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Association of HbA1c Level with Lipid Ratio in Diabetic Patients

Journal of Pharmacy and Pharmacology 2018年第8期6卷 796-799页

作者： Lizete Klavina Beate Ulmane Lāsma Milgrāve gunta tīcmene Rīga Stradins University Dzirciema street 16 Riga LV-1007 Latvia Family doctor's practice Department of Family Medicine Druvas doktorats Druva LV-3862 Latvia

Introduction： Diabetes mellitus is a common disease in the world and the number of diabetes patients is rapidly increasing. Dyslipidemia is one of the most risk factors for cardiovascular disease which is more prevalent among adults with diabetes than in the general population. Aim： to study the correlation of diabetes patients glycated hemoglobin （HbA1c） with lipid ratios. Materials and methods： Samples were collected from 101 diabetic patients （aged 19-86 years; male 51, female 50）. Retrospective study included data such as age, gender, type of diabetes, HbA1c, total cholesterol, LDL cholesterol and triglyceride from two family medicine doctor’s practices. According to the HbA1c level, the patients were divided into three groups, group A （HbA1c 〈 7%, n = 58）, group B （7% ≤ HbA1c 〈 10%, n = 37） and group C （HbA1c ≥ 10%, n = 6）. the correlations of HbA1c with lipid ratios were analyzed. Results： In the group A the mean HbA1c was 6.1 ± 0.5%, mean age-60.6 years, total cholesterol-4.7 mmol/L, LDL-2.8 mmol/L, triglycerides-1.6 mmol/L. In the group B the mean HbA1c was 7.7 ± 0.6%, mean age-64.0 years, total cholesterol-5.7 mmol/L, LDL-3.1 mmol/L, triglycerides-2.2 mmol/L and in the group C the mean HbA1c was 11.2 ± 1.0%, mean age-48.7 years, total cholesterol-4.9 mmol/L, LDL-2.7 mmol/L, triglycerides-1.7 mmol/L. Conclusions： From all groups highest total cholesterol, LDL cholesterol, triglycerides were patients in the group B. In others two groups lipid profile changes were without any significant differences and there was no association with HbA1c.

关键词： Diabetes HbA1c total cholesterol LDL cholesterol triglycerides.

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