Association of HbA1c Level with Lipid Ratio in Diabetic Patients

作     者：Lizete Klavina Beate Ulmane Lāsma Milgrāve Gunta Tīcmene 

作者机构：Rīga Stradins University Dzirciema street 16 Riga LV-1007 Latvia Family doctor's practice Department of Family Medicine Druvas doktorats Druva LV-3862 Latvia 

出 版 物：《Journal of Pharmacy and Pharmacology》 (药剂与药理学（英文版）)

年 卷 期：2018年第6卷第8期

页      面：796-799页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Diabetes HbA1c total cholesterol LDL cholesterol triglycerides. 

摘      要：Introduction： Diabetes mellitus is a common disease in the world and the number of diabetes patients is rapidly increasing. Dyslipidemia is one of the most risk factors for cardiovascular disease which is more prevalent among adults with diabetes than in the general population. Aim： To study the correlation of diabetes patients glycated hemoglobin （HbA1c） with lipid ratios. Materials and methods： Samples were collected from 101 diabetic patients （aged 19-86 years; male 51, female 50）. Retrospective study included data such as age, gender, type of diabetes, HbA1c, total cholesterol, LDL cholesterol and triglyceride from two family medicine doctor’s practices. According to the HbA1c level, the patients were divided into three groups, group A （HbA1c 〈 7%, n = 58）, group B （7% ≤ HbA1c 〈 10%, n = 37） and group C （HbA1c ≥ 10%, n = 6）. The correlations of HbA1c with lipid ratios were analyzed. Results： In the group A the mean HbA1c was 6.1 ± 0.5%, mean age-60.6 years, total cholesterol-4.7 mmol/L, LDL-2.8 mmol/L, triglycerides-1.6 mmol/L. In the group B the mean HbA1c was 7.7 ± 0.6%, mean age-64.0 years, total cholesterol-5.7 mmol/L, LDL-3.1 mmol/L, triglycerides-2.2 mmol/L and in the group C the mean HbA1c was 11.2 ± 1.0%, mean age-48.7 years, total cholesterol-4.9 mmol/L, LDL-2.7 mmol/L, triglycerides-1.7 mmol/L. Conclusions： From all groups highest total cholesterol, LDL cholesterol, triglycerides were patients in the group B. In others two groups lipid profile changes were without any significant differences and there was no association with HbA1c.