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First case of forearm crisscross injury in children:A case report

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World Journal of Clinical Cases 2021年第25期9卷 7478-7483页

作者： Yi-Kun Jiang yan-bing Wang Chuan-Gang Peng Ji qu Dan-Kai Wu department of Orthopedics The Second Hospital of Jilin UniversityChangchun 130000Jilin ProvinceChina

BACKGROUND Forearm crisscross injury is rare in children;there is no relevant literature so *** lack experience and knowledge in treating this type of crisscross *** report a case of forearm crisscross injury in a child for the first time and analyze its *** SUMMARY An 8-year-old boy experienced pain in his left forearm when he accidentally fell while *** examination revealed swelling and deformity of the left *** performed imaging and the results revealed left radial head dislocation,left distal radial epiphyseal separation from the shaft,and interruption of the continuity of the dorsal cortex of the left distal *** and lateral X-ray films showed that the radius and ulna were crisscrossed.A diagnosis of superior radioulnar joint dislocation,left distal radial epiphyseal injury,and left distal ulnar fracture was *** unsuccessful manual reduction,we adopted a minimally invasive procedure and *** a 14-wk period of follow-up,the patient had good left upper limb function,no complaints of pain or limited range of motion,and good follow-up *** This is the first report of a child with a forearm crisscross injury in which the mechanism and the differences from adult crisscross injury are *** invasive surgery with intramedullary fixation can achieve a good therapeutic *** case provides a reference for the treatment of similar patients in the future.

关键词： Children Forearm Cross injury Fracture Case report

Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in china:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan Liu Rui-Xia Ma Xian-Bao Cao Hua Zhang Shui-Hong Zhou Wei-Hong Jiang yan Jiang Jing-Wu Sun Qin-Tai yang Xue-Zhong Li Ya-Nan Sun Li Shi Min Wang Xi-Cheng Song Fu-quan Chen Xiao-Shu Zhang Hong-quan Wei Shao-Qing Yu Dong-Dong Zhu Luo Ba Zhi-Wei Cao Xu-Ping Xiao Xin Wei Zhi-Hong Lin Feng-Hong Chen Chun-Guang Shan Guang-Ke Wang Jing Ye Shen-Hong qu Chang-Qing Zhao Zhen-Lin Wang Hua-Bin Li Feng Liu Xiao-Bo Cui Sheng-Nan Ye Zheng Liu Yu Xu Xiao Cai Wei Huang Ru-Xin Zhang Yu-Lin Zhao Guo-Dong Yu Guang-Gang Shi Mei-Ping Lu yang Shen Yu-Tong Zhao Jia-Hong Pei Shao-bing Xie Long-Gang Yu Ye-Hai Liu Shao-Wei Gu Yu-Cheng yang Lei Cheng Jian-Feng liu Graduate School of Beijing university of Chinese Medicine BeijingChina department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

鹿茸多肽介导心肌干细胞分化对终末心肌分化基因ANP和MLC-2v表达的影响

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吉林大学学报（医学版） 2018年第2期44卷 249-253页

作者：黄晓巍徐岩韩冬林贺律广富李晓华曲晓波张冰长春中医药大学中医药与生物工程研究开发中心药理实验室吉林长春130117 长春中医药大学药学院临床药学与中药药理教研室吉林长春130117 北京中医药大学中药学院临床中药系北京100102

目的:探讨鹿茸多肽介导心肌干细胞(CSC)分化对终末心肌分化基因心房钠尿肽(ANP)和心肌肌凝蛋白轻链2(MLC-2v)表达的影响,阐明其修复受损心肌的作用机制。方法:选取出生2d的雄性Wistar大鼠,提取CSC,免疫荧光鉴定CSC表面标志物c-Kit,流式... 详细信息

目的:探讨鹿茸多肽介导心肌干细胞(CSC)分化对终末心肌分化基因心房钠尿肽(ANP)和心肌肌凝蛋白轻链2(MLC-2v)表达的影响,阐明其修复受损心肌的作用机制。方法:选取出生2d的雄性Wistar大鼠,提取CSC,免疫荧光鉴定CSC表面标志物c-Kit,流式细胞术鉴定CSC纯度。以培养皿为实验单位,分为空白对照组(加等量缓冲液)、5-氮胞苷组(终浓度3μmol·L-1)、鹿茸多肽组(终浓度800mg·L-1)和联合组(3μmol·L-1 5-氮胞苷+800mg·L-1鹿茸多肽),于37℃、5%CO2培养箱中培养48h。ELISA法检测各组细胞上清液中ANP和MLC-2v表达水平,RT-PCR法检测各组细胞中ANP和MLC-2v mRNA表达水平。结果:获得纯度>95%的CSC。ELISA法检测,与空白对照组比较,5-氮胞苷组、鹿茸多肽组和联合组细胞上清中ANP和MLC-2v表达水平明显升高(P0.05)。RT-PCR法检测,与空白对照组比较,5-氮胞苷组、鹿茸多肽组和联合组ANP和MLC-2vmRNA表达水平明显升高(P<0.05)。结论:鹿茸多肽可以通过增强心肌分化基因ANP和MLC-2v表达介导CSC分化为心肌细胞,且在一定程度上减轻5-氮胞苷所致的细胞毒性。

