,λh方程和Wilson活度系数方程关联该物质的溶解度数据,相关系数分别不低于0.9880,0.9771,0... 详细信息

用平衡法测定了273.15~353.15 K下双酚A型苯酰亚胺在不同溶剂中的溶解度。结果表明,随着温度的升高,苯酰亚胺溶解度增大,通过改进的Apelblat方程,λh方程和Wilson活度系数方程关联该物质的溶解度数据,相关系数分别不低于0.9880,0.9771,0.9394,3种模型均能较好地拟合苯酰亚胺的溶解度数据,对比几种模型的拟合结果,改进的Apelblat方程拟合效果最好,其中ARD≤6.18%,RSMD≤2.39,且R^(2)≥0.9880,为结晶过程的设计提供热力学依据。

关键词：苯酰亚胺重结晶溶解度模型关联

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UUV推进器用磁耦合联轴器的设计与仿真

舰船科学技术 2024年第11期46卷 103-107页

作者：郭嘉查鸭宏温健全昆明船舶设备研究试验中心云南昆明650200 昆明电机厂有限责任公司云南昆明650228

本文研究目的是无人潜航器(Unmanned Underwater vehicle,UUV)推进器用磁耦合联轴器的设计与仿真方法,预先初选磁耦合联轴器的主要尺寸、再建立磁路近似模型,采用解析计算求得传递扭矩及隔离套上的涡流损耗值,再用低频电磁场仿真软件校... 详细信息

本文研究目的是无人潜航器(Unmanned Underwater vehicle,UUV)推进器用磁耦合联轴器的设计与仿真方法,预先初选磁耦合联轴器的主要尺寸、再建立磁路近似模型,采用解析计算求得传递扭矩及隔离套上的涡流损耗值,再用低频电磁场仿真软件校核扭矩及涡流损耗,然后经过几轮设计方案的迭代,最终使磁耦合联轴器满足UUV集成推进器的设计要求,在设计的迭代过程中同时分析了内外磁转子夹角与扭矩的关系、内外磁转子轴向长度对扭矩、涡流损耗的影响。

关键词：磁耦合隔离套传递扭矩涡流损耗