关键词：鹿茸多肽心肌干细胞心房钠尿肽心肌肌凝蛋白轻链2

Lung-protective Ventilation in Patients with Brain Injury： A Multicenter Cross-sectional Study and questionnaire Survey in china

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Chinese Medical Journal 2016年第14期129卷 1643-1651页

作者： Xu-Ying Luo Ying-Hong Hu Xiang-Yuan Cao yan Kang Li-Ping Liu Shou-Hong Wang Rong-Guo Yu Xiang-You Yu Xia Zhang Bao-Shan Li Zeng-Xiang Ma Yi-bing Weng Heng Zhang De-Chang Chen Wei Chen Wen-Jin Chen Xiu-Mei Chen Bin Du Mei-Li Duan Jin Hu Yun-Feng Hoang Gui-Jun Jia Li-Hong Li Yu-Min Liang bing-Yu Qin Xian-Dong Wang Jian Xiong Li-Mei yan Zheng-Ping yang Chen-Ming Dong Dong-Xin Wang Qing-Yuan Zhan Shuang-Lin FU Lin Zhao Qi-bing Huang Ying-Guang Xie Xiao-Bo Huang Guo-Bin Zhang Wang-Bin Xu Yuan Xu YaLing Liu He-Ling Zhao Rong-Qing Sun Ming Sun Qing-Hong Cheng Xin qu Xiao-Feng yang Ming Xu Zhong-Hua Shi Han Chen Xuan He yan-Lin yang Guang-Qiang Chen Xiu-Mei Sun Jian-Xin Zhou department of Critical Care Medicine Beijing Tiantan Hospital Capital Medical University Beijing 100050 China department of Critical Care Medicine Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China department of Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan Ningxia 750004 China department of Critical Care Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China Neurological Intensive Care Unit Beijing Tiantan Hospital Capital Medical University Beijing 100050 China department of Critical Care Medicine Guangdong General Hospital Guangzhou Guangdong 510000 China Surgical Intensive Care Unit Fujian Province Hospital Fuzhou Fujian 350000 China department of Critical Care Medicine First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China department of Critical Care Medicine Bethune International Peace Hospital Shijiazhuang Hebei 050000 China department of Critical Care Medicine Yuncheng Central Hospital Yuncheng Shanxi 044000 China department of Emergency and Critical Care Medicine Cangzhou People's Hospital Cangzhou Hebei 061000 China department of Critical Care Medicine Beijing Luhe Hospital Capital Medical University Beijing 101100 China department of Critical Care Medicine First Hospital of China Medical University Shenyang Liaoning 110000 China department of Critical Care Medicine Shanghai Changzheng Hospital Shanghai 200000 China department of Critical Care Medicine Beijing Shijitan Hospital Capital Medical University Beijing 100038 China department of Critical Care Medicine Xuanwu Hospital Capital Medical University Beijing 100053 China department of Critical Care Medicine Miyun County Hospital Beijing 100038 China Medical Intensive Care Unit Peking Union Medical College Hospital Beijing 101500 China department of Critical Care Medicine Beijing Friendship Hospital Capital Medical University Beijing 100050 Chin

Background： Over the years, the mechanical ventilation （MV） strategy has changed worldwide. The aim of the present study was to describe the ventilation practices, particularly lung-protective ventilation （LPV）, among brain-injured patients in china. Methods： This study was a multicenter, 1-day, cross-sectional study in 47 Intensive Care Units （ICUs） across china. Mechanically ventilated patients （18 years and older） with brain injury in a participating ICU during the time of the study, including traumatic brain injury, stroke, postoperation with intracranial tumor, hypoxic-ischemic encephalopathy, intracranial infection, and idiopathic epilepsy, were enrolled. Demographic data, primary diagnoses, indications for MV, MV modes and settings, and prognoses on the 60th day were collected. Multivariable logistic analysis was used to assess factors that might affect the use of LPV. Results： A total of 104 patients were enrolled in the present study, 87 （83.7%） of whom were identified with severe brain injury based on a Glasgow Coma Scale 〈8 points. Synchronized intermittent mandatory ventilation （SIMV） was the most frequent ventilator mode, accounting for 46.2% of the entire cohort. The median tidal volume was set to 8.0 ml/kg （interquartile range [IQR], 7.0-8.9 ml/kg） of the predicted body weight; 50 （48.1%） patients received LPV. The median positive end-expiratory pressure （PEEP） was set to 5 cmH20 （IQR, 5-5 cmH20）. No PEEP values were higher than 10 cmH20. Compared with partially mandatory ventilation, supportive and spontaneous ventilation practices were associated with LPV. There were no significant differences in mortality and MV duration between patients subjected to LPV and those were not. Conclusions： Among brain-injured patients in china, SIMV was the most frequent ventilation mode. Nearly one-half of the brain-injured patients received LPV. Patients under supportive and spontaneous ventilation were more likely to receive LPV.

关键词： Brain Injury Epidemiology Lung-protective Ventilation Mechanical Ventilation

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied Physics department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal university Beijing Brown university ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china Normal university WuhanHubei Central South university ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering physics MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang university HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china university of Geosciences Beijing china university of Geosciences WuhanHubei china university of Mining and Technology XuzhouJiangsu china West Normal university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu university DalianLiaoning Dalian university of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china university Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

以案例库为基础的早期临床医学教育模式构建及在呼吸内科实践教学中的应用

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中国卫生产业 2018年第4期15卷 119-120页

作者：曲丹华薛颜军任锦闫冰迪刘晓秋杨俊玲张捷刘晶吉林大学第二医院呼吸内科吉林长春130000

目的探讨分析以案例库为基础的早期临床医学教育模式在呼吸内科学生实践教学中的具体应用及教学效果。方法根据教学大纲编写呼吸内科案例库,以吉林大学白求恩医学部2012级临床五年制实习学生60名(采用案例库早期导入教学模式)与2011级... 详细信息

目的探讨分析以案例库为基础的早期临床医学教育模式在呼吸内科学生实践教学中的具体应用及教学效果。方法根据教学大纲编写呼吸内科案例库,以吉林大学白求恩医学部2012级临床五年制实习学生60名(采用案例库早期导入教学模式)与2011级临床五年制实习学生63名(采用传统教学模式)为研究对象,对2组学生及授课教师进行调查问卷及成绩分析。结果建立完成了集文字图片影像于一体的呼吸内科案例库,包含24个呼吸系统典型疾病案例,案例库早期导入教学模式可以提高学生临床学习兴趣;提高学生早期临床思维能力,缩短学生从理论过渡到临床实践的时间;可以提升教师授课水平,提高教学质量,提高教师的教学热情。结论在呼吸内科教学中早期导入案例库教学方法优于传统的教学方法,适于推广及扩大教学。

关键词：医学教育呼吸内科临床实习教学案例库教学

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中国高分子合成化学的研究与发展动态

高分子学报 2019年第10期50卷 1083-1132页

作者：安泽胜陈昶乐何军坡洪春雁李志波李子臣刘超吕小兵秦安军曲程科唐本忠陶友华宛新华王国伟王佳郑轲邹文凯吉林大学化学学院长春130012 中国科学技术大学高分子科学与工程系合肥230026 复旦大学高分子科学系聚合物分子工程国家重点实验室上海200433 青岛科技大学高分子科学与工程学院青岛266042 北京大学化学与分子工程学院北京分子科学国家研究中心北京100871 大连理工大学精细化工国家重点实验室大连116024 华南理工大学发光材料与器件国家重点实验室广州510640 香港科技大学化学系香港中国科学院长春应用化学研究所生态环境高分子材料重点实验室长春130022

高分子合成化学是主要研究高分子量化合物的分子设计、合成和改性等内容的科学,它为人类社会进步、生活水平提高及国家安全提供了必不可少的物质保障.中华人民共和国成立70年来,中国学者为推动此领域的发展作出了积极贡献,在设计合成新... 详细信息

高分子合成化学是主要研究高分子量化合物的分子设计、合成和改性等内容的科学,它为人类社会进步、生活水平提高及国家安全提供了必不可少的物质保障.中华人民共和国成立70年来,中国学者为推动此领域的发展作出了积极贡献,在设计合成新单体和聚合物、研发高效且环境友好新型催化剂、发展新的聚合反应、探索新的聚合方法、优化合成路径、开发聚合新工艺、发现新的结构与性能等方面取得了一系列重要的创新成果.本文总结和评述了中国高分子合成化学的研究与动态,并展望了不同聚合反应、高分子拓扑结构控制以及生物质来源单体的设计、合成与聚合等的未来发展.

关键词：高分子合成化学可控聚合反应自由基聚合反应离子聚合反应配位聚合反应开环聚合反应逐步聚合反应拓扑结构生物质来源单